hydroxyurea has been researched along with Chromosome Deletion in 22 studies
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors present two patients with polycythemia vera where they recorded after several years' treatment with hydroxyurea development of acute myeloblastic leukaemia." | 7.70 | [Leukemic transformation of polycythemia vera after treatment with hydroxyurea and chromosome 17 abnormalities]. ( Fricová, M; Kafková, A; Nebesnáková, E; Stecová, N; Tóthová, E, 1999) |
| "Monosomy 7 variant childhood chronic myelogenous leukemia (CML) is a rare, fatal leukemia that usually terminates in blast crisis." | 5.28 | Establishment of donor hematopoiesis after hydroxyurea-induced aplasia following allograft failure in a patient with monosomy 7 variant of childhood chronic myelogenous leukemia. ( Cassano, WF, 1989) |
| "The authors present two patients with polycythemia vera where they recorded after several years' treatment with hydroxyurea development of acute myeloblastic leukaemia." | 3.70 | [Leukemic transformation of polycythemia vera after treatment with hydroxyurea and chromosome 17 abnormalities]. ( Fricová, M; Kafková, A; Nebesnáková, E; Stecová, N; Tóthová, E, 1999) |
| "The association of chronic lymphocytic leukemia (CLL) with essential thrombocythemia (ET) is an extremely rare event and until now 3 patients with such coexistence have been reported in the literature." | 2.42 | Coexistence of chronic lymphocytic leukemia and essential thrombocythemia. ( Bartkowiak, J; Góra-Tybor, J; Kordek, R; Korycka, A; Polliack, A; Robak, T; Urbańska-Ryś, H; Wawrzyniak, E, 2003) |
| "Hydroxyurea (HU) has been widely used in sickle cell disease." | 1.51 | Occurrence of acute myeloid leukemia in hydroxyurea-treated sickle cell disease patient. ( El-Deiry, WS; Finnberg, NK; Pu, JJ; Regan, S; Yang, X, 2019) |
| "Granulocytic sarcoma is very rare in essential thrombocythemia, and this patient may be the first reported case of essential thrombocythemia that developed multiple lesions and a pathologic fracture without transformation to overt leukemia." | 1.33 | Multiple granulocytic sarcomas in essential thrombocythemia. ( Fujita, H; Kurata, M; Maeda, A; Matsushita, A; Mori, M; Nagai, K; Nagai, Y; Takahashi, T; Tanaka, K; Tanaka, Y; Togami, K, 2006) |
| "Monosomy 7 variant childhood chronic myelogenous leukemia (CML) is a rare, fatal leukemia that usually terminates in blast crisis." | 1.28 | Establishment of donor hematopoiesis after hydroxyurea-induced aplasia following allograft failure in a patient with monosomy 7 variant of childhood chronic myelogenous leukemia. ( Cassano, WF, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Regan, S | 1 |
| Yang, X | 1 |
| Finnberg, NK | 1 |
| El-Deiry, WS | 1 |
| Pu, JJ | 1 |
| Xu, X | 1 |
| Xu, Y | 1 |
| Guo, R | 2 |
| Xu, R | 1 |
| Fu, C | 1 |
| Xing, M | 1 |
| Sasanuma, H | 1 |
| Li, Q | 1 |
| Takata, M | 1 |
| Takeda, S | 1 |
| Xu, D | 1 |
| Park, S | 1 |
| Hamel, JF | 1 |
| Toma, A | 1 |
| Kelaidi, C | 1 |
| Thépot, S | 1 |
| Campelo, MD | 1 |
| Santini, V | 1 |
| Sekeres, MA | 1 |
| Balleari, E | 1 |
| Kaivers, J | 1 |
| Sapena, R | 1 |
| Götze, K | 1 |
| Müller-Thomas, C | 1 |
| Beyne-Rauzy, O | 1 |
| Stamatoullas, A | 1 |
| Kotsianidis, I | 1 |
| Komrokji, R | 1 |
| Steensma, DP | 1 |
| Fensterl, J | 1 |
| Roboz, GJ | 1 |
| Bernal, T | 1 |
| Ramos, F | 1 |
| Calabuig, M | 1 |
| Guerci-Bresler, A | 1 |
| Bordessoule, D | 1 |
| Cony-Makhoul, P | 1 |
| Cheze, S | 1 |
| Wattel, E | 1 |
| Rose, C | 1 |
| Vey, N | 1 |
| Gioia, D | 1 |
| Ferrero, D | 1 |
| Gaidano, G | 1 |
| Cametti, G | 1 |
| Pane, F | 1 |
| Sanna, A | 1 |
| Germing, U | 1 |
| Sanz, GF | 1 |
| Dreyfus, F | 1 |
| Fenaux, P | 1 |
| Tiziana Storlazzi, C | 1 |
| Pieri, L | 1 |
| Paoli, C | 1 |
| Daniele, G | 1 |
| Lasho, T | 1 |
| Tefferi, A | 1 |
| Vannucchi, AM | 1 |
| Ziarkiewicz, M | 1 |
| Dwilewicz-Trojaczek, J | 1 |
| Pastwińska, A | 1 |
| Chmarzyńska, E | 1 |
| Paszkowska-Kowalewska, M | 1 |
| Koperski, Ł | 1 |
| Jędrzejczak, WW | 1 |
| Ziarkiewicz-Wróblewska, B | 1 |
| Bennour, A | 1 |
| Ouahchi, I | 1 |
| Ben Youssef, Y | 1 |
| Zaier, M | 1 |
| Laatiri, MA | 1 |
| Harrabi, I | 1 |
| Meddeb, B | 1 |
| Elloumi, M | 1 |
| Khelif, A | 1 |
| Saad, A | 1 |
| Sennana, H | 1 |
| Robak, T | 1 |
| Urbańska-Ryś, H | 1 |
| Góra-Tybor, J | 1 |
| Wawrzyniak, E | 1 |
| Korycka, A | 1 |
| Bartkowiak, J | 1 |
| Kordek, R | 1 |
| Polliack, A | 1 |
| Candoni, A | 1 |
| Tiribelli, M | 1 |
| Fanin, R | 1 |
| Barbera, MA | 1 |
| Petes, TD | 1 |
| Tanaka, Y | 1 |
| Nagai, Y | 1 |
| Mori, M | 1 |
| Fujita, H | 1 |
| Togami, K | 1 |
| Kurata, M | 1 |
| Matsushita, A | 1 |
| Maeda, A | 1 |
| Nagai, K | 1 |
| Tanaka, K | 1 |
| Takahashi, T | 1 |
| Hirri, HM | 1 |
| Green, PJ | 1 |
| Tóthová, E | 1 |
| Nebesnáková, E | 1 |
| Kafková, A | 1 |
| Stecová, N | 1 |
| Fricová, M | 1 |
| Sutton, A | 1 |
| Bucaria, J | 1 |
| Osley, MA | 1 |
| Sternglanz, R | 1 |
| Hartsuiker, E | 1 |
| Vaessen, E | 1 |
| Carr, AM | 1 |
| Kohli, J | 1 |
| Wan, J | 1 |
| Xu, H | 1 |
| Grunstein, M | 1 |
| Daikoku, T | 1 |
| Yamamoto, N | 1 |
| Maeno, K | 1 |
| Nishiyama, Y | 1 |
| Von Hoff, DD | 1 |
| Waddelow, T | 1 |
| Forseth, B | 1 |
| Davidson, K | 1 |
| Scott, J | 1 |
| Wahl, G | 1 |
| Provan, A | 1 |
| Majer, RV | 1 |
| Herbert, A | 1 |
| Smith, AG | 1 |
| Derr, LK | 1 |
| Drake, JW | 1 |
| Cassano, WF | 1 |
| Preston, VG | 1 |
| Darling, AJ | 1 |
| McDougall, IM | 1 |
| Hecht, F | 1 |
| Morgan, R | 1 |
| Schrier, SL | 1 |
| Adams, J | 1 |
| Sandberg, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Integrated European Platform to Conduct Translational Studies in Myelodysplastic Syndromes Based on the EuroBloodNet Infrastructure[NCT04174547] | 8,670 participants (Anticipated) | Observational | 2019-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydroxyurea and Chromosome Deletion
| Article | Year |
|---|---|
Coexistence of chronic lymphocytic leukemia and essential thrombocythemia.
Topics: Aged; Chromosome Deletion; Chromosomes, Human, Pair 13; Clone Cells; Cytogenetic Analysis; Diagnosis | 2003 |
Plasma cell leukemia occurring in a patient with thrombocythemia treated with hydroxyurea and busulphan.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe | 2004 |
20 other studies available for hydroxyurea and Chromosome Deletion
| Article | Year |
|---|---|
Occurrence of acute myeloid leukemia in hydroxyurea-treated sickle cell disease patient.
Topics: Adult; Anemia, Sickle Cell; Carcinogenesis; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromo | 2019 |
Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.
Topics: Aneuploidy; Animals; Bone Marrow Failure Disorders; Cell Line, Transformed; Chickens; Chromosome Bre | 2021 |
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; | 2017 |
Complex karyotype in a polycythemia vera patient with a novel SETD1B/GTF2H3 fusion gene.
Topics: Chromosome Deletion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 6; Combined Modality Ther | 2014 |
Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) with superimposed 5q-syndrome.
Topics: Aged; Anemia, Macrocytic; Anemia, Refractory; Anemia, Sideroblastic; Antineoplastic Agents; Bone Mar | 2010 |
Molecular cytogenetic study of derivative chromosome 9 deletion in chronic myeloid leukemia patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosome Deletion; Chromosomes, | 2012 |
Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae.
Topics: Centromere; Chromosome Deletion; Chromosomes, Fungal; Crossing Over, Genetic; Heterozygote; Hydroxyu | 2006 |
Multiple granulocytic sarcomas in essential thrombocythemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Chromosome Deletion; Chromosomes, | 2006 |
Pure red cell aplasia in a patient with chronic granulocytic leukaemia treated with interferon-alpha.
Topics: Aged; Anemia; Blood Transfusion; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 22; Huma | 2000 |
[Leukemic transformation of polycythemia vera after treatment with hydroxyurea and chromosome 17 abnormalities].
Topics: Chromosome Deletion; Chromosomes, Human, Pair 17; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Ac | 1999 |
Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription.
Topics: Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Separation; Chromatin; Chroma | 2001 |
Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Cycle Pr | 2001 |
CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle.
Topics: Amino Acid Sequence; Base Sequence; Cell Cycle; Cell Cycle Proteins; Chromosome Deletion; Cloning, M | 1992 |
Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells.
Topics: Animals; Chromosome Deletion; Floxuridine; Hydroxyurea; Kinetics; Phosphorylation; Ribonucleotide Re | 1991 |
Hydroxyurea accelerates loss of extrachromosomally amplified genes from tumor cells.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); | 1991 |
del(15)(q11q15) associated with transformation of chronic myelomonocytic leukemia.
Topics: Aged; Blood Transfusion; Chromosome Deletion; Chromosomes, Human, Pair 15; Humans; Hydroxyurea; Kary | 1991 |
Isolation and genetic characterization of new uvsW alleles of bacteriophage T4.
Topics: Alleles; Chromosome Deletion; DNA Repair; DNA Replication; DNA, Viral; Genes, Dominant; Genes, Viral | 1990 |
Establishment of donor hematopoiesis after hydroxyurea-induced aplasia following allograft failure in a patient with monosomy 7 variant of childhood chronic myelogenous leukemia.
Topics: Bone Marrow; Bone Marrow Transplantation; Chimera; Chromosome Deletion; Chromosomes, Human, Pair 7; | 1989 |
The herpes simplex virus type 1 temperature-sensitive mutant ts1222 has a single base pair deletion in the small subunit of ribonucleotide reductase.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; Culture Media; DNA, Viral; Genes, Viral; Hy | 1988 |
The Philadelphia (Ph) chromosome in leukemia. I. A new mechanism due to interstitial deletion and insertion in chronic myelocytic leukemia.
Topics: Bone Marrow; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, 21-22 and Y; Chromosomes, | 1985 |