hydroxyurea has been researched along with Leukemia L5178 in 8 studies
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cells were dosed for 4 hr and harvested immediately at the end of the treatment or after a 20-hr recovery period." | 1.33 | Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea. ( Aardema, MJ; Boitier, E; Carr, GJ; Flor, M; Hu, T; Jefferson, F; Le Fèvre, AC; Marchandeau, JP; Müller, A; Thybaud, V, 2005) |
| "Supravital staining of lysosomal membranes with euchrysine was employed to study hydroxyurea (HU)-induced side toxic effects in L5178Y lymphoblasts in culture." | 1.27 | Alteration in lysosome supravital staining as a marker of hydroxyurea-induced cytotoxicity and its modification by radical scavengers in L5178Y cells in culture. ( Grabarczyk, M; Kwiatkowska, J; Malec, J; Przybyszewski, WM; Sitarska, E, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Selassie, CD | 1 |
| Hansch, C | 1 |
| Khwaja, TA | 1 |
| Dias, CB | 1 |
| Pentecost, S | 1 |
| Müller, A | 1 |
| Boitier, E | 1 |
| Hu, T | 1 |
| Carr, GJ | 1 |
| Le Fèvre, AC | 1 |
| Marchandeau, JP | 1 |
| Flor, M | 1 |
| Jefferson, F | 1 |
| Aardema, MJ | 1 |
| Thybaud, V | 1 |
| Grabarczyk, M | 1 |
| Przybyszewski, WM | 2 |
| Kwiatkowska, J | 1 |
| Sitarska, E | 1 |
| Malec, J | 5 |
| Bellamy, AS | 1 |
| Hill, BT | 1 |
| Kornacka, L | 1 |
| Sawecka, J | 3 |
| Gołos, B | 1 |
| Golos, B | 1 |
| Czartoryska, B | 1 |
8 other studies available for hydroxyurea and Leukemia L5178
| Article | Year |
|---|---|
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; | 1984 |
Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea.
Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Clinical Laboratory Technique | 2005 |
Alteration in lysosome supravital staining as a marker of hydroxyurea-induced cytotoxicity and its modification by radical scavengers in L5178Y cells in culture.
Topics: Animals; Cells, Cultured; Free Radicals; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Lysoso | 1983 |
Murine L5178Y cells resulting in altered drug sensitivities from fractionated radiation exposure in vitro.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etop | 1984 |
Differential cell-cycle-dependent inhibition of DNA synthesis by hydroxyurea and cytosine arabinoside in cultured L5178Y mouse lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Cytarabine; DNA, Neoplasm; Hydroxyurea; Leukemia L5178; Leukemia, Ex | 1979 |
Modification by caffeine of acute cytotoxic response of cultured L5178Y cells to hydroxyurea treatment.
Topics: Animals; Caffeine; Cell Division; Cell Survival; DNA Repair; DNA, Neoplasm; Drug Synergism; Hydroxyu | 1987 |
Mechanism of unbalanced growth-induced cell damage. II. A probable relationship between unbalanced growth, DNA breakage and cell death.
Topics: Animals; Cell Division; Cell Survival; DNA Damage; DNA Replication; Endodeoxyribonucleases; Hydroxyu | 1986 |
Effect of hydroxyurea treatment on lysosomal membrane stability and enzyme latency in L5178Y cells in culture.
Topics: Acid Phosphatase; Animals; Catalase; Cell Line; Hexosaminidases; Hydroxyurea; Intracellular Membrane | 1986 |