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hydroxyurea and Precancerous Conditions

hydroxyurea has been researched along with Precancerous Conditions in 8 studies

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"An elderly woman receiving chronic hydroxyurea therapy for myelodysplasia developed a dermatomyositis-like eruption that was misdiagnosed as true dermatomyositis, leading to continuation of hydroxyurea."7.76Hydroxyurea-associated dermatomyositis-like eruption demonstrating abnormal epidermal p53 expression: a potential premalignant manifestation of chronic hydroxyurea and UV radiation exposure. ( Burruss, JB; Callen, JP; Cely, SJ; Kalajian, AH; Malone, JC, 2010)
"An elderly woman receiving chronic hydroxyurea therapy for myelodysplasia developed a dermatomyositis-like eruption that was misdiagnosed as true dermatomyositis, leading to continuation of hydroxyurea."3.76Hydroxyurea-associated dermatomyositis-like eruption demonstrating abnormal epidermal p53 expression: a potential premalignant manifestation of chronic hydroxyurea and UV radiation exposure. ( Burruss, JB; Callen, JP; Cely, SJ; Kalajian, AH; Malone, JC, 2010)
" A dose-response relationship for the UV-induced DNA repair synthesis was established for each individual."2.64Ultraviolet-induced dna repair synthesis in lymphocytes from patients with actinic keratosis. ( Lambert, B; Ringborg, U; Swanbeck, G, 1976)
"Hydroxyurea is an antimetabolite primarily used to treat myeloproliferative disorders, and chronic treatment is associated with many cutaneous adverse effects ranging in severity from ichthyosis to aggressive nonmelanoma skin cancer."1.46A patient case highlighting the myriad of cutaneous adverse effects of prolonged use of hydroxyurea. ( Aires, D; Neill, B; Neill, J; Rajpara, A; Ryser, T, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Neill, B1
Ryser, T1
Neill, J1
Aires, D1
Rajpara, A1
de Unamuno-Bustos, B1
Ballester-Sánchez, R1
Sabater Marco, V1
Vilata-Corell, JJ1
Kalajian, AH1
Cely, SJ1
Malone, JC1
Burruss, JB1
Callen, JP1
Sanchez-Palacios, C1
Guitart, J1
Bodell, WJ1
Banerjee, MR1
Lambert, B1
Ringborg, U1
Swanbeck, G1
Delacrétaz, J1
Zeindl-Eberhart, E1
Rabes, HM1

Reviews

1 review available for hydroxyurea and Precancerous Conditions

ArticleYear
Hydroxyurea-associated squamous dysplasia.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Humans; Hydroxyurea; Keratosis; Male; Precancerous Conditions; Skin

2004

Trials

1 trial available for hydroxyurea and Precancerous Conditions

ArticleYear
Ultraviolet-induced dna repair synthesis in lymphocytes from patients with actinic keratosis.
    The Journal of investigative dermatology, 1976, Volume: 67, Issue:5

    Topics: Aged; Clinical Trials as Topic; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation;

1976

Other Studies

6 other studies available for hydroxyurea and Precancerous Conditions

ArticleYear
A patient case highlighting the myriad of cutaneous adverse effects of prolonged use of hydroxyurea.
    Dermatology online journal, 2017, Nov-15, Volume: 23, Issue:11

    Topics: Aged; Biopsy; Carcinoma, Squamous Cell; Dermatomyositis; Humans; Hydroxyurea; Keratosis; Male; Polyc

2017
Dermatomyositis-like eruption associated with hydroxyurea therapy: a premalignant condition?
    Actas dermo-sifiliograficas, 2014, Volume: 105, Issue:9

    Topics: Aged; Dermatomyositis; Diagnosis, Differential; Drug Eruptions; Drug Substitution; Erythema; Female;

2014
Hydroxyurea-associated dermatomyositis-like eruption demonstrating abnormal epidermal p53 expression: a potential premalignant manifestation of chronic hydroxyurea and UV radiation exposure.
    Archives of dermatology, 2010, Volume: 146, Issue:3

    Topics: Aged, 80 and over; Dermatomyositis; Diagnosis, Differential; DNA, Neoplasm; Drug Eruptions; Epidermi

2010
DNA repair in normal and preneoplastic mammary tissues.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Bromodeoxyuridine; DNA Repair; DNA Replication; DNA, Neoplasm; Female; Hydroxyurea; In Vitr

1978
[Current aspects of melanoma].
    Therapeutische Umschau. Revue therapeutique, 1976, Volume: 33, Issue:8

    Topics: Antigens, Neoplasm; B-Lymphocytes; Drug Therapy, Combination; Humans; Hydroxyurea; Imidazoles; Melan

1976
Variant protein patterns in hepatomas and transformed liver cell lines as determined by high resolution two-dimensional gel electrophoresis (2DE).
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Electropho

1992