Page last updated: 2024-10-28

hydroxyurea and Primary Myelofibrosis

hydroxyurea has been researched along with Primary Myelofibrosis in 140 studies

Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

Research Excerpts

ExcerptRelevanceReference
"Hydroxyurea (HU) treatment of patients with essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) (MPNs) normalizes elevated blood cell counts within weeks in the large majority of patients."9.41Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis. ( Andersen, M; Dam, MJB; Hasselbalch, HC; Kjaer, L; Knudsen, TA; Ottesen, JT; Pedersen, RK; Skov, V, 2021)
"Hydroxyurea is the standard treatment in high-risk patients with polycythemia vera."9.01Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis. ( Barbui, T; Carobbio, A; De Stefano, V; Ferrari, A; Finazzi, G; Ghirardi, A; Masciulli, A; Vannucchi, AM, 2019)
"A 73-year-old man with primary myelofibrosis (PMF) was being treated with hydroxyurea, which was changed to ruxolitinib treatment because of worsening constitutional symptoms."8.98Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature. ( Ikeda, M; Kiyasu, J; Ogawa, Y; Shiratsuchi, M; Tsuda, M; Tsukamoto, Y; Yufu, Y, 2018)
"Medication-induced dermatomyositis (DM) is rare, but a recent review highlighted hydroxyurea (HU) as the most common inciting agent."8.88Hydroxyurea induced dermatomyositis-like eruption. ( Muir, J; Rodins, K; Zappala, TM, 2012)
"Ruxolitinib is approved for patients with polycythemia vera (PV) who are resistant/intolerant to hydroxyurea, but its impact on preventing thrombosis or disease-progression is unknown."8.12Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea. ( Alvarez-Larrán, A; Angona, A; Arellano-Rodrigo, E; Ayala, R; Bellosillo, B; Caballero, G; Carreño-Tarragona, G; Cuevas, B; Del Orbe-Barreto, R; Ferrer-Marín, F; Fox, ML; García, R; García-Gutiérrez, V; García-Hernández, C; Garrote, M; Gasior, M; Gómez, M; Gómez-Casares, MT; Guerrero, L; Hernández-Boluda, JC; Magro, E; Martínez, CM; Mata-Vazquez, MI; Murillo, I; Pereira, A; Pérez-Encinas, M; Pérez-López, R; Ramírez, MJ; Raya, JM; Xicoy, B, 2022)
"Eighty-three patients with various chronic myeloproliferative disorders [polycythemia vera (PV), essential thrombocytosis (ET), idiopathic myelofibrosis (IMF)] were analyzed for the occurrence of acute myeloid leukemia (AML) and myelodysplasia (MDS) during treatment with hydroxyurea (HU) alone or HU following treatment with busulphan (BU)."7.72Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. ( Hasselbalch, HC; Nielsen, I, 2003)
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."7.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
"We report four cases of cutaneous lower leg ulcers associated with hydroxyurea treatment for myeloproliferative disorders."7.68Hydroxyurea and lower leg ulcers. ( Margolis, DJ; Nguyen, TV, 1993)
"An analysis of the risk of progression towards leukemia, carcinoma and myelofibrosis was performed in 93 patients treated by 32P alone (PVSG protocols) since 1970-1979, 395 patients over the age of 65 years treated by 32P with or without maintenance therapy using hydroxyurea (French protocol) since 1980-1994, and 202 patients under the age of 65 treated by either hydroxyurea or pipobroman since 1980."6.18Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias". ( Dresch, C; Echard, M; Goguel, A; Grange, MJ; Lejeune, F; Najean, Y; Rain, JD, 1996)
"Paediatric primary myelofibrosis (PMF) is exceedingly rare and distinct compared with adult PMF."5.91Complete resolution of primary myelofibrosis in an infant with steroids and hydroxyurea. ( Khera, S; Misra, P; Singh, K; Tripathi, P, 2023)
"Hydroxyurea (HU) treatment of patients with essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) (MPNs) normalizes elevated blood cell counts within weeks in the large majority of patients."5.41Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis. ( Andersen, M; Dam, MJB; Hasselbalch, HC; Kjaer, L; Knudsen, TA; Ottesen, JT; Pedersen, RK; Skov, V, 2021)
"A case of idiopathic myelofibrosis presenting with a pleural effusion secondary to extramedullary haemopoeisis is described."5.30Pleural effusion secondary to extramedullary haemopoiesis in a patient with idiopathic myelofibrosis responding to pleurodesis and hydroxyurea. ( Burke, DK; Cryer, RJ; Jowitt, SN; Leggat, HM; Lewis, PS, 1997)
"Treatment with hydroxyurea was followed by a marked reduction in spleen size, a decrease in white cell count and healing of the skin lesions."5.26Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case. ( Atamer, MA; Friedhoff, FW; Thelmo, WL, 1978)
" As compared with hydroxyurea plus aspirin, anagrelide plus aspirin was associated with increased rates of arterial thrombosis (P=0."5.11Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. ( Bareford, D; Buck, G; Campbell, PJ; East, CL; Green, AR; Grigg, AP; Harrison, CN; Reilly, JT; Revell, P; van der Walt, JD; Wheatley, K; Wilkins, BS; Woodcock, BE, 2005)
"Hydroxyurea is the standard treatment in high-risk patients with polycythemia vera."5.01Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis. ( Barbui, T; Carobbio, A; De Stefano, V; Ferrari, A; Finazzi, G; Ghirardi, A; Masciulli, A; Vannucchi, AM, 2019)
"A 73-year-old man with primary myelofibrosis (PMF) was being treated with hydroxyurea, which was changed to ruxolitinib treatment because of worsening constitutional symptoms."4.98Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature. ( Ikeda, M; Kiyasu, J; Ogawa, Y; Shiratsuchi, M; Tsuda, M; Tsukamoto, Y; Yufu, Y, 2018)
" An algorithm for the treatment of patients with erythremia is proposed along with recommendations on the use of aspirin, hydroxyurea, alpha-interpheron, and imatinib."4.88[True polycythemia: current views of pathogenesis, diagnostics and treatment]. ( Bakhteeva, TD; Kalinkina, NV; Skliannaia, EV; Taradin, GG; Vatutin, NT, 2012)
"Medication-induced dermatomyositis (DM) is rare, but a recent review highlighted hydroxyurea (HU) as the most common inciting agent."4.88Hydroxyurea induced dermatomyositis-like eruption. ( Muir, J; Rodins, K; Zappala, TM, 2012)
" Randomized studies have shown that the risk of thrombosis was significantly reduced in ET with the use of hydroxyurea (HU) and in PV with the use of chlorambucil or 32P."4.80Treatment of polycythaemia vera and essential thrombocythaemia. ( Silverstein, MN; Tefferi, A, 1998)
" Treatment selection is based on a patient's age and a history of thrombosis in patients with low-risk PV treated with therapeutic phlebotomy and aspirin alone, whereas cytoreductive therapy with either hydroxyurea or interferon alfa (IFN-α) is added for high-risk disease."4.31Moving toward disease modification in polycythemia vera. ( Bewersdorf, JP; Bose, P; How, J; Masarova, L; Mascarenhas, J; Pemmaraju, N; Rampal, RK, 2023)
"Ruxolitinib is approved for patients with polycythemia vera (PV) who are resistant/intolerant to hydroxyurea, but its impact on preventing thrombosis or disease-progression is unknown."4.12Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea. ( Alvarez-Larrán, A; Angona, A; Arellano-Rodrigo, E; Ayala, R; Bellosillo, B; Caballero, G; Carreño-Tarragona, G; Cuevas, B; Del Orbe-Barreto, R; Ferrer-Marín, F; Fox, ML; García, R; García-Gutiérrez, V; García-Hernández, C; Garrote, M; Gasior, M; Gómez, M; Gómez-Casares, MT; Guerrero, L; Hernández-Boluda, JC; Magro, E; Martínez, CM; Mata-Vazquez, MI; Murillo, I; Pereira, A; Pérez-Encinas, M; Pérez-López, R; Ramírez, MJ; Raya, JM; Xicoy, B, 2022)
" 2004 and treated with hydroxyurea (HU), was admitted to our hospital on March 2005 because of dyspnea and pleural effusion on the right side."3.73[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis]. ( Dan, K; Inokuchi, K; Nakamura, K; Okabe, M; Tajika, K; Takeuchi, J; Tamai, H; Wakita, S; Yamaguchi, H, 2006)
"Imatinib mesylate has been reported to produce positive results in atypical chronic myeloproliferative disorders (CMD) with chromosomal translocations that disrupt the platelet-derived growth factor receptor beta gene (PDGFRB)."3.72Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene. ( Bastie, JN; Castaigne, S; Cross, NC; Garcia, I; Mahon, FX; Terré, C, 2004)
"Eighty-three patients with various chronic myeloproliferative disorders [polycythemia vera (PV), essential thrombocytosis (ET), idiopathic myelofibrosis (IMF)] were analyzed for the occurrence of acute myeloid leukemia (AML) and myelodysplasia (MDS) during treatment with hydroxyurea (HU) alone or HU following treatment with busulphan (BU)."3.72Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. ( Hasselbalch, HC; Nielsen, I, 2003)
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."3.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
"A patient with idiopathic myelofibrosis is reported who developed a drug fever after treatment with hydroxyurea, a generally effective and well-tolerated drug in chronic myeloproliferative syndromes."3.69An unwanted side effect of hydroxyurea in a patient with idiopathic myelofibrosis. ( Fickers, MM; Pannebakker, MA; Starmans-Kool, MJ, 1995)
"We report four cases of cutaneous lower leg ulcers associated with hydroxyurea treatment for myeloproliferative disorders."3.68Hydroxyurea and lower leg ulcers. ( Margolis, DJ; Nguyen, TV, 1993)
"A case of idiopathic myelofibrosis (IMF) presenting with hypercalcemia and hypercalcitriolemia is reported."3.68Hypercalcemia in idiopathic myelofibrosis: modulation of calcium and collagen homeostasis by 1,25-dihydroxyvitamin D3. ( Hasselbalch, H; Junker, P; Schmidt, K; Voss, A, 1992)
" We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea."3.67The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes. ( Alter, BP; Gilbert, HS, 1985)
"In idiopathic myelofibrosis (IMF) PDGF is considered to be one of the growth factors responsible for the development of bone marrow fibrosis."2.71Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis. ( Birgens, H; Bjerrum, OW; Clausen, NT; Hansen, PB; Hasselbalch, HC; Jensen, BA; Ralfkiaer, E; Therkildsen, MH, 2003)
"Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms, respectively characterized by erythrocytosis and thrombocytosis."2.52Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2015)
"Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by sustained thrombocytosis, bone marrow megakaryocytic hyperplasia and an increased risk of thrombosis and hemorrhage."2.49[Treatment of essential thrombocythemia]. ( Alvarez-Larrán, A; Besses, C; Cervantes, F, 2013)
"Development of myelofibrosis in IMF is obviously due to disease progression unrelated to stage at diagnosis and not significantly influenced by treatment modalities."2.42Therapy-related changes of the bone marrow in chronic idiopathic myelofibrosis. ( Diehl, V; Hülsemann, R; Kvasnicka, HM; Schmitt-Gräff, A; Thiele, J, 2004)
"Median survival of patients with myelofibrosis with myeloid metaplasia (MMM) ranges from 3."2.41Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000. ( Cervantes, F, 2001)
"We report a case of myelofibrosis with myeloid metaplasia (MMM) that responded dramatically to oral busulfan treatment after failure of hydroxyurea."2.41Myelofibrosis: response to busulfan after hydroxyurea failure. ( Baumann, MA; Naqvi, T, 2002)
"Idiopathic myelofibrosis is the least common and carries the worst prognosis of the chronic myeloproliferative disorders."2.40Pathogenesis and management of idiopathic myelofibrosis. ( Reilly, JT, 1998)
"Idiopathic myelofibrosis is reviewed from several aspects."2.38Idiopathic myelofibrosis: historical review, diagnosis and management. ( Weinstein, IM, 1991)
"Primary myelofibrosis (PM) is one of the myeloproliferative neoplasm, where stem cell-derived clonal neoplasms was noticed."1.91Detection of primary myelofibrosis in blood serum via Raman spectroscopy assisted by machine learning approaches; correlation with clinical diagnosis. ( Aday, A; Bayrak, AG; Ceylan, Z; Depciuch, J; Guleken, Z; Hindilerden, İY; Jakubczyk, D; Jakubczyk, P; Kula-Maximenko, M; Nalçacı, M, 2023)
"Pruritus was reported by 49."1.91Differences between aquagenic and non-aquagenic pruritus in myeloproliferative neoplasms: An observational study of 500 patients. ( Ficheux, AS; Herbreteau, L; Ianotto, JC; Le Gall-Ianotto, C; Lippert, E; Misery, L; Pan-Petesch, B; Rio, L, 2023)
"Paediatric primary myelofibrosis (PMF) is exceedingly rare and distinct compared with adult PMF."1.91Complete resolution of primary myelofibrosis in an infant with steroids and hydroxyurea. ( Khera, S; Misra, P; Singh, K; Tripathi, P, 2023)
"Within the 1258 SMF of the MYSEC (MYelofibrosis SECondary to PV and ET) dataset, 135 (10."1.72Prediction of thrombosis in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study on 1258 patients. ( Albano, F; Arcaini, L; Auteri, G; Barbui, T; Benevolo, G; Bertù, L; Brociner, M; Caramazza, D; Caramella, M; Casetti, IC; Cattaneo, D; Cervantes, F; De Stefano, V; Della Porta, MG; Devos, T; Gotlib, J; Guglielmelli, P; Iurlo, A; Kiladjian, JJ; Komrokji, RS; Kuykendall, A; Maffioli, M; Merli, M; Mora, B; Palandri, F; Passamonti, F; Ross, DM; Rotunno, G; Ruggeri, M; Rumi, E; Salmoiraghi, S; Silver, RT; Vannucchi, AM, 2022)
"The pleural effusion was transudative, although there was no history of cardiac failure or hypoalbuminemia, and treatment with diuretics failed."1.62Transudative Pleural Effusion Associated with Extramedullary Hematopoiesis. ( Amaki, J; Aoki, T; Asano, K; Enokida, K; Hayama, N; Oguma, T; Okada, N; Takeuchi, T; Takihara, T; Tomomatsu, K, 2021)
"We report here 53 myelofibrosis patients that received a combination of hydroxyurea and ruxolitinib because of uncontrolled myeloproliferation."1.51Efficacy and safety of ruxolitinib and hydroxyurea combination in patients with hyperproliferative myelofibrosis. ( Benevolo, G; Binotto, G; Bonifacio, M; Breccia, M; Caocci, G; Cavo, M; De Stefano, V; Foà, R; Latagliata, R; Luciano, L; Martinelli, V; Martino, B; Palandri, F; Pane, F; Pugliese, N; Rossi, E; Scalzulli, E; Tiribelli, M, 2019)
"Cases (n = 647) were patients with second cancer (SC: carcinoma, non-melanoma skin cancer, hematological second cancer, and melanoma) and controls (n = 1234) were patients without SC, matched with cases for sex, age at MPN diagnosis, date of MPN diagnosis, and MPN disease duration."1.51Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study. ( Alvarez-Larran, A; Angona, A; Barbui, T; Beggiato, E; Benevolo, G; Bertolotti, L; Betti, S; Bonifacio, M; Cacciola, R; Carli, G; Carobbio, A; Casetti, IC; Cattaneo, D; De Stefano, V; Delaini, F; Di Veroli, A; Elli, EM; Erez, D; Finazzi, G; Fox, ML; Ghirardi, A; Gomez, M; Griesshammer, M; Guglielmelli, P; Iurlo, A; Lunghi, F; Marchetti, M; Masciulli, A; McMullin, MF; Palandri, F; Palova, M; Patriarca, A; Perez-Encinas, M; Recasens, V; Rumi, E; Scaffidi, L; Stephenson, C; Tieghi, A; Vannucchi, AM; Vianelli, N; Wille, K, 2019)
" The number of patients requiring ruxolitinib dosage reduction or discontinuations was lower during combination therapy and, at the end of follow-up the median ruxolitinib dose was increased in 50% of patients."1.51Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis. ( Annunziata, M; Casale, B; Cerchione, C; Crisà, E; Giordano, C; Grimaldi, F; Iovine, M; Luciano, L; Martinelli, V; Nappi, D; Pane, F; Pezzullo, L; Picardi, M; Pugliese, N; Villa, MR, 2019)
"Risk of thrombosis is higher in JAK2-mutated ET."1.51Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019)
"Myelofibrosis was treated with hydroxyurea."1.51Development of myelofibrosis and acute monocytic leukemia in a patient with hereditary spherocytosis: A case report. ( Liu, H; Qian, J; Shen, Q; Shi, WY; Yang, L; Yin, H; Zhang, YP, 2019)
"Polycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus, and risk of leukemic or fibrotic transformation."1.46Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management. ( Barbui, T; Tefferi, A, 2017)
"Hydroxyurea was the most commonly used cytoreductive therapy."1.46Multicenter Retrospective Analysis of Turkish Patients with Chronic Myeloproliferative Neoplasms. ( Bilgir, O; Çağlıyan, G; Çekdemir, D; Cömert, M; Haznedaroğlu, İC; İlhan, O; Kaya, E; Özdemirkıran, F; Şahin, F; Saydam, G; Soyer, N; Ünal, A; Vural, F; Yılmaz, M, 2017)
"We report a case of membranous nephropathy accompanied by kidney injury in a patient with primary myelofibrosis with additional features considered related to the patient's myeloproliferative disorder."1.46Membranous Nephropathy and Intrarenal Extramedullary Hematopoiesis in a Patient With Myelofibrosis. ( Aniort, J; Heng, AE; Kemeny, JL; Philipponnet, C; Ronco, P, 2017)
"Chronic inflammation is suggested to contribute to the Philadelphia-chromosome-negative myeloproliferative neoplasm (MPN) disease initiation and progression, as well as the development of premature atherosclerosis and may drive the development of other cancers in MPNs, both nonhematologic and hematologic."1.40Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms. ( Hasselbalch, HC, 2014)
"Diagnosis of post-PV myelofibrosis is established according to the International Working Group for Myeloproliferative Neoplasms Research and Treatment criteria."1.38How I treat polycythemia vera. ( Passamonti, F, 2012)
"A case of a 69-year-old woman with myelofibrosis presenting with non-small cell lung cancer was reported at Sotiria General Hospital in Athens."1.36Bevacizumab may be active in myelofibrosis. ( Dilana, K; Makrilia, N; Meletis, I; Nikolaidis, I; Stathopoulos, D; Syrigos, K; Xyla, V, 2010)
"The underlying cause was polycythemia rubra vera and osteomyolofibrosis."1.35[Budd-Chiari syndrome--from diagnosis to treatment--case reports]. ( Dybowska, D; Kozielewicz, D; Smukalska, E, 2008)
"Agnogenic myeloid metaplasia (AMM) is characterized by bone marrow fibrosis, splenomegaly and leukoerythroblastic anemia and is frequently accompanied by extramedullary hematopoiesis (EMH)."1.33Agnogenic myeloid metaplasia with pulmonary hematopoiesis. ( Boula, A; Foudoulakis, A; Mantadakis, E; Samonis, G; Xilouri, I, 2005)
"Granulocytic sarcoma is very rare in essential thrombocythemia, and this patient may be the first reported case of essential thrombocythemia that developed multiple lesions and a pathologic fracture without transformation to overt leukemia."1.33Multiple granulocytic sarcomas in essential thrombocythemia. ( Fujita, H; Kurata, M; Maeda, A; Matsushita, A; Mori, M; Nagai, K; Nagai, Y; Takahashi, T; Tanaka, K; Tanaka, Y; Togami, K, 2006)
"Hydroxyurea and myelosan were mostly used as cytostatic drugs while erythrocyte mass transfusions and hemoexfusions (phlebotomy)--for life-support."1.32[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases]. ( Pop, VP; Rukavitsyn, OA; Seriakov, AP, 2004)
"Controversial issues in chronic idiopathic myelofibrosis (IMP) are amongst others the evolution of the disease process and the influence of therapy on the dynamics of fibrosis."1.32Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients. ( Diehl, V; Kvasnicka, HM; Schmitt-Graeff, A; Thiele, J, 2003)
"Hydroxyurea (HU) is a good-controllable and well-tolerated cytostatic drug."1.32[Hydroxyurea-induced pneumonitis]. ( Schwonzen, M; Spangenberger, H; Spengler, M, 2003)
"A 60-year-old white woman with polycythemia rubra vera post splenectomy in November 2001 was found to have peripheral white blood cell counts increasing over 3 months."1.32Paraneoplastic eosinophilic fasciitis: a case report. ( Cohen, JJ; Jacob, SE; Kirsner, RS; Lodha, R; Romanelli, P, 2003)
"A 70-year-old man with primary myelofibrosis was treated with hydroxycarbamide and blood transfusions."1.31[Diagnostic image (117). A man with frequent blood transfusion and blister on his fingers. A form of porpheria cutanea tarda caused by excess iron]. ( Jonkhoff, AR; van der Valk, P; Zweegman, S, 2002)
"Of the 124 patients without myelofibrosis at onset, 42% later transformed into the myelofibrotic subtype."1.31Changing patterns of histological subgroups during therapy of Ph1+ chronic myelogenous leukaemia. ( Kvasnicka, HM; Leder, LD; Schaefer, HE; Schmitt-Graeff, A; Thiele, J, 2000)
"A case of idiopathic myelofibrosis presenting with a pleural effusion secondary to extramedullary haemopoeisis is described."1.30Pleural effusion secondary to extramedullary haemopoiesis in a patient with idiopathic myelofibrosis responding to pleurodesis and hydroxyurea. ( Burke, DK; Cryer, RJ; Jowitt, SN; Leggat, HM; Lewis, PS, 1997)
"We found a significant reduction of bone marrow fibrosis, believed to be mediated by suppression of thrombopoiesis by hydroxyurea."1.28Reversal of myelofibrosis by hydroxyurea. ( Löfvenberg, E; Ost, A; Roos, G; Wahlin, A, 1990)
"Seventeen patients with either chronic myelogenous leukemia (CML) or myelofibrosis with myeloid metaplasia (MMM) received 24 courses of splenic irradiation at this institution from 1973 to 1982."1.27Splenic irradiation in the treatment of patients with chronic myelogenous leukemia or myelofibrosis with myeloid metaplasia. Results of daily and intermittent fractionation with and without concomitant hydroxyurea. ( Desforges, J; Madoc-Jones, H; McKeough, PG; Wagner, H, 1986)
"A patient with postpolycythemic myeloid metaplasia who previously underwent splenectomy presented with recurrent, protracted gastrointestinal tract hemorrhage."1.27Small intestinal myeloid metaplasia. ( Alroy, G; Ben-Arieh, Y; Brenner, B; Jacobs, R; Schreibman, D; Tatarsky, I, 1988)
"Treatment with hydroxyurea was followed by a dramatic response of both the polycythemia vera and the HES, with return to normal of the abnormal immunologic measures."1.27Hypereosinophilic syndrome associated with polycythemia vera. ( Berrebi, A; Varon, D; Wetzler, M, 1986)
"Treatment with hydroxyurea was followed by a marked reduction in spleen size, a decrease in white cell count and healing of the skin lesions."1.26Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case. ( Atamer, MA; Friedhoff, FW; Thelmo, WL, 1978)
"Hydroxyurea is an effective agent in the treatment of chronic myelogenous leukemia."1.25Skin changes secondary to hydroxyurea therapy. ( Goltz, RW; Kennedy, BJ; Smith, LR, 1975)

Research

Studies (140)

TimeframeStudies, this research(%)All Research%
pre-199013 (9.29)18.7374
1990's21 (15.00)18.2507
2000's44 (31.43)29.6817
2010's47 (33.57)24.3611
2020's15 (10.71)2.80

Authors

AuthorsStudies
Sekhri, R1
Sadjadian, P1
Becker, T1
Kolatzki, V1
Huenerbein, K1
Meixner, R1
Marchi, H1
Wallmann, R1
Fuchs, C1
Griesshammer, M3
Wille, K2
Gerds, AT2
Lyons, RM1
Colucci, P1
Kalafut, P1
Paranagama, D1
Verstovsek, S2
Alvarez-Larrán, A4
Garrote, M1
Ferrer-Marín, F1
Pérez-Encinas, M2
Mata-Vazquez, MI1
Bellosillo, B1
Arellano-Rodrigo, E3
Gómez, M2
García, R1
García-Gutiérrez, V1
Gasior, M1
Cuevas, B1
Angona, A2
Gómez-Casares, MT1
Martínez, CM1
Magro, E1
Ayala, R1
Del Orbe-Barreto, R1
Pérez-López, R1
Fox, ML2
Raya, JM1
Guerrero, L1
García-Hernández, C1
Caballero, G1
Murillo, I1
Xicoy, B1
Ramírez, MJ1
Carreño-Tarragona, G1
Hernández-Boluda, JC1
Pereira, A1
Mora, B3
Guglielmelli, P4
Kuykendall, A1
Rumi, E2
Maffioli, M3
Palandri, F3
De Stefano, V4
Caramella, M1
Salmoiraghi, S2
Kiladjian, JJ1
Gotlib, J2
Iurlo, A2
Cervantes, F5
Ruggeri, M1
Silver, RT1
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Benevolo, G3
Ross, DM1
Della Porta, MG1
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Cavo, M1
Besses, C1
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Spatola, T1
Sivera, P1
Ricca, I1
Tarella, C1
Rambaldi, A1
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Croci, G1
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Boveri, E1
Fu, R1
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Yang, R1
Tiziana Storlazzi, C1
Pieri, L1
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Lasho, T1
de Unamuno-Bustos, B1
Ballester-Sánchez, R1
Sabater Marco, V1
Vilata-Corell, JJ1
Shimoda, K2
Takenaka, K2
Kitanaka, A1
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Matthews, AG1
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Hansen, M1
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Bjerrum, OW3
Straten, PT2
Svane, IM2
Jensen, MK2
Hultcrantz, M1
Derolf, ÅR1
Stein, BL2
Moliterno, AR1
Tiu, RV1
Yoshimoto, G1
Miyamoto, T1
Shirane, S1
Araki, M1
Morishita, S1
Edahiro, Y1
Sunami, Y1
Hironaka, Y1
Noguchi, M1
Koike, M1
Sato, E1
Ohsaka, A1
Komatsu, N1
Arcasoy, M1
Nguyen, MH1
Shah, N1
Moliterno, A1
Jamieson, C1
Pollyea, DA1
Scott, B1
Wadleigh, M1
Levine, R1
Komrokji, R1
Klisovic, R1
Gundabolu, K1
Kropf, P1
Wetzler, M2
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Ribeiro, R1
Paschal, R1
Mohan, S1
Podoltsev, N1
Prchal, J1
Talpaz, M1
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Mesa, RA2
Aylı, M1
Özcan, M1
Cengiz Seval, G1
Nazha, A1
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Haznedaroğlu, İC1
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Yılmaz, M1
Ünal, A1
Çağlıyan, G1
Bilgir, O1
İlhan, O1
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Kaya, E1
Şahin, F1
Vural, F1
Saydam, G1
Lim, Y1
Uchida, N1
Shimomura, T1
Nagafuji, K1
Kondo, T1
Shibayama, H1
Mori, T1
Usuki, K1
Azuma, T1
Tsutsumi, Y1
Tanaka, J1
Dairaku, H1
Matsuo, K1
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Kurokawa, M1
Arai, S1
Peluso, I1
Pareto, AE1
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Barth, P1
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Wheatley, K3
Harrison, CN4
Green, AR4
Lukina, EA1
Sysoeva, EP1
Kitsenko, EA1
Varlamova, EIu1
Inozemtseva, MV1
Semenova, EA2
Nadinskaia, MIu1
Ivashkin, VT1
Barosi, G2
Birgegard, G1
Harrison, C2
Hasselbalch, H3
Kiladijan, JJ1
Lengfelder, E1
Mesa, R1
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Manakova, TE1
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Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Longitudinal, Non-Interventional Study of Disease Burden and Treatment of Patients With Low-Risk Myelofibrosis (MF) or High-Risk Essential Thrombocythemia (ET) or ET Patients Receiving ET-Directed Therapy[NCT02953704]1,469 participants (Actual)Observational2016-12-31Completed
French Aspirin Study in Essential Thrombocythemia: an Open and Randomized Study[NCT02611973]Phase 32,250 participants (Anticipated)Interventional2016-03-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

29 reviews available for hydroxyurea and Primary Myelofibrosis

ArticleYear
SOHO State of the Art Updates and Next Questions | Polycythemia Vera: Is It Time to Rethink Treatment?
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:2

    Topics: Aspirin; Humans; Hydroxyurea; Janus Kinase 2; Middle Aged; Polycythemia Vera; Primary Myelofibrosis;

2023
SOHO State of the Art Updates and Next Questions | Polycythemia Vera: Is It Time to Rethink Treatment?
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:2

    Topics: Aspirin; Humans; Hydroxyurea; Janus Kinase 2; Middle Aged; Polycythemia Vera; Primary Myelofibrosis;

2023
Polycythemia vera: from new, modified diagnostic criteria to new therapeutic approaches.
    Clinical advances in hematology & oncology : H&O, 2017, Volume: 15, Issue:9

    Topics: Age Factors; Calreticulin; Female; Hematocrit; Humans; Hydroxyurea; Interferons; Janus Kinase 2; Mal

2017
Polycythemia vera: from new, modified diagnostic criteria to new therapeutic approaches.
    Clinical advances in hematology & oncology : H&O, 2017, Volume: 15, Issue:9

    Topics: Age Factors; Calreticulin; Female; Hematocrit; Humans; Hydroxyurea; Interferons; Janus Kinase 2; Mal

2017
Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature.
    Internal medicine (Tokyo, Japan), 2018, May-01, Volume: 57, Issue:9

    Topics: Aged; Fatal Outcome; Humans; Hydroxyurea; Male; Prednisolone; Primary Myelofibrosis; Pyrazoles; Tube

2018
Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature.
    Internal medicine (Tokyo, Japan), 2018, May-01, Volume: 57, Issue:9

    Topics: Aged; Fatal Outcome; Humans; Hydroxyurea; Male; Prednisolone; Primary Myelofibrosis; Pyrazoles; Tube

2018
Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis.
    Haematologica, 2019, Volume: 104, Issue:12

    Topics: Hemorrhage; Humans; Hydroxyurea; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Risk Factors;

2019
Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis.
    Haematologica, 2019, Volume: 104, Issue:12

    Topics: Hemorrhage; Humans; Hydroxyurea; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Risk Factors;

2019
[Treatment of essential thrombocythemia].
    Medicina clinica, 2013, Sep-21, Volume: 141, Issue:6

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progress

2013
[Treatment of essential thrombocythemia].
    Medicina clinica, 2013, Sep-21, Volume: 141, Issue:6

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progress

2013
Paediatric essential thrombocythaemia: clinical and molecular features, diagnosis and treatment.
    British journal of haematology, 2013, Volume: 163, Issue:3

    Topics: Adolescent; Age of Onset; Anticoagulants; Child; Child, Preschool; Clone Cells; Disease Progression;

2013
Paediatric essential thrombocythaemia: clinical and molecular features, diagnosis and treatment.
    British journal of haematology, 2013, Volume: 163, Issue:3

    Topics: Adolescent; Age of Onset; Anticoagulants; Child; Child, Preschool; Clone Cells; Disease Progression;

2013
[Clinical aspects of primary myelofibrosis in Japan].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:3

    Topics: Blood Cell Count; Danazol; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Japan; Meth

2014
[Clinical aspects of primary myelofibrosis in Japan].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:3

    Topics: Blood Cell Count; Danazol; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Japan; Meth

2014
Leukemic transformation in myeloproliferative neoplasms: therapy-related or unrelated?
    Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Disease Progression; Humans; Hydroxyurea; Ja

2014
Leukemic transformation in myeloproliferative neoplasms: therapy-related or unrelated?
    Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Disease Progression; Humans; Hydroxyurea; Ja

2014
Polycythemia vera disease burden: contributing factors, impact on quality of life, and emerging treatment options.
    Annals of hematology, 2014, Volume: 93, Issue:12

    Topics: Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cost of Illness; Disease Progression

2014
Polycythemia vera disease burden: contributing factors, impact on quality of life, and emerging treatment options.
    Annals of hematology, 2014, Volume: 93, Issue:12

    Topics: Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cost of Illness; Disease Progression

2014
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy,

2014
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy,

2014
Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Disease Management; Humans; Hydroxyurea; Janus Kinas

2015
Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Disease Management; Humans; Hydroxyurea; Janus Kinas

2015
Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2015, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Calreticulin; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; J

2015
Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2015, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Calreticulin; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; J

2015
Where to Turn for Second-Line Cytoreduction After Hydroxyurea in Polycythemia Vera?
    The oncologist, 2016, Volume: 21, Issue:4

    Topics: Busulfan; Cell Proliferation; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myeloid, Acute; Nitrile

2016
Where to Turn for Second-Line Cytoreduction After Hydroxyurea in Polycythemia Vera?
    The oncologist, 2016, Volume: 21, Issue:4

    Topics: Busulfan; Cell Proliferation; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myeloid, Acute; Nitrile

2016
A unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera and primary myelofibrosis: results of a European LeukemiaNet (ELN) consensus process.
    British journal of haematology, 2010, Volume: 148, Issue:6

    Topics: Antineoplastic Agents; Consensus Development Conferences as Topic; Drug Resistance; Humans; Hydroxyu

2010
A unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera and primary myelofibrosis: results of a European LeukemiaNet (ELN) consensus process.
    British journal of haematology, 2010, Volume: 148, Issue:6

    Topics: Antineoplastic Agents; Consensus Development Conferences as Topic; Drug Resistance; Humans; Hydroxyu

2010
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyu

2009
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyu

2009
Do we know more about essential thrombocythemia because of JAK2V617F?
    Current hematologic malignancy reports, 2009, Volume: 4, Issue:1

    Topics: Female; Humans; Hydroxyurea; Janus Kinase 2; Polycythemia Vera; Pregnancy; Pregnancy Complications;

2009
Do we know more about essential thrombocythemia because of JAK2V617F?
    Current hematologic malignancy reports, 2009, Volume: 4, Issue:1

    Topics: Female; Humans; Hydroxyurea; Janus Kinase 2; Polycythemia Vera; Pregnancy; Pregnancy Complications;

2009
Hydroxyurea induced dermatomyositis-like eruption.
    The Australasian journal of dermatology, 2012, Volume: 53, Issue:3

    Topics: Aged; Anemia, Megaloblastic; Antineoplastic Agents; Dermatomyositis; Drug Eruptions; Female; Humans;

2012
Hydroxyurea induced dermatomyositis-like eruption.
    The Australasian journal of dermatology, 2012, Volume: 53, Issue:3

    Topics: Aged; Anemia, Megaloblastic; Antineoplastic Agents; Dermatomyositis; Drug Eruptions; Female; Humans;

2012
[True polycythemia: current views of pathogenesis, diagnostics and treatment].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Age Factors; Algorithms; Antineoplastic Agents; Aspirin; Benzamides; Combined Modality Therapy; Hema

2012
[True polycythemia: current views of pathogenesis, diagnostics and treatment].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Age Factors; Algorithms; Antineoplastic Agents; Aspirin; Benzamides; Combined Modality Therapy; Hema

2012
Therapy-related changes of the bone marrow in chronic idiopathic myelofibrosis.
    Histology and histopathology, 2004, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Bone Marrow; Busulfan; Ch

2004
Therapy-related changes of the bone marrow in chronic idiopathic myelofibrosis.
    Histology and histopathology, 2004, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Bone Marrow; Busulfan; Ch

2004
Myelofibrosis: biology and treatment options.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Benzamides; Chronic Disease; Darbepoetin alfa; Erythropoietin; Hematopoietic Stem Cell Transplantati

2007
Myelofibrosis: biology and treatment options.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Benzamides; Chronic Disease; Darbepoetin alfa; Erythropoietin; Hematopoietic Stem Cell Transplantati

2007
The management of elderly patients with myeloproliferative disorders.
    Hematological oncology, 1993, Volume: 11 Suppl 1

    Topics: Adult; Age Factors; Aged; Bone Marrow Transplantation; Busulfan; Chronic Disease; Humans; Hydroxyure

1993
The management of elderly patients with myeloproliferative disorders.
    Hematological oncology, 1993, Volume: 11 Suppl 1

    Topics: Adult; Age Factors; Aged; Bone Marrow Transplantation; Busulfan; Chronic Disease; Humans; Hydroxyure

1993
Ectopic medullary hematopoiesis as a cause of ascites in agnogenic myeloid metaplasia. Case report and review of the literature.
    Acta haematologica, 1993, Volume: 89, Issue:2

    Topics: Anemia, Hemolytic; Ascites; Biopsy; Bone Marrow; Busulfan; Combined Modality Therapy; Coombs Test; D

1993
Ectopic medullary hematopoiesis as a cause of ascites in agnogenic myeloid metaplasia. Case report and review of the literature.
    Acta haematologica, 1993, Volume: 89, Issue:2

    Topics: Anemia, Hemolytic; Ascites; Biopsy; Bone Marrow; Busulfan; Combined Modality Therapy; Coombs Test; D

1993
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Pathogenesis and management of idiopathic myelofibrosis.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cladribine; Combined Modality Therapy; Di

1998
Pathogenesis and management of idiopathic myelofibrosis.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cladribine; Combined Modality Therapy; Di

1998
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998
Myelofibrosis with myeloid metaplasia.
    The New England journal of medicine, 2000, Apr-27, Volume: 342, Issue:17

    Topics: Antineoplastic Agents; Bone Marrow; Diagnosis, Differential; Hematopoietic Stem Cell Transplantation

2000
Myelofibrosis with myeloid metaplasia.
    The New England journal of medicine, 2000, Apr-27, Volume: 342, Issue:17

    Topics: Antineoplastic Agents; Bone Marrow; Diagnosis, Differential; Hematopoietic Stem Cell Transplantation

2000
Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aged; Anemia; Aneuploidy; Angiogenesis Inhibitors; Bone Marrow Transplantation; Case Management; Com

2001
Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aged; Anemia; Aneuploidy; Angiogenesis Inhibitors; Bone Marrow Transplantation; Case Management; Com

2001
Myelofibrosis: response to busulfan after hydroxyurea failure.
    International journal of clinical practice, 2002, Volume: 56, Issue:4

    Topics: Alkylating Agents; Antimetabolites; Busulfan; Gastrointestinal Hemorrhage; Humans; Hydroxyurea; Male

2002
Myelofibrosis: response to busulfan after hydroxyurea failure.
    International journal of clinical practice, 2002, Volume: 56, Issue:4

    Topics: Alkylating Agents; Antimetabolites; Busulfan; Gastrointestinal Hemorrhage; Humans; Hydroxyurea; Male

2002
Idiopathic myelofibrosis: historical review, diagnosis and management.
    Blood reviews, 1991, Volume: 5, Issue:2

    Topics: Anemia; Bone Marrow; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Diagnosis, Di

1991
Idiopathic myelofibrosis: historical review, diagnosis and management.
    Blood reviews, 1991, Volume: 5, Issue:2

    Topics: Anemia; Bone Marrow; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Diagnosis, Di

1991

Trials

11 trials available for hydroxyurea and Primary Myelofibrosis

ArticleYear
Survival outcomes in myelofibrosis patients treated with ruxolitinib: A population-based cohort study in Sweden and Norway.
    European journal of haematology, 2019, Volume: 103, Issue:6

    Topics: Aged; Busulfan; Danazol; Disease-Free Survival; Female; Follow-Up Studies; Glucocorticoids; Humans;

2019
Survival outcomes in myelofibrosis patients treated with ruxolitinib: A population-based cohort study in Sweden and Norway.
    European journal of haematology, 2019, Volume: 103, Issue:6

    Topics: Aged; Busulfan; Danazol; Disease-Free Survival; Female; Follow-Up Studies; Glucocorticoids; Humans;

2019
Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
    European journal of haematology, 2021, Volume: 107, Issue:6

    Topics: Aged; Alleles; Antineoplastic Agents; Blood Cell Count; Cohort Studies; Female; Humans; Hydroxyurea;

2021
Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
    European journal of haematology, 2021, Volume: 107, Issue:6

    Topics: Aged; Alleles; Antineoplastic Agents; Blood Cell Count; Cohort Studies; Female; Humans; Hydroxyurea;

2021
Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-20, Volume: 27, Issue:18

    Topics: Biomarkers; Bone Marrow; Hemoglobins; Hemorrhage; Humans; Hydroxyurea; Leukocyte Count; Platelet Agg

2009
Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-20, Volume: 27, Issue:18

    Topics: Biomarkers; Bone Marrow; Hemoglobins; Hemorrhage; Humans; Hydroxyurea; Leukocyte Count; Platelet Agg

2009
Impact of bone marrow morphology on multivariate risk classification in chronic myelogenous leukemia.
    Acta haematologica, 2003, Volume: 109, Issue:1

    Topics: Bone Marrow; Erythroid Precursor Cells; Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-

2003
Impact of bone marrow morphology on multivariate risk classification in chronic myelogenous leukemia.
    Acta haematologica, 2003, Volume: 109, Issue:1

    Topics: Bone Marrow; Erythroid Precursor Cells; Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-

2003
Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis.
    American journal of hematology, 2003, Volume: 74, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Female;

2003
Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis.
    American journal of hematology, 2003, Volume: 74, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Female;

2003
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Female; F

2005
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Female; F

2005
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
    Blood, 2008, Jan-01, Volume: 111, Issue:1

    Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematolo

2008
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
    Blood, 2008, Jan-01, Volume: 111, Issue:1

    Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematolo

2008
[Treatment of polycythemia with 32P with or without hydroxyurea maintenance therapy. Preliminary results in 237 elderly and high vascular risk subjects studied since 1980].
    Presse medicale (Paris, France : 1983), 1993, Dec-11, Volume: 22, Issue:39

    Topics: Age Factors; Aged; Carcinoma; Cardiovascular Diseases; Female; Humans; Hydroxyurea; Injections, Intr

1993
[Treatment of polycythemia with 32P with or without hydroxyurea maintenance therapy. Preliminary results in 237 elderly and high vascular risk subjects studied since 1980].
    Presse medicale (Paris, France : 1983), 1993, Dec-11, Volume: 22, Issue:39

    Topics: Age Factors; Aged; Carcinoma; Cardiovascular Diseases; Female; Humans; Hydroxyurea; Injections, Intr

1993
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Treatment of polycythemia vera: use of 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age. The French Polycythemia Study Group.
    Blood, 1997, Apr-01, Volume: 89, Issue:7

    Topics: Actuarial Analysis; Aged; Alkylating Agents; Combined Modality Therapy; Disease Progression; Follow-

1997
Treatment of polycythemia vera: use of 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age. The French Polycythemia Study Group.
    Blood, 1997, Apr-01, Volume: 89, Issue:7

    Topics: Actuarial Analysis; Aged; Alkylating Agents; Combined Modality Therapy; Disease Progression; Follow-

1997
Bone marrow features improve prognostic efficiency in multivariate risk classification of chronic-phase Ph(1+) chronic myelogenous leukemia: a multicenter trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jun-15, Volume: 19, Issue:12

    Topics: Antineoplastic Agents; Bone Marrow; Decision Trees; Female; Humans; Hydroxyurea; Interferon alpha-2;

2001
Bone marrow features improve prognostic efficiency in multivariate risk classification of chronic-phase Ph(1+) chronic myelogenous leukemia: a multicenter trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jun-15, Volume: 19, Issue:12

    Topics: Antineoplastic Agents; Bone Marrow; Decision Trees; Female; Humans; Hydroxyurea; Interferon alpha-2;

2001

Other Studies

101 other studies available for hydroxyurea and Primary Myelofibrosis

ArticleYear
Ruxolitinib-treated polycythemia vera patients and their risk of secondary malignancies.
    Annals of hematology, 2021, Volume: 100, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Hydroxyurea; Incidence; Janus Kin

2021
Ruxolitinib-treated polycythemia vera patients and their risk of secondary malignancies.
    Annals of hematology, 2021, Volume: 100, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Hydroxyurea; Incidence; Janus Kin

2021
Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Myelofibrosis Enrolled in the MOST Study.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:7

    Topics: Aged; Cohort Studies; Humans; Hydroxyurea; Primary Myelofibrosis; Prospective Studies; Thrombocythem

2022
Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Myelofibrosis Enrolled in the MOST Study.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:7

    Topics: Aged; Cohort Studies; Humans; Hydroxyurea; Primary Myelofibrosis; Prospective Studies; Thrombocythem

2022
Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea.
    Cancer, 2022, 07-01, Volume: 128, Issue:13

    Topics: Hemorrhage; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Nitriles; Poly

2022
Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea.
    Cancer, 2022, 07-01, Volume: 128, Issue:13

    Topics: Hemorrhage; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Nitriles; Poly

2022
Prediction of thrombosis in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study on 1258 patients.
    Leukemia, 2022, Volume: 36, Issue:10

    Topics: Humans; Hydroxyurea; Janus Kinase Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Thrombocythe

2022
Prediction of thrombosis in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study on 1258 patients.
    Leukemia, 2022, Volume: 36, Issue:10

    Topics: Humans; Hydroxyurea; Janus Kinase Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Thrombocythe

2022
Differences between aquagenic and non-aquagenic pruritus in myeloproliferative neoplasms: An observational study of 500 patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2023, Volume: 37, Issue:6

    Topics: Humans; Hydroxyurea; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Pruritu

2023
Differences between aquagenic and non-aquagenic pruritus in myeloproliferative neoplasms: An observational study of 500 patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2023, Volume: 37, Issue:6

    Topics: Humans; Hydroxyurea; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Pruritu

2023
Detection of primary myelofibrosis in blood serum via Raman spectroscopy assisted by machine learning approaches; correlation with clinical diagnosis.
    Nanomedicine : nanotechnology, biology, and medicine, 2023, Volume: 53

    Topics: Biomarkers; Humans; Hydroxyurea; Polycythemia Vera; Primary Myelofibrosis; Serum; Spectrum Analysis,

2023
Detection of primary myelofibrosis in blood serum via Raman spectroscopy assisted by machine learning approaches; correlation with clinical diagnosis.
    Nanomedicine : nanotechnology, biology, and medicine, 2023, Volume: 53

    Topics: Biomarkers; Humans; Hydroxyurea; Polycythemia Vera; Primary Myelofibrosis; Serum; Spectrum Analysis,

2023
Moving toward disease modification in polycythemia vera.
    Blood, 2023, Nov-30, Volume: 142, Issue:22

    Topics: Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Leukemia, Myeloid, Acute; Polycythemia Vera;

2023
Moving toward disease modification in polycythemia vera.
    Blood, 2023, Nov-30, Volume: 142, Issue:22

    Topics: Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Leukemia, Myeloid, Acute; Polycythemia Vera;

2023
Complete resolution of primary myelofibrosis in an infant with steroids and hydroxyurea.
    BMJ case reports, 2023, Nov-22, Volume: 16, Issue:11

    Topics: Humans; Hydroxyurea; Infant; Primary Myelofibrosis; Remission, Spontaneous; Steroids; Thrombocytopen

2023
Complete resolution of primary myelofibrosis in an infant with steroids and hydroxyurea.
    BMJ case reports, 2023, Nov-22, Volume: 16, Issue:11

    Topics: Humans; Hydroxyurea; Infant; Primary Myelofibrosis; Remission, Spontaneous; Steroids; Thrombocytopen

2023
Hydroxyurea-induced Tooth Discoloration
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020, Feb-20, Volume: 37, Issue:1

    Topics: Aged, 80 and over; Antineoplastic Agents; Humans; Hydroxyurea; Male; Primary Myelofibrosis; Tooth Di

2020
Hydroxyurea-induced Tooth Discoloration
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020, Feb-20, Volume: 37, Issue:1

    Topics: Aged, 80 and over; Antineoplastic Agents; Humans; Hydroxyurea; Male; Primary Myelofibrosis; Tooth Di

2020
Development of myelofibrosis and acute monocytic leukemia in a patient with hereditary spherocytosis: A case report.
    Medicine, 2019, Volume: 98, Issue:50

    Topics: Biopsy; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Monocytic, Acute; Male; Middle Aged; Prima

2019
Development of myelofibrosis and acute monocytic leukemia in a patient with hereditary spherocytosis: A case report.
    Medicine, 2019, Volume: 98, Issue:50

    Topics: Biopsy; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Monocytic, Acute; Male; Middle Aged; Prima

2019
Transudative Pleural Effusion Associated with Extramedullary Hematopoiesis.
    Internal medicine (Tokyo, Japan), 2021, Feb-01, Volume: 60, Issue:3

    Topics: Aged; Hematologic Diseases; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Pleural Effusi

2021
Transudative Pleural Effusion Associated with Extramedullary Hematopoiesis.
    Internal medicine (Tokyo, Japan), 2021, Feb-01, Volume: 60, Issue:3

    Topics: Aged; Hematologic Diseases; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Pleural Effusi

2021
Lenalidomide: A double-edged sword for concomitant multiple myeloma and post-essential thrombocythemia myelofibrosis.
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Calreticulin; Dexamethas

2021
Lenalidomide: A double-edged sword for concomitant multiple myeloma and post-essential thrombocythemia myelofibrosis.
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Calreticulin; Dexamethas

2021
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
    Annals of hematology, 2021, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Aspirin; Child; Female; Fibrinolytic Agents; Follow-Up Stu

2021
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
    Annals of hematology, 2021, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Aspirin; Child; Female; Fibrinolytic Agents; Follow-Up Stu

2021
IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia.
    Frontiers of medicine, 2022, Volume: 16, Issue:3

    Topics: Biomarkers; Humans; Hydroxyurea; Interferon Regulatory Factors; Janus Kinase 2; Leukemia, Myeloid, A

2022
IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia.
    Frontiers of medicine, 2022, Volume: 16, Issue:3

    Topics: Biomarkers; Humans; Hydroxyurea; Interferon Regulatory Factors; Janus Kinase 2; Leukemia, Myeloid, A

2022
Occult hepatitis B infection reactivation after ruxolitinib therapy.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:6

    Topics: Aged; Antiviral Agents; Drug Resistance; Enzyme Inhibitors; Guanine; Hepatitis B, Chronic; Humans; H

2017
Occult hepatitis B infection reactivation after ruxolitinib therapy.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:6

    Topics: Aged; Antiviral Agents; Drug Resistance; Enzyme Inhibitors; Guanine; Hepatitis B, Chronic; Humans; H

2017
Cardiac tamponade in myelofibrosis: A Mayo clinic series of nine consecutive cases.
    American journal of hematology, 2017, Volume: 92, Issue:9

    Topics: Aged; Aged, 80 and over; Cardiac Tamponade; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyur

2017
Cardiac tamponade in myelofibrosis: A Mayo clinic series of nine consecutive cases.
    American journal of hematology, 2017, Volume: 92, Issue:9

    Topics: Aged; Aged, 80 and over; Cardiac Tamponade; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyur

2017
Membranous Nephropathy and Intrarenal Extramedullary Hematopoiesis in a Patient With Myelofibrosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:6

    Topics: Acute Kidney Injury; Antineoplastic Agents; Edema; Glomerulonephritis, Membranous; Hematopoiesis, Ex

2017
Membranous Nephropathy and Intrarenal Extramedullary Hematopoiesis in a Patient With Myelofibrosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:6

    Topics: Acute Kidney Injury; Antineoplastic Agents; Edema; Glomerulonephritis, Membranous; Hematopoiesis, Ex

2017
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Mutation landscape in patients with myelofibrosis receiving ruxolitinib or hydroxyurea.
    Blood cancer journal, 2018, 11-22, Volume: 8, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; DNA Mutational Analysis; Female; Follow-Up Studies; Huma

2018
Mutation landscape in patients with myelofibrosis receiving ruxolitinib or hydroxyurea.
    Blood cancer journal, 2018, 11-22, Volume: 8, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; DNA Mutational Analysis; Female; Follow-Up Studies; Huma

2018
Hypersegmentation of Granulocytes and Monocytes in a Patient with Primary Myelofibrosis Treated with Hydroxycarbamide
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2019, May-03, Volume: 36, Issue:2

    Topics: Granulocytes; Humans; Hydroxyurea; Male; Middle Aged; Monocytes; Primary Myelofibrosis

2019
Hypersegmentation of Granulocytes and Monocytes in a Patient with Primary Myelofibrosis Treated with Hydroxycarbamide
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2019, May-03, Volume: 36, Issue:2

    Topics: Granulocytes; Humans; Hydroxyurea; Male; Middle Aged; Monocytes; Primary Myelofibrosis

2019
Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis.
    Cancer medicine, 2019, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers; Drug Therapy, Combination; Female

2019
Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis.
    Cancer medicine, 2019, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers; Drug Therapy, Combination; Female

2019
Treatment of Philadelphia-negative myeloproliferative neoplasms in accelerated/blastic phase with azacytidine. Clinical results and identification of prognostic factors.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Female; Humans; Hydroxyurea; Leuke

2019
Treatment of Philadelphia-negative myeloproliferative neoplasms in accelerated/blastic phase with azacytidine. Clinical results and identification of prognostic factors.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Female; Humans; Hydroxyurea; Leuke

2019
Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study.
    Leukemia, 2019, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Case-Control Studies; Humans; Hydroxyurea; Neoplasms, Second Primary; Nitrile

2019
Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study.
    Leukemia, 2019, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Case-Control Studies; Humans; Hydroxyurea; Neoplasms, Second Primary; Nitrile

2019
Efficacy and safety of ruxolitinib and hydroxyurea combination in patients with hyperproliferative myelofibrosis.
    Annals of hematology, 2019, Volume: 98, Issue:8

    Topics: Aged; Aged, 80 and over; Blood Platelets; Cell Count; Cell Proliferation; Drug Administration Schedu

2019
Efficacy and safety of ruxolitinib and hydroxyurea combination in patients with hyperproliferative myelofibrosis.
    Annals of hematology, 2019, Volume: 98, Issue:8

    Topics: Aged; Aged, 80 and over; Blood Platelets; Cell Count; Cell Proliferation; Drug Administration Schedu

2019
Telomere shortening in Ph-negative chronic myeloproliferative neoplasms: a biological marker of polycythemia vera and myelofibrosis, regardless of hydroxycarbamide therapy.
    Experimental hematology, 2013, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Clone Cells; Female

2013
Telomere shortening in Ph-negative chronic myeloproliferative neoplasms: a biological marker of polycythemia vera and myelofibrosis, regardless of hydroxycarbamide therapy.
    Experimental hematology, 2013, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Clone Cells; Female

2013
Cutaneous involvement by post-polycythemia vera myelofibrosis.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Aged; Aspirin; Biopsy; Cell Lineage; Disease Progression; Drug Therapy, Combination; Fibrosis; Hemat

2014
Cutaneous involvement by post-polycythemia vera myelofibrosis.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Aged; Aspirin; Biopsy; Cell Lineage; Disease Progression; Drug Therapy, Combination; Fibrosis; Hemat

2014
Complex karyotype in a polycythemia vera patient with a novel SETD1B/GTF2H3 fusion gene.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Chromosome Deletion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 6; Combined Modality Ther

2014
Complex karyotype in a polycythemia vera patient with a novel SETD1B/GTF2H3 fusion gene.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Chromosome Deletion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 6; Combined Modality Ther

2014
Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms.
    Expert review of hematology, 2014, Volume: 7, Issue:2

    Topics: Chronic Disease; Comorbidity; Humans; Hydroxyurea; Inflammation; Interferon alpha-2; Interferon-alph

2014
Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms.
    Expert review of hematology, 2014, Volume: 7, Issue:2

    Topics: Chronic Disease; Comorbidity; Humans; Hydroxyurea; Inflammation; Interferon alpha-2; Interferon-alph

2014
Dermatomyositis-like eruption associated with hydroxyurea therapy: a premalignant condition?
    Actas dermo-sifiliograficas, 2014, Volume: 105, Issue:9

    Topics: Aged; Dermatomyositis; Diagnosis, Differential; Drug Eruptions; Drug Substitution; Erythema; Female;

2014
Dermatomyositis-like eruption associated with hydroxyurea therapy: a premalignant condition?
    Actas dermo-sifiliograficas, 2014, Volume: 105, Issue:9

    Topics: Aged; Dermatomyositis; Diagnosis, Differential; Drug Eruptions; Drug Substitution; Erythema; Female;

2014
Hydroxycarbamide-induced cutaneous ulceration with a difference.
    The British journal of dermatology, 2014, Volume: 171, Issue:6

    Topics: Diagnosis, Differential; Drug Eruptions; Female; Hematinics; Humans; Hydroxyurea; Middle Aged; Prima

2014
Hydroxycarbamide-induced cutaneous ulceration with a difference.
    The British journal of dermatology, 2014, Volume: 171, Issue:6

    Topics: Diagnosis, Differential; Drug Eruptions; Female; Hematinics; Humans; Hydroxyurea; Middle Aged; Prima

2014
Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α.
    European journal of haematology, 2015, Volume: 94, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Case-Control Studies; CD56 Antigen; Female; G

2015
Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α.
    European journal of haematology, 2015, Volume: 94, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Case-Control Studies; CD56 Antigen; Female; G

2015
Consequences of the JAK2V617F allele burden for the prediction of transformation into myelofibrosis from polycythemia vera and essential thrombocythemia.
    International journal of hematology, 2015, Volume: 101, Issue:2

    Topics: Alleles; Bone Marrow; Disease Progression; Humans; Hydroxyurea; Janus Kinase 2; Mutation; Polycythem

2015
Consequences of the JAK2V617F allele burden for the prediction of transformation into myelofibrosis from polycythemia vera and essential thrombocythemia.
    International journal of hematology, 2015, Volume: 101, Issue:2

    Topics: Alleles; Bone Marrow; Disease Progression; Humans; Hydroxyurea; Janus Kinase 2; Mutation; Polycythem

2015
Ruxolitinib Treatment in a Patient with Primary Myelofibrosis Resistant to Conventional Therapies and Splenectomy: A Case Report.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:2

    Topics: Aged; Aspergillosis; Blood Transfusion; Danazol; Disease Progression; Drug Resistance; Fatal Outcome

2015
Ruxolitinib Treatment in a Patient with Primary Myelofibrosis Resistant to Conventional Therapies and Splenectomy: A Case Report.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:2

    Topics: Aged; Aspergillosis; Blood Transfusion; Danazol; Disease Progression; Drug Resistance; Fatal Outcome

2015
Multicenter Retrospective Analysis of Turkish Patients with Chronic Myeloproliferative Neoplasms.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2017, Mar-01, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Chronic Disease; Fe

2017
Multicenter Retrospective Analysis of Turkish Patients with Chronic Myeloproliferative Neoplasms.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2017, Mar-01, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Chronic Disease; Fe

2017
Incidence, Survival and Prevalence Statistics of Classical Myeloproliferative Neoplasm in Korea.
    Journal of Korean medical science, 2016, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Databases, Factual; Drug Prescr

2016
Incidence, Survival and Prevalence Statistics of Classical Myeloproliferative Neoplasm in Korea.
    Journal of Korean medical science, 2016, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Databases, Factual; Drug Prescr

2016
Clinical features and outcomes of patients with primary myelofibrosis in Japan: report of a 17-year nationwide survey by the Idiopathic Disorders of Hematopoietic Organs Research Committee of Japan.
    International journal of hematology, 2017, Volume: 105, Issue:1

    Topics: Adult; Androgens; Antineoplastic Agents; Cohort Studies; Erythrocyte Transfusion; Female; Hematopoie

2017
Clinical features and outcomes of patients with primary myelofibrosis in Japan: report of a 17-year nationwide survey by the Idiopathic Disorders of Hematopoietic Organs Research Committee of Japan.
    International journal of hematology, 2017, Volume: 105, Issue:1

    Topics: Adult; Androgens; Antineoplastic Agents; Cohort Studies; Erythrocyte Transfusion; Female; Hematopoie

2017
Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Erythropoietin; Humans; Hydroxyurea; Interferon-alph

2017
Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Erythropoietin; Humans; Hydroxyurea; Interferon-alph

2017
Ruxolitinib rechallenge in combination with hydroxyurea is effective in reverting cachexia and reducing blood transfusion demand and splenomegaly symptoms in a patient with primary myelofibrosis.
    Annals of hematology, 2017, Volume: 96, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cachexia; Drug Administration Sch

2017
Ruxolitinib rechallenge in combination with hydroxyurea is effective in reverting cachexia and reducing blood transfusion demand and splenomegaly symptoms in a patient with primary myelofibrosis.
    Annals of hematology, 2017, Volume: 96, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cachexia; Drug Administration Sch

2017
[Budd-Chiari syndrome--from diagnosis to treatment--case reports].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24, Issue:141

    Topics: Adult; Anticoagulants; Budd-Chiari Syndrome; Female; Humans; Hydroxyurea; Polycythemia; Primary Myel

2008
[Budd-Chiari syndrome--from diagnosis to treatment--case reports].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24, Issue:141

    Topics: Adult; Anticoagulants; Budd-Chiari Syndrome; Female; Humans; Hydroxyurea; Polycythemia; Primary Myel

2008
B-mode ultrasound and contrast-enhanced ultrasound pattern of focal extramedullary hematopoiesis of the spleen in a patient with myeloproliferative disease.
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2009, Volume: 30, Issue:3

    Topics: Aged; Biopsy, Needle; Bloodletting; Bone Marrow; Contrast Media; Diagnosis, Differential; Follow-Up

2009
B-mode ultrasound and contrast-enhanced ultrasound pattern of focal extramedullary hematopoiesis of the spleen in a patient with myeloproliferative disease.
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2009, Volume: 30, Issue:3

    Topics: Aged; Biopsy, Needle; Bloodletting; Bone Marrow; Contrast Media; Diagnosis, Differential; Follow-Up

2009
[Syndrome of extrahepatic portal hypertension and chronic abdominal ischemia in patient with subleukemic myelosis and congenital immunodeficiency].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:7

    Topics: Abdomen; Adult; Anticoagulants; Antineoplastic Agents; Chronic Disease; Female; Humans; Hydroxyurea;

2009
[Syndrome of extrahepatic portal hypertension and chronic abdominal ischemia in patient with subleukemic myelosis and congenital immunodeficiency].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:7

    Topics: Abdomen; Adult; Anticoagulants; Antineoplastic Agents; Chronic Disease; Female; Humans; Hydroxyurea;

2009
Bevacizumab may be active in myelofibrosis.
    Cancer investigation, 2010, Volume: 28, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizuma

2010
Bevacizumab may be active in myelofibrosis.
    Cancer investigation, 2010, Volume: 28, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizuma

2010
Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: results in 40 patients.
    Annals of hematology, 2010, Volume: 89, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antisickling Agents; Bone and Bones; Female; Humans; Hydroxy

2010
Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: results in 40 patients.
    Annals of hematology, 2010, Volume: 89, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antisickling Agents; Bone and Bones; Female; Humans; Hydroxy

2010
JAK inhibition in myelofibrosis.
    The New England journal of medicine, 2010, 12-16, Volume: 363, Issue:25

    Topics: Humans; Hydroxyurea; Janus Kinase 1; Janus Kinase 2; Mutation; Nitriles; Palliative Care; Primary My

2010
JAK inhibition in myelofibrosis.
    The New England journal of medicine, 2010, 12-16, Volume: 363, Issue:25

    Topics: Humans; Hydroxyurea; Janus Kinase 1; Janus Kinase 2; Mutation; Nitriles; Palliative Care; Primary My

2010
Increase in circulating CD4⁺CD25⁺Foxp3⁺ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α.
    Blood, 2011, Aug-25, Volume: 118, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Female; Forkhead Transcription Factors; Humans; Hydroxyurea; Int

2011
Increase in circulating CD4⁺CD25⁺Foxp3⁺ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α.
    Blood, 2011, Aug-25, Volume: 118, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Female; Forkhead Transcription Factors; Humans; Hydroxyurea; Int

2011
JAK2V617F allele burden is associated with transformation to myelofibrosis.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Cell Transformation, Neoplastic; Female; Humans; Hydroxyure

2012
JAK2V617F allele burden is associated with transformation to myelofibrosis.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Cell Transformation, Neoplastic; Female; Humans; Hydroxyure

2012
How I treat polycythemia vera.
    Blood, 2012, Jul-12, Volume: 120, Issue:2

    Topics: Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Janus Kinase 2; Janus Kinases; Ma

2012
How I treat polycythemia vera.
    Blood, 2012, Jul-12, Volume: 120, Issue:2

    Topics: Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Janus Kinase 2; Janus Kinases; Ma

2012
[Diagnostic image (117). A man with frequent blood transfusion and blister on his fingers. A form of porpheria cutanea tarda caused by excess iron].
    Nederlands tijdschrift voor geneeskunde, 2002, Dec-07, Volume: 146, Issue:49

    Topics: Aged; Blister; Diagnosis, Differential; Enzyme Inhibitors; Humans; Hydroxyurea; Iron Chelating Agent

2002
[Diagnostic image (117). A man with frequent blood transfusion and blister on his fingers. A form of porpheria cutanea tarda caused by excess iron].
    Nederlands tijdschrift voor geneeskunde, 2002, Dec-07, Volume: 146, Issue:49

    Topics: Aged; Blister; Diagnosis, Differential; Enzyme Inhibitors; Humans; Hydroxyurea; Iron Chelating Agent

2002
Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens.
    American journal of clinical pathology, 2003, Volume: 119, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Chroni

2003
Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens.
    American journal of clinical pathology, 2003, Volume: 119, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Chroni

2003
Paraneoplastic eosinophilic fasciitis: a case report.
    Rheumatology international, 2003, Volume: 23, Issue:5

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Eosinophilia; Fasciitis; Female; Humans; Hydroxyure

2003
Paraneoplastic eosinophilic fasciitis: a case report.
    Rheumatology international, 2003, Volume: 23, Issue:5

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Eosinophilia; Fasciitis; Female; Humans; Hydroxyure

2003
Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:6

    Topics: Biopsy; Bone Marrow; Busulfan; Disease Progression; Follow-Up Studies; Humans; Hydroxyurea; Interfer

2003
Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:6

    Topics: Biopsy; Bone Marrow; Busulfan; Disease Progression; Follow-Up Studies; Humans; Hydroxyurea; Interfer

2003
[Hydroxyurea-induced pneumonitis].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Jul-15, Volume: 98, Issue:7

    Topics: Antineoplastic Agents; Diagnosis, Differential; Humans; Hydroxyurea; Male; Middle Aged; Pneumonia; P

2003
[Hydroxyurea-induced pneumonitis].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Jul-15, Volume: 98, Issue:7

    Topics: Antineoplastic Agents; Diagnosis, Differential; Humans; Hydroxyurea; Male; Middle Aged; Pneumonia; P

2003
Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan.
    American journal of hematology, 2003, Volume: 74, Issue:1

    Topics: Acute Disease; Alkylating Agents; Busulfan; Chronic Disease; Drug Therapy, Combination; Female; Huma

2003
Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan.
    American journal of hematology, 2003, Volume: 74, Issue:1

    Topics: Acute Disease; Alkylating Agents; Busulfan; Chronic Disease; Drug Therapy, Combination; Female; Huma

2003
Bone marrow histopathology following cytoreductive therapy in chronic idiopathic myelofibrosis.
    Histopathology, 2003, Volume: 43, Issue:5

    Topics: Aged; Antineoplastic Agents; Bone Marrow; Busulfan; Female; Hematopoiesis; Humans; Hydroxyurea; Inte

2003
Bone marrow histopathology following cytoreductive therapy in chronic idiopathic myelofibrosis.
    Histopathology, 2003, Volume: 43, Issue:5

    Topics: Aged; Antineoplastic Agents; Bone Marrow; Busulfan; Female; Hematopoiesis; Humans; Hydroxyurea; Inte

2003
Hydroxyurea-induced pneumonitis in a patient with chronic idiopathic myelofibrosis after prolonged drug exposure.
    European journal of haematology, 2003, Volume: 71, Issue:5

    Topics: Diagnosis, Differential; Humans; Hydroxyurea; Male; Middle Aged; Pneumonia; Primary Myelofibrosis

2003
Hydroxyurea-induced pneumonitis in a patient with chronic idiopathic myelofibrosis after prolonged drug exposure.
    European journal of haematology, 2003, Volume: 71, Issue:5

    Topics: Diagnosis, Differential; Humans; Hydroxyurea; Male; Middle Aged; Pneumonia; Primary Myelofibrosis

2003
Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene.
    Haematologica, 2004, Volume: 89, Issue:10

    Topics: Benzamides; Biomarkers; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 5; Disease Progression

2004
Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene.
    Haematologica, 2004, Volume: 89, Issue:10

    Topics: Benzamides; Biomarkers; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 5; Disease Progression

2004
[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases].
    Voprosy onkologii, 2004, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan;

2004
[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases].
    Voprosy onkologii, 2004, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan;

2004
When and how to treat essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxyurea; Leukemia

2005
When and how to treat essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxyurea; Leukemia

2005
Agnogenic myeloid metaplasia with pulmonary hematopoiesis.
    Hematology (Amsterdam, Netherlands), 2005, Volume: 10, Issue:6

    Topics: Aged; Fatal Outcome; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Primary Myelofibrosis

2005
Agnogenic myeloid metaplasia with pulmonary hematopoiesis.
    Hematology (Amsterdam, Netherlands), 2005, Volume: 10, Issue:6

    Topics: Aged; Fatal Outcome; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Primary Myelofibrosis

2005
Effects of anagrelide on megakaryopoiesis and platelet production.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Marrow; Cell Differentiation; Drug Evaluation; Human

2006
Effects of anagrelide on megakaryopoiesis and platelet production.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Marrow; Cell Differentiation; Drug Evaluation; Human

2006
[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:6

    Topics: Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Lung; Male; Middle Aged; Pleural Effusion; Prima

2006
[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:6

    Topics: Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Lung; Male; Middle Aged; Pleural Effusion; Prima

2006
Multiple granulocytic sarcomas in essential thrombocythemia.
    International journal of hematology, 2006, Volume: 84, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Chromosome Deletion; Chromosomes,

2006
Multiple granulocytic sarcomas in essential thrombocythemia.
    International journal of hematology, 2006, Volume: 84, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Chromosome Deletion; Chromosomes,

2006
Application of PRV-1 mRNA expression level and JAK2V617F mutation for the differentiating between polycytemia vera and secondary erythrocytosis and assessment of treatment by interferon or hydroxyurea.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:6

    Topics: Diagnosis, Differential; GPI-Linked Proteins; Humans; Hydroxyurea; Interferon-alpha; Isoantigens; Ja

2007
Application of PRV-1 mRNA expression level and JAK2V617F mutation for the differentiating between polycytemia vera and secondary erythrocytosis and assessment of treatment by interferon or hydroxyurea.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:6

    Topics: Diagnosis, Differential; GPI-Linked Proteins; Humans; Hydroxyurea; Interferon-alpha; Isoantigens; Ja

2007
Improvement of fibrosis in a patient with chronic myeloproliferative disease.
    British journal of haematology, 2007, Volume: 139, Issue:3

    Topics: Adult; Biopsy; Follow-Up Studies; Humans; Hydroxyurea; Interferon-alpha; Male; Nucleic Acid Synthesi

2007
Improvement of fibrosis in a patient with chronic myeloproliferative disease.
    British journal of haematology, 2007, Volume: 139, Issue:3

    Topics: Adult; Biopsy; Follow-Up Studies; Humans; Hydroxyurea; Interferon-alpha; Male; Nucleic Acid Synthesi

2007
[Coexistence of scleroderma-like syndrome and idiopathic myelofibrosis in a 54-year-old female patient: case report].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8

    Topics: Antineoplastic Agents; Azathioprine; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive

2007
[Coexistence of scleroderma-like syndrome and idiopathic myelofibrosis in a 54-year-old female patient: case report].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8

    Topics: Antineoplastic Agents; Azathioprine; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive

2007
The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Adult; Age Factors; Aged; Alleles; Cohort Studies; DNA Mutational Analysis; Drug Resistance; Female;

2008
The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Adult; Age Factors; Aged; Alleles; Cohort Studies; DNA Mutational Analysis; Drug Resistance; Female;

2008
[Therapy of chronic myeloid leukemia].
    Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:2

    Topics: Busulfan; Chromosomes, Human, 21-22 and Y; Drug Administration Schedule; Humans; Hydroxyurea; Leukem

1981
[Therapy of chronic myeloid leukemia].
    Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:2

    Topics: Busulfan; Chromosomes, Human, 21-22 and Y; Drug Administration Schedule; Humans; Hydroxyurea; Leukem

1981
Characterization of hypocholesterolemia in myeloproliferative disease. Relation to disease manifestations and activity.
    The American journal of medicine, 1981, Volume: 71, Issue:4

    Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hydroxyurea; Lipoproteins, HD

1981
Characterization of hypocholesterolemia in myeloproliferative disease. Relation to disease manifestations and activity.
    The American journal of medicine, 1981, Volume: 71, Issue:4

    Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hydroxyurea; Lipoproteins, HD

1981
Paroxysmal nocturnal hemoglobinuria with myelofibrosis: progression to acute myeloblastic leukemia.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Antigens, CD; Blood Proteins; CD55 Antigens; CD59 Antigens; Erythrocytes; Flow Cytometry; Granulocyt

1993
Paroxysmal nocturnal hemoglobinuria with myelofibrosis: progression to acute myeloblastic leukemia.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Antigens, CD; Blood Proteins; CD55 Antigens; CD59 Antigens; Erythrocytes; Flow Cytometry; Granulocyt

1993
An unwanted side effect of hydroxyurea in a patient with idiopathic myelofibrosis.
    Annals of hematology, 1995, Volume: 70, Issue:5

    Topics: Aged; Fever; Humans; Hydroxyurea; Male; Primary Myelofibrosis

1995
An unwanted side effect of hydroxyurea in a patient with idiopathic myelofibrosis.
    Annals of hematology, 1995, Volume: 70, Issue:5

    Topics: Aged; Fever; Humans; Hydroxyurea; Male; Primary Myelofibrosis

1995
[A case of chronic neutrophilic leukemia accompanied with severe bone marrow fibrosis which was effectively treated by hydroxyurea].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:11

    Topics: Humans; Hydroxyurea; Leukemia, Neutrophilic, Chronic; Male; Middle Aged; Primary Myelofibrosis

1994
[A case of chronic neutrophilic leukemia accompanied with severe bone marrow fibrosis which was effectively treated by hydroxyurea].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:11

    Topics: Humans; Hydroxyurea; Leukemia, Neutrophilic, Chronic; Male; Middle Aged; Primary Myelofibrosis

1994
Hydroxyurea and lower leg ulcers.
    Cutis, 1993, Volume: 52, Issue:4

    Topics: Aged; Female; Humans; Hydroxyurea; Leg Ulcer; Male; Middle Aged; Polycythemia Vera; Primary Myelofib

1993
Hydroxyurea and lower leg ulcers.
    Cutis, 1993, Volume: 52, Issue:4

    Topics: Aged; Female; Humans; Hydroxyurea; Leg Ulcer; Male; Middle Aged; Polycythemia Vera; Primary Myelofib

1993
Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Busulfan; Cell Transformation, Neoplastic;

1996
Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Busulfan; Cell Transformation, Neoplastic;

1996
Pleural effusion secondary to extramedullary haemopoiesis in a patient with idiopathic myelofibrosis responding to pleurodesis and hydroxyurea.
    Clinical and laboratory haematology, 1997, Volume: 19, Issue:4

    Topics: Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Middle Aged; Pleural Effusion; Pleurodesis

1997
Pleural effusion secondary to extramedullary haemopoiesis in a patient with idiopathic myelofibrosis responding to pleurodesis and hydroxyurea.
    Clinical and laboratory haematology, 1997, Volume: 19, Issue:4

    Topics: Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Middle Aged; Pleural Effusion; Pleurodesis

1997
Treatment of myeloproliferative disorders with hydroxyurea: effects on red blood cell geometry and deformability.
    Blood, 1998, May-15, Volume: 91, Issue:10

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Cats; Cell Size; Erythrocyte Deformability; Erythr

1998
Treatment of myeloproliferative disorders with hydroxyurea: effects on red blood cell geometry and deformability.
    Blood, 1998, May-15, Volume: 91, Issue:10

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Cats; Cell Size; Erythrocyte Deformability; Erythr

1998
Acute promyelocytic leukemia in a patient with idiopathic myelofibrosis.
    Leukemia, 1999, Volume: 13, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Idarubicin; Leuke

1999
Acute promyelocytic leukemia in a patient with idiopathic myelofibrosis.
    Leukemia, 1999, Volume: 13, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Idarubicin; Leuke

1999
Effects of interferon and hydroxyurea on bone marrow fibrosis in chronic myelogenous leukaemia: a comparative retrospective multicentre histological and clinical study.
    British journal of haematology, 2000, Volume: 108, Issue:1

    Topics: Adult; Antineoplastic Agents; Biopsy; Cell Division; Cohort Studies; Female; Humans; Hydroxyurea; In

2000
Effects of interferon and hydroxyurea on bone marrow fibrosis in chronic myelogenous leukaemia: a comparative retrospective multicentre histological and clinical study.
    British journal of haematology, 2000, Volume: 108, Issue:1

    Topics: Adult; Antineoplastic Agents; Biopsy; Cell Division; Cohort Studies; Female; Humans; Hydroxyurea; In

2000
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free

2000
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free

2000
Effects of chemotherapy (busulfan-hydroxyurea) and interferon-alfa on bone marrow morphologic features in chronic myelogenous leukemia. Histochemical and morphometric study on sequential trephine biopsy specimens with special emphasis on dynamic features.
    American journal of clinical pathology, 2000, Volume: 114, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Bone Marrow; Busulfan; Disease Pro

2000
Effects of chemotherapy (busulfan-hydroxyurea) and interferon-alfa on bone marrow morphologic features in chronic myelogenous leukemia. Histochemical and morphometric study on sequential trephine biopsy specimens with special emphasis on dynamic features.
    American journal of clinical pathology, 2000, Volume: 114, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Bone Marrow; Busulfan; Disease Pro

2000
Changing patterns of histological subgroups during therapy of Ph1+ chronic myelogenous leukaemia.
    Histopathology, 2000, Volume: 37, Issue:4

    Topics: Adult; Antineoplastic Agents; Bone Marrow; Busulfan; Granulocytes; Humans; Hydroxyurea; Interferon a

2000
Changing patterns of histological subgroups during therapy of Ph1+ chronic myelogenous leukaemia.
    Histopathology, 2000, Volume: 37, Issue:4

    Topics: Adult; Antineoplastic Agents; Bone Marrow; Busulfan; Granulocytes; Humans; Hydroxyurea; Interferon a

2000
Prognostic impact of bone marrow erythropoietic precursor cells and myelofibrosis at diagnosis of Ph1+ chronic myelogenous leukaemia--a multicentre study on 495 patients.
    British journal of haematology, 2001, Volume: 112, Issue:3

    Topics: Adult; Bone Marrow; Busulfan; Erythroid Precursor Cells; Female; Humans; Hydroxyurea; Immunohistoche

2001
Prognostic impact of bone marrow erythropoietic precursor cells and myelofibrosis at diagnosis of Ph1+ chronic myelogenous leukaemia--a multicentre study on 495 patients.
    British journal of haematology, 2001, Volume: 112, Issue:3

    Topics: Adult; Bone Marrow; Busulfan; Erythroid Precursor Cells; Female; Humans; Hydroxyurea; Immunohistoche

2001
Subcutaneous extramedullary hematopoiesis in a patient with secondary myelofibrosis following polycythemia vera.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Aged; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Megakaryocytes; Myeloid Cells; Pol

2001
Subcutaneous extramedullary hematopoiesis in a patient with secondary myelofibrosis following polycythemia vera.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Aged; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Megakaryocytes; Myeloid Cells; Pol

2001
Diagnostic and clinical relevance of the number of circulating CD34(+) cells in myelofibrosis with myeloid metaplasia.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Cell Count; Female; Humans; Hydroxyurea; Male; Middl

2001
Diagnostic and clinical relevance of the number of circulating CD34(+) cells in myelofibrosis with myeloid metaplasia.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Cell Count; Female; Humans; Hydroxyurea; Male; Middl

2001
Therapy-related changes of CD34+ progenitor cells in chronic myeloid leukemia: a morphometric study on sequential trephine biopsies.
    Journal of hematotherapy & stem cell research, 2001, Volume: 10, Issue:6

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Case-Cont

2001
Therapy-related changes of CD34+ progenitor cells in chronic myeloid leukemia: a morphometric study on sequential trephine biopsies.
    Journal of hematotherapy & stem cell research, 2001, Volume: 10, Issue:6

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Case-Cont

2001
Unusually prolonged survival of a case of acute megakaryoblastic leukemia secondary to long-standing polycythemia vera.
    Leukemia research, 2002, Volume: 26, Issue:7

    Topics: Bone Marrow; Combined Modality Therapy; Disease Progression; Erythrocyte Transfusion; Female; Humans

2002
Unusually prolonged survival of a case of acute megakaryoblastic leukemia secondary to long-standing polycythemia vera.
    Leukemia research, 2002, Volume: 26, Issue:7

    Topics: Bone Marrow; Combined Modality Therapy; Disease Progression; Erythrocyte Transfusion; Female; Humans

2002
Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case.
    Chemotherapy, 1978, Volume: 24, Issue:5

    Topics: Female; Humans; Hydroxyurea; Leukemia, Myeloid; Middle Aged; Primary Myelofibrosis; Punctures; Skin

1978
Chronic granulocytic leukemia cutis treated with hydroxyurea. Report of a case.
    Chemotherapy, 1978, Volume: 24, Issue:5

    Topics: Female; Humans; Hydroxyurea; Leukemia, Myeloid; Middle Aged; Primary Myelofibrosis; Punctures; Skin

1978
Skin changes secondary to hydroxyurea therapy.
    Archives of dermatology, 1975, Volume: 111, Issue:2

    Topics: Administration, Oral; Adult; Biopsy; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count

1975
Skin changes secondary to hydroxyurea therapy.
    Archives of dermatology, 1975, Volume: 111, Issue:2

    Topics: Administration, Oral; Adult; Biopsy; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count

1975
Hypercalcemia in idiopathic myelofibrosis: modulation of calcium and collagen homeostasis by 1,25-dihydroxyvitamin D3.
    American journal of hematology, 1992, Volume: 39, Issue:3

    Topics: Adult; Biopsy; Bone Marrow; Calcitriol; Calcium; Collagen; Homeostasis; Humans; Hydroxyurea; Hyperca

1992
Hypercalcemia in idiopathic myelofibrosis: modulation of calcium and collagen homeostasis by 1,25-dihydroxyvitamin D3.
    American journal of hematology, 1992, Volume: 39, Issue:3

    Topics: Adult; Biopsy; Bone Marrow; Calcitriol; Calcium; Collagen; Homeostasis; Humans; Hydroxyurea; Hyperca

1992
Management of myelofibrosis with intermittent hydroxyurea.
    British journal of haematology, 1991, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Drug Administration Schedule; Female; Humans; Hydroxyurea; Male; Middle Age

1991
Management of myelofibrosis with intermittent hydroxyurea.
    British journal of haematology, 1991, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Drug Administration Schedule; Female; Humans; Hydroxyurea; Male; Middle Age

1991
Clinical significance of serum pro-collagen III in chronic myeloproliferative disorders.
    European journal of haematology, 1990, Volume: 45, Issue:5

    Topics: Aged; Bloodletting; Humans; Hydroxyurea; Myeloproliferative Disorders; Polycythemia; Polycythemia Ve

1990
Clinical significance of serum pro-collagen III in chronic myeloproliferative disorders.
    European journal of haematology, 1990, Volume: 45, Issue:5

    Topics: Aged; Bloodletting; Humans; Hydroxyurea; Myeloproliferative Disorders; Polycythemia; Polycythemia Ve

1990
Cutaneous extramedullary hematopoiesis with a preponderance of atypical megakaryocytes in myelofibrosis.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:2 Pt 2

    Topics: Aged; Biopsy; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Megakaryocytes; Primary Myel

1990
Cutaneous extramedullary hematopoiesis with a preponderance of atypical megakaryocytes in myelofibrosis.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:2 Pt 2

    Topics: Aged; Biopsy; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Megakaryocytes; Primary Myel

1990
Reversal of myelofibrosis by hydroxyurea.
    European journal of haematology, 1990, Volume: 44, Issue:1

    Topics: Bone Marrow; Follow-Up Studies; Hemoglobins; Humans; Hydroxyurea; Leukocyte Count; Middle Aged; Plat

1990
Reversal of myelofibrosis by hydroxyurea.
    European journal of haematology, 1990, Volume: 44, Issue:1

    Topics: Bone Marrow; Follow-Up Studies; Hemoglobins; Humans; Hydroxyurea; Leukocyte Count; Middle Aged; Plat

1990
The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes.
    Blood, 1985, Volume: 66, Issue:2

    Topics: Adult; Aged; Erythrocyte Indices; Female; Fetal Hemoglobin; Humans; Hydroxyurea; Male; Middle Aged;

1985
The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes.
    Blood, 1985, Volume: 66, Issue:2

    Topics: Adult; Aged; Erythrocyte Indices; Female; Fetal Hemoglobin; Humans; Hydroxyurea; Male; Middle Aged;

1985
Splenic irradiation in the treatment of patients with chronic myelogenous leukemia or myelofibrosis with myeloid metaplasia. Results of daily and intermittent fractionation with and without concomitant hydroxyurea.
    Cancer, 1986, Sep-15, Volume: 58, Issue:6

    Topics: Adult; Aged; Child; Evaluation Studies as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Mal

1986
Splenic irradiation in the treatment of patients with chronic myelogenous leukemia or myelofibrosis with myeloid metaplasia. Results of daily and intermittent fractionation with and without concomitant hydroxyurea.
    Cancer, 1986, Sep-15, Volume: 58, Issue:6

    Topics: Adult; Aged; Child; Evaluation Studies as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Mal

1986
Decreased natural killer (NK) activity in patients with myeloproliferative disorders.
    Cancer, 1989, Sep-01, Volume: 64, Issue:5

    Topics: Bloodletting; Humans; Hydroxyurea; Interferon Type I; Interleukin-2; Killer Cells, Natural; Myelopro

1989
Decreased natural killer (NK) activity in patients with myeloproliferative disorders.
    Cancer, 1989, Sep-01, Volume: 64, Issue:5

    Topics: Bloodletting; Humans; Hydroxyurea; Interferon Type I; Interleukin-2; Killer Cells, Natural; Myelopro

1989
Management of polycythaemia vera, essential thrombocythaemia and myelofibrosis with hydroxyurea.
    European journal of haematology, 1988, Volume: 41, Issue:4

    Topics: Drug Evaluation; Humans; Hydroxyurea; Platelet Count; Polycythemia Vera; Primary Myelofibrosis; Thro

1988
Management of polycythaemia vera, essential thrombocythaemia and myelofibrosis with hydroxyurea.
    European journal of haematology, 1988, Volume: 41, Issue:4

    Topics: Drug Evaluation; Humans; Hydroxyurea; Platelet Count; Polycythemia Vera; Primary Myelofibrosis; Thro

1988
Small intestinal myeloid metaplasia.
    JAMA, 1988, May-06, Volume: 259, Issue:17

    Topics: Aged; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Intestinal Diseases; Intestine, Sm

1988
Small intestinal myeloid metaplasia.
    JAMA, 1988, May-06, Volume: 259, Issue:17

    Topics: Aged; Female; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Intestinal Diseases; Intestine, Sm

1988
Acute leukemia in polycythemia vera.
    Seminars in hematology, 1986, Volume: 23, Issue:2

    Topics: Acute Disease; Antigens, Neoplasm; Bloodletting; Chlorambucil; Chromosome Aberrations; Chromosome Di

1986
Acute leukemia in polycythemia vera.
    Seminars in hematology, 1986, Volume: 23, Issue:2

    Topics: Acute Disease; Antigens, Neoplasm; Bloodletting; Chlorambucil; Chromosome Aberrations; Chromosome Di

1986
Hypereosinophilic syndrome associated with polycythemia vera.
    Archives of internal medicine, 1986, Volume: 146, Issue:7

    Topics: Eosinophilia; Female; Humans; Hydroxyurea; Middle Aged; Polycythemia Vera; Primary Myelofibrosis; Re

1986
Hypereosinophilic syndrome associated with polycythemia vera.
    Archives of internal medicine, 1986, Volume: 146, Issue:7

    Topics: Eosinophilia; Female; Humans; Hydroxyurea; Middle Aged; Polycythemia Vera; Primary Myelofibrosis; Re

1986
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
    Scandinavian journal of haematology, 1985, Volume: 35, Issue:3

    Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyu

1985
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
    Scandinavian journal of haematology, 1985, Volume: 35, Issue:3

    Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyu

1985
Thrombocytosis in chronic granulocytic leukemia: incidence and clinical significance.
    Blood, 1974, Volume: 44, Issue:4

    Topics: Anemia; Azauridine; Blood Cell Count; Blood Platelets; Bone Marrow Examination; Busulfan; Cell Trans

1974
Thrombocytosis in chronic granulocytic leukemia: incidence and clinical significance.
    Blood, 1974, Volume: 44, Issue:4

    Topics: Anemia; Azauridine; Blood Cell Count; Blood Platelets; Bone Marrow Examination; Busulfan; Cell Trans

1974