Page last updated: 2024-10-28

hydroxyurea and Injury, Ischemia-Reperfusion

hydroxyurea has been researched along with Injury, Ischemia-Reperfusion in 7 studies

Research Excerpts

ExcerptRelevanceReference
" The participation of nitric oxide (NO) in oxidative reactions causes a reduction in NO bioavailability and contributes to vascular dysfunction in SCD."2.44Redox-dependent impairment of vascular function in sickle cell disease. ( Aslan, M; Freeman, BA, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, F1
Soni, H1
Pressly, JD1
Adebiyi, A1
Connes, P1
Machado, R1
Hue, O1
Reid, H1
Patel, NS1
Cuzzocrea, S1
Chatterjee, PK1
Di Paola, R1
Sautebin, L1
Britti, D1
Thiemermann, C1
Aslan, M1
Freeman, BA1
Mangino, MJ1
Murphy, MK1
Anderson, CB1
Su, M1
Chi, EY1
Bishop, MJ1
Henderson, WR1
Dolan, R1
Hartshorn, K1
Andry, C1
Tablante, J1
Grillone, G1
McAvoy, D1
Suntra, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aerobic Physical Fitness and Health-related Quality of Life in Children With Sickle Cell Disease.[NCT05995743]72 participants (Actual)Observational2021-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydroxyurea and Injury, Ischemia-Reperfusion

ArticleYear
Exercise limitation, exercise testing and exercise recommendations in sickle cell anemia.
    Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4

    Topics: Adaptation, Physiological; Anemia, Sickle Cell; Arterial Occlusive Diseases; Bronchial Hyperreactivi

2011
Redox-dependent impairment of vascular function in sickle cell disease.
    Free radical biology & medicine, 2007, Dec-01, Volume: 43, Issue:11

    Topics: Anemia, Sickle Cell; Anti-Inflammatory Agents; Anticoagulants; Antioxidants; Biological Availability

2007

Other Studies

5 other studies available for hydroxyurea and Injury, Ischemia-Reperfusion

ArticleYear
Acute hydroxyurea treatment reduces tubular damage following bilateral ischemia-reperfusion injury in a mouse model of sickle cell disease.
    Biochemical and biophysical research communications, 2019, 07-12, Volume: 515, Issue:1

    Topics: Acute Kidney Injury; Anemia, Sickle Cell; Animals; Antisickling Agents; Biomarkers; Creatinine; Dise

2019
Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
    Molecular pharmacology, 2004, Volume: 66, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Disease Models, Animal; Hydroxyurea; Inflammation; Intercellul

2004
Effects of the arachidonate 5-lipoxygenase synthesis inhibitor A-64077 in intestinal ischemia-reperfusion injury.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Dogs; Hydroxyurea; Intestinal Mucosa; Intestines; Leukotriene

1994
Lung mast cells increase in number and degranulate during pulmonary artery occlusion/reperfusion injury in dogs.
    The American review of respiratory disease, 1993, Volume: 147, Issue:2

    Topics: Animals; Arterial Occlusive Diseases; Bronchoalveolar Lavage Fluid; Cell Count; Cell Degranulation;

1993
In vivo correlation of neutrophil receptor expression, ischemia-reperfusion injury, and selective 5-lipoxygenase inhibition in guinea pigs.
    Archives of otolaryngology--head & neck surgery, 1998, Volume: 124, Issue:12

    Topics: Animals; CD18 Antigens; Female; Guinea Pigs; Hydroxyurea; Lipoxygenase Inhibitors; Neutrophil Activa

1998