hydroxyurea has been researched along with Myelomonocytic Leukemia, Chronic in 33 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " After two patients had a rapid increase in WBC counts and clinical signs reminiscent of the 'ATRA syndrome' seen in acute promyelocytic leukemia, with fatal outcome in one of them, it was decided to add hydroxyurea (HY) to ATRA to patients with high WBC at inclusion or during ATRA treatment, and no more cases of ATRA syndrome were seen." | 5.08 | All-trans retinoic acid in adult chronic myelomonocytic leukemia: results of a pilot study. ( Cambier, N; Chomienne, C; Fenaux, P; Guerci, A; Menot, ML; Wattel, E, 1996) |
| " Before the appearance of CMML, he received a total dose of 2,894 mg of nimustine for the treatment of a pontine glioma over 12 years." | 3.69 | Therapy-related chronic myelomonocytic leukaemia with bone marrow eosinophilia associated with der(11)t(1;11)(q21;q14). ( Amemiya, Y; Hatake, K; Miura, Y; Miyata, T; Muroi, K; Saito, M, 1996) |
| "Except for chronic myeloid leukemia, which is defined by the presence of the Philadelphia (Ph) chromosome, and the classic Ph chromosome-negative MPNs (polycythemia vera, essential thrombocythemia, and primary myelofibrosis), clonal neutrophilic neoplasms historically have been challenging to diagnose and classify." | 2.72 | Diagnosis and management of neutrophilic myeloid neoplasms. ( Gotlib, J; Schwede, M; Shomali, W, 2021) |
| " Initial dosage was 1 g/d for HY and 150 mg/week for VP16, orally (doubled in case of visceral involvement)." | 2.68 | A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Français des Myélodysplasies and European CMML Group. ( Copplestone, A; Couteaux, ME; Deconinck, E; Economopoulos, T; Fenaux, P; Foussard, C; Guerci, A; Hecquet, B; Mahé, B; Michaux, JL; Mufti, G; Oscier, D; Pegourié, B; Resegotti, L; Stoppa, AM; Voglova, V; Wattel, E, 1996) |
| "The presence of pleural effusion is usually associated with uncontrolled leukocytosis and increased monocytes." | 2.66 | Chronic myelomonocytic leukemia (CMML)-0 with pleural effusion as first manifestation: A case report. ( Fu, L; Hu, L; Hu, M; Zheng, B, 2020) |
| "Despite treatment for pulmonary hypertension and provision of respiratory support, the patient died." | 1.33 | Pulmonary hypertension in a child with juvenile myelomonocytic leukemia secondary to pulmonary leukemic cell infiltration. ( Alioglu, B; Demirhan, B; Erbay, A; Ozbek, N; Ozyurek, E; Varan, B, 2006) |
| "It has been reported that trisomy 14 is associated with myeloid malignancies, but a case with increased platelet count has also been reported." | 1.31 | Trisomy 14 with thrombocytosis and monocytosis. ( Kaya, H; Maeno, K; Matsuda, T; Nakamura, S; Ohtake, S; Okafuji, K; Tanaka, N; Terasaki, Y, 2000) |
| "Treatment with prednisolone and azathioprine was initiated." | 1.30 | [Pyoderma gangrenosum and portal vein thrombosis in a 33-year-old female patient]. ( Berr, F; Halm, U; Mössner, J; Paasch, U; Pönisch, W; Schiefke, I, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 8 (24.24) | 2.80 |
| Authors | Studies |
|---|---|
| Reiser, J | 1 |
| Geissler, K | 3 |
| Rezazadeh, A | 1 |
| Deininger, M | 1 |
| Atallah, E | 1 |
| Zhao, Y | 1 |
| Maule, J | 1 |
| Li, Y | 1 |
| Neff, J | 1 |
| McCall, CM | 1 |
| Hao, T | 1 |
| Yang, W | 1 |
| Rehder, C | 1 |
| Yang, LH | 1 |
| Wang, E | 1 |
| Chopra, J | 1 |
| Hiew, HJ | 1 |
| Cumpstey, A | 1 |
| Cagampang, F | 1 |
| Jenner, MW | 1 |
| Dushianthan, A | 1 |
| Hu, L | 1 |
| Zheng, B | 1 |
| Fu, L | 1 |
| Hu, M | 1 |
| Pleyer, L | 2 |
| Leisch, M | 1 |
| Kourakli, A | 1 |
| Padron, E | 2 |
| Maciejewski, JP | 1 |
| Xicoy Cirici, B | 1 |
| Kaivers, J | 1 |
| Ungerstedt, J | 1 |
| Heibl, S | 1 |
| Patiou, P | 1 |
| Hunter, AM | 1 |
| Mora, E | 1 |
| Dimou, M | 1 |
| Jimenez Lorenzo, MJ | 1 |
| Melchardt, T | 1 |
| Egle, A | 2 |
| Viniou, AN | 1 |
| Patel, BJ | 1 |
| Arnan, M | 1 |
| Valent, P | 2 |
| Roubakis, C | 1 |
| Bernal Del Castillo, T | 1 |
| Galanopoulos, A | 1 |
| Calabuig Muñoz, M | 1 |
| Bonadies, N | 1 |
| Medina de Almeida, A | 1 |
| Cermak, J | 1 |
| Jerez, A | 1 |
| Montoro, MJ | 1 |
| Cortés, A | 1 |
| Avendaño Pita, A | 1 |
| Lopez Andrade, B | 1 |
| Hellstroem-Lindberg, E | 1 |
| Germing, U | 1 |
| Sekeres, MA | 1 |
| List, AF | 1 |
| Symeonidis, A | 1 |
| Sanz, GF | 1 |
| Larcher-Senn, J | 1 |
| Greil, R | 2 |
| Tremblay, D | 1 |
| Rippel, N | 1 |
| Feld, J | 1 |
| El Jamal, SM | 1 |
| Mascarenhas, J | 1 |
| Renneville, A | 1 |
| Patnaik, MM | 1 |
| Chan, O | 1 |
| Solary, E | 1 |
| Schwede, M | 1 |
| Gotlib, J | 1 |
| Shomali, W | 1 |
| Hilmi, M | 1 |
| Bally, C | 1 |
| Burns, R | 1 |
| Lorillon, G | 1 |
| Bergeron, A | 1 |
| Fenaux, P | 4 |
| Ades, L | 1 |
| Huemer, F | 1 |
| Weiss, L | 1 |
| Faber, V | 1 |
| Neureiter, D | 1 |
| Voskova, D | 1 |
| Zebisch, A | 1 |
| Burgstaller, S | 1 |
| Pichler, A | 1 |
| Stauder, R | 1 |
| Sperr, W | 1 |
| Lang, A | 1 |
| Pfeilstöcker, M | 1 |
| Machherndl-Spandl, S | 1 |
| Stampfl, M | 1 |
| Prada Garcia, C | 1 |
| Sanchez Sambucety, P | 1 |
| Rodriguez Prieto, MÁ | 1 |
| Liang, Y | 1 |
| Lu, RN | 1 |
| Wang, R | 1 |
| Zhang, JF | 1 |
| Su, W | 1 |
| Li, JY | 1 |
| Zhang, SJ | 1 |
| Lu, H | 1 |
| Imai, H | 1 |
| Matsumura, N | 1 |
| Yamazaki, Y | 1 |
| Kanayama, Y | 1 |
| Masuda, T | 1 |
| Kuwako, T | 1 |
| Kamide, Y | 1 |
| Tomizawa, T | 1 |
| Matsumoto, S | 1 |
| Mitsui, T | 1 |
| Kaira, K | 1 |
| Ono, A | 1 |
| Koga, Y | 1 |
| Shibusawa, N | 1 |
| Sunaga, N | 1 |
| Hisada, T | 1 |
| Yokoo, H | 1 |
| Yamada, M | 1 |
| Sunami, Y | 1 |
| Gotoh, A | 1 |
| Watanabe, N | 1 |
| Edahiro, Y | 1 |
| Hamano, Y | 1 |
| Harada, H | 1 |
| Komatsu, N | 1 |
| Huang, CT | 1 |
| Kuo, PH | 1 |
| Yao, M | 1 |
| Tsai, YJ | 1 |
| Yang, PC | 1 |
| Yamazaki, E | 1 |
| Kanai, M | 1 |
| Sakai, R | 1 |
| Sakamoto, H | 1 |
| Ishigatsubo, Y | 1 |
| Daskalakis, M | 1 |
| Mauritzson, N | 1 |
| Johansson, B | 1 |
| Bouabdallah, K | 1 |
| Onida, F | 1 |
| Kunzmann, R | 1 |
| Müller-Berndorff, H | 1 |
| Schmitt-Gräff, A | 1 |
| Lübbert, M | 1 |
| Otrock, ZK | 1 |
| Taher, AT | 1 |
| Mahfouz, RA | 1 |
| Makarem, JA | 1 |
| Shamseddine, AI | 1 |
| Aguilera Cros, C | 1 |
| Gutierrez, I | 1 |
| Gómez, JP | 1 |
| Alioglu, B | 1 |
| Demirhan, B | 1 |
| Ozyurek, E | 1 |
| Varan, B | 1 |
| Erbay, A | 1 |
| Ozbek, N | 1 |
| Wimazal, F | 1 |
| Baumgartner, C | 1 |
| Sonneck, K | 1 |
| Zauner, C | 1 |
| Geissler, P | 1 |
| Schur, S | 1 |
| Samorapoompichit, P | 1 |
| Müllauer, L | 1 |
| Födinger, M | 1 |
| Agis, H | 1 |
| Sperr, WR | 1 |
| Morschhauser, F | 1 |
| Wattel, E | 3 |
| Pagniez, D | 1 |
| Lovi, V | 1 |
| Rose, C | 1 |
| Bauters, F | 1 |
| Cambier, N | 1 |
| Menot, ML | 1 |
| Guerci, A | 2 |
| Chomienne, C | 1 |
| Hecquet, B | 1 |
| Economopoulos, T | 1 |
| Copplestone, A | 1 |
| Mahé, B | 1 |
| Couteaux, ME | 1 |
| Resegotti, L | 1 |
| Voglova, V | 1 |
| Foussard, C | 1 |
| Pegourié, B | 1 |
| Michaux, JL | 1 |
| Deconinck, E | 1 |
| Stoppa, AM | 1 |
| Mufti, G | 1 |
| Oscier, D | 1 |
| Muroi, K | 1 |
| Miyata, T | 1 |
| Saito, M | 1 |
| Hatake, K | 1 |
| Amemiya, Y | 1 |
| Miura, Y | 1 |
| Schiefke, I | 1 |
| Halm, U | 1 |
| Paasch, U | 1 |
| Pönisch, W | 1 |
| Berr, F | 1 |
| Mössner, J | 1 |
| Randi, ML | 1 |
| Fabris, F | 1 |
| Girolami, A | 1 |
| Kaya, H | 1 |
| Nakamura, S | 1 |
| Okafuji, K | 1 |
| Terasaki, Y | 1 |
| Maeno, K | 1 |
| Tanaka, N | 1 |
| Ohtake, S | 1 |
| Matsuda, T | 1 |
| Shen, Y | 1 |
| Xue, Y | 1 |
| Li, J | 1 |
| Guo, Y | 1 |
| Wu, Y | 1 |
| Pan, J | 1 |
| Bennett, JM | 1 |
| Provan, A | 1 |
| Majer, RV | 1 |
| Herbert, A | 1 |
| Smith, AG | 1 |
| Holcombe, RF | 1 |
| Treseler, PA | 1 |
| Rosenthal, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Phase III Study of Decitabine (DAC) With or Without Hydroxyurea (HY) Versus HY in Patients With Advanced Proliferative Chronic Myelomonocytic Leukemia (CMML)[NCT02214407] | Phase 3 | 170 participants (Actual) | Interventional | 2014-10-14 | Completed | ||
| Austrian Myeloid Registry[NCT04438889] | 3,000 participants (Anticipated) | Observational [Patient Registry] | 2020-07-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for hydroxyurea and Myelomonocytic Leukemia, Chronic
| Article | Year |
|---|---|
Proposals for Clinical Trials in Chronic Myelomonocytic Leukemia.
Topics: Hematologic Neoplasms; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Stem Cell Transplanta | 2023 |
Chronic myelomonocytic leukemia (CMML)-0 with pleural effusion as first manifestation: A case report.
Topics: Adult; Antineoplastic Agents; Azacitidine; Diagnosis, Differential; Drug Therapy, Combination; Femal | 2020 |
Contemporary Risk Stratification and Treatment of Chronic Myelomonocytic Leukemia.
Topics: Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Mut | 2021 |
Increasing recognition and emerging therapies argue for dedicated clinical trials in chronic myelomonocytic leukemia.
Topics: Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topi | 2021 |
Diagnosis and management of neutrophilic myeloid neoplasms.
Topics: Antineoplastic Agents; Disease Management; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyu | 2021 |
Chronic myelomonocytic leukaemia associated with acquired haemophilia A: case report and literature review.
Topics: Aged; Antineoplastic Agents; Coagulants; Factor VIII; Hematuria; Hemophilia A; Humans; Hydroxyurea; | 2015 |
Chronic myelomonocytic leukemia.
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Combined Modality Therapy; Humans; Hydroxyurea; | 2002 |
2 trials available for hydroxyurea and Myelomonocytic Leukemia, Chronic
| Article | Year |
|---|---|
All-trans retinoic acid in adult chronic myelomonocytic leukemia: results of a pilot study.
Topics: Aged; Antineoplastic Agents; Bone Marrow; Colony-Forming Units Assay; Female; Hematopoietic Stem Cel | 1996 |
A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Français des Myélodysplasies and European CMML Group.
Topics: Adult; Aged; Alopecia; Blood Cell Count; Cross-Over Studies; Etoposide; Female; Humans; Hydroxyurea; | 1996 |
24 other studies available for hydroxyurea and Myelomonocytic Leukemia, Chronic
| Article | Year |
|---|---|
Treatment options and survival in real life during the past three decades in patients with chronic myelomonocytic leukemia.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic | 2023 |
Sequential development of human herpes virus 8-positive diffuse large B-cell lymphoma and chronic myelomonocytic leukemia in a 59 year old female patient with hemoglobin SC disease.
Topics: Antisickling Agents; Cell Transformation, Neoplastic; Disease Progression; Fatal Outcome; Female; He | 2019 |
Successful treatment of chronic myelomonocytic leukaemia with hydroxycarbamide in a patient presenting with acute hypoxic respiratory failure due to COVID-19 pneumonia.
Topics: COVID-19; COVID-19 Drug Treatment; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Mid | 2020 |
Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study.
Topics: Aged; Antineoplastic Agents; Azacitidine; Female; Humans; Hydroxyurea; Kaplan-Meier Estimate; Leukem | 2021 |
Favorable evolution of lung interstitial disease in a patient with chronic myelomonocytic leukemia treated with azacitidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Combined Modality Therapy; Drug Resistance; Humans; Hy | 2018 |
Establishment and validation of a novel risk model for estimating time to first treatment in 120 patients with chronic myelomonocytic leukaemia.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, | 2018 |
[Cutaneous infiltratiton by chronic myelononocytic leukemia: presentation of three cases].
Topics: Aged; Antineoplastic Agents; Azacitidine; Cytarabine; Fatal Outcome; Humans; Hydroxyurea; Leukemia, | 2013 |
Hydroxyurea-induced Pneumonitis in a Patient with Chronic Myelomonocytic Leukemia: An Autopsy Case.
Topics: Aged, 80 and over; Autopsy; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Lung Diseases, I | 2015 |
[Chronic Myelomonocytic Leukemia with Myelofibrosis Resulting in Sudden Massive Pleural Effusion during Cytoreductive Therapy with Hydroxycarbamide].
Topics: Antineoplastic Agents; Cytoreduction Surgical Procedures; Drainage; Humans; Hydroxyurea; Leukemia, M | 2016 |
Pleural effusion heralds acute leukemic transformation of chronic myelomonocytic leukemia.
Topics: Blast Crisis; Bone Marrow; Disease Progression; Fatal Outcome; Female; Humans; Hydroxyurea; Leukemia | 2008 |
[Chronic myelomonocytic leukemia with pleural effusion as the first clinical sign].
Topics: Antineoplastic Agents; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukemic Infiltration | 2005 |
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 19; Cytarabine; Cytogenetic Anal | 2006 |
Acute tumor lysis syndrome secondary to hydroxycarbamide in chronic myelomonocytic leukemia.
Topics: Antineoplastic Agents; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Tu | 2006 |
Leukemic infiltration of the knee.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Humans; Hydroxyurea | 2006 |
Pulmonary hypertension in a child with juvenile myelomonocytic leukemia secondary to pulmonary leukemic cell infiltration.
Topics: Anti-Bacterial Agents; Child, Preschool; Combined Modality Therapy; Diagnostic Errors; Fatal Outcome | 2006 |
Mixed-lineage eosinophil/basophil crisis in MDS: a rare form of progression.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Basophils; Disease Progression; Eosinophils; | 2008 |
Glomerular injury in chronic myelomonocytic leukemia.
Topics: Aged; Amyloidosis; Etoposide; Female; Humans; Hydroxyurea; Kidney Diseases; Kidney Glomerulus; Leuke | 1995 |
Therapy-related chronic myelomonocytic leukaemia with bone marrow eosinophilia associated with der(11)t(1;11)(q21;q14).
Topics: Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Child; Chromosome Aberrations; Eosinophilia; Fa | 1996 |
[Pyoderma gangrenosum and portal vein thrombosis in a 33-year-old female patient].
Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents; Ascites; Azathioprine; Bone | 1999 |
Leukemia and myelodysplasia in patients with essential thrombocythemia treated with cytotoxic agents.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Busulfan; Female; Follow-Up Studies; Humans; | 1999 |
Trisomy 14 with thrombocytosis and monocytosis.
Topics: Aclarubicin; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agen | 2000 |
Pentasomy 8q resulting from duplication of isochromosome 8q in chronic myelomonocytic leukemia.
Topics: Aneuploidy; Chromosomes, Human, Pair 8; Cytogenetic Analysis; Fatal Outcome; Gene Duplication; Human | 2002 |
del(15)(q11q15) associated with transformation of chronic myelomonocytic leukemia.
Topics: Aged; Blood Transfusion; Chromosome Deletion; Chromosomes, Human, Pair 15; Humans; Hydroxyurea; Kary | 1991 |
Chronic myelomonocytic leukemia transformation in polycythemia vera.
Topics: Aged; Bone Marrow Examination; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukocyte Cou | 1991 |