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hydroxyurea and Hemoglobinuria

hydroxyurea has been researched along with Hemoglobinuria in 3 studies

Hemoglobinuria: The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.

Research Excerpts

ExcerptRelevanceReference
"Some, but not all, beta-thalassemia/hemoglobin E (beta-thal/HbE) patients respond to hydroxyurea treatment."9.11In vivo and in vitro studies of fetal hemoglobin induction by hydroxyurea in beta-thalassemia/hemoglobin E patients. ( Chuncharunee, S; Fucharoen, S; Kongnium, W; Rodgers, GP; Sanmund, D; Watanapokasin, Y; Winichagoon, P, 2005)
"Some, but not all, beta-thalassemia/hemoglobin E (beta-thal/HbE) patients respond to hydroxyurea treatment."5.11In vivo and in vitro studies of fetal hemoglobin induction by hydroxyurea in beta-thalassemia/hemoglobin E patients. ( Chuncharunee, S; Fucharoen, S; Kongnium, W; Rodgers, GP; Sanmund, D; Watanapokasin, Y; Winichagoon, P, 2005)
"Clinical severity of thalassemia intermedia increases with age, with more severe anemia and more frequent complications such as extramedullary hematopoiesis and iron overload mainly related to increased intestinal absorption."1.40[Current management of thalassemia intermedia]. ( Thuret, I, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thuret, I1
Watanapokasin, Y1
Chuncharunee, S1
Sanmund, D1
Kongnium, W1
Winichagoon, P2
Rodgers, GP2
Fucharoen, S2
Siritanaratkul, N1
Chowthaworn, J1
Siriboon, W1
Muangsup, W1
Chaicharoen, S1
Poolsup, N1
Chindavijak, B1
Pootrakul, P1
Piankijagum, A1
Schechter, AN1

Trials

2 trials available for hydroxyurea and Hemoglobinuria

ArticleYear
In vivo and in vitro studies of fetal hemoglobin induction by hydroxyurea in beta-thalassemia/hemoglobin E patients.
    Experimental hematology, 2005, Volume: 33, Issue:12

    Topics: Adult; beta-Thalassemia; Cells, Cultured; Drug Monitoring; Erythroid Cells; Female; Fetal Hemoglobin

2005
Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease.
    Blood, 1996, Feb-01, Volume: 87, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Combined Modality Therapy; Erythrocyte Count

1996

Other Studies

1 other study available for hydroxyurea and Hemoglobinuria

ArticleYear
[Current management of thalassemia intermedia].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2014, Volume: 21, Issue:4-5

    Topics: Allografts; alpha-Thalassemia; beta-Thalassemia; Blood Transfusion; Chelation Therapy; Combined Moda

2014