Page last updated: 2024-10-28

hydroxyurea and Diarrhea

hydroxyurea has been researched along with Diarrhea in 7 studies

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
"Mucositis and diarrhea are the dose-limiting toxicities when continuous infusions of FUdR and high-dose folinic acid are combined with oral hydroxyurea, effects that are consistent with the observed toxicities for FUdR when administered alone or in combination with leucovorin."2.67Phase I study of 5-day continuous infusion fluorodeoxyuridine and high-dose folinic acid with oral hydroxyurea. ( Ahn, C; Akman, SA; Doroshow, JH; Leong, LA; Margolin, KA; Morgan, RJ; Newman, E; Raschko, JW; Somlo, G, 1994)
"Determine efficacy and adverse events (AEs) of hydroxyurea (HU) in mast cell activation syndrome (MCAS) patients who were refractory to standard medical therapy."1.72Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series. ( Brook, JB; Molderings, GJ; Weinstock, LB, 2022)
" During the subsequent 12 mo, the hydroxyurea dose adjusted according to follow-up CBC results, and finding an optimal dosage regimen proved to be challenging."1.43Diagnosis and Management of Polycythemia Vera in a Ferret ( ( Bassel, LL; Beaufrère, H; Blois, SL; Laniesse, D; Le, K; Smith, DA; Wills, S, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Weinstock, LB1
Brook, JB1
Molderings, GJ1
Le, K1
Beaufrère, H1
Bassel, LL1
Wills, S1
Laniesse, D1
Blois, SL1
Smith, DA1
Liu, AY1
Lowe, RC1
Levy, BD1
Katz, JT1
Loscalzo, J1
Reardon, DA1
Desjardins, A1
Vredenburgh, JJ1
Herndon, JE1
Coan, A1
Gururangan, S1
Peters, KB1
McLendon, R1
Sathornsumetee, S1
Rich, JN1
Lipp, ES1
Janney, D1
Friedman, HS1
Flexner, C1
Bartlett, JG1
Raschko, JW1
Akman, SA1
Leong, LA1
Margolin, KA1
Morgan, RJ1
Newman, E1
Somlo, G1
Ahn, C1
Doroshow, JH1
Rutschmann, OT1
Vernazza, PL1
Bucher, HC1
Opravil, M1
Ledergerber, B1
Telenti, A1
Malinverni, R1
Bernasconi, E1
Fagard, C1
Leduc, D1
Perrin, L1
Hirschel, B1

Trials

3 trials available for hydroxyurea and Diarrhea

ArticleYear
Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
    Cancer, 2012, Oct-01, Volume: 118, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2012
Phase I study of 5-day continuous infusion fluorodeoxyuridine and high-dose folinic acid with oral hydroxyurea.
    Cancer chemotherapy and pharmacology, 1994, Volume: 35, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

1994
Long-term hydroxyurea in combination with didanosine and stavudine for the treatment of HIV-1 infection. Swiss HIV Cohort Study.
    AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

    Topics: Anti-HIV Agents; Diarrhea; Didanosine; Drug Therapy, Combination; Enzyme Inhibitors; Follow-Up Studi

2000

Other Studies

4 other studies available for hydroxyurea and Diarrhea

ArticleYear
Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:11

    Topics: Abdominal Pain; Adult; Diarrhea; Female; Humans; Hydroxyurea; Mast Cell Activation Syndrome; Mast Ce

2022
Diagnosis and Management of Polycythemia Vera in a Ferret (
    Comparative medicine, 2016, 12-01, Volume: 66, Issue:6

    Topics: Animals; Antineoplastic Agents; Diarrhea; Erythropoietin; Fatal Outcome; Female; Ferrets; Hydroxyure

2016
Clinical problem-solving. A rash hypothesis.
    The New England journal of medicine, 2010, Jul-01, Volume: 363, Issue:1

    Topics: Adult; Biopsy; Blood Cell Count; Bone Marrow; Colon; Diagnosis, Differential; Diarrhea; Drug Therapy

2010
Complications of HIV therapy.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:2

    Topics: Acidosis, Lactic; Antiretroviral Therapy, Highly Active; Cardiovascular Diseases; Diarrhea; Drug The

2000