hydroxyurea has been researched along with Proteinuria in 12 studies
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We are unsure if hydroxyurea improves glomerular filtration rate or reduces hyperfiltration in children aged nine to 18 months, but it may improve their ability to concentrate urine and may make little or no difference to the incidence of acute chest syndrome, painful crises, and hospitalisations." | 5.41 | Interventions for chronic kidney disease in people with sickle cell disease. ( Carpenter, A; Dale-Harris, I; Dorée, C; Estcourt, LJ; Roy, NB, 2023) |
| " ACE inhibition and hydroxyurea decrease proteinuria so they may limit progression of chronic kidney disease." | 3.88 | Sickle cell disease: a case report of renal amyloidosis. ( Blanco, P; Bugeja, A; Clark, EG; Sood, MM, 2018) |
| "Hydroxyurea treatment augmented plasma nitrite and attenuated plasma arginase in HbSS mice." | 1.62 | Hydroxyurea improves nitric oxide bioavailability in humanized sickle cell mice. ( Dunaway, LS; Kasztan, M; Molina, PA; Pollock, DM; Pollock, JS; Sedaka, R; Taylor, CM, 2021) |
| " 70C and 360C were dosed to female Wistar rats at 100 mg/kg po daily for 7 days." | 1.30 | Structure-activity relationship for two lipoxygenase inhibitors and their potential for inducing nephrotic syndrome. ( Evans, GO; Goodwin, DA; Hawksworth, GM; Hodgson, ST; Morley, TJ; Read, NG, 1997) |
| " Detailed examination of the lesion in animals dosed with 225C showed that there was a clear relationship between the onset of the lesion and the dose given, i." | 1.29 | Nephrotic syndrome associated with N-hydroxyureas, inhibitors of 5-lipoxygenase. ( Astbury, PJ; Evans, GO; Goodwin, DA; Read, NG; Rowlands, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Roy, NB | 1 |
| Carpenter, A | 1 |
| Dale-Harris, I | 1 |
| Dorée, C | 1 |
| Estcourt, LJ | 1 |
| Taylor, CM | 1 |
| Kasztan, M | 1 |
| Sedaka, R | 1 |
| Molina, PA | 1 |
| Dunaway, LS | 1 |
| Pollock, JS | 1 |
| Pollock, DM | 1 |
| Bugeja, A | 1 |
| Blanco, P | 1 |
| Clark, EG | 1 |
| Sood, MM | 1 |
| Silva Junior, GB | 1 |
| Vieira, AP | 1 |
| Couto Bem, AX | 1 |
| Alves, MP | 1 |
| Meneses, GC | 1 |
| Martins, AM | 1 |
| Araújo, SM | 1 |
| Libório, AV | 1 |
| Daher, EF | 1 |
| Artz, N | 1 |
| Whelan, C | 1 |
| Feehan, S | 1 |
| Valdivielso, JM | 1 |
| Montero, A | 1 |
| Munger, KA | 1 |
| Badr, KF | 1 |
| Iyoda, M | 1 |
| Ito, J | 1 |
| Ajiro, Y | 1 |
| Nagai, H | 1 |
| Uchida, J | 1 |
| Honda, H | 1 |
| Kuroki, A | 1 |
| Shibata, T | 1 |
| Kitazawa, K | 1 |
| Sugisaki, T | 1 |
| McKie, KT | 1 |
| Hanevold, CD | 1 |
| Hernandez, C | 1 |
| Waller, JL | 1 |
| Ortiz, L | 1 |
| McKie, KM | 1 |
| Spry, CJ | 1 |
| Read, NG | 2 |
| Astbury, PJ | 1 |
| Evans, GO | 2 |
| Goodwin, DA | 2 |
| Rowlands, A | 1 |
| Morley, TJ | 1 |
| Hodgson, ST | 1 |
| Hawksworth, GM | 1 |
| Page, RL | 1 |
| Stiff, ME | 1 |
| McEntee, MC | 1 |
| Walter, LG | 1 |
2 reviews available for hydroxyurea and Proteinuria
| Article | Year |
|---|---|
Interventions for chronic kidney disease in people with sickle cell disease.
Topics: Acute Chest Syndrome; Adolescent; Adult; Anemia, Sickle Cell; Angiotensin-Converting Enzyme Inhibito | 2023 |
The hypereosinophilic syndrome: clinical features, laboratory findings and treatment.
Topics: Anticoagulants; Bone Marrow; Central Nervous System Diseases; Endomyocardial Fibrosis; Eosinophilia; | 1982 |
10 other studies available for hydroxyurea and Proteinuria
| Article | Year |
|---|---|
Hydroxyurea improves nitric oxide bioavailability in humanized sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Arginase; Disease Models, Animal; Hemoglobin A; H | 2021 |
Sickle cell disease: a case report of renal amyloidosis.
Topics: Adult; Amyloidosis; Anemia, Sickle Cell; Angiotensin-Converting Enzyme Inhibitors; Antibodies; DNA; | 2018 |
Proteinuria in adults with sickle-cell disease: the role of hydroxycarbamide(hydroxyurea) as a protective agent.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Brazil; Cohort Studies; Female; Glomerular Filtrati | 2014 |
Caring for the adult with sickle cell disease: results of a multidisciplinary pilot program.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Chi-Square Distribution; Female; Humans; Hydroxyure | 2010 |
Inhibition of 5-LO activating protein (FLAP) activity decreases proteinuria in streptozotocin (STZ)-induced diabetic rats.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Blood Glucose; Blood Urea Nitrogen; Carrier Proteins; D | 2002 |
[Focal segmental glomerulosclerosis in a patient with polycythemia vera].
Topics: Aged; Disease Progression; Female; Glomerulosclerosis, Focal Segmental; Humans; Hydroxyurea; Nitroso | 2005 |
Prevalence, prevention, and treatment of microalbuminuria and proteinuria in children with sickle cell disease.
Topics: Adolescent; Adult; Age of Onset; Albuminuria; Anemia, Sickle Cell; Angiotensin-Converting Enzyme Inh | 2007 |
Nephrotic syndrome associated with N-hydroxyureas, inhibitors of 5-lipoxygenase.
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Body Weight; Chromatography, High Pressure L | 1995 |
Structure-activity relationship for two lipoxygenase inhibitors and their potential for inducing nephrotic syndrome.
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Blood Proteins; Cholesterol; Creatinine; | 1997 |
Transient glomerulonephropathy associated with primary erythrocytosis in a dog.
Topics: Animals; Bloodletting; Combined Modality Therapy; Dog Diseases; Dogs; Doxorubicin; Female; Hydroxyur | 1990 |