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hydroxyurea and Leukopenia

hydroxyurea has been researched along with Leukopenia in 27 studies

Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).

Research Excerpts

ExcerptRelevanceReference
" levofolinic acid and oral hydroxyurea on a weekly schedule is well tolerated by the vast majority of patients with locally advanced and/or metastatic carcinoma of the pancreas or the gallbladder."9.08Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.). ( Colucci, G; Fortunato, S; Gebbia, N; Gebbia, V; Giotta, F; Giuseppe, S; Majello, E; Pezzella, G; Riccardi, F; Testa, A, 1996)
"Hydroxyurea is an effective agent in the treatment of PV, but continued assessment of its mutagenic potential is necessary."5.27Treatment of polycythemia vera with hydroxyurea. ( Berk, PD; Donovan, PB; Goldberg, JD; Kaplan, ME; Knospe, WH; Laszlo, J; Mack, K; Najean, Y; Silberstein, EB; Tatarsky, I, 1984)
" levofolinic acid and oral hydroxyurea on a weekly schedule is well tolerated by the vast majority of patients with locally advanced and/or metastatic carcinoma of the pancreas or the gallbladder."5.08Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.). ( Colucci, G; Fortunato, S; Gebbia, N; Gebbia, V; Giotta, F; Giuseppe, S; Majello, E; Pezzella, G; Riccardi, F; Testa, A, 1996)
"Hydroxyurea is an effective agent in the treatment of PV, but continued assessment of its mutagenic potential is necessary."1.27Treatment of polycythemia vera with hydroxyurea. ( Berk, PD; Donovan, PB; Goldberg, JD; Kaplan, ME; Knospe, WH; Laszlo, J; Mack, K; Najean, Y; Silberstein, EB; Tatarsky, I, 1984)
"mm."1.25Hydroxyurea in stage D carcinoma of the prostate: a pilot study. ( Cromie, W; Lerner, H; Longo, S; Malloy, T, 1975)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199023 (85.19)18.7374
1990's2 (7.41)18.2507
2000's0 (0.00)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gülseren, D1
Elçin, G1
Büyükaşık, Y1
Alvarez-Larrán, A1
Kerguelen, A1
Hernández-Boluda, JC1
Pérez-Encinas, M1
Ferrer-Marín, F1
Bárez, A1
Martínez-López, J1
Cuevas, B1
Mata, MI1
García-Gutiérrez, V1
Aragües, P1
Montesdeoca, S1
Burgaleta, C1
Caballero, G1
Hernández-Rivas, JA1
Durán, MA1
Gómez-Casares, MT1
Besses, C1
GRIFFITH, KM1
BLOEDOW, CE1
HOWE, CD1
SAMUELS, ML2
DAVIS, P1
Cassileth, PA1
Hyman, GA1
Vogl, SE1
Camacho, F1
Kaplan, BH1
Lerner, H2
Cinberg, J1
Stephens, RL1
Vaughn, C1
Lane, M1
Costanzi, J1
O'Bryan, R1
Balcerzak, SP1
Levin, H1
Frank, J1
Coltman, CA1
Donovan, PB1
Kaplan, ME1
Goldberg, JD1
Tatarsky, I1
Najean, Y1
Silberstein, EB1
Knospe, WH1
Laszlo, J1
Mack, K1
Berk, PD1
Gebbia, V1
Majello, E1
Testa, A1
Pezzella, G1
Giuseppe, S1
Giotta, F1
Riccardi, F1
Fortunato, S1
Colucci, G1
Gebbia, N1
Bureau, MF1
De Castro, CM1
Cortese, C1
Bachelet, M1
Vargaftig, BB1
Hansen, HH1
Selawry, OS1
Simon, R1
Carr, DT1
van Wyk, CE1
Tucker, RD1
Sealy, R1
Alberto, P1
Barrelet, L1
Chapuis, B1
Garcia, B1
Brincker, H1
Malloy, T1
Cromie, W1
Longo, S1
Lokich, JJ1
Pitman, SW1
Skarin, AT1
Engelhardt, B1
Sandberg, K1
Bratton, D1
Van den Abbeele, A1
Grogaard, J1
Hellerqvist, C1
Sundell, H1
Landgren, RC1
Hussey, DH1
Barkley, HT1
Moschella, SL1
Greenwald, MA1
Spier, S1
Solomon, LM1
Esterly, NB1
Fried, W1
Hellmann, K1
Nissen, NI1
Dano, K1
Slack, NM1
Jones, R1
Creasey, WA1
Capizzi, RL1
DeConti, RC1
Gottlieb, JA1
Frei, E1
Luce, JK1
Lerner, HJ1
Beckloff, GL1
Godwin, MC1

Reviews

1 review available for hydroxyurea and Leukopenia

ArticleYear
[New principles of treatment in acute leukemia].
    Ugeskrift for laeger, 1970, Apr-30, Volume: 132, Issue:18

    Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide;

1970

Trials

7 trials available for hydroxyurea and Leukopenia

ArticleYear
Adriamycin and cyclophosphamide versus hydroxyurea in advanced prostatic cancer. A randomized Southwest Oncology Group study.
    Cancer, 1984, Feb-01, Volume: 53, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Do

1984
Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.).
    Cancer, 1996, Sep-15, Volume: 78, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplast

1996
Combination chemotherapy of advanced lung cancer: a randomized trial.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell;

1976
A combination of adriamycin, CCNU and hydroxyurea in the treatment of disseminated bronchogenic carcinoma.
    European journal of cancer, 1975, Volume: 11, Issue:11

    Topics: Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Drug Thera

1975
Split-course irradiation compared to split-course irradiation plus hydroxyurea in inoperable bronchogenic carcinoma--a randomized study of 53 patients.
    Cancer, 1974, Volume: 34, Issue:5

    Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Esophagitis

1974
Single reversal trial of hydroxyurea (NSC-32065) in 91 patients with advanced cancer.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:1

    Topics: Anemia; Asparaginase; Azaserine; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Drug

1970
Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065).
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:3

    Topics: Adult; Aged; Blood Urea Nitrogen; Chondrosarcoma; Clinical Trials as Topic; Depression, Chemical; DN

1970

Other Studies

19 other studies available for hydroxyurea and Leukopenia

ArticleYear
Severe cytopenia related with the concomitant use of imiquimod and hydroxyurea.
    Dermatologic therapy, 2019, Volume: 32, Issue:6

    Topics: Adjuvants, Immunologic; Antineoplastic Agents; Humans; Hydroxyurea; Imiquimod; Leukopenia; Lymphopen

2019
Frequency and prognostic value of resistance/intolerance to hydroxycarbamide in 890 patients with polycythaemia vera.
    British journal of haematology, 2016, Volume: 172, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Resistance; Drug Tolerance; Female; Humans; Hydroxy

2016
HYDROXYUREA (NSC-32065): RESULTS OF A PHASE I STUDY.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Aplastic; Antineoplastic Agents; Drug Therapy; Hydroxyurea; Leukopenia; Statistics a

1964
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MISCELLANEOUS TUMORS.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Carcinom

1964
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: UROLOGIC AND GYNECOLOGIC NEOPLASMS.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Adenocarcinoma; Anemia; Anemia, Aplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Ther

1964
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MULTIPLE MYELOMA AND LYMPHOMA.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Hydroxyurea; Leukopenia; Lymphoma; Lymphoma, L

1964
Treatment of malignant melanoma with hydroxyurea.
    Cancer research, 1967, Volume: 27, Issue:10

    Topics: Adult; Aged; Female; Humans; Hydroxyurea; Leukopenia; Male; Melanoma; Middle Aged; Neoplasm Metastas

1967
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
    Cancer, 1983, Dec-01, Volume: 52, Issue:11

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug

1983
Treatment of polycythemia vera with hydroxyurea.
    American journal of hematology, 1984, Volume: 17, Issue:4

    Topics: Acute Disease; Aged; Bone Marrow; Female; Humans; Hydroxyurea; Leukemia; Leukopenia; Male; Middle Ag

1984
5-Lipoxygenase and endotoxin-induced microvascular albumin exchanges and leucocyte recruitment in guinea-pig lungs.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Bronchopulmonary Sequestration; Cell Count; C

1997
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
    Scandinavian journal of haematology, 1975, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; D

1975
Hydroxyurea in stage D carcinoma of the prostate: a pilot study.
    The Journal of urology, 1975, Volume: 114, Issue:3

    Topics: Adenocarcinoma; Aged; Anemia; Bone Neoplasms; Chlorotrianisene; Estrogens; Humans; Hydroxyurea; Leuk

1975
Combined 5-fluorouracil and hydroxyurea therapy for gastrointestinal cancer.
    Oncology, 1975, Volume: 32, Issue:1

    Topics: Administration, Oral; Ataxia; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointe

1975
The role of granulocytes in the pulmonary response to group B streptococcal toxin in young lambs.
    Pediatric research, 1987, Volume: 21, Issue:2

    Topics: Animals; Capillary Permeability; Granulocytes; Hydroxyurea; Hypertension, Pulmonary; Leukopenia; Lun

1987
Psoriasis with hydroxyurea. An 18-month study of 60 patients.
    Archives of dermatology, 1973, Volume: 107, Issue:3

    Topics: Adult; Aged; Anemia; Chemical and Drug Induced Liver Injury; Drug Resistance; Female; Humans; Hydrox

1973
Hydroxyurea and macrocytosis.
    The British journal of dermatology, 1973, Volume: 89, Issue:2

    Topics: Adult; Anemia, Macrocytic; Bone Marrow; Female; Folic Acid; Humans; Hydroxyurea; Leukopenia; Male; M

1973
Investigational drugs for the treatment of malignant melanoma.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:2

    Topics: Alkylating Agents; Amides; Anorexia Nervosa; Antineoplastic Agents; Cyclophosphamide; Dactinomycin;

1974
Dose-schedule studies with hydroxyurea (NSC-32065) in malignant melanoma.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Administration, Oral; Adult; Amides; Female; Humans; Hydroxyurea; Imidazoles; Injections, Intravenou

1971
Phase II study of hydroxyurea administered intermittently in malignant melanoma.
    The American surgeon, 1970, Volume: 36, Issue:8

    Topics: Adult; Aged; Chronic Disease; Female; Humans; Hydroxyurea; Leukocyte Count; Leukopenia; Male; Melano

1970