hydroxyurea has been researched along with Methemoglobinemia in 4 studies
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Timed-pregnant Fischer 344 rats were dosed by gavage with aniline hydrochloride (10, 30, or 100 mg/kg/day), a positive control agent (hydroxyurea, 200 mg/kg/day), or vehicle (distilled water) on gestational days (gd) 7 through 20 or gd 7 through parturition." | 1.27 | Teratologic and postnatal evaluation of aniline hydrochloride in the Fischer 344 rat. ( Ledoux, TA; Marks, TA; Paschke, LL; Price, CJ; Reel, JR; Tyl, RW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boucher, AA | 1 |
| Gurunathan, A | 1 |
| Taylor, JM | 1 |
| Ricci, KW | 1 |
| Vadivelu, S | 1 |
| Quinn, CT | 1 |
| Wray, JD | 1 |
| Bates, N | 1 |
| Price, CJ | 1 |
| Tyl, RW | 1 |
| Marks, TA | 1 |
| Paschke, LL | 1 |
| Ledoux, TA | 1 |
| Reel, JR | 1 |
4 other studies available for hydroxyurea and Methemoglobinemia
| Article | Year |
|---|---|
Hemoglobin Southampton complicated by cerebral ischemia, moyamoya, and hydroxyurea-induced methemoglobinemia.
Topics: Aspirin; Brain Ischemia; Child; Female; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Hydroxyur | 2019 |
Methaemoglobinaemia caused by hydroxycarbamide (hydroxyurea) ingestion in a dog.
Topics: Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Granulocyte Colony-Stimulating Factor; Hemat | 2008 |
Hydroxycarbamide (hydroxyurea) toxicity in dogs.
Topics: Animals; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyurea; Hypox | 2008 |
Teratologic and postnatal evaluation of aniline hydrochloride in the Fischer 344 rat.
Topics: Abnormalities, Drug-Induced; Aniline Compounds; Animals; Animals, Newborn; Blood; Body Weight; Eryth | 1985 |