hydroxyurea has been researched along with Genetic Predisposition in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Conversely, DO mice lacking adverse liver pathology following zileuton exposure experienced decreased hepatic concentrations of resistin and increased concentrations of insulin and leptin, providing potential clues into mechanisms of toxicity resistance." | 1.56 | Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice. ( Bell, N; Gatti, DM; Harrill, AH; James, LP; Larson, GJ; Lyn-Cook, LE; Mattes, WB; Mayeux, PR; You, D, 2020) |
| "Williams-Beuren syndrome (WBS, no." | 1.46 | DNA damage response defect in Williams-Beuren syndrome. ( Borg, C; Deconinck, E; Guenat, D; Merla, G; Rohrlich, PS, 2017) |
| "The chronic inflammatory state in sickle cell anemia (SCA) is associated with several factors such as the following: endothelial damage; increased production of reactive oxygen species; hemolysis; increased expression of adhesion molecules by leukocytes, erythrocytes, and platelets; and increased production of proinflammatory cytokines." | 1.40 | Chronic inflammatory state in sickle cell anemia patients is associated with HBB(*)S haplotype. ( Bandeira, IC; Barbosa, MC; Elias, DB; Freitas, MV; Gonçalves, RP; Querioz, JA; Rocha, LB, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, N | 1 |
| Qayum, S | 1 |
| Jameel, A | 1 |
| Ali, A | 1 |
| Siraj, S | 1 |
| Ali, J | 1 |
| Yousafzai, YM | 1 |
| You, D | 1 |
| Lyn-Cook, LE | 1 |
| Gatti, DM | 1 |
| Bell, N | 1 |
| Mayeux, PR | 1 |
| James, LP | 1 |
| Mattes, WB | 1 |
| Larson, GJ | 1 |
| Harrill, AH | 1 |
| Angona, A | 1 |
| Bellosillo, B | 1 |
| Alvarez-Larrán, A | 1 |
| Martínez-Avilés, L | 1 |
| Camacho, L | 1 |
| Pairet, S | 1 |
| Fernández-Rodriguez, MC | 1 |
| Ancochea, A | 1 |
| Besses, C | 1 |
| Green, NS | 1 |
| Barral, S | 1 |
| Bandeira, IC | 1 |
| Rocha, LB | 1 |
| Barbosa, MC | 1 |
| Elias, DB | 1 |
| Querioz, JA | 1 |
| Freitas, MV | 1 |
| Gonçalves, RP | 1 |
| Sivakumaran, Y | 1 |
| Freeman, A | 1 |
| Guenat, D | 1 |
| Merla, G | 1 |
| Deconinck, E | 1 |
| Borg, C | 1 |
| Rohrlich, PS | 1 |
| Hochhaus, A | 1 |
| Li, JY | 1 |
| Xu, W | 1 |
| Wu, W | 1 |
| Zhu, Y | 1 |
| Qiu, HR | 1 |
| Zhang, R | 1 |
| Zhang, SJ | 1 |
| Qian, SX | 1 |
| Meier, ER | 1 |
| Miller, JL | 1 |
| Davies, SL | 1 |
| North, PS | 1 |
| Dart, A | 1 |
| Lakin, ND | 1 |
| Hickson, ID | 1 |
| Steinberg, MH | 1 |
3 reviews available for hydroxyurea and Genetic Predisposition
| Article | Year |
|---|---|
Emerging science of hydroxyurea therapy for pediatric sickle cell disease.
Topics: Age Factors; Anemia, Sickle Cell; Animals; Antisickling Agents; Child; Child, Preschool; Fetal Hemog | 2014 |
Sickle cell disease in children.
Topics: Anemia, Sickle Cell; Blood Transfusion; Child; Child, Preschool; Genetic Predisposition to Disease; | 2012 |
Predicting clinical severity in sickle cell anaemia.
Topics: alpha-Thalassemia; Anemia, Sickle Cell; Antisickling Agents; Female; Fetal Hemoglobin; Genetic Predi | 2005 |
9 other studies available for hydroxyurea and Genetic Predisposition
| Article | Year |
|---|---|
Clinical and laboratory relevance of JAK2 V617F and BCR-ABL co-existence in Philadelphia positive CML patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Child; Female; Fusion Proteins, b | 2021 |
Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Chemical and Drug Induced Liver Injury; Collaborative Cross | 2020 |
Genetic predisposition to molecular response in patients with myeloproliferative neoplasms treated with hydroxycarbamide.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arginase; Female; Gene Frequency; Genetic Pre | 2013 |
Chronic inflammatory state in sickle cell anemia patients is associated with HBB(*)S haplotype.
Topics: Adult; Aged; Anemia, Sickle Cell; beta-Globins; Case-Control Studies; Chromosomes, Human; Chronic Di | 2014 |
Refractory Arterial Insufficiency Associated with Janus Kinase 2 Positive Essential Thrombocythaemia.
Topics: Amputation, Surgical; Angioplasty, Balloon; Anti-Bacterial Agents; Arterial Occlusive Diseases; Comp | 2017 |
DNA damage response defect in Williams-Beuren syndrome.
Topics: Case-Control Studies; Cell Cycle; Cell Line; Cell Proliferation; DNA Damage; DNA Repair; Dose-Respon | 2017 |
Prognostic factors in chronic myeloid leukemia (CML).
Topics: Chromosomes, Human, Pair 9; Female; Gene Deletion; Genetic Predisposition to Disease; Genetic Testin | 2008 |
The negative prognostic impact of derivative 9 deletions in patients who received hydroxyurea treatment for chronic myelogenous leukemia in the chronic phase.
Topics: Adolescent; Adult; Aged; Chromosomes, Human, Pair 9; Female; Gene Deletion; Genetic Predisposition t | 2008 |
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Bloom Synd | 2004 |