Page last updated: 2024-10-28

hydroxyurea and Cytomegalovirus

hydroxyurea has been researched along with Cytomegalovirus in 10 studies

Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.

Research Excerpts

ExcerptRelevanceReference
"Ganciclovir (GCV) is a deoxyguanosine analog that is effective in inhibiting human cytomegalovirus (HCMV) replication."7.79Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir. ( Bhave, S; Elford, H; McVoy, MA, 2013)
"Ganciclovir (GCV) is a deoxyguanosine analog that is effective in inhibiting human cytomegalovirus (HCMV) replication."3.79Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir. ( Bhave, S; Elford, H; McVoy, MA, 2013)
"Adult macaque Schwann cells were infected using adeno-associated virus type-2-derived vectors expressing the green fluorescent protein reporter gene under the control of the cytomegalovirus, the hybrid cytomegalovirus-betaactin, the myelin basic protein or the tetracycline-inducible promoters."3.73Efficiency of adeno-associated virus type-2 vectors in non-human primate Schwann cells. ( Attali, B; Bachelin, C; Baron-Van Evercooren, A; Chtarto, A; Girard, C; Lachapelle, F; Salvetti, A; Tenenbaum, L, 2005)
" The effect of several variables on the extent of AAV-mediated gene transfer was examined, including routes of delivery, presence of an underlying mutation that caused retinal degeneration, and prior treatment with hydroxyurea."3.69Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina. ( Grant, CA; Li, T; Ponnazhagan, S; Srivastava, A; Wang, XS, 1997)
"Results presented here show that when cytomegalovirus (strain Colburn)-infected cells are treated with the DNA synthesis inhibitor hydroxyurea or phosphonoformate, one type of intranuclear capsid accumulates."3.67Primate cytomegalovirus assembly: evidence that DNA packaging occurs subsequent to B capsid assembly. ( Gibson, W; Irmiere, A; Lee, JY, 1988)
"In conclusion, patients with acute myeloid leukemia receiving chemotherapy should be monitored for active CMV infection."1.36Prospective cytomegalovirus monitoring during first-line chemotherapy in patients with acute myeloid leukemia. ( Capobianchi, A; Capria, S; Cardarelli, L; Foà, R; Gentile, G; Gianfelici, V; Martino, P; Meloni, G; Trisolini, SM, 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhave, S1
Elford, H1
McVoy, MA1
Capria, S1
Gentile, G1
Capobianchi, A1
Cardarelli, L1
Gianfelici, V1
Trisolini, SM1
Foà, R1
Martino, P1
Meloni, G1
Opacić, N1
Barbarić, M1
Zorc, B1
Cetina, M1
Nagl, A1
Frković, D1
Kralj, M1
Pavelić, K1
Balzarini, J1
Andrei, G1
Snoeck, R1
De Clercq, E1
Raić-Malić, S1
Mintas, M1
Girard, C1
Tenenbaum, L1
Chtarto, A1
Attali, B1
Salvetti, A1
Bachelin, C1
Baron-Van Evercooren, A1
Lachapelle, F1
Sergiescu, D1
Sachs, MS1
Selker, EU1
Lin, B1
Roberts, CJ1
Luo, Z1
Vaught-Alexander, D1
Margolin, BS1
Grant, CA1
Ponnazhagan, S1
Wang, XS1
Srivastava, A1
Li, T1
Anuszewska, E1
Koziorowska, J1
Lee, JY1
Irmiere, A1
Gibson, W1
Ostendorf, P1
Ehninger, G1
Schmidt, H1
Haen, M1
Link, H1
Schüch, K1
Müller, C1
Wernet, P1
Dopfer, H1
Klingebiel, T1

Other Studies

10 other studies available for hydroxyurea and Cytomegalovirus

ArticleYear
Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.
    Antiviral research, 2013, Volume: 100, Issue:1

    Topics: Antiviral Agents; Benzamidines; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Drug Synergi

2013
Prospective cytomegalovirus monitoring during first-line chemotherapy in patients with acute myeloid leukemia.
    Journal of medical virology, 2010, Volume: 82, Issue:7

    Topics: Adult; Antibiotics, Antineoplastic; Antibodies, Viral; Antigens, Viral; Antineoplastic Agents; Antiv

2010
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Amino Acids; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Crystallography,

2005
Efficiency of adeno-associated virus type-2 vectors in non-human primate Schwann cells.
    Neuroreport, 2005, Nov-07, Volume: 16, Issue:16

    Topics: Analysis of Variance; Animals; Cell Count; Cell Proliferation; Cell Transplantation; Cells, Cultured

2005
Activation of an endogenous mouse type C virus by UV-irradiated murine cytomegalovirus.
    International journal of cancer, 1982, Apr-15, Volume: 29, Issue:4

    Topics: Animals; Cytomegalovirus; Dactinomycin; Hydroxyurea; Kirsten murine sarcoma virus; Mice; Mice, Inbre

1982
Expression of herpes virus thymidine kinase in Neurospora crassa.
    Nucleic acids research, 1997, Jun-15, Volume: 25, Issue:12

    Topics: Antiviral Agents; Bromodeoxyuridine; Cloning, Molecular; Cytomegalovirus; DNA Replication; Floxuridi

1997
Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina.
    Current eye research, 1997, Volume: 16, Issue:9

    Topics: Animals; Cytomegalovirus; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Hydroxyurea; Inje

1997
Characteristics of MNNG induced repair synthesis and DNA synthesis induced by human cytomegalovirus.
    Acta biochimica Polonica, 1989, Volume: 36, Issue:2

    Topics: Animals; Cells, Cultured; Cytarabine; Cytomegalovirus; DNA Repair; DNA, Viral; Humans; Hydroxyurea;

1989
Primate cytomegalovirus assembly: evidence that DNA packaging occurs subsequent to B capsid assembly.
    Virology, 1988, Volume: 167, Issue:1

    Topics: Capsid; Cells, Cultured; Centrifugation, Density Gradient; Cytomegalovirus; DNA, Viral; Electrophore

1988
[Bone marrow transplantation in chronic myeloid leukemia. Influence of gnotobiotic measures, especially antiviral prophylaxis].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-14, Volume: 111, Issue:7

    Topics: Acyclovir; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclos

1986