hydroxyurea has been researched along with Prostatic Neoplasms in 21 studies
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A number of chemotherapeutic agents, including L-asparaginase, actinomycin D, chloroethylcyclohexy-nitrosourea, 5-flourouracil, cyclophosphamide, hydroxyurea, cis-platinum, adriamycin and methotrexate, alone and in combination and at variable dose levels, were applied against the Dunning R3327 rat prostatic adenocarcinoma-subline G." | 3.66 | Further experience with chemotherapy in the Dunning prostatic adenocarcinoma. ( Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M, 1978) |
| "The expression of 5-LOX in the metastasis sample was notably greater than that in the tumors in situ." | 1.39 | Inhibitor of 5-lipoxygenase, zileuton, suppresses prostate cancer metastasis by upregulating E-cadherin and paxillin. ( Cao, R; Liu, T; Meng, Z; Wang, X; Wang, Y; Yang, Z, 2013) |
| " Using pharmacokinetic data obtained during the course of a clinical trial of hydroxyurea, we simulated a dosing regimen that would sustain plasma drug concentrations above 100 microM for 120 h (1 g loading dose, followed by 500 mg every 6 h for 5 days in a 70 kg man)." | 1.29 | In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate. ( Cooper, MR; Figg, WD; McCall, NA; Myers, CE; Samid, D; Sartor, O; Thibault, A; Walls, RG, 1994) |
| "mm." | 1.26 | Hydroxyurea in stage D carcinoma of prostate. ( Lerner, HJ; Malloy, TR, 1977) |
| "mm." | 1.25 | Hydroxyurea in stage D carcinoma of the prostate: a pilot study. ( Cromie, W; Lerner, H; Longo, S; Malloy, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, R | 1 |
| Maekawa, M | 1 |
| Hieda, M | 1 |
| Taguchi, T | 1 |
| Miura, N | 1 |
| Kikugawa, T | 1 |
| Saika, T | 1 |
| Higashiyama, S | 1 |
| Meng, Z | 1 |
| Cao, R | 1 |
| Yang, Z | 1 |
| Liu, T | 1 |
| Wang, Y | 1 |
| Wang, X | 1 |
| HOWE, CD | 1 |
| SAMUELS, ML | 1 |
| Zhou, B | 1 |
| Liu, X | 1 |
| Mo, X | 1 |
| Xue, L | 1 |
| Darwish, D | 1 |
| Qiu, W | 1 |
| Shih, J | 1 |
| Hwu, EB | 1 |
| Luh, F | 1 |
| Yen, Y | 1 |
| Stephens, RL | 1 |
| Vaughn, C | 1 |
| Lane, M | 1 |
| Costanzi, J | 1 |
| O'Bryan, R | 1 |
| Balcerzak, SP | 1 |
| Levin, H | 1 |
| Frank, J | 1 |
| Coltman, CA | 1 |
| Schmidt, JD | 3 |
| Scott, WW | 2 |
| Gibbons, R | 1 |
| Johnson, DE | 2 |
| Prout, GR | 2 |
| Loening, S | 1 |
| Soloway, M | 1 |
| deKernion, JB | 1 |
| Pontes, JE | 2 |
| Slack, NH | 2 |
| Murphy, GP | 3 |
| Loening, SA | 1 |
| deKernion, J | 1 |
| Gibbons, RP | 1 |
| Soloway, MS | 1 |
| Chu, TM | 1 |
| Gaeta, JF | 1 |
| Mundy, AR | 1 |
| Santarossa, S | 1 |
| Vaccher, E | 1 |
| Lenardon, O | 1 |
| Merlo, A | 1 |
| Errante, D | 1 |
| Tirelli, U | 1 |
| Figg, WD | 1 |
| Walls, RG | 1 |
| Cooper, MR | 1 |
| Thibault, A | 1 |
| Sartor, O | 1 |
| McCall, NA | 1 |
| Myers, CE | 1 |
| Samid, D | 1 |
| Sprenger, CC | 1 |
| Damon, SE | 1 |
| Hwa, V | 1 |
| Rosenfeld, RG | 1 |
| Plymate, SR | 1 |
| Yang, CC | 1 |
| Hsu, CP | 1 |
| Yang, SD | 1 |
| Carter, SK | 1 |
| Wasserman, TH | 1 |
| Block, NL | 1 |
| Camuzzi, F | 1 |
| Stover, B | 1 |
| Claflin, A | 1 |
| Troner, M | 1 |
| Politano, VA | 1 |
| Lerner, HJ | 1 |
| Malloy, TR | 1 |
| Lerner, H | 1 |
| Malloy, T | 1 |
| Cromie, W | 1 |
| Longo, S | 1 |
| Portnoĭ, AS | 1 |
| Scott, FM | 1 |
| Sator de Serrano, V | 1 |
| Castellino, FJ | 1 |
| Pavone-Macaluso, M | 1 |
1 review available for hydroxyurea and Prostatic Neoplasms
| Article | Year |
|---|---|
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; | 1985 |
5 trials available for hydroxyurea and Prostatic Neoplasms
| Article | Year |
|---|---|
Adriamycin and cyclophosphamide versus hydroxyurea in advanced prostatic cancer. A randomized Southwest Oncology Group study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Do | 1984 |
A comparison of hydroxyurea, methyl-chloroethyl-cyclohexy-nitrosourea and cyclophosphamide in patients with advanced carcinoma of the prostate.
Topics: Acid Phosphatase; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Hu | 1981 |
A pilot study of hydroxyurea in hormone "escaped" metastatic carcinoma of the prostate.
Topics: Aged; Clinical Trials as Topic; Diethylstilbestrol; Humans; Hydroxyurea; Male; Middle Aged; Prognosi | 1982 |
Ribonucleotide reductase inhibition in the treatment of advanced prostate cancer: an experimental approach with hydroxyurea and gallium nitrate in 20 patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Gallium; Humans; Hydroxyure | 1995 |
[Chemotherapy of advanced prostate cancer].
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Eval | 1977 |
15 other studies available for hydroxyurea and Prostatic Neoplasms
| Article | Year |
|---|---|
SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
Topics: Cell Death; Cell Nucleus; DNA Cleavage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; | 2020 |
Inhibitor of 5-lipoxygenase, zileuton, suppresses prostate cancer metastasis by upregulating E-cadherin and paxillin.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cadherins; Cell Migration Assays; Enzyme-Linked Immunosorbent | 2013 |
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: UROLOGIC AND GYNECOLOGIC NEOPLASMS.
Topics: Adenocarcinoma; Anemia; Anemia, Aplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Ther | 1964 |
The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.
Topics: Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA Repair; Gene Expression Regulation, Neoplasti | 2003 |
Chemotherapy programs of the National Prostatic Cancer Project (NPCP).
Topics: Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Evaluation; Drug Ther | 1980 |
Chemotherapy of hormone-resistant stage D prostatic cancer.
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; E | 1980 |
In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate.
Topics: Cell Division; Cell Survival; Drug Synergism; Hormones; Humans; Hydroxyurea; Kinetics; Male; Models, | 1994 |
Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) is a potential tumor suppressor protein for prostate cancer.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Division; Cell Size; DNA, Complementary; Genes, Tumor Sup | 1999 |
Antisense suppression of proline-directed protein kinase FA enhances chemosensitivity in human prostate cancer cells.
Topics: Antineoplastic Agents; Carboplatin; Cell Survival; Cisplatin; DNA, Antisense; DNA, Complementary; DN | 2000 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Co | 1975 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxoru | 1978 |
Hydroxyurea in stage D carcinoma of prostate.
Topics: Aged; Chlorotrianisene; Drug Therapy, Combination; Humans; Hydroxyurea; Male; Middle Aged; Neoplasm | 1977 |
Hydroxyurea in stage D carcinoma of the prostate: a pilot study.
Topics: Adenocarcinoma; Aged; Anemia; Bone Neoplasms; Chlorotrianisene; Estrogens; Humans; Hydroxyurea; Leuk | 1975 |
Appearance of plasminogen activator activity during a synchronous cycle of a rat adenocarcinoma cell line, PA-III.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Line; Clone Cells; DNA Replication; Hydroxyurea; Kinetics; | 1987 |
Chemotherapy of vesical and prostatic tumours.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubic | 1971 |