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hydroxyurea and HIV

hydroxyurea has been researched along with HIV in 12 studies

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

ExcerptRelevanceReference
"The goal of this study was to optimize the hydroxyurea dosage in HIV-infected patients, and to minimize the toxicity and maximize the antiviral efficacy of the hydroxyurea-didanosine combination."9.11Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency. ( Asmuth, D; Bakare, N; Blick, G; Farthing, C; Foli, A; Frank, I; Greiger, P; Groff, A; Herman, D; Lisziewicz, J; Lori, F; Lova, L; Norris, D; Peterson, D; Pollard, RB; Rashbaum, B; Schrader, S; Shalit, P; Tennenberg, A; Whitman, L, 2005)
"A 1993 presentation described the role of hydroxyurea in inhibiting HIV replication in peripheral blood mononuclear cells and macrophages as well as a synergistic effect with ddI."9.08Hydroxyurea in HIV therapy. ( , 1998)
" and Europe supports the effect of the anticancer drug hydroxyurea against HIV-1, and its potential synergistic effect with ddl."7.69Hydroxyurea, a potential new anti-HIV agent. ( Torres, G, 1995)
"Hydroxyurea was not found to be beneficial when used in association with STIs in patients during PHI."6.72The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse). ( Bloch, MT; Carr, A; Cooper, DA; Finlayson, RJ; Grey, P; Irvine, K; Kaldor, JM; Kelleher, AD; Law, M; McFarlane, R; Petoumenos, K; Quan, D; Smith, DE; Zaunders, JJ, 2006)
"The goal of this study was to optimize the hydroxyurea dosage in HIV-infected patients, and to minimize the toxicity and maximize the antiviral efficacy of the hydroxyurea-didanosine combination."5.11Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency. ( Asmuth, D; Bakare, N; Blick, G; Farthing, C; Foli, A; Frank, I; Greiger, P; Groff, A; Herman, D; Lisziewicz, J; Lori, F; Lova, L; Norris, D; Peterson, D; Pollard, RB; Rashbaum, B; Schrader, S; Shalit, P; Tennenberg, A; Whitman, L, 2005)
"A 1993 presentation described the role of hydroxyurea in inhibiting HIV replication in peripheral blood mononuclear cells and macrophages as well as a synergistic effect with ddI."5.08Hydroxyurea in HIV therapy. ( , 1998)
"Hydroxyurea obstructs HIV from reproducing, is effective when combined with nucleoside analogue reverse transcriptase inhibitors, and it is difficult for HIV to develop a resistance to it."3.70Hydroxyurea - new observations. ( , 1998)
" and Europe supports the effect of the anticancer drug hydroxyurea against HIV-1, and its potential synergistic effect with ddl."3.69Hydroxyurea, a potential new anti-HIV agent. ( Torres, G, 1995)
"Hydroxyurea was not found to be beneficial when used in association with STIs in patients during PHI."2.72The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse). ( Bloch, MT; Carr, A; Cooper, DA; Finlayson, RJ; Grey, P; Irvine, K; Kaldor, JM; Kelleher, AD; Law, M; McFarlane, R; Petoumenos, K; Quan, D; Smith, DE; Zaunders, JJ, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (66.67)18.2507
2000's4 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shirlaw, PJ1
Chikte, U1
MacPhail, L1
Schmidt-Westhausen, A1
Croser, D1
Reichart, P1
de Mendoza, C1
Paxinos, E1
Barreiro, P1
Camino, N1
Núñez, M1
Soriano, V1
Lori, F2
Pollard, RB1
Whitman, L1
Bakare, N1
Blick, G1
Shalit, P1
Foli, A1
Peterson, D1
Tennenberg, A1
Schrader, S1
Rashbaum, B1
Farthing, C1
Herman, D1
Norris, D1
Greiger, P1
Frank, I1
Groff, A1
Lova, L1
Asmuth, D1
Lisziewicz, J1
Bloch, MT1
Smith, DE1
Quan, D1
Kaldor, JM1
Zaunders, JJ1
Petoumenos, K1
Irvine, K1
Law, M1
Grey, P1
Finlayson, RJ1
McFarlane, R1
Kelleher, AD1
Carr, A1
Cooper, DA1
Ahluwalia, GS1
Gao, WY1
Mitsuya, H1
Johns, DG1
Cohen, J1
Szekeres, T1
Fritzer-Szekeres, M1
Elford, HL1
Mascolini, M1
Torres, G1

Reviews

3 reviews available for hydroxyurea and HIV

ArticleYear
Oral and dental care and treatment protocols for the management of HIV-infected patients.
    Oral diseases, 2002, Volume: 8 Suppl 2

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotic Prophylaxis; Antiretroviral Thera

2002
The enzyme ribonucleotide reductase: target for antitumor and anti-HIV therapy.
    Critical reviews in clinical laboratory sciences, 1997, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Antiviral Agents; Enzyme Inhibitors; HIV; Humans; Hydroxamic Acids; Hydroxyur

1997
Hydroxyurea and HIV: 5 years later--from antiviral to immune-modulating effects.
    AIDS (London, England), 1999, Aug-20, Volume: 13, Issue:12

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Nucleic Acid S

1999

Trials

3 trials available for hydroxyurea and HIV

ArticleYear
Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency.
    AIDS research and human retroviruses, 2005, Volume: 21, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Drug-Re

2005
The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse).
    Journal of acquired immune deficiency syndromes (1999), 2006, Volume: 42, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combinatio

2006
Hydroxyurea in HIV therapy.
    HIV hotline, 1998, Volume: 8, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; H

1998

Other Studies

6 other studies available for hydroxyurea and HIV

ArticleYear
Different viral rebound following discontinuation of antiretroviral therapy in cases of infection with viruses carrying L74V or thymidine-associated mutations.
    Journal of clinical microbiology, 2004, Volume: 42, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count;

2004
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reve

1996
HIV suppressed long after treatment.
    Science (New York, N.Y.), 1997, Sep-26, Volume: 277, Issue:5334

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Hepatitis A; HIV; HIV Infections; Humans; Hydroxy

1997
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations?
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug S

1995
Hydroxyurea - new observations.
    Project Inform perspective, 1998, Issue:24

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combinati

1998
Hydroxyurea, a potential new anti-HIV agent.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1

    Topics: Didanosine; DNA Replication; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Le

1995