hydroxyurea has been researched along with Lymphoma in 49 studies
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the cell cycle regulation of deoxyribonucleoside triphosphate (dNTP) metabolism in hydroxyurea-resistant (HYUR) murine S49 T-lymphoma cell lines." | 7.67 | Deoxyribonucleotide metabolism and cyclic AMP resistance in hydroxyurea-resistant S49 T-lymphoma cells. ( Albert, DA; Gudas, LJ; Nodzenski, E, 1987) |
| "Hydroxyurea-resistant S49 T-lymphoma cells have increased ribonucleotide reductase activity and deoxyribonucleoside triphosphate pools when compared with wild-type cultures." | 7.67 | Deoxyadenosine toxicity and cell cycle arrest in hydroxyurea-resistant S49 T-lymphoma cells. ( Albert, DA; Nodzenski, E, 1988) |
| "The association between DNA precursor synthesis, cell cycle perturbations, and cell death caused by the anticancer drug hydroxyurea was investigated in mouse and human T-lymphoma cells." | 7.67 | Hydroxyurea-induced cell death as related to cell cycle in mouse and human T-lymphoma cells. ( Eriksson, S; Skog, S; Tribukait, B; Wallström, B, 1987) |
| "Chromosomal aberrations and dihydrofolate reductase gene amplification are observed in L5178Y mouse lymphoma cells after treatment with hydroxyurea." | 7.67 | Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. ( Hill, AB; Schimke, RT, 1985) |
| "An analysis of the risk of progression towards leukemia, carcinoma and myelofibrosis was performed in 93 patients treated by 32P alone (PVSG protocols) since 1970-1979, 395 patients over the age of 65 years treated by 32P with or without maintenance therapy using hydroxyurea (French protocol) since 1980-1994, and 202 patients under the age of 65 treated by either hydroxyurea or pipobroman since 1980." | 6.18 | Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias". ( Dresch, C; Echard, M; Goguel, A; Grange, MJ; Lejeune, F; Najean, Y; Rain, JD, 1996) |
| "Gallium nitrate inhibits the growth of various lymphoma cell lines in vitro and exhibits antitumor activity in patients with lymphoma." | 4.82 | Apoptotic mechanisms of gallium nitrate: basic and clinical investigations. ( Chitambar, CR, 2004) |
| " Using cDNA microarrays, we compared the gene expression profiles produced in mouse lymphoma cells by three genotoxic compounds, hydroxyurea (a carcinogen), p-anisidine (a noncarcinogen), and paclitaxel (carcinogenicity unknown)." | 3.72 | cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and p-anisidine, genotoxic compounds with differing tumorigenicity results. ( Chung, MK; Han, SS; Kim, EJ; Kim, JE; Kim, SN; Koh, WS; Kwon, J; Lee, M; Song, CW, 2003) |
| " We recently observed that some S49 mouse T lymphoma cell lines selected for hydroxyurea resistance were not arrested in G1 by cyclic AMP." | 3.67 | M2 subunit of ribonucleotide reductase is a target of cyclic AMP-dependent protein kinase. ( Albert, DA; Nodzenski, E, 1989) |
| "We investigated the cell cycle regulation of deoxyribonucleoside triphosphate (dNTP) metabolism in hydroxyurea-resistant (HYUR) murine S49 T-lymphoma cell lines." | 3.67 | Deoxyribonucleotide metabolism and cyclic AMP resistance in hydroxyurea-resistant S49 T-lymphoma cells. ( Albert, DA; Gudas, LJ; Nodzenski, E, 1987) |
| "Hydroxyurea-resistant S49 T-lymphoma cells have increased ribonucleotide reductase activity and deoxyribonucleoside triphosphate pools when compared with wild-type cultures." | 3.67 | Deoxyadenosine toxicity and cell cycle arrest in hydroxyurea-resistant S49 T-lymphoma cells. ( Albert, DA; Nodzenski, E, 1988) |
| "The association between DNA precursor synthesis, cell cycle perturbations, and cell death caused by the anticancer drug hydroxyurea was investigated in mouse and human T-lymphoma cells." | 3.67 | Hydroxyurea-induced cell death as related to cell cycle in mouse and human T-lymphoma cells. ( Eriksson, S; Skog, S; Tribukait, B; Wallström, B, 1987) |
| "Chromosomal aberrations and dihydrofolate reductase gene amplification are observed in L5178Y mouse lymphoma cells after treatment with hydroxyurea." | 3.67 | Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. ( Hill, AB; Schimke, RT, 1985) |
| "From 23 patients with advanced non-Hodgkin lymphomas of a high malignancy 11 received a therapy with CVPP scheme; 2 of them came into a complete remission and 3 of them into a partial one." | 2.65 | [The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study]. ( Anger, G; Fink, R; Höche, D, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (83.67) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 4 (8.16) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Sekhri, R | 1 |
| Sadjadian, P | 1 |
| Becker, T | 1 |
| Kolatzki, V | 1 |
| Huenerbein, K | 1 |
| Meixner, R | 1 |
| Marchi, H | 1 |
| Wallmann, R | 1 |
| Fuchs, C | 1 |
| Griesshammer, M | 1 |
| Wille, K | 1 |
| Yasuda, H | 1 |
| Tsutsui, M | 1 |
| Ota, Y | 1 |
| Misawa, K | 1 |
| Gotoh, A | 1 |
| Hamano, Y | 1 |
| Komatsu, N | 1 |
| Yong, KL | 1 |
| Fahey, A | 1 |
| Pizzey, A | 1 |
| Linch, DC | 1 |
| Lee, M | 1 |
| Kwon, J | 1 |
| Kim, SN | 1 |
| Kim, JE | 1 |
| Koh, WS | 1 |
| Kim, EJ | 1 |
| Chung, MK | 1 |
| Han, SS | 1 |
| Song, CW | 1 |
| DAVIS, P | 1 |
| SAMUELS, ML | 1 |
| HOWE, CD | 1 |
| Chitambar, CR | 1 |
| Höche, D | 1 |
| Fink, R | 1 |
| Anger, G | 1 |
| Caras, IW | 1 |
| Jones, T | 1 |
| Eriksson, S | 3 |
| Martin, DW | 1 |
| Pfeifle, CE | 1 |
| Howell, SB | 1 |
| Abe, I | 1 |
| Saito, S | 1 |
| Hori, K | 1 |
| Suzuki, M | 1 |
| Sato, H | 1 |
| van Leeuwen-Stok, AE | 1 |
| Schuurhuis, GJ | 1 |
| Dräger, AM | 1 |
| Visser-Platier, AW | 1 |
| Teule, GJ | 1 |
| Huijgens, PC | 1 |
| Najean, Y | 1 |
| Rain, JD | 1 |
| Dresch, C | 1 |
| Goguel, A | 1 |
| Lejeune, F | 1 |
| Echard, M | 1 |
| Grange, MJ | 1 |
| Montefusco, E | 1 |
| Fazi, F | 1 |
| Cordone, I | 1 |
| Ariola, C | 1 |
| Nanni, M | 1 |
| Spadea, A | 1 |
| Spiriti, MA | 1 |
| Fenu, S | 1 |
| Mandelli, F | 1 |
| Petti, MC | 1 |
| Lowe, JK | 1 |
| Henderson, JF | 1 |
| Kornacka, L | 2 |
| Sawecka, J | 1 |
| Malec, J | 2 |
| Maruyama, Y | 2 |
| Raju, MR | 1 |
| Bains, E | 1 |
| Jett, J | 1 |
| Klein, HO | 1 |
| Adler, D | 1 |
| Doering, M | 1 |
| Klein, PJ | 1 |
| Lennartz, KJ | 1 |
| Wollner, N | 3 |
| Lieberman, P | 1 |
| Exelby, P | 2 |
| D'angio, G | 2 |
| Burchenal, J | 1 |
| Fang, S | 1 |
| Murphy, ML | 3 |
| Burchenal, JH | 2 |
| Lieberman, PH | 2 |
| Exelby, PR | 1 |
| D'Angio, GJ | 1 |
| Wojnarowska, M | 1 |
| Albert, DA | 4 |
| Nodzenski, E | 3 |
| Froom, P | 1 |
| Quitt, M | 1 |
| Aghai, E | 1 |
| Gudas, LJ | 2 |
| Skog, S | 2 |
| Tribukait, B | 2 |
| Wallström, B | 2 |
| Gasser, AB | 1 |
| Steward, WP | 1 |
| Wagstaff, J | 1 |
| Scarffe, JH | 1 |
| Crowther, D | 1 |
| Hill, AB | 1 |
| Schimke, RT | 1 |
| Lehmann, AR | 2 |
| Kirk-Bell, S | 1 |
| Shall, S | 1 |
| Whish, WJ | 1 |
| Karran, P | 1 |
| Patel, D | 1 |
| Fox, M | 4 |
| Fox, BW | 3 |
| Carter, SK | 1 |
| Cikes, M | 2 |
| Klein, G | 2 |
| Friberg, S | 1 |
| Brunning, RD | 1 |
| Lee, TC | 1 |
| Sullivan, S | 1 |
| Ariel, IM | 1 |
| Mathé, G | 1 |
| Schneider, M | 1 |
| Schwarzenberg, L | 1 |
| Cattan, A | 1 |
| Amiel, JL | 1 |
| Schlumberger, JR | 1 |
| Scherer, E | 1 |
| Rassow, J | 1 |
| Mauro, F | 2 |
| Madoc-Jones, H | 2 |
| Ayad, SR | 2 |
3 reviews available for hydroxyurea and Lymphoma
| Article | Year |
|---|---|
Apoptotic mechanisms of gallium nitrate: basic and clinical investigations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; | 2004 |
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies | 1996 |
An overview of the status of the nitrosoureas in other tumors.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Carcinoma, Br | 1973 |
3 trials available for hydroxyurea and Lymphoma
| Article | Year |
|---|---|
[The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study].
Topics: Bleomycin; Cell Division; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Hodgkin D | 1980 |
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies | 1996 |
Treatment of relapsed non-Hodgkin's lymphoma with a combination of hydroxyurea, ifosfamide, and etoposide.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; E | 1985 |
44 other studies available for hydroxyurea and Lymphoma
| Article | Year |
|---|---|
Ruxolitinib-treated polycythemia vera patients and their risk of secondary malignancies.
Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Hydroxyurea; Incidence; Janus Kin | 2021 |
Blastic plasmacytoid dendritic cell neoplasm accompanied by autoimmune hemolytic anemia achieving complete remission with hydroxyurea and steroids.
Topics: Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Drug Therapy, Combination; | 2016 |
Influence of cell cycling and cell division on transendothelial migration of CD34+ cells.
Topics: Adult; Antigens, CD34; Biomarkers; Bone and Bones; Cell Adhesion; Cell Movement; Cells, Cultured; Ch | 2002 |
cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and p-anisidine, genotoxic compounds with differing tumorigenicity results.
Topics: Aniline Compounds; Animals; DNA Damage; Gene Expression Profiling; Hydroxyurea; Lymphoma; Mice; Olig | 2003 |
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MULTIPLE MYELOMA AND LYMPHOMA.
Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Hydroxyurea; Leukopenia; Lymphoma; Lymphoma, L | 1964 |
RENAL ABNORMALITIES INDUCED BY HYDROXYUREA (NSC-32065).
Topics: Antineoplastic Agents; Blood; Hematologic Diseases; Hematuria; Hydroxyurea; Kidney Diseases; Kidney | 1964 |
Direct photoaffinity labeling of the catalytic site of mouse ribonucleotide reductase by CDP.
Topics: Affinity Labels; Animals; Cytidine Diphosphate; Cytosine Nucleotides; Deoxyribonucleotides; Hydroxyu | 1983 |
Phase I trial of cytarabine and hydroxyurea.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Child; Cy | 1983 |
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Division; Cell Line; Cells, Cultured | 1982 |
Effect of modulation of the transferrin receptor on gallium-67 uptake and cytotoxicity in lymphoma cell lines.
Topics: Antineoplastic Agents; Biological Transport; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cy | 1996 |
Molecular remission following high-dose hydroxyurea and fludarabine plus cytarabine in a patient with simultaneous acute myeloid leukemia and low-grade lymphoma.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Leuk | 2001 |
Enhancement by caffeine of the growth inhibitory effects of antimetabolites in lymphoma L5178Y cells.
Topics: Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Deoxyadenosines; Drug Synergism; Hydroxyu | 1977 |
Comparison of hydroxyurea and excess thymidine as synchronizing agents in cultures of L5178Y mouse lymphoma cells.
Topics: Animals; Carbon Radioisotopes; Cell Cycle; Cell Membrane Permeability; Cells, Cultured; DNA, Neoplas | 1977 |
Study of in vivo tumor state and response to therapy by analysis of DNA distribution.
Topics: Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; DNA, Neoplasm; Female; Hydroxyurea; Kineti | 1976 |
Investigations on pharmacologic induction of partial synchronization of tumor cell proliferation: its relevance for cytostatic therapy.
Topics: Adolescent; Adult; Aged; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cyclophosphamide; Drug Ad | 1976 |
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosp | 1975 |
Non-Hodgkin's lymphoma in children.
Topics: Adolescent; Asparaginase; Bone Marrow; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cycloph | 1975 |
Synchronization of L5178Y cells by treatment with hydroxyurea.
Topics: Animals; Depression, Chemical; DNA; Hydroxyurea; Leukemia, Experimental; Lymphoma; Mice; Mitotic Ind | 1975 |
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphami | 1976 |
M2 subunit of ribonucleotide reductase is a target of cyclic AMP-dependent protein kinase.
Topics: Animals; Cell Line; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Hydroxyurea; Lymphoma; Macromol | 1989 |
The mean leukocyte myeloperoxidase index in hematological patients.
Topics: Hematologic Diseases; Hospitalization; Humans; Hydroxyurea; Leukocytes; Lymphoma; Lymphoma, Non-Hodg | 1989 |
Characterization of hydroxyurea (HYU) resistant S49 T lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Cyclic AMP; Deoxyribonucleotides; Drug Resistance; Hydroxyurea; Lymp | 1986 |
Deoxyribonucleotide metabolism and cyclic AMP resistance in hydroxyurea-resistant S49 T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Cyclic AMP; Deoxyribonucleotides; Drug Resistance; Hydroxyurea; Lymp | 1987 |
Deoxyadenosine toxicity and cell cycle arrest in hydroxyurea-resistant S49 T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Deoxyadenosines; Drug Resistance; Hydroxyurea; Lymphoma; Ribonucleos | 1988 |
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxycytidine Kinase; Deoxycytosine Nucleo | 1987 |
Hydroxyurea-induced cell death as related to cell cycle in mouse and human T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Survival; Deoxyribonucleosides; Humans; Hydroxyurea; Lymphoma; Mice; T-Lym | 1987 |
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations.
Topics: Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA; DNA Replication; Drug Resistan | 1985 |
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.
Topics: Adenosine Diphosphate; Animals; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin; | 1974 |
The repair of methyl methanesulphonate-induced lesions in the DNA of a murine lymphoma cell.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Cytarabine; Deoxycytidine; DNA Repair; DNA Rep | 1973 |
Hydroxyurea its value in 50 cases of advanced cancers.
Topics: Adolescent; Adult; Humans; Hydroxyurea; Leukemia, Myeloid; Lymphoma; Male; Middle Aged; Mouth Neopla | 1973 |
Repair replication in x-irradiated lymphoma cells in vitro.
Topics: Amylases; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; DNA Repair; DNA Replication; | 1973 |
Repair replication after U.V.-irradiation in rodent cell-lines of different sensitivity.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; DNA Repair; DN | 1973 |
Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Cell Membrane; Cells, | 1972 |
Quantitative studies of antigen expression in cultured murine lymphoma cells. II. Cell-surface antigens in synchronized cultures.
Topics: Absorption; Animals; Antibody Specificity; Antigen-Antibody Reactions; Antigens, Neoplasm; Antigens, | 1972 |
The effects of leukemia and lymphoma chemotherapy on hematopoietic cells.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Asparaginase; Cell Division; Daunorubicin | 1973 |
Age cohort variation of tumor cells.
Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma; | 1973 |
Anticancer therapy with hydrea: comparative study of daily vs. intermittent oral dosage.
Topics: Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Dr | 1974 |
[Personal experience on the chemotherapy of leukemias and hematosarcomas].
Topics: Antineoplastic Agents; Drug Synergism; Hodgkin Disease; Humans; Hydrazines; Hydroxyurea; Leukemia; L | 1968 |
[Basic principles of percutaneous radiotherapy in cervical lymph node metastases].
Topics: Carcinoma, Squamous Cell; Cesium Isotopes; Cobalt Isotopes; Electrons; Fluorouracil; Head and Neck N | 1971 |
Postreplication repair of DNA in ultraviolet-irradiated mammalian cells.
Topics: Animals; Bromodeoxyuridine; Bromouracil; Cell Line; Centrifugation, Density Gradient; DNA; DNA Repai | 1972 |
Age response to x-radiation of murine lymphoma cells synchronized in vivo.
Topics: Aging; Animals; Biological Assay; Cell Division; Cell Line; Clone Cells; HeLa Cells; Hydroxyurea; Ly | 1969 |
The implication of repair processes in the mechanism of DNA integration by lymphoma cells.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Culture Techniques; DNA; DNA, Neoplasm; Hydroxyur | 1969 |
Characteristics of "repair synthesis" in x-irradiated P388F lymphoma cells.
Topics: Autoradiography; Cell Line; Centrifugation, Density Gradient; Cesium; Culture Techniques; Deoxyuridi | 1970 |
Age responses to x rays, Vinca alkaloids, and hydroxyurea of murine lymphoma cells synchronized in vivo.
Topics: Animals; Bone Marrow; Cricetinae; Femoral Neoplasms; Hydroxyurea; Lymphoma; Mice; Neoplasms, Experim | 1970 |