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hydroxyurea and Hematologic Diseases

hydroxyurea has been researched along with Hematologic Diseases in 18 studies

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
"Five patients treated with hydroxyurea for various haematological malignancies developed multiple painful oral ulcers."7.69Painful oral ulcers with hydroxyurea therapy. ( Ainoon, O; Cheong, SK; Hamidah, NH; Norhaya, MR, 1997)
"In an attempt to improve the primary treatment of malignant gliomas we used a concomitant 6-week course of chemoradiotherapy with 5 fluorouracil (5 FU) and hydroxyurea (HU) in 24 adults with anaplastic astrocytoma (AA) (7 cases) or glioblastomas (GLB) (17 cases)."5.07Pilot study of 6 weeks of chemoradiotherapy with 5 FU and hydroxyurea in malignant gliomas. ( Armand, JP; Cioloca, C; Constans, JP; Cvitkovic, FB; Haie-Meder, C; Maugis, N; Papadimitrakopoulou, V, 1993)
"Five patients treated with hydroxyurea for various haematological malignancies developed multiple painful oral ulcers."3.69Painful oral ulcers with hydroxyurea therapy. ( Ainoon, O; Cheong, SK; Hamidah, NH; Norhaya, MR, 1997)
"Hydroxyurea was temporarily discontinued for predefined toxicity."2.70A two-year pilot trial of hydroxyurea in very young children with sickle-cell anemia. ( Lane, PA; Rogers, ZR; Scott, JP; Wang, WC; Ware, RE; Wynn, LW, 2001)
"Patients with advanced colorectal cancer and no prior chemotherapy were randomized to six treatment regimens: A) fluorouracil (FU) alone; B) FU + hydroxyurea (HU); C) semustine (SE) + dacarbazine (DA); D) FU + HU alternating with SE + DA; E) SE + razoxane (RA); F) mitomycin (MI) + DA."2.65Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278). ( Engstrom, PF; Klaassen, DJ; MacIntyre, JM; Mittelman, A, 1984)
"Prepubertal patients with childhood cancer or hematological disorders were more likely to have significantly reduced spermatogonial quantity compared to healthy controls (48."1.91Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort. ( Feijen, EAM; Goossens, E; Jahnukainen, K; Kremer, LMC; Masliukaite, I; Meissner, A; Ntemou, E; Repping, S; Soufan, AT; van de Wetering, M; van Pelt, AMM, 2023)
"The pleural effusion was transudative, although there was no history of cardiac failure or hypoalbuminemia, and treatment with diuretics failed."1.62Transudative Pleural Effusion Associated with Extramedullary Hematopoiesis. ( Amaki, J; Aoki, T; Asano, K; Enokida, K; Hayama, N; Oguma, T; Okada, N; Takeuchi, T; Takihara, T; Tomomatsu, K, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's4 (22.22)18.2507
2000's5 (27.78)29.6817
2010's2 (11.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Masliukaite, I1
Ntemou, E1
Feijen, EAM1
van de Wetering, M1
Meissner, A1
Soufan, AT1
Repping, S1
Kremer, LMC1
Jahnukainen, K1
Goossens, E1
van Pelt, AMM1
Enokida, K1
Tomomatsu, K1
Okada, N1
Takeuchi, T1
Takihara, T1
Amaki, J1
Hayama, N1
Oguma, T1
Aoki, T1
Asano, K1
Russo, G1
De Franceschi, L1
Colombatti, R1
Rigano, P1
Perrotta, S1
Voi, V1
Palazzi, G1
Fidone, C1
Quota, A1
Graziadei, G1
Pietrangelo, A1
Pinto, V1
Ruffo, GB1
Sorrentino, F1
Venturelli, D1
Casale, M1
Ferrara, F1
Sainati, L1
Cappellini, MD1
Piga, A1
Maggio, A1
Forni, GL1
Tsai, M1
Kita, A1
Leach, J1
Rounsevell, R1
Huang, JN1
Moake, J1
Ware, RE2
Fletcher, DA1
Lam, WA1
Kühr, T1
Burgstaller, S1
Apfelbeck, U1
Linkesch, W1
Seewann, H1
Fridrik, M1
Michlmayr, G1
Krieger, O1
Lutz, D1
Lin, W1
Pont, J1
Köck, L1
Abbrederis, K1
Baldinger, C1
Buder, R1
Geissler, D1
Hausmaninger, H1
Lang, A1
Zabernigg, A1
Duba, C1
Hilbe, W1
Eisterer, W1
Fiegl, M1
Greil, R1
Gastl, G1
Thaler, J1
Louvet, C1
Carrat, F1
Mal, F1
Mabro, M1
Beerblock, K1
Vaillant, JC1
Cady, J1
André, T1
Gamelin, E1
de Gramont, A1
SAMUELS, ML1
HOWE, CD1
Hampton, T1
Engstrom, PF1
MacIntyre, JM1
Mittelman, A1
Klaassen, DJ1
Kaneko, S1
Motomura, S1
Ibayashi, H1
Cvitkovic, FB1
Haie-Meder, C1
Papadimitrakopoulou, V1
Armand, JP1
Cioloca, C1
Maugis, N1
Constans, JP1
Norhaya, MR1
Cheong, SK1
Ainoon, O1
Hamidah, NH1
Ballas, SK1
Navarra, P1
Preziosi, P1
Powars, DR1
Wang, WC1
Wynn, LW1
Rogers, ZR1
Scott, JP1
Lane, PA1
Froom, P1
Quitt, M1
Aghai, E1
Richards, GJ1
Chambers, RG1

Reviews

3 reviews available for hydroxyurea and Hematologic Diseases

ArticleYear
Current challenges in the management of patients with sickle cell disease - A report of the Italian experience.
    Orphanet journal of rare diseases, 2019, 05-30, Volume: 14, Issue:1

    Topics: Anemia, Sickle Cell; Disease Management; Hematologic Diseases; Hemoglobinopathies; Humans; Hydroxyur

2019
Complications of sickle cell anemia in adults: guidelines for effective management.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:1

    Topics: Adult; Analgesics, Opioid; Anemia, Sickle Cell; Brain Diseases; Chest Pain; Child; Child, Preschool;

1999
Hydroxyurea: new insights on an old drug.
    Critical reviews in oncology/hematology, 1999, Volume: 29, Issue:3

    Topics: Arthritis, Rheumatoid; Hematologic Diseases; Humans; Hydroxyurea; Neoplasms; Ribonucleotide Reductas

1999

Trials

4 trials available for hydroxyurea and Hematologic Diseases

ArticleYear
A randomized study comparing interferon (IFN alpha) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic-phase chronic myeloid leukemia (CML).
    Leukemia research, 2003, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gastrointestinal Di

2003
Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278).
    American journal of clinical oncology, 1984, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Ne

1984
Pilot study of 6 weeks of chemoradiotherapy with 5 FU and hydroxyurea in malignant gliomas.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined

1993
A two-year pilot trial of hydroxyurea in very young children with sickle-cell anemia.
    The Journal of pediatrics, 2001, Volume: 139, Issue:6

    Topics: Age Factors; Anemia, Sickle Cell; Antisickling Agents; Blood Cell Count; Child, Preschool; Feasibili

2001

Other Studies

11 other studies available for hydroxyurea and Hematologic Diseases

ArticleYear
Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort.
    Human reproduction (Oxford, England), 2023, 03-01, Volume: 38, Issue:3

    Topics: Adult; Child; Cryopreservation; Fertility Preservation; Hematologic Diseases; Humans; Hydroxyurea; M

2023
Transudative Pleural Effusion Associated with Extramedullary Hematopoiesis.
    Internal medicine (Tokyo, Japan), 2021, Feb-01, Volume: 60, Issue:3

    Topics: Aged; Hematologic Diseases; Hematopoiesis, Extramedullary; Humans; Hydroxyurea; Male; Pleural Effusi

2021
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:1

    Topics: Anemia, Sickle Cell; Eptifibatide; Hematologic Diseases; Hemolytic-Uremic Syndrome; Hemorheology; Hu

2012
Prognostic factor analysis in advanced gastric cancer patients treated with hydroxyurea, leucovorin, 5-fluorouracil, and cisplatin (HLFP regimen).
    Cancer investigation, 2003, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, T

2003
RENAL ABNORMALITIES INDUCED BY HYDROXYUREA (NSC-32065).
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Antineoplastic Agents; Blood; Hematologic Diseases; Hematuria; Hydroxyurea; Kidney Diseases; Kidney

1964
Strides made in red blood cell disorders, but substantial barriers to care remain.
    JAMA, 2008, Jan-30, Volume: 299, Issue:4

    Topics: Anemia, Sickle Cell; Antisickling Agents; Benzoates; Brain Diseases; Chelation Therapy; Deferasirox;

2008
Differentiation of human bone marrow-derived fibroblastoid colony forming cells (CFU-F) and their roles in haemopoiesis in vitro.
    British journal of haematology, 1982, Volume: 51, Issue:2

    Topics: Adipose Tissue; Cell Count; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Rela

1982
Painful oral ulcers with hydroxyurea therapy.
    Singapore medical journal, 1997, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Hematologi

1997
Hydroxyurea in very young children with sickle cell anemia is not a cure-all.
    The Journal of pediatrics, 2001, Volume: 139, Issue:6

    Topics: Age Factors; Anemia, Sickle Cell; Antisickling Agents; Child, Preschool; Hematologic Diseases; Human

2001
The mean leukocyte myeloperoxidase index in hematological patients.
    American journal of clinical pathology, 1989, Volume: 92, Issue:6

    Topics: Hematologic Diseases; Hospitalization; Humans; Hydroxyurea; Leukocytes; Lymphoma; Lymphoma, Non-Hodg

1989
Hydroxyurea: a radiosensitizer in the treatment of neoplasms of the head and neck.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1969, Volume: 105, Issue:3

    Topics: Adult; Age Factors; Aged; Female; Gastrointestinal Diseases; Head; Head and Neck Neoplasms; Hematolo

1969