Page last updated: 2024-10-28

hydroxyurea and Infarction, Middle Cerebral Artery

hydroxyurea has been researched along with Infarction, Middle Cerebral Artery in 5 studies

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
" He was thought to have had an embolic stroke and was initially treated with warfarin."3.80Repeated episodes of ischemic stroke over a short period in a patient with essential thrombocythemia on anticoagulant therapy. ( Hirano, T; Isoda, K; Ito, K; Naganuma, M; Nishi, S, 2014)
"Default of therapy for polycythemia is associated with a profound risk of recurrent strokes requiring patient education and support to prevent the devastating consequence of this modifiable but rare cause of stroke."1.51Recurrent Stroke in a Ghanaian Patient With Polycythemia. ( Berchie, PO; Opare-Sem, OK; Ovbiagele, B; Sarfo, FS, 2019)
"Adult male Sprague-Dawley rats underwent middle cerebral artery occlusion (MCAO), then received treatment with zileuton or vehicle after the onset of ischemia."1.435-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway. ( Chen, CM; Liang, RS; Shi, SS; Tu, XK; Wang, CH; Yang, WZ; Zhang, HB, 2016)
"Oral treatment of zileuton at 10 or 50 mg/kg significantly reduced cerebral water content and infarct volume."1.355-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9. ( Chen, CM; Shi, SS; Tu, XK; Wang, CH; Yang, WZ, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berchie, PO1
Sarfo, FS1
Opare-Sem, OK1
Ovbiagele, B1
Shi, SS3
Yang, WZ3
Tu, XK3
Wang, CH3
Chen, CM3
Chen, Y1
Zhang, HB1
Liang, RS1
Naganuma, M1
Isoda, K1
Nishi, S1
Ito, K1
Hirano, T1

Other Studies

5 other studies available for hydroxyurea and Infarction, Middle Cerebral Artery

ArticleYear
Recurrent Stroke in a Ghanaian Patient With Polycythemia.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:3

    Topics: Aphasia, Broca; Aspirin; Clopidogrel; Ghana; Humans; Hydroxyurea; Infarction, Middle Cerebral Artery

2019
5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia.
    Inflammation, 2013, Volume: 36, Issue:6

    Topics: Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Brain; Brain Injuries; Caspase 1; Caspase 3; Hydrox

2013
5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway.
    Neurochemical research, 2016, Volume: 41, Issue:10

    Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Brain Ischemia; Hydroxyurea; Infarction, Middle Cerebra

2016
5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9.
    Neurological research, 2009, Volume: 31, Issue:8

    Topics: Animals; Arachidonate 5-Lipoxygenase; Body Water; Brain; Brain Edema; Brain Ischemia; Dose-Response

2009
Repeated episodes of ischemic stroke over a short period in a patient with essential thrombocythemia on anticoagulant therapy.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:1

    Topics: Aged; Anticoagulants; Aphasia; Brain Ischemia; Cerebral Angiography; Cilostazol; Diffusion Magnetic

2014