Page last updated: 2024-10-28

hydroxyurea and Ovarian Neoplasms

hydroxyurea has been researched along with Ovarian Neoplasms in 12 studies

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"The overall response rate in the 18 cervical cancer patients was 89% (78% complete, 11% partial)."2.69Phase I trial of concomitant chemoradiotherapy for cervical cancer and other advanced pelvic malignancies. ( Fleming, G; Mundt, AJ; Quiet, C; Rotmensch, J; Waggoner, S, 1999)
"In cultured ovarian cancer cells, 5-LOX metabolites were increased under hypoxic conditons."1.42Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration. ( Fan, B; Gao, W; Li, B; Li, M; Liu, H; Qu, X; Shao, Q; Wang, Q; Wen, Z; Xie, Q; Yang, Y; Yu, J; Zhao, F, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, L1
Zhao, Y1
Quan, C1
Ji, W1
Zhu, J1
Huang, Y1
Guan, R1
Sun, D1
Jin, Y1
Meng, X1
Zhang, C1
Yu, Y1
Bai, J1
Sun, W1
Fu, S1
Wen, Z1
Liu, H1
Li, M1
Li, B1
Gao, W1
Shao, Q1
Fan, B1
Zhao, F1
Wang, Q1
Xie, Q1
Yang, Y1
Yu, J1
Qu, X1
Yilmaz, B1
Teksoz, S1
Kilcar, AY1
Ucar, E1
Ichedef, C1
Medine, EI1
Ari, K1
Rupniak, HT1
Whelan, RD1
Hill, BT1
Strobel, T1
Swanson, L1
Korsmeyer, S1
Cannistra, SA1
Mundt, AJ1
Rotmensch, J1
Waggoner, S1
Quiet, C1
Fleming, G1
Raymond, E1
Faivre, S1
Weiss, G1
McGill, J1
Davidson, K1
Izbicka, E1
Kuhn, JG1
Allred, C1
Clark, GM1
Von Hoff, DD1
Mathews, CK1
Wollner, N1
Lieberman, P1
Exelby, P1
D'angio, G1
Burchenal, J1
Fang, S1
Murphy, ML1
Brady, LW1
Chiu, CS1
Chan, AK1
Wright, JA1
Ariel, IM1

Reviews

1 review available for hydroxyurea and Ovarian Neoplasms

ArticleYear
Combined modality therapy of gynecologic cancer.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Evaluation Studies as Topic; Female; Genit

1975

Trials

2 trials available for hydroxyurea and Ovarian Neoplasms

ArticleYear
Phase I trial of concomitant chemoradiotherapy for cervical cancer and other advanced pelvic malignancies.
    Gynecologic oncology, 1999, Volume: 72, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth

1999
Effects of hydroxyurea on extrachromosomal DNA in patients with advanced ovarian carcinomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chromosomes, Human, Pai

2001

Other Studies

9 other studies available for hydroxyurea and Ovarian Neoplasms

ArticleYear
Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; DNA Damage; DNA, Neoplas

2013
Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration.
    Oncogene, 2015, Mar-05, Volume: 34, Issue:10

    Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Line; Cell Line, Tumor; Chemotaxis, Leukocyte; Disease Mo

2015
In Vitro/In Vivo Evaluation of Radiolabeled [(99m)Tc(CO)3](+)-Hydroxyurea and Fluorescein Isothiocyanate-Hydroxyurea.
    Cancer biotherapy & radiopharmaceuticals, 2016, Volume: 31, Issue:1

    Topics: Animals; Breast Neoplasms; Dextrans; Enzyme Inhibitors; Female; Fluorescein-5-isothiocyanate; Hydrox

2016
Concentration and time-dependent inter-relationships for antitumour drug cytotoxicities against tumour cells in vitro.
    International journal of cancer, 1983, Jul-15, Volume: 32, Issue:1

    Topics: Antineoplastic Agents; Cell Survival; Cisplatin; Clone Cells; Dose-Response Relationship, Drug; Doxo

1983
BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Nov-26, Volume: 93, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carboplatin; C

1996
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
    Experimental cell research, 1975, Volume: 92, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture M

1975
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
    The British journal of cancer. Supplement, 1975, Volume: 2

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosp

1975
Inhibition of mammalian ribonucleotide reductase by cis-diamminedichloroplatinum(II).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1992, Volume: 70, Issue:12

    Topics: Animals; Cell Division; Cisplatin; Colonic Neoplasms; Drug Resistance; Escherichia coli; Female; Hum

1992
Anticancer therapy with hydrea: comparative study of daily vs. intermittent oral dosage.
    Journal of surgical oncology, 1974, Volume: 6, Issue:1

    Topics: Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Dr

1974