hydroxyurea has been researched along with Muscle Contraction in 7 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A selective and potent 5-LO inhibitor, zileuton (N-1(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea, A-64077) was evaluated in models of airway anaphylaxis, where leukotrienes are a major component." | 7.69 | The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis. ( Bell, RL; Brooks, DW; Carter, GW; Malo, PE; Shaughnessy, TK; Summers, JB, 1994) |
| " A selective and potent 5-LO inhibitor, zileuton (N-1(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea, A-64077) was evaluated in models of airway anaphylaxis, where leukotrienes are a major component." | 3.69 | The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis. ( Bell, RL; Brooks, DW; Carter, GW; Malo, PE; Shaughnessy, TK; Summers, JB, 1994) |
| "Indomethacin treatment abolished the influence of the epithelium on ovalbumin-induced tracheal contraction." | 1.29 | Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips. ( Buckner, CK; Conklin, R; Doran, O; Fishleder, RI; Graziano, FM; Will, JA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinogradova, OO | 1 |
| Yanchuk, PI | 1 |
| Pasichnichenko, OM | 1 |
| Buckner, CK | 1 |
| Fishleder, RI | 1 |
| Conklin, R | 1 |
| Will, JA | 1 |
| Doran, O | 1 |
| Graziano, FM | 1 |
| Malo, PE | 2 |
| Bell, RL | 2 |
| Shaughnessy, TK | 2 |
| Summers, JB | 1 |
| Brooks, DW | 1 |
| Carter, GW | 2 |
| Heaslip, RJ | 1 |
| Grimes, D | 1 |
| Berkenkopf, JW | 1 |
| Ilsemann, BA | 1 |
| Sickels, BD | 1 |
| Weichman, BM | 1 |
| Harris, RR | 1 |
| Bouska, JB | 1 |
| Hulkower, KI | 1 |
| Brooks, CD | 1 |
| Noonan, TC | 1 |
| Jamieson-Leclercq, T | 1 |
| Desai, SN | 1 |
| Wong, WS | 1 |
| Bendele, AM | 1 |
| Fleisch, JH | 1 |
7 other studies available for hydroxyurea and Muscle Contraction
| Article | Year |
|---|---|
[ROLE OF THROMBOXANE AND LEUKOTRIENES IN MECHANISMS OF CONTRACTILE REACTIONS OF PORTAL VEIN, INDUCED BY ACETYLCHLINE AND PHENYLEPHRINE].
Topics: Acetylcholine; Animals; Endothelium, Vascular; Female; Hydroxyurea; In Vitro Techniques; Leukotriene | 2015 |
Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips.
Topics: Animals; Epithelium; Female; Guinea Pigs; Histamine Release; Hydroxyurea; In Vitro Techniques; Indaz | 1993 |
The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoconstriction; Disease Models, | 1994 |
Anti-leukotriene effects of WY-50,295 tromethamine in isolated guinea pig pulmonary tissues.
Topics: Acetophenones; Animals; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Indoles; Leukotriene Antagoni | 1993 |
ABT-761 attenuates bronchoconstriction and pulmonary inflammation in rodents.
Topics: Animals; Bronchoconstriction; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Humans; Hydroxyurea; In V | 1997 |
Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction in vitro.
Topics: Animals; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Indoles; Leukotriene B4; Lipoxygenase Inhibi | 1992 |
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Intera | 1992 |