Page last updated: 2024-10-28

hydroxyurea and Hypereosinophilic Syndrome

hydroxyurea has been researched along with Hypereosinophilic Syndrome in 47 studies

Hypereosinophilic Syndrome: A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.

Research Excerpts

ExcerptRelevanceReference
" The combination of IFN-alpha and hydroxyurea is very useful and allows dosage reduction of IFN-alpha and better control of hypereosinophilia than with either agent alone."2.43Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis. ( Butterfield, JH, 2005)
"We report four Arab patients with idiopathic hypereosinophilic syndrome (IHES)."2.41Idiopathic hypereosinophilic syndrome: a report of four cases in Arabs, and a review of the literature. ( Abdelaal, MA; Gangi, MT; George, BO; Kinsara, AJ, 2001)
"Cardiac tamponade is a rare but serious complication of IHES."1.35Cardiac tamponade: a rare complication of idiopathic hypereosinophilic syndrome. ( Ahmed, S; Duncan, B; Fernandez, AB; Firshein, S; Kluger, J, 2009)
"We report a rare case of eosinophilic leukemia transformation in a patient with polycythemia rubra vera on hydroxycarbamide (hydroxyurea) therapy only."1.33Eosinophilic leukemic transformation in polycythemia rubra vera (PRV). ( Chim, CS; Ma, SK, 2005)
"Idiopathic hypereosinophilic syndrome is a rare condition characterized by extremely high peripheral blood eosinophil counts."1.33Factor V Leiden mutation and deep venous thrombosis in a patient with hypereosinophilic syndrome. ( Aslan, V; Entok, E, 2006)
"The hypereosinophilic syndrome is a multi-organ disease characterized by large counts of eosinophils in peripheral blood observed during at least six months without any evidence for other known causes of eosinophilia."1.33[The hypereosinophilic syndrome: case report]. ( Grzybowski, G; Mikołajczyk, K; Samborski, W; Walkowiak, B; Zaba, R, 2006)
"Giant cell arteritis is a T-cell dependent auto-immune vasculitis that involves a T-helper l (Th1) cell response."1.31[Horton's disease and hypereosinophilic syndrome: a non-fortuitous association]. ( Gissot, V; Jauberteau, MO; Liozon, E; Loustaud, V; Soria, P; Vidal, E, 2000)
"Hypereosinophilic syndrome was diagnosed."1.31Successful treatment of hypereosinophilic syndrome in a dog. ( Perkins, M; Watson, A, 2001)
" The dosage schedule was governed by the clinical and echocardiographic findings."1.30[Löffler's parietal fibroplastic endocarditis. Echocardiographic course over 5 years]. ( Braun, B; Günther, E; Hust, MH; Metzler, B; Perier, P, 1997)
"One of our patients developed the adult respiratory distress syndrome thought to be a complication of the HES."1.29Pulmonary involvement in the hypereosinophilic syndrome. ( Kollef, MH; Meyer, JI; Winn, RE, 1994)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (21.28)18.2507
2000's24 (51.06)29.6817
2010's12 (25.53)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Iurlo, A1
Cattaneo, D1
Gianelli, U1
Groh, M1
Lefèvre, G1
Ackermann, F1
Étienne, N1
Kahn, JE2
Williams, AK1
Dou, C1
Chen, LYC1
Andersen, C1
Yadav, H1
Iyer, VN1
Rider, TG1
George, SMC1
Batool, A1
Tidbury, HL1
Grace, RJ1
Newman, JA1
Ali, Z1
Felton, JR1
Kim, JA1
Kim, N1
Choi, HS1
Choung, HK1
Khwarg, SI1
Gotlib, J1
Roufosse, F3
Takeuchi, Y1
Matsuura, S1
Fujino, Y1
Nakajima, M1
Takahashi, M1
Nakashima, K1
Sakai, Y1
Uetsuka, K1
Ohno, K1
Nakayama, H1
Tsujimoto, H1
Cocker, MS1
Abdel-Aty, H1
Alakija, P1
Strohm, O1
Friedrich, MG1
Butterfield, JH5
Fernandez, AB1
Ahmed, S1
Duncan, B1
Firshein, S1
Kluger, J1
Ogbogu, PU1
Bochner, BS1
Gleich, GJ1
Huss-Marp, J1
Leiferman, KM1
Nutman, TB1
Pfab, F1
Ring, J1
Rothenberg, ME1
Sajous, MH1
Sheikh, J1
Simon, D1
Simon, HU1
Stein, ML1
Wardlaw, A1
Weller, PF1
Klion, AD1
Srinivasan, A1
Lavanya, R1
Sankar, J1
Prochorec-Sobieszek, M1
Nasiłowska-Adamska, B1
Borg, K1
Kopeć, I1
Kos-Zakrzewska, K1
Juszczyński, P1
Warzocha, K1
Weiler, CR1
Kanthila, J1
Bhaskaranand, N1
Cogan, E1
Ault, P1
Cortes, J1
Koller, C1
Kaled, ES1
Kantarjian, H1
George, BO1
Abdelaal, MA1
Gangi, MT1
Kinsara, AJ1
Chim, CS1
Ma, SK1
Borbényi, Z1
Vogler, S1
Burkhard, R1
Florian, S1
Esterbauer, H1
Binder, T1
Müllauer, L1
Haas, OA1
Sperr, WR1
Sillaber, C1
Valent, P1
van Ruth, S1
Lokhorst, HM1
Bruijnzeel-Koomen, CA1
Aslan, V1
Entok, E1
Mikołajczyk, K1
Zaba, R1
Walkowiak, B1
Grzybowski, G1
Samborski, W1
Dahabreh, IJ2
Giannouli, S2
Zoi, C2
Zoi, K2
Voulgarelis, M2
Moutsopoulos, HM1
Sato, Y1
Fukunaga, T1
Hayashi, T1
Asada, Y1
Loukopoulos, D1
Hendrick, A1
Quiquandon, I1
Claisse, JF1
Capiod, JC1
Delobel, J1
Prin, L1
Lombardi, C1
Rusconi, C1
Faggiano, P1
Lanzani, G1
Campana, C1
Arbustini, E1
Winn, RE1
Kollef, MH1
Meyer, JI1
Esteve, J1
Cervantes, F1
Bosch, F1
Cobo, F1
Montserrat, E1
Rozman, C1
Metzler, B1
Günther, E1
Perier, P1
Braun, B1
Hust, MH1
Demiroglu, H1
Dündar, S1
Fruhwald, FM1
Aglas, F1
Schumacher, M1
Zweiker, R1
Eber, B1
Klein, W1
Bletry, O1
Díaz, F1
Collazos, J1
Means-Markwell, M1
Burgess, T1
deKeratry, D1
O'Neil, K1
Mascola, J1
Fleisher, T1
Lucey, D1
Liozon, E1
Soria, P1
Gissot, V1
Loustaud, V1
Jauberteau, MO1
Vidal, E1
Rimbrot, S1
Bennett, M1
Komorovski, M1
Levy, Y1
Schaller, JL1
Burkland, GA1
Perkins, M1
Watson, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome[NCT02101138]Phase 215 participants (Actual)Interventional2014-03-14Active, not recruiting
Assessment of Glucocorticoid Responsiveness and Mechanisms of Resistance in Hypereosinophilic Syndromes[NCT01524536]Phase 426 participants (Actual)Interventional2012-02-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Baseline Absolute Eosinophil Count

Mean baseline absolute eosinophil count in participants prior to initiation of glucocorticoids (NCT01524536)
Timeframe: Baseline (Day 1)

Intervention10^3 cells per microliter (Geometric Mean)
Steroid Challenge - Glucocorticoid Responsiveness2.81
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness3.85
Steroid Challenge - Glucocorticoid Unresponsiveness5.90

Mean Baseline IgE Level

Mean baseline immunoglobulin E (IgE) level in participants prior to initiation of glucocorticoid (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionIU/mL (Geometric Mean)
Steroid Challenge - Glucocorticoid Responsiveness285.2
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness1171.5
Steroid Challenge - Glucocorticoid Unresponsiveness434.8

Mean Percent Change in Eosinophil Count After Glucocorticoid Challenge

"Response to glucocorticoid challenge as assessed by the percentage of the eosinophil count 24 hours post-glucocorticoid challenge relative to the Baseline AEC for each participant.~Measure Description (%): Percent of baseline AEC is defined as the Absolute Eosinophil Count at 24 hours divided by the Absolute Eosinophil Count at Baseline *100." (NCT01524536)
Timeframe: 24 hours

Interventionpercentage of eosinophil count (Mean)
Steroid Challenge - Responders-69.6
Steroid Challenge - Non-responders-13.6

Participants With Glucocorticoid Responsiveness - Cardiac Involvement

Cardiac involvement in participants with hypereosinophilic syndromes (HES) (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness1
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness0
Steroid Challenge - Glucocorticoid Unresponsiveness4

Participants With Glucocorticoid Responsiveness - IHES Variant

Participants with idiopathic hypereosinophilic syndromes (IHES) that achieved glucocorticoid responsiveness, suboptimal responsiveness, or without response. (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness6
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness2
Steroid Challenge - Glucocorticoid Unresponsiveness2

Participants With Glucocorticoid Responsiveness - LHES Variant

Participants with lymphoid hypereosinophilic syndromes (LHES) that achieved glucocorticoid responsiveness, suboptimal responsiveness, or without response. (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness2
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness1
Steroid Challenge - Glucocorticoid Unresponsiveness2

Participants With Glucocorticoid Responsiveness - MHES Variant

Participants with myeloid hypereosinophilic syndromes (MHES) that achieved glucocorticoid responsiveness, suboptimal responsiveness, or without response. (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness0
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness0
Steroid Challenge - Glucocorticoid Unresponsiveness1

Participants With Glucocorticoid Responsiveness - Overlap HES Subtypes

Participants with overlap hypereosinophilic syndromes that achieved glucocorticoid responsiveness, suboptimal responsiveness, or without response. (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness3
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness2
Steroid Challenge - Glucocorticoid Unresponsiveness1

Participants With Glucocorticoid Responsiveness - Pulmonary Involvement

Pulmonary involvement in participants with hypereosinophilic syndromes (HES) (NCT01524536)
Timeframe: Baseline (Day 1)

InterventionParticipants (Count of Participants)
Steroid Challenge - Glucocorticoid Responsiveness4
Steroid Challenge - Glucocorticoid Suboptimal Responsiveness3
Steroid Challenge - Glucocorticoid Unresponsiveness3

Reviews

12 reviews available for hydroxyurea and Hypereosinophilic Syndrome

ArticleYear
Hypereosinophilic syndromes in the precision medicine era: clinical, molecular aspects and therapeutic approaches (targeted therapies).
    Expert review of hematology, 2019, Volume: 12, Issue:12

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Im

2019
Treatment of lymphocyte-variant hypereosinophilic syndrome (L-HES): what to consider after confirming the elusive diagnosis.
    British journal of haematology, 2021, Volume: 195, Issue:5

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal; Cyclosporine; Humans; Hydroxyurea; Hyp

2021
World Health Organization-defined eosinophilic disorders: 2014 update on diagnosis, risk stratification, and management.
    American journal of hematology, 2014, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Bone Marrow Examination; Clone Cells; Disease Manage

2014
Management of Hypereosinophilic Syndromes.
    Immunology and allergy clinics of North America, 2015, Volume: 35, Issue:3

    Topics: Adrenal Cortex Hormones; Eosinophils; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesy

2015
Treatment of hypereosinophilic syndromes--the first 100 years.
    Seminars in hematology, 2012, Volume: 49, Issue:2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Antiviral Agents

2012
Idiopathic hypereosinophilic syndrome in children: 3 cases with review of literature.
    Indian journal of pediatrics, 2013, Volume: 80, Issue:2

    Topics: Child, Preschool; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Infant; Male; Retrospecti

2013
Clinical management of the hypereosinophilic syndromes.
    Expert review of hematology, 2012, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Antibodies; Benzamides; Enzyme Inhibitors; Humans; Hydroxyurea; Hypereosino

2012
Idiopathic hypereosinophilic syndrome: a report of four cases in Arabs, and a review of the literature.
    African journal of medicine and medical sciences, 2001, Volume: 30, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Arabs; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Int

2001
[Disorders with eosinophilia, treatment of hypereosinophilic syndrome].
    Orvosi hetilap, 2005, May-01, Volume: 146, Issue:18 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Decision Trees; Eosinophilia; Glucocorti

2005
Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis.
    Acta haematologica, 2005, Volume: 114, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Movement; Cell Prolifera

2005
Treatment of hypereosinophilic syndromes with prednisone, hydroxyurea, and interferon.
    Immunology and allergy clinics of North America, 2007, Volume: 27, Issue:3

    Topics: Apoptosis; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Interferon-alpha; Interferon-gamma; Pred

2007
[The eosinophil: doctor Jekyll or mister Hyde?].
    Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:4 Suppl

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Eosinophils; Humans; Hydroxyurea; Hypereosinophilic

1998

Trials

1 trial available for hydroxyurea and Hypereosinophilic Syndrome

ArticleYear
Management of hypereosinophilic syndrome: a prospective study in the era of molecular genetics.
    Medicine, 2007, Volume: 86, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyto

2007

Other Studies

34 other studies available for hydroxyurea and Hypereosinophilic Syndrome

ArticleYear
[Hypereosinophilic syndromes].
    La Revue du praticien, 2019, Volume: 69, Issue:7

    Topics: Eosinophils; Glucocorticoids; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesylate

2019
38-Year-Old Man With Asthma and Eosinophilia.
    Mayo Clinic proceedings, 2017, Volume: 92, Issue:8

    Topics: Adult; Anti-Asthmatic Agents; Antineoplastic Agents; Asthma; Diagnosis, Differential; Disease Progre

2017
Image Gallery: A case of chronic eosinophilic leukaemia.
    The British journal of dermatology, 2017, Volume: 177, Issue:4

    Topics: Aged; Antineoplastic Agents; Exanthema; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Leukemia; M

2017
Eyelid Swelling and Subconjunctival Infiltration as Ophthalmic Manifestations in a Child with Idiopathic Hypereosinophilic Syndrome.
    Korean journal of ophthalmology : KJO, 2018, Volume: 32, Issue:6

    Topics: Child; Conjunctival Diseases; Drug Therapy, Combination; Edema; Enzyme Inhibitors; Eosinophils; Eyel

2018
Hypereosinophilic syndrome in two cats.
    The Journal of veterinary medical science, 2008, Volume: 70, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Blood Cell Count; Cat Diseases; Cats; Fatal Outcome; Female; Hema

2008
Images in cardiology. Cardiac magnetic resonance imaging in Löffler's endocarditis.
    The Canadian journal of cardiology, 2008, Volume: 24, Issue:11

    Topics: Biopsy, Needle; Bone Marrow; Chest Pain; Diagnosis, Differential; Drug Therapy, Combination; Endomyo

2008
Success of short-term, higher-dose imatinib mesylate to induce clinical response in FIP1L1-PDGFRalpha-negative hypereosinophilic syndrome.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Benzamides; Dose-Response Relationship, Drug

2009
Cardiac tamponade: a rare complication of idiopathic hypereosinophilic syndrome.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2009, Volume: 10, Issue:2

    Topics: Aged; Biopsy; Cardiac Tamponade; Echocardiography; Female; Humans; Hydroxyurea; Hypereosinophilic Sy

2009
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibod

2009
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibod

2009
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibod

2009
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibod

2009
Steroid-unresponsive hypereosinophilic syndrome.
    Annals of tropical paediatrics, 2011, Volume: 31, Issue:3

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Benzamides; Child; Drug Therapy, Combination; Human

2011
Chronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) with PCM1-JAK2 fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target?
    Leukemia & lymphoma, 2012, Volume: 53, Issue:9

    Topics: Antineoplastic Agents; Cell Proliferation; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; C

2012
Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate.
    Leukemia research, 2002, Volume: 26, Issue:9

    Topics: Alkylating Agents; Antimetabolites; Benzamides; Bone and Bones; Busulfan; Cladribine; Combined Modal

2002
Eosinophilic leukemic transformation in polycythemia rubra vera (PRV).
    Leukemia & lymphoma, 2005, Volume: 46, Issue:3

    Topics: Aged; Chromosome Aberrations; Cytogenetic Analysis; Humans; Hydroxyurea; Hypereosinophilic Syndrome;

2005
[A 69-year-old man with deep fatigue, weight loss and eosinophilia].
    Praxis, 2005, Nov-02, Volume: 94, Issue:44

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Diagnosis, Differential; Fatigue; Follow-Up St

2005
Systemic mastocytosis (SM) associated with chronic eosinophilic leukemia (SM-CEL): detection of FIP1L1/PDGFRalpha, classification by WHO criteria, and response to therapy with imatinib.
    Leukemia research, 2006, Volume: 30, Issue:9

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benz

2006
[Two patients with hypereosinophilic syndrome].
    Nederlands tijdschrift voor geneeskunde, 2006, May-27, Volume: 150, Issue:21

    Topics: Adult; Benzamides; Diagnosis, Differential; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Hypereos

2006
Factor V Leiden mutation and deep venous thrombosis in a patient with hypereosinophilic syndrome.
    Saudi medical journal, 2006, Volume: 27, Issue:9

    Topics: Adult; Anticoagulants; Coumarins; Enzyme Inhibitors; Factor V; Heparin, Low-Molecular-Weight; Humans

2006
[The hypereosinophilic syndrome: case report].
    Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2

    Topics: Adult; Benzamides; Bone Marrow; Diagnosis, Differential; Eosinophils; Humans; Hydroxyurea; Hypereosi

2006
Hypereosinophilic syndrome associated with occlusive coronary thrombosis and right ventricular thrombus.
    Pathology international, 2008, Volume: 58, Issue:2

    Topics: Adult; Coronary Angiography; Coronary Thrombosis; Coronary Vessels; Eosinophils; Fatal Outcome; Gluc

2008
Hypereosinophilic syndrome: another face of janus?
    Leukemia research, 2008, Volume: 32, Issue:9

    Topics: Aged; Chronic Disease; Female; Flow Cytometry; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Janu

2008
Psychosis during interferon in eosinophilic leukaemia.
    Clinical and laboratory haematology, 1994, Volume: 16, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Combined Modali

1994
alpha-Interferon and hypereosinophilic syndrome with trisomy 8: karyotypic remission.
    Blood, 1995, Apr-15, Volume: 85, Issue:8

    Topics: Chromosomes, Human, Pair 8; Combined Modality Therapy; Female; Humans; Hydroxyurea; Hypereosinophili

1995
Successful reduction of endomyocardial fibrosis in a patient with idiopathic hypereosinophilic syndrome. A case report.
    Angiology, 1995, Volume: 46, Issue:4

    Topics: Dipyridamole; Drug Therapy, Combination; Echocardiography, Doppler; Endomyocardial Fibrosis; Female;

1995
Pulmonary involvement in the hypereosinophilic syndrome.
    Chest, 1994, Volume: 105, Issue:3

    Topics: Adult; Critical Care; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Male; Middle Aged; Pr

1994
[Alpha interferon treatment in idiopathic hypereosinophilic syndrome resistant to conventional therapy].
    Medicina clinica, 1996, Mar-02, Volume: 106, Issue:8

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Drug Resistance, Multiple; Glucocorticoids;

1996
[Löffler's parietal fibroplastic endocarditis. Echocardiographic course over 5 years].
    Deutsche medizinische Wochenschrift (1946), 1997, Feb-14, Volume: 122, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Drug Therapy, Combination; Echocardiography, Transesophageal; Elect

1997
Combination of interferon-alpha and hydroxyurea in the treatment of idiopathic hypereosinophilic syndrome.
    British journal of haematology, 1997, Volume: 97, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Int

1997
Images in cardiovascular medicine. Löffler's endocarditis.
    Circulation, 1998, Mar-17, Volume: 97, Issue:10

    Topics: Anti-Inflammatory Agents; Echocardiography; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Male; M

1998
Reversible cerebellar involvement in the idiopathic hypereosinophilic syndrome.
    Postgraduate medical journal, 1999, Volume: 75, Issue:886

    Topics: Aged; Cerebellar Diseases; Female; Glucocorticoids; Humans; Hydroxyurea; Hypereosinophilic Syndrome;

1999
Eosinophilia with aberrant T cells and elevated serum levels of interleukin-2 and interleukin-15.
    The New England journal of medicine, 2000, May-25, Volume: 342, Issue:21

    Topics: Adult; Antineoplastic Agents; Dyspnea; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Interleukin-

2000
[Horton's disease and hypereosinophilic syndrome: a non-fortuitous association].
    Annales de medecine interne, 2000, Volume: 151, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Female; Giant Cell Arteritis; Glucocorticoids; Humans; Hydroxyurea;

2000
[Eosinophilic ascites as a presenting symptom of the hypereosinophilic syndrome].
    Harefuah, 2001, Volume: 140, Issue:6

    Topics: Adult; Ascitic Fluid; Asthma; Diagnosis, Differential; Eosinophilia; Humans; Hydroxyurea; Hypereosin

2001
Case report: rapid and complete control of idiopathic hypereosinophilia with imatinib mesylate.
    MedGenMed : Medscape general medicine, 2001, Sep-07, Volume: 3, Issue:5

    Topics: Adult; Benzamides; Drug Therapy, Combination; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imati

2001
Successful treatment of hypereosinophilic syndrome in a dog.
    Australian veterinary journal, 2001, Volume: 79, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Dog Diseases; Dogs; Enzyme Inhibitors; Eosinophilia; Female; Hydr

2001