Page last updated: 2024-10-28

hydroxyurea and Skin Diseases

hydroxyurea has been researched along with Skin Diseases in 35 studies

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"Between 1980 and 1991, 96 patients with documented polycythemia vera were treated by hydroxyurea or pipobroman, according to a protocol including randomization, and maintenance therapy."9.07[Treatment of polycythemia vera with hydroxyurea or pipobroman. Efficacy and toxicity analysed from a protocol of 96 patients under 65 years of age. Le Groupe d'Etude des Polyglobulies]. ( Najean, Y, 1992)
"Treatment with hydroxyurea was followed by a marked reduction in spleen size, a decrease in white cell count and healing of the skin lesions."5.26Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case. ( Atamer, MA; Friedhoff, FW; Thelmo, WL, 1978)
"Between 1980 and 1991, 96 patients with documented polycythemia vera were treated by hydroxyurea or pipobroman, according to a protocol including randomization, and maintenance therapy."5.07[Treatment of polycythemia vera with hydroxyurea or pipobroman. Efficacy and toxicity analysed from a protocol of 96 patients under 65 years of age. Le Groupe d'Etude des Polyglobulies]. ( Najean, Y, 1992)
"Our rate of hydroxyurea-induced leg ulcers (29%) is higher than that reported for patients with myeloproliferative syndromes (9%)."3.71Cutaneous adverse reactions to hydroxyurea in patients with sickle cell disease. ( Aractingi, S; Chaine, B; Girot, R; Neonato, MG, 2001)
" However, these agents also place patients at increased risk for drug-related cutaneous adverse events."2.66Drug-Related Cutaneous Adverse Events in Philadelphia Chromosome-Negative Myeloproliferative Neoplasms: A Literature Review. ( Guglielmelli, P; Malato, A; Palumbo, GA; Pugliese, N; Rossi, E, 2020)
" On long-term use (2-15 years) of 1500-2000 mg a day, there is a 9% risk of developing ulcers."1.56[An 84-year-old man with an ulcer on his ankle]. ( Houwing, RH; Sanders-Koers, R; van Berkum-Zandkamp, N, 2020)
"The hypereosinophilic syndrome is a multi-organ disease characterized by large counts of eosinophils in peripheral blood observed during at least six months without any evidence for other known causes of eosinophilia."1.33[The hypereosinophilic syndrome: case report]. ( Grzybowski, G; Mikołajczyk, K; Samborski, W; Walkowiak, B; Zaba, R, 2006)
"Hydroxyurea is a treatment of myeloproliferative syndromes."1.31[Secondary cutaneous effects of hydroxyurea: prospective study of 26 patients from a dermatologic consultation]. ( Bernard, P; Leborgne, G; Potron, G; Salmon-Ehr, V; Vilque, JP, 2000)
"Nonspecific cutaneous xanthomas have occasionally been reported with a variety of leukemias, mostly in the pediatric literature, but the first report (to our knowledge) of acute myelomonocytic leukemia presenting with specific cutaneous xanthomatous lesions appeared in 1982."1.27Cutaneous xanthomas associated with chronic myelomonocytic leukemia. ( Adler, KR; Rothenberg, J; Vail, JT, 1985)
"Treatment with hydroxyurea was followed by a marked reduction in spleen size, a decrease in white cell count and healing of the skin lesions."1.26Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case. ( Atamer, MA; Friedhoff, FW; Thelmo, WL, 1978)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199011 (31.43)18.7374
1990's5 (14.29)18.2507
2000's11 (31.43)29.6817
2010's4 (11.43)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
van Berkum-Zandkamp, N1
Houwing, RH1
Sanders-Koers, R1
Malato, A1
Rossi, E1
Palumbo, GA1
Guglielmelli, P1
Pugliese, N1
Stegelmann, F2
Wille, K2
Busen, H1
Fuchs, C1
Schauer, S1
Sadjadian, P2
Becker, T1
Kolatzki, V1
Döhner, H1
Stadler, R1
Döhner, K2
Griesshammer, M2
Cozzani, E1
Iurlo, A1
Merlo, G1
Cattaneo, D1
Burlando, M1
Pierri, I1
Gugliotta, L1
Parodi, A1
Grandi, V1
Delfino, C1
Pimpinelli, N1
Dem, A1
Diallo, M1
Gaye Fall, MC1
Dieng, MM1
Gaye, M1
Touré, P1
Latagliata, R1
Spadea, A1
Cedrone, M1
Di Giandomenico, J1
De Muro, M1
Villivà, N1
Breccia, M1
Anaclerico, B1
Porrini, R1
Spirito, F1
Rago, A1
Avvisati, G1
Alimena, G1
Montanaro, M1
Andriani, A1
Bartolucci, P1
Galactéros, F1
Belgi, G1
Friedmann, PS1
Bravo Blanco, AM1
Moral, JL1
Tembrás, S1
Gómez, R1
Ulibarrena, C1
Obdulia Vazquez, M1
Sanchez-Palacios, C1
Guitart, J1
Mikołajczyk, K1
Zaba, R1
Walkowiak, B1
Grzybowski, G1
Samborski, W1
Pfeifle, CE1
Howell, SB1
Spry, CJ1
van Genderen, PJ1
Michiels, JJ1
van der Poel-van de Luytgaarde, SC1
van Vliet, HH1
Koike, M1
Ishiyama, T1
Salmon-Ehr, V2
Grosieux, C1
Potron, G2
Kalis, B1
Leborgne, G1
Vilque, JP1
Bernard, P1
Young, HS1
Khan, AS1
Kendra, JR1
Coulson, IH1
Laughon, SK1
Shinn, LL1
Nunley, JR1
Chaine, B1
Neonato, MG1
Girot, R1
Aractingi, S1
O'branski, EE1
Ware, RE1
Prose, NS1
Kinney, TR1
Tanaka, M1
Kanamori, H1
Yamaji, S1
Mishima, A1
Yamazaki, E1
Taguchi, J1
Aoba, M1
Fujisawa, S1
Mohri, H1
Ishigatsubo, Y1
McMeekin, TO1
Moschella, SL1
Friedhoff, FW1
Atamer, MA1
Thelmo, WL1
Najean, Y1
Hillyer, MH1
Mair, TS1
Osterwalder, B1
Schmid, L1
Jungi, WF1
Flury, R1
Schmid, U1
Staub, P1
Senn, HJ1
Zaumseil, RP1
Taube, KM1
Vail, JT1
Adler, KR1
Rothenberg, J1
Dantzig, PI1
Lèques, B1
Texier, L1
Verdaguer, S1
Hoffman-Martinot, R1
Paulet, C1
Moine, M1
Richards, GJ1
Chambers, RG1

Reviews

10 reviews available for hydroxyurea and Skin Diseases

ArticleYear
Drug-Related Cutaneous Adverse Events in Philadelphia Chromosome-Negative Myeloproliferative Neoplasms: A Literature Review.
    International journal of molecular sciences, 2020, May-30, Volume: 21, Issue:11

    Topics: Humans; Hydroxyurea; Interferons; Janus Kinase Inhibitors; Keratosis, Actinic; Myeloproliferative Di

2020
A review of hydroxyurea-related cutaneous adverse events.
    Expert opinion on drug safety, 2021, Volume: 20, Issue:12

    Topics: Anemia, Sickle Cell; Antineoplastic Agents; Humans; Hydroxyurea; Myeloproliferative Disorders; Skin

2021
Essential Thrombocythemia: The Dermatologic Point of View.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:12

    Topics: Antineoplastic Agents; Humans; Hydroxyurea; Interferon-alpha; Quinazolines; Skin Diseases; Thrombocy

2015
Clinical management of adult sickle-cell disease.
    Current opinion in hematology, 2012, Volume: 19, Issue:3

    Topics: Anemia, Sickle Cell; Antisickling Agents; Humans; Hydroxyurea; Hypertension, Pulmonary; Kidney Disea

2012
Traditional therapies: glucocorticoids, azathioprine, methotrexate, hydroxyurea.
    Clinical and experimental dermatology, 2002, Volume: 27, Issue:7

    Topics: Azathioprine; Dermatologic Agents; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; M

2002
Hydroxyurea-associated squamous dysplasia.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Humans; Hydroxyurea; Keratosis; Male; Precancerous Conditions; Skin

2004
The hypereosinophilic syndrome: clinical features, laboratory findings and treatment.
    Allergy, 1982, Volume: 37, Issue:8

    Topics: Anticoagulants; Bone Marrow; Central Nervous System Diseases; Endomyocardial Fibrosis; Eosinophilia;

1982
[Hypereosinophilic syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:3

    Topics: Adult; Aged; Cardiovascular Diseases; Eosinophilia; Female; Humans; Hydroxyurea; Leukemia, Eosinophi

1993
Iatrogenic complications of dermatologic therapy. Primum non nocere.
    The Medical clinics of North America, 1979, Volume: 63, Issue:2

    Topics: Adrenal Cortex Hormones; Azathioprine; Cryosurgery; Cyclophosphamide; Electrosurgery; Erythromycin;

1979
Immunosuppressive and cytotoxic drugs in dermatology.
    Archives of dermatology, 1974, Volume: 110, Issue:3

    Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide;

1974

Trials

1 trial available for hydroxyurea and Skin Diseases

ArticleYear
[Treatment of polycythemia vera with hydroxyurea or pipobroman. Efficacy and toxicity analysed from a protocol of 96 patients under 65 years of age. Le Groupe d'Etude des Polyglobulies].
    Presse medicale (Paris, France : 1983), 1992, Nov-07, Volume: 21, Issue:37

    Topics: Digestive System Diseases; Female; Follow-Up Studies; Humans; Hydroxyurea; Male; Middle Aged; Pipobr

1992

Other Studies

24 other studies available for hydroxyurea and Skin Diseases

ArticleYear
[An 84-year-old man with an ulcer on his ankle].
    Nederlands tijdschrift voor geneeskunde, 2020, 04-02, Volume: 164

    Topics: Aged, 80 and over; Ankle; Antineoplastic Agents; Hematologic Neoplasms; Humans; Hydroxyurea; Long Te

2020
Significant association of cutaneous adverse events with hydroxyurea: results from a prospective non-interventional study in BCR-ABL1-negative myeloproliferative neoplasms (MPN) - on behalf of the German Study Group-MPN.
    Leukemia, 2021, Volume: 35, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Follow-Up Studies; Fusion Proteins, b

2021
Ingenol mebutate in the treatment of 'Hydroxyurea-induced Squamous Dysplasia': a single centre experience.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2016, Volume: 30, Issue:7

    Topics: Aged; Diterpenes; Female; Humans; Hydroxyurea; Male; Middle Aged; Skin; Skin Diseases

2016
[Cutaneous complications of long-term hydroxyurea therapy].
    Annales de dermatologie et de venereologie, 2008, Volume: 135, Issue:11

    Topics: Adult; Alopecia; Antineoplastic Agents; Atrophy; Female; Hand; Humans; Hydroxyurea; Leukemia, Myelog

2008
Symptomatic mucocutaneous toxicity of hydroxyurea in Philadelphia chromosome-negative myeloproliferative neoplasms: the Mister Hyde face of a safe drug.
    Cancer, 2012, Jan-15, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Middle Age

2012
Hydroxyurea-induced skin ulcerations in patients with chronic myeloproliferative disorders.
    Journal of hematotherapy & stem cell research, 2003, Volume: 12, Issue:4

    Topics: Aged; DNA; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Leg Ulcer; Male; Middle Aged; Myeloprolif

2003
[The hypereosinophilic syndrome: case report].
    Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2

    Topics: Adult; Benzamides; Bone Marrow; Diagnosis, Differential; Eosinophils; Humans; Hydroxyurea; Hypereosi

2006
Phase I trial of cytarabine and hydroxyurea.
    Cancer treatment reports, 1983, Volume: 67, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Child; Cy

1983
Acquired von Willebrand disease as a cause of recurrent mucocutaneous bleeding in primary thrombocythemia: relationship with platelet count.
    Annals of hematology, 1994, Volume: 69, Issue:2

    Topics: Adult; Bleeding Time; Female; Hemorrhage; Humans; Hydroxyurea; Mucous Membrane; Platelet Count; Skin

1994
Multiple actinic keratosis and skin tumors secondary to hydroxyurea treatment.
    Dermatology (Basel, Switzerland), 1998, Volume: 196, Issue:2

    Topics: Aged; Antineoplastic Agents; Busulfan; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Hydr

1998
[Secondary cutaneous effects of hydroxyurea: prospective study of 26 patients from a dermatologic consultation].
    La Revue de medecine interne, 2000, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Humans; Hydroxyurea; Leg Ulcer; Myeloproliferative

2000
The cutaneous side-effects of hydroxyurea.
    Clinical and laboratory haematology, 2000, Volume: 22, Issue:4

    Topics: Aged; Alopecia; Carcinoma, Squamous Cell; Female; Humans; Hydroxyurea; Keratosis; Polycythemia Vera;

2000
Melanonychia and mucocutaneous hyperpigmentation due to hydroxyurea use in an HIV-infected patient.
    International journal of dermatology, 2000, Volume: 39, Issue:12

    Topics: Antiviral Agents; Female; HIV Infections; Humans; Hydroxyurea; Hyperpigmentation; Melanosis; Middle

2000
Cutaneous adverse reactions to hydroxyurea in patients with sickle cell disease.
    Archives of dermatology, 2001, Volume: 137, Issue:4

    Topics: Adult; Age Factors; Anemia, Sickle Cell; Antisickling Agents; Female; Humans; Hydroxyurea; Leg Ulcer

2001
Skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy.
    Journal of the American Academy of Dermatology, 2001, Volume: 44, Issue:5

    Topics: Adolescent; Anemia, Sickle Cell; Antisickling Agents; Child; Female; Humans; Hydroxyurea; Hyperpigme

2001
Subcutaneous extramedullary hematopoiesis in a patient with secondary myelofibrosis following polycythemia vera.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Aged; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Megakaryocytes; Myeloid Cells; Pol

2001
Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case.
    Chemotherapy, 1978, Volume: 24, Issue:5

    Topics: Female; Humans; Hydroxyurea; Leukemia, Myeloid; Middle Aged; Primary Myelofibrosis; Punctures; Skin

1978
Multisystemic eosinophilic epitheliotropic disease in a horse: attempted treatment with hydroxyurea and dexamethasone.
    The Veterinary record, 1992, May-02, Volume: 130, Issue:18

    Topics: Animals; Dexamethasone; Eosinophilia; Epithelium; Female; Gastrointestinal Diseases; Horse Diseases;

1992
[Myeloproliferative syndrome and acute febrile neutrophilic dermatosis (Sweet's syndrome)--a rare association].
    Schweizerische medizinische Wochenschrift, 1987, Nov-28, Volume: 117, Issue:48

    Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Fever; Humans; Hydroxyurea; Male; Myeloproliferative D

1987
[Coexistence of psoriasis vulgaris and porphyria cutanea tarda in a patient treated with hydroxycarbamid. Case report].
    Dermatologische Monatschrift, 1986, Volume: 172, Issue:3

    Topics: Humans; Hydroxyurea; Male; Middle Aged; Porphyrias; Psoriasis; Skin Diseases

1986
Cutaneous xanthomas associated with chronic myelomonocytic leukemia.
    Archives of dermatology, 1985, Volume: 121, Issue:10

    Topics: Adult; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Prednisone; Skin Diseases; Xanthomatosis

1985
[A new etiology of inflammatory livedo: thrombocytosis].
    La Presse medicale, 1969, Jan-18, Volume: 77, Issue:3

    Topics: Arteritis; Busulfan; Diagnosis, Differential; Erythromelalgia; Female; Foot Dermatoses; Humans; Hydr

1969
Anaflex and noxyflex: low-toxicity antiseptics.
    Drug and therapeutics bulletin, 1970, Oct-23, Volume: 8, Issue:20

    Topics: Anti-Infective Agents, Local; Female; Formaldehyde; Humans; Hydroxyurea; Skin Diseases; Thiourea; Ur

1970
Hydroxyurea: a radiosensitizer in the treatment of neoplasms of the head and neck.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1969, Volume: 105, Issue:3

    Topics: Adult; Age Factors; Aged; Female; Gastrointestinal Diseases; Head; Head and Neck Neoplasms; Hematolo

1969