hydroxyurea has been researched along with Endotoxemia in 1 studies
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigate the effects of treatment with 5-LOX inhibitor zileuton in rats and targeted disruption of the 5-LOX gene in mice (5-LOX(-/-)) on multiple organ injury/dysfunction caused by severe endotoxemia." | 7.72 | Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. ( Collin, M; Collino, M; Cuzzocrea, S; Di Paola, R; Hadley, J; Patel, NS; Rossi, A; Sautebin, L; Thiemermann, C, 2004) |
| " Here, we investigate the effects of treatment with 5-LOX inhibitor zileuton in rats and targeted disruption of the 5-LOX gene in mice (5-LOX(-/-)) on multiple organ injury/dysfunction caused by severe endotoxemia." | 3.72 | Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. ( Collin, M; Collino, M; Cuzzocrea, S; Di Paola, R; Hadley, J; Patel, NS; Rossi, A; Sautebin, L; Thiemermann, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collin, M | 1 |
| Rossi, A | 1 |
| Cuzzocrea, S | 1 |
| Patel, NS | 1 |
| Di Paola, R | 1 |
| Hadley, J | 1 |
| Collino, M | 1 |
| Sautebin, L | 1 |
| Thiemermann, C | 1 |
1 other study available for hydroxyurea and Endotoxemia
| Article | Year |
|---|---|
Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
Topics: Animals; Arachidonate 5-Lipoxygenase; CD11 Antigens; CD18 Antigens; Chemotaxis, Leukocyte; Disease M | 2004 |