hydroxyurea has been researched along with Peritonitis in 3 studies
Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a murine model of arachidonic acid-induced ear inflammation, the LTA(4)H inhibitor, JNJ-26993135 (1-[4-(benzothiazol-2-yloxy)-benzyl]-piperidine-4-carboxylic acid), dose-dependently inhibited ex vivo LTB(4) production in blood, in parallel with dose-dependent inhibition of neutrophil influx (ED(50), 1-3 mg/kg) and ear edema." | 3.74 | Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton. ( Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Jiang, X; Karlsson, L; Lundeen, KA; Rao, NL; Riley, JP; Williams, KN; Xue, X, 2007) |
| "A novel series of N-[(2-benzothiazolylthio)alkyl]-N'-hydroxyurea derivatives (9-25) was synthesized and evaluated for biological activity as inhibitors of 5-lipoxygenase both in vivo (mouse zymosan peritonitis assay) and in vitro (Ca2+ ionophore-stimulated human peripheral blood leukocyte model)." | 3.68 | Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid. ( Greco, MN; Hageman, WE; Persico, FJ; Powell, ET; Tighe, JJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| dos Santos, JL | 1 |
| Lanaro, C | 1 |
| Lima, LM | 1 |
| Gambero, S | 1 |
| Franco-Penteado, CF | 1 |
| Alexandre-Moreira, MS | 1 |
| Wade, M | 1 |
| Yerigenahally, S | 1 |
| Kutlar, A | 1 |
| Meiler, SE | 1 |
| Costa, FF | 1 |
| Chung, M | 1 |
| Rao, NL | 1 |
| Dunford, PJ | 1 |
| Xue, X | 1 |
| Jiang, X | 1 |
| Lundeen, KA | 1 |
| Coles, F | 1 |
| Riley, JP | 1 |
| Williams, KN | 1 |
| Grice, CA | 1 |
| Edwards, JP | 1 |
| Karlsson, L | 1 |
| Fourie, AM | 1 |
| Greco, MN | 1 |
| Hageman, WE | 1 |
| Powell, ET | 1 |
| Tighe, JJ | 1 |
| Persico, FJ | 1 |
3 other studies available for hydroxyurea and Peritonitis
| Article | Year |
|---|---|
Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.
Topics: Acetic Acid; Analgesics; Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Antisickling Agents | 2011 |
Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Ascitic Fluid; Benzothiazoles; D | 2007 |
Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid.
Topics: Animals; Benzothiazoles; Calcimycin; Dogs; Humans; Hydroxamic Acids; Hydroxyurea; Leukocytes; Leukot | 1992 |