hydroxyurea has been researched along with Hepatocellular Carcinoma in 28 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of 40 ppm diethylnitrosamine (DENA) in the drinking water for 10 weeks to male Fischer rats led to hepatocellular carcinoma in 100 percent with metastasis to the lung in 40 percent, of the animals living for the full experimental period of 20 weeks." | 3.65 | Modification of diethylnitrosamine liver carcinogenesis with phenobarbital but not with immunosuppression. ( Madison, RM; Viguera, C; Ward, JM; Weisburger, EK; Weisburger, JH, 1975) |
| "N1-S1/FdUrd Novikoff hepatoma cells, which lack thymidine kinase activity, are resistant to 5-fluorouracil (FUra) as well as 5-fluorodeoxyuridine (FdUrd), suggesting that the pathway, FUra leads to FdUrd leads to FdUMP, is utilized for the conversion of FUra to FdUMP." | 1.26 | Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells. ( Crumley, J; Wilkinson, DS, 1977) |
| "Populations of Novikoff rat hepatoma cells (subline N1S1-67) were monitored for the rates of transport of various substrates and for their incorporation into acid-insoluble material as a function of the age of cultures of randomly growing cells in suspension as well as during traverse of the cells through the cell cycle." | 1.25 | Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells. ( Erbe, J; Plagemenn, PG; Richey, DP; Zylka, JM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (75.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zegura, B | 1 |
| Sedmak, B | 1 |
| Filipic, M | 1 |
| BLOEDOW, CE | 1 |
| Severin, I | 1 |
| Padieu, M | 1 |
| Lhuguenot, JC | 1 |
| Chagnon, MC | 1 |
| Huang, XW | 1 |
| Tang, ZY | 1 |
| Lawrence, TS | 1 |
| Zhang, M | 1 |
| Arbiser, JL | 1 |
| Martinez, C | 1 |
| Arbiser, ZK | 1 |
| Adler, GK | 1 |
| Rosen, LB | 1 |
| Majzoub, JA | 1 |
| Takimoto, M | 1 |
| Sermsuvitayawong, K | 1 |
| Matsubara, K | 1 |
| Melegari, M | 1 |
| Scaglioni, PP | 1 |
| Wands, JR | 1 |
| Grant, GM | 1 |
| Jackman, SM | 1 |
| Kolanko, CJ | 1 |
| Stenger, DA | 1 |
| Segerling, M | 2 |
| Ohanian, SH | 2 |
| Borsos, T | 2 |
| Barranco, SC | 1 |
| Haenelt, BR | 1 |
| Gee, EL | 1 |
| Plagemenn, PG | 1 |
| Richey, DP | 2 |
| Zylka, JM | 2 |
| Erbe, J | 3 |
| Weisburger, JH | 1 |
| Madison, RM | 1 |
| Ward, JM | 1 |
| Viguera, C | 1 |
| Weisburger, EK | 1 |
| Balhorn, R | 2 |
| Jackson, V | 1 |
| Granner, D | 2 |
| Chalkey, R | 1 |
| Wilkinson, DS | 1 |
| Crumley, J | 1 |
| Blocker, R | 1 |
| Roth, JS | 1 |
| Cameron, IL | 1 |
| Rogers, W | 1 |
| Plagemann, PG | 3 |
| Marz, R | 1 |
| Wohlhueter, RM | 1 |
| Miller-Faurès, A | 1 |
| Blave, A | 1 |
| Caudron, M | 1 |
| Sene, C | 1 |
| Miller, AO | 1 |
| Geddes, EW | 1 |
| Falkson, G | 1 |
| Elford, HL | 1 |
| Lea, MA | 1 |
| Sasovetz, D | 1 |
| Musella, A | 1 |
| Morris, HP | 1 |
| Schultz, A | 1 |
| Sasaki, M | 1 |
| Natelson, S | 1 |
| Lin, JK | 1 |
| Chiu, IS | 1 |
| Tanphaichitr, N | 1 |
| Chalkley, R | 1 |
| Thompson, EB | 1 |
| Granner, DK | 1 |
| Tomkins, GM | 1 |
28 other studies available for hydroxyurea and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Microcystin-LR induces oxidative DNA damage in human hepatoma cell line HepG2.
Topics: Bacterial Toxins; Carcinoma, Hepatocellular; Cyanobacteria; Cytarabine; Dimethyl Sulfoxide; DNA Dama | 2003 |
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MISCELLANEOUS TUMORS.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Carcinom | 1964 |
Toxic interaction between hydroxyurea and 1-beta-D-arabino-furanosylcytosine on the DNA of a human hepatoma cell line (HEPG2).
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytarabine; DNA Damage; DNA Repair; Drug S | 2003 |
5-fluorouracil and hydroxyurea enhance adenovirus-mediated transgene expression in colon and hepatocellular carcinoma cells.
Topics: Adenoviridae; Antimetabolites, Antineoplastic; Antineoplastic Agents; beta-Galactosidase; Carcinoma, | 2005 |
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Topics: Carcinoma, Hepatocellular; Cell Line; Colforsin; Dexamethasone; Gene Expression Regulation, Neoplast | 1994 |
Identification of cellular proteins that bind the central conserved region of p53.
Topics: Amino Acid Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Conserved Sequ | 1994 |
Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective.
Topics: 2-Aminopurine; Amino Acid Sequence; Antiviral Agents; Blotting, Northern; Carcinoma, Hepatocellular; | 1998 |
JP-8 jet fuel-induced DNA damage in H4IIE rat hepatoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Comet Assay; Cytarabine; DNA Damage; D | 2001 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carci | 1975 |
Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cyta | 1978 |
Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Choline; D | 1975 |
Modification of diethylnitrosamine liver carcinogenesis with phenobarbital but not with immunosuppression.
Topics: Animals; Antilymphocyte Serum; Carcinoma, Hepatocellular; Diethylnitrosamine; Hydroxyurea; Immunosup | 1975 |
Phosphorylation of the lysine-rich histones throughout the cell cycle.
Topics: Autoradiography; Carcinoma, Hepatocellular; Cells, Cultured; Demecolcine; DNA, Neoplasm; Electrophor | 1975 |
Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxyuridine; DNA Replication; Drug Re | 1977 |
The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Hydroxyu | 1977 |
Total intravenous hyperalimentation and hydroxyurea chemotherapy in hepatoma-bearing rats.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Drinking; Eating; Hydroxyurea; Intestine, Small; Li | 1977 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxy | 1978 |
Flow cytometric analysis of hepatoma tissue and HeLa cells grown on various types of microbeads using hydroxyurea, nocodazole and aphidicolin in succession.
Topics: Aphidicolin; Benzimidazoles; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cytological Techn | 1985 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotra | 1970 |
Effect of hydroxyurea on ribonucleotide reductase.
Topics: Animals; Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry; Chick Embryo; Cytosine Nucleotide | 1968 |
Effects of hydroxyurea and 6-mercaptopurine on growth and some aspects of carbohydrate metabolism in regenerating and neoplastic liver.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Glucokinase; Glucose; Hepatecto | 1970 |
Thymidine transport by Novikoff rat hepatoma cells synchronized by double hydroxyurea treatment.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chroma | 1974 |
Comparison of the ribonucleotide with the canavanine reductase system.
Topics: Amino Acid Oxidoreductases; Animals; Canavanine; Carcinoma, Hepatocellular; Cell Division; Cells, Cu | 1974 |
Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Cytidine; Deamination | 1974 |
Partial inhibition of hydroxyurea on liver tumors induced by N, N-dimethyl-4-aminoazobenzene.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Azo Compounds; Carcinoma, Hepatocellular; Dimethylamine | 1974 |
Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.
Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Enzyme Activation; Histone | 1974 |
Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antimetabolites; Carcinoma, Hepatocellular; Cell Line; Compleme | 1974 |
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Topics: Animals; Antibodies; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dact | 1970 |