hydroxyurea has been researched along with Chromosome-Defective Micronuclei in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, L | 1 |
| Zhao, Y | 1 |
| Quan, C | 1 |
| Ji, W | 1 |
| Zhu, J | 1 |
| Huang, Y | 1 |
| Guan, R | 1 |
| Sun, D | 1 |
| Jin, Y | 1 |
| Meng, X | 1 |
| Zhang, C | 1 |
| Yu, Y | 1 |
| Bai, J | 1 |
| Sun, W | 1 |
| Fu, S | 1 |
| Álvarez-González, I | 1 |
| Vázquez-Sánchez, J | 1 |
| Chamorro-Cevallos, G | 1 |
| Madrigal-Bujaidar, E | 1 |
| Flanagan, JM | 1 |
| Howard, TA | 1 |
| Mortier, N | 1 |
| Avlasevich, SL | 1 |
| Smeltzer, MP | 1 |
| Wu, S | 1 |
| Dertinger, SD | 1 |
| Ware, RE | 1 |
| Utani, K | 1 |
| Kohno, Y | 1 |
| Okamoto, A | 1 |
| Shimizu, N | 3 |
| Xu, B | 1 |
| Sun, Z | 1 |
| Liu, Z | 1 |
| Guo, H | 1 |
| Liu, Q | 1 |
| Jiang, H | 1 |
| Zou, Y | 1 |
| Gong, Y | 1 |
| Tischfield, JA | 1 |
| Shao, C | 1 |
| Wakabayashi, M | 1 |
| Saijyou, N | 1 |
| Hatakeyama, S | 1 |
| Inoue, H | 1 |
| Tanaka, S | 1 |
| Valovicová, Z | 1 |
| Gábelová, A | 1 |
| Husøy, T | 1 |
| Abramsson-Zetterberg, L | 1 |
| Ølstørn, HB | 1 |
| Paulsen, JE | 1 |
| Alexander, J | 1 |
| Fenech, M | 1 |
| Rinaldi, J | 1 |
| Surralles, J | 1 |
| Kanda, T | 1 |
| Wahl, GM | 1 |
| Hirano, T | 1 |
| Shiraishi, K | 1 |
| Adachi, K | 1 |
| Miura, S | 1 |
| Watanabe, H | 1 |
| Utiyama, H | 1 |
| Tanaka, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease[NCT00305175] | 260 participants (Actual) | Observational | 2006-03-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxyurea and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Assessment of genotoxicity associated with hydroxyurea therapy in children with sickle cell anemia.
Topics: Adolescent; Anemia, Sickle Cell; Antisickling Agents; Child; Child, Preschool; DNA Damage; Humans; H | 2010 |
11 other studies available for hydroxyurea and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; DNA Damage; DNA, Neoplas | 2013 |
Effect of Spirulina maxima and its protein extract on micronuclei induction by hydroxyurea in pregnant mice and their fetuses.
Topics: Animals; Antimutagenic Agents; DNA Damage; Dose-Response Relationship, Drug; Erythrocytes; Female; F | 2013 |
Emergence of micronuclei and their effects on the fate of cells under replication stress.
Topics: Apoptosis; HeLa Cells; Humans; Hydroxyurea; Kinetics; Micronuclei, Chromosome-Defective; Microscopy; | 2010 |
Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.
Topics: Animals; Aphidicolin; Cell Line; DNA Breaks, Double-Stranded; DNA Replication; Histones; Humans; Hyd | 2011 |
Neurospora mrc1 homologue is involved in replication stability and is required for normal cell growth and chromosome integrity in mus-9 and mus-21 mutants.
Topics: Cell Cycle; Chromosomal Instability; DNA Damage; DNA Repair; DNA Replication; DNA, Fungal; Fungal Pr | 2012 |
Effect of cytosine arabinoside and hydroxyurea on micronucleus formation induced by model clastogens in Chinese hamster V79 cells.
Topics: Animals; Cricetinae; Cricetulus; Cytarabine; Hydroxyurea; Micronuclei, Chromosome-Defective; Micronu | 2004 |
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cyt | 2005 |
The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes.
Topics: Adult; Cytarabine; DNA Damage; DNA Repair; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; | 1994 |
Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA.
Topics: Cell Fractionation; Centromere; Chromosome Aberrations; DNA Probes; Enzyme Inhibitors; Gene Amplific | 1996 |
Co-localization of mitochondrial and double minute DNA in the nuclei of HL-60 cells but not normal cells.
Topics: Cell Cycle; Cell Nucleus; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA Damage; DNA, Mitoc | 1999 |
Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase.
Topics: Chromatin; Chromosomes; Cytoplasm; DNA Replication; G1 Phase; Humans; Hydroxyurea; Lamins; Micronucl | 2000 |