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hydroxyurea and Erythrocytosis

hydroxyurea has been researched along with Erythrocytosis in 31 studies

Research Excerpts

ExcerptRelevanceReference
"A patient given hydroxyurea for polycythemia suddenly developed severe interstitial pneumonia with fever and hypoxemia."7.70[Acute interstitial pneumopathy with fever caused by hydroxyurea]. ( Blanc, PL; Hammoud, H; Joasson, JM; Matussière, Y, 2000)
"Twenty-one polycythemia vera, 28 essential thrombocythemia, eight secondary erythrocytosis, and 30 controls were studied."5.37Differential expression of JAK2 and Src kinase genes in response to hydroxyurea treatment in polycythemia vera and essential thrombocythemia. ( Albizua, E; Ayala, R; Barrio, S; Besses, C; Espinet, B; Florensa, L; Gallardo, M; Jimenez, A; Martinez-Lopez, J; Puigdecanet, E; Rapado, I; Rueda, D; Sanchez-Espiridion, B, 2011)
"Hydroxyurea is a common cancer chemotherapy agent that inhibits ribonucleotide reductase, an enzyme essential to DNA synthesis."5.30Hydroxyurea-induced leg ulcers: is macroerythrocytosis a pathogenic factor? ( García-Aranda, JM; Moreno, JC; Vélez, A, 1999)
"Leg ulcers are a relatively frequent problem in patients with myeloproliferative disorders under treatment with hydroxyurea (HU)."4.80Leg ulcers in patients with myeloproliferative disorders: disease- or treatment-related? ( Bader, U; Banyai, M; Böni, R; Burg, G; Hafner, J, 2000)
"A patient given hydroxyurea for polycythemia suddenly developed severe interstitial pneumonia with fever and hypoxemia."3.70[Acute interstitial pneumopathy with fever caused by hydroxyurea]. ( Blanc, PL; Hammoud, H; Joasson, JM; Matussière, Y, 2000)
"In idiopathic myelofibrosis (IMF) PDGF is considered to be one of the growth factors responsible for the development of bone marrow fibrosis."2.71Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis. ( Birgens, H; Bjerrum, OW; Clausen, NT; Hansen, PB; Hasselbalch, HC; Jensen, BA; Ralfkiaer, E; Therkildsen, MH, 2003)
"Polycythemia vera (PV) and essential thrombocythemia (ET) are chronic disorders for which there are no medical cures."2.41Other secondary sequelae of treatments for myeloproliferative disorders. ( Gilbert, HS, 2002)
"Default of therapy for polycythemia is associated with a profound risk of recurrent strokes requiring patient education and support to prevent the devastating consequence of this modifiable but rare cause of stroke."1.51Recurrent Stroke in a Ghanaian Patient With Polycythemia. ( Berchie, PO; Opare-Sem, OK; Ovbiagele, B; Sarfo, FS, 2019)
"Twenty-one polycythemia vera, 28 essential thrombocythemia, eight secondary erythrocytosis, and 30 controls were studied."1.37Differential expression of JAK2 and Src kinase genes in response to hydroxyurea treatment in polycythemia vera and essential thrombocythemia. ( Albizua, E; Ayala, R; Barrio, S; Besses, C; Espinet, B; Florensa, L; Gallardo, M; Jimenez, A; Martinez-Lopez, J; Puigdecanet, E; Rapado, I; Rueda, D; Sanchez-Espiridion, B, 2011)
"The underlying cause was polycythemia rubra vera and osteomyolofibrosis."1.35[Budd-Chiari syndrome--from diagnosis to treatment--case reports]. ( Dybowska, D; Kozielewicz, D; Smukalska, E, 2008)
"Hydroxyurea seems to be an eddicient there alternative therapy for seconday polycythemia caused by incurable cyantic congenital heart disease."1.34[Chemotherapy against polycythemia due to a cyanotic congenital heart disease in adults. One case report]. ( Békir, S; Ben Romdhane, N; Boussaada, R; Mechmèche, R, 2007)
"Diagnosis of polycythemia vera during pregnancy is a very difficult task due to physiologic changes occurring during gestation."1.32[Polycythemia vera and pregnancy]. ( Beillat, T; Dreyfus, M; Macro, M, 2004)
"Hydroxyurea is a common cancer chemotherapy agent that inhibits ribonucleotide reductase, an enzyme essential to DNA synthesis."1.30Hydroxyurea-induced leg ulcers: is macroerythrocytosis a pathogenic factor? ( García-Aranda, JM; Moreno, JC; Vélez, A, 1999)
"Use of this test in cancer patients undergoing either chemotherapy or radiation therapy revealed evidence of early negative B12 balance that in some instances was induced by the treatment itself."1.29New assay for the rapid determination of plasma holotranscobalamin II levels: preliminary evaluation in cancer patients. ( Amin, J; Flener, V; Ramos, M; Tisman, G; Vanyo, L; Vu, T, 1993)
"The slower appearance of CFU-E in polycythemia was corrected by the injection of erythropoietin (Ep) 8 h prior to sacrifice, but an absolute increase in colony number only occurred when Ep was injected 24 h previously."1.27Studies on the kinetics of the erythroid colony-forming cell. ( Lipschitz, DA; Udupa, KB, 1986)
"Severe polycythemia was found in 3 dogs with PCV 68% to 70%."1.26Diagnosis of canine primary polycythemia and management with hydroxyurea. ( Peterson, ME; Randolph, JF, 1982)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.81)18.7374
1990's7 (22.58)18.2507
2000's11 (35.48)29.6817
2010's5 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berchie, PO1
Sarfo, FS1
Opare-Sem, OK1
Ovbiagele, B1
Ruella, M1
Salmoiraghi, S1
Risso, A1
Carobbio, A1
Buttiglieri, S1
Spatola, T1
Sivera, P1
Ricca, I1
Barbui, T1
Tarella, C1
Rambaldi, A1
Kozielewicz, D1
Smukalska, E1
Dybowska, D1
Albizua, E1
Gallardo, M1
Barrio, S1
Rapado, I1
Jimenez, A1
Ayala, R1
Rueda, D1
Sanchez-Espiridion, B1
Puigdecanet, E1
Espinet, B1
Florensa, L1
Besses, C1
Martinez-Lopez, J1
Kouroupi, E1
Cassinat, B1
Schlageter, MH1
Dosquet, C1
Kiladjian, JJ1
Chomienne, C1
Gemünden, C1
Gerber, B1
Hasselbalch, HC1
Bjerrum, OW1
Jensen, BA1
Clausen, NT1
Hansen, PB1
Birgens, H1
Therkildsen, MH1
Ralfkiaer, E1
Beillat, T1
Macro, M1
Dreyfus, M1
Rossi, D1
Cortini, F1
Deambrogi, C1
Barbieri, C1
Cerri, M1
Franceschetti, S1
Conconi, A1
Capello, D1
Gaidano, G1
Reiss, UM1
Bensimhon, P1
Zimmerman, SA1
Ware, RE1
Tomson, N1
Sterling, JC1
Boussaada, R1
Békir, S1
Ben Romdhane, N1
Mechmèche, R1
Tutaeva, V1
Misurin, AV1
Michiels, JJ1
Rozenberg, JM1
Sokolova, MA1
Ivanova, VL1
Kolosheinova, TI1
Manakova, TE1
Levina, AA1
Semenova, EA1
Khoroshko, ND1
Pavlovíc-Kentera, V1
Milenković, P1
Seidel, HJ1
Kreja, L1
Peterson, ME1
Randolph, JF1
Najean, Y2
Rain, JD1
Toubert, ME1
Vu, T1
Amin, J1
Ramos, M1
Flener, V1
Vanyo, L1
Tisman, G1
Dapling, RB1
Snowden, JA1
West, J1
Talbot, JF1
Nelson, ME1
Greaves, M1
van der Klooster, JM1
Sucec, PM1
Stiegelis, WF1
Hagenbeek, A1
Vélez, A1
García-Aranda, JM1
Moreno, JC1
Bader, U1
Banyai, M1
Böni, R1
Burg, G1
Hafner, J1
Blanc, PL1
Joasson, JM1
Hammoud, H1
Matussière, Y1
Gilbert, HS1
McCuskey, RS1
Meineke, HA1
Rencricca, NJ1
Morse, BS1
Monette, FC1
Howard, D1
Stohlman, F1
Legrand, M1
Poirier, O1
Senechal, A1
Arrago, JP1
Page, RL1
Stiff, ME1
McEntee, MC1
Walter, LG1
Hocking, WG1
Golde, DW1
Udupa, KB1
Lipschitz, DA1
Walterspiel, JN1
Buchanan, GR1
Schad, GA1
Carpentieri, U1

Reviews

4 reviews available for hydroxyurea and Erythrocytosis

ArticleYear
Fever caused by hydroxyurea: a report of three cases and review of the literature.
    The Netherlands journal of medicine, 1997, Volume: 51, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fever; Humans; Hydroxyurea; Male; Middle Age

1997
Leg ulcers in patients with myeloproliferative disorders: disease- or treatment-related?
    Dermatology (Basel, Switzerland), 2000, Volume: 200, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Female; Follow-Up Studies; Humans; Hydroxyurea; Leg

2000
Other secondary sequelae of treatments for myeloproliferative disorders.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 10

    Topics: Antineoplastic Agents; Fibrinolytic Agents; Humans; Hydroxyurea; Immunologic Factors; Interferon-alp

2002
Polycythemia: evaluation and management.
    Blood reviews, 1989, Volume: 3, Issue:1

    Topics: Adult; Aged; Bloodletting; Humans; Hydroxyurea; Middle Aged; Polycythemia; Polycythemia Vera

1989

Trials

2 trials available for hydroxyurea and Erythrocytosis

ArticleYear
Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis.
    American journal of hematology, 2003, Volume: 74, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Female;

2003
[Treatment of polycythemia with 32P with or without hydroxyurea maintenance therapy. Preliminary results in 237 elderly and high vascular risk subjects studied since 1980].
    Presse medicale (Paris, France : 1983), 1993, Dec-11, Volume: 22, Issue:39

    Topics: Age Factors; Aged; Carcinoma; Cardiovascular Diseases; Female; Humans; Hydroxyurea; Injections, Intr

1993

Other Studies

25 other studies available for hydroxyurea and Erythrocytosis

ArticleYear
Recurrent Stroke in a Ghanaian Patient With Polycythemia.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:3

    Topics: Aphasia, Broca; Aspirin; Clopidogrel; Ghana; Humans; Hydroxyurea; Infarction, Middle Cerebral Artery

2019
Telomere shortening in Ph-negative chronic myeloproliferative neoplasms: a biological marker of polycythemia vera and myelofibrosis, regardless of hydroxycarbamide therapy.
    Experimental hematology, 2013, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Clone Cells; Female

2013
[Budd-Chiari syndrome--from diagnosis to treatment--case reports].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24, Issue:141

    Topics: Adult; Anticoagulants; Budd-Chiari Syndrome; Female; Humans; Hydroxyurea; Polycythemia; Primary Myel

2008
Differential expression of JAK2 and Src kinase genes in response to hydroxyurea treatment in polycythemia vera and essential thrombocythemia.
    Annals of hematology, 2011, Volume: 90, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Gene Expression Profiling; Gene Expres

2011
Coexistence of a myeloproliferative disorder and secondary polycythemia in the same patient.
    American journal of hematology, 2012, Volume: 87, Issue:6

    Topics: Aged, 80 and over; Comorbidity; Drug Resistance; Erythropoiesis; Erythropoietin; Humans; Hydroxyurea

2012
[Polycythemia vera].
    Praxis, 2012, May-09, Volume: 101, Issue:10

    Topics: Aged; Algorithms; Alleles; Bone Marrow Examination; Diagnosis, Differential; Erythropoietin; Female;

2012
[Polycythemia vera and pregnancy].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2004, Volume: 33, Issue:6 Pt 1

    Topics: Adult; Antisickling Agents; Aspirin; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hum

2004
Usefulness of JAK2V617F mutation in distinguishing idiopathic erythrocytosis from polycythemia vera.
    Leukemia research, 2007, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Aspirin; Bone Marrow; Diagnosis, Differenti

2007
Hydroxyurea therapy for management of secondary erythrocytosis in cyanotic congenital heart disease.
    American journal of hematology, 2007, Volume: 82, Issue:8

    Topics: Adolescent; Adult; Female; Heart Defects, Congenital; Humans; Hydroxyurea; Male; Polycythemia

2007
Hydroxycarbamide: a treatment for lichen sclerosus?
    The British journal of dermatology, 2007, Volume: 157, Issue:3

    Topics: Aged; Antineoplastic Agents; Female; Humans; Hydroxyurea; Polycythemia; Treatment Outcome; Vulvar Li

2007
[Chemotherapy against polycythemia due to a cyanotic congenital heart disease in adults. One case report].
    La Tunisie medicale, 2007, Volume: 85, Issue:5

    Topics: Adult; Erythrocytes; Follow-Up Studies; Heart Defects, Congenital; Heart Septal Defects, Ventricular

2007
Application of PRV-1 mRNA expression level and JAK2V617F mutation for the differentiating between polycytemia vera and secondary erythrocytosis and assessment of treatment by interferon or hydroxyurea.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:6

    Topics: Diagnosis, Differential; GPI-Linked Proteins; Humans; Hydroxyurea; Interferon-alpha; Isoantigens; Ja

2007
Effect of erythropoietin on erythropoietin-responsive cell regeneration in polycythemic mice treated with cyclophosphamide.
    Acta haematologica, 1981, Volume: 66, Issue:1

    Topics: Animals; Cell Division; Cyclophosphamide; Erythropoiesis; Erythropoietin; Female; Hematopoietic Stem

1981
Studies on the resistance of the C57B1/6 mouse strain to the polycythemia-inducing strain of the Friend virus (FV-P).
    Blut, 1981, Volume: 42, Issue:3

    Topics: Animals; Bone Marrow Transplantation; Cell Division; Endotoxins; Female; Friend murine leukemia viru

1981
Diagnosis of canine primary polycythemia and management with hydroxyurea.
    Journal of the American Veterinary Medical Association, 1982, Feb-15, Volume: 180, Issue:4

    Topics: Animals; Dog Diseases; Dogs; Female; Hydroxyurea; Male; Polycythemia

1982
New assay for the rapid determination of plasma holotranscobalamin II levels: preliminary evaluation in cancer patients.
    American journal of hematology, 1993, Volume: 42, Issue:2

    Topics: Adsorption; Chromatography; Glass; Hematologic Tests; Homocysteine; Humans; Hydroxyurea; Microsphere

1993
The microvasculature in myeloproliferative disease. A study using retinal fluorescein angiography.
    Clinical and laboratory haematology, 1996, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Allergens; Antineoplastic Agents; Arterial Occlusive Diseases; Aspir

1996
Hydroxyurea-induced leg ulcers: is macroerythrocytosis a pathogenic factor?
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1999, Volume: 12, Issue:3

    Topics: Animals; Dogs; Female; Humans; Hydroxyurea; Leg Ulcer; Middle Aged; Nucleic Acid Synthesis Inhibitor

1999
[Acute interstitial pneumopathy with fever caused by hydroxyurea].
    Presse medicale (Paris, France : 1983), 2000, Feb-12, Volume: 29, Issue:5

    Topics: Aged; Aged, 80 and over; Female; Fever; Follow-Up Studies; Humans; Hydroxyurea; Lung Diseases, Inter

2000
Studies of the hemopoietic microenvironment. V. Erythropoietin-induced release of vasoactive substance(s) from erythropoietin-responsive stem cells (39902).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 156, Issue:1

    Topics: Animals; Busulfan; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hematopoietic Stem Cells; Hyd

1977
Hydroxyurea-induced erythroid differentiation.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:4

    Topics: Animals; Antibodies; Cell Count; Erythropoietin; Female; Hematocrit; Hematopoietic Stem Cells; Hydro

1975
Clinical significance of serum pro-collagen III in chronic myeloproliferative disorders.
    European journal of haematology, 1990, Volume: 45, Issue:5

    Topics: Aged; Bloodletting; Humans; Hydroxyurea; Myeloproliferative Disorders; Polycythemia; Polycythemia Ve

1990
Transient glomerulonephropathy associated with primary erythrocytosis in a dog.
    Journal of the American Veterinary Medical Association, 1990, Feb-15, Volume: 196, Issue:4

    Topics: Animals; Bloodletting; Combined Modality Therapy; Dog Diseases; Dogs; Doxorubicin; Female; Hydroxyur

1990
Studies on the kinetics of the erythroid colony-forming cell.
    Experimental hematology, 1986, Volume: 14, Issue:5

    Topics: Anemia; Animals; Blood Sedimentation; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay

1986
Erythropoietin-induced congenital erythrocytosis: treatment with myelosuppressive agents and hookworm infestation.
    The Journal of pediatrics, 1985, Volume: 107, Issue:4

    Topics: Bloodletting; Erythropoietin; Female; Hookworm Infections; Humans; Hydroxyurea; Infant; Methotrexate

1985