Page last updated: 2024-10-28

hydroxyurea and Chromosomal Translocation

hydroxyurea has been researched along with Chromosomal Translocation in 41 studies

Research Excerpts

ExcerptRelevanceReference
"Imatinib mesylate has been reported to produce positive results in atypical chronic myeloproliferative disorders (CMD) with chromosomal translocations that disrupt the platelet-derived growth factor receptor beta gene (PDGFRB)."3.72Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene. ( Bastie, JN; Castaigne, S; Cross, NC; Garcia, I; Mahon, FX; Terré, C, 2004)
"Myelodysplastic syndrome with chromosomal translocation t(5;12)(q31-33;p12-13) and eosinophilia is a new entity recently described."2.39Myelodysplastic syndrome with t(5;12)(q31;p12-p13) and eosinophilia: a pediatric case with review of literature. ( Baranger, L; Blanchet, O; François, S; Ifrah, N; Larget-Piet, L; Le Moine, PJ; Pellier, I; Rialland, X, 1996)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19906 (14.63)18.7374
1990's10 (24.39)18.2507
2000's16 (39.02)29.6817
2010's9 (21.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, SH1
Chi, HS1
Cho, YU1
Jang, S1
Park, CJ1
Kim, DY1
Lee, JH1
Lee, KH1
Grisouard, J1
Ojeda-Uribe, M1
Looser, R1
Hao-Shen, H1
Lundberg, P1
Duek, A1
Jeandidier, E1
Karow, A1
Skoda, RC1
Tiziana Storlazzi, C1
Pieri, L1
Paoli, C1
Daniele, G1
Lasho, T1
Tefferi, A1
Vannucchi, AM1
Matsumura, I1
McGrattan, P1
Humphreys, M1
Hull, D1
Goto, H1
Hara, T1
Tsurumi, H1
Tanabashi, S1
Moriwaki, H1
Schlisser, AE1
Yan, J1
Hales, BF1
Belli, C1
Alú, MF1
Alfonso, G1
Bianchini, M1
Larripa, I1
Bennour, A1
Ouahchi, I1
Ben Youssef, Y1
Zaier, M1
Laatiri, MA1
Harrabi, I1
Meddeb, B1
Elloumi, M1
Khelif, A1
Saad, A1
Sennana, H1
Prochorec-Sobieszek, M1
Nasiłowska-Adamska, B1
Borg, K1
Kopeć, I1
Kos-Zakrzewska, K1
Juszczyński, P1
Warzocha, K1
Yeung, SC1
Elsayem, A1
Fuller, GN1
Lu, G1
You, MJ1
Royer-Pokora, B1
Hildebrandt, B1
Redmann, A1
Herold, C1
Kronenwett, R1
Haas, R1
Drechsler, M1
Wieland, C1
Bastie, JN1
Garcia, I1
Terré, C1
Cross, NC2
Mahon, FX1
Castaigne, S1
Curtin, NJ1
Campbell, PJ1
Green, AR1
Huang, Q1
Bousquet, M1
Quelen, C1
De Mas, V1
Duchayne, E1
Roquefeuil, B1
Delsol, G1
Laurent, G1
Dastugue, N1
Brousset, P1
Chim, CS1
Ma, SK1
Rudolph, G1
Haritoglou, C1
Schmid, I1
Hochhaus, F1
Kampik, A1
Yin, CC1
Cortes, J1
Barkoh, B1
Hayes, K1
Kantarjian, H1
Jones, D1
Cesar, JM1
Cabello, P2
Ferro, T2
Navarro, JL1
Grand, FH1
Iqbal, S1
Zhang, L1
Russell, NH1
Chase, A1
Dahabreh, IJ1
Giannouli, S1
Zoi, C1
Zoi, K1
Voulgarelis, M1
Moutsopoulos, HM1
van Buul, PP2
Bootsma, AL1
Inhorn, RC1
Aster, JC1
Roach, SA1
Slapak, CA1
Soiffer, R1
Tantravahi, R1
Stone, RM1
Berger, R1
Hillion, J1
Janvier, D1
Chen, Z1
Bussel, A1
Uriarte, MR1
Mori, MA1
de Bellis, R1
Cardoso, H1
Sato, H1
Saito, H1
Ikebuchi, K1
Danbara, M1
Yagisawa, M1
Yuo, A1
Pellier, I1
Le Moine, PJ1
Rialland, X1
François, S1
Baranger, L1
Blanchet, O1
Larget-Piet, L1
Ifrah, N1
Gudi, R1
Elizalde, A1
Gogineni, SK1
Macera, MJ1
Badillo, A1
Verma, RS1
Jacob, A1
Griffiths, M1
Larkins, S1
Holmes, J1
Tanaka, M1
Yamazaki, Y1
Kondo, E1
Hattori, M1
Tsushita, K1
Utsumi, M1
Oudat, R1
Khan, Z1
Glassman, AB1
Krsnik, I1
García Suárez, J1
Vázquez Mazariego, Y1
Zhou, B1
Mo, X1
Liu, X1
Qiu, W1
Yen, Y1
Brinkley, BR1
Hittelman, WN1
Whang-Peng, J1
Broder, S1
Lee, E1
Young, RC1
Goudzwaard, JH1
Champlin, RE1
Golde, DW1
Hecht, F1
Morgan, R1
Schrier, SL1
Adams, J1
Sandberg, AA1
Griffin, JD1
Wauben-Penris, PJ1
van Meel, GP1
de Boer, P1

Reviews

8 reviews available for hydroxyurea and Chromosomal Translocation

ArticleYear
[Treatment of chronic myeloid leukemia in chronic phase].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Allografts; Benzamides; Busulfan; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Dasatinib

2014
Simultaneous occurrence of a t(9;22) (Ph) with a t(2;11) in a patient with CML and emergence of a new clone with the t(2;11) alone after imatinib mesylate treatment.
    Leukemia, 2003, Volume: 17, Issue:4

    Topics: Antineoplastic Agents; Benzamides; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 2; Clinical

2003
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
    Blood, 1995, Apr-01, Volume: 85, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Prot

1995
Myelodysplastic syndrome with t(5;12)(q31;p12-p13) and eosinophilia: a pediatric case with review of literature.
    Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:3

    Topics: Adult; Child; Chromosome Mapping; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 5; Eosinophi

1996
Characterization of a complex translocation [t(4;9;22)(p16;q34;q11)] in chronic myelogenous leukemia by fluorescence in situ hybridization technique.
    Cancer genetics and cytogenetics, 1996, Volume: 90, Issue:2

    Topics: Allopurinol; Antineoplastic Agents; Bone Marrow; Busulfan; Chromosome Banding; Chromosome Mapping; C

1996
Ultrastructure of mammalian chromosome aberrations.
    International review of cytology, 1975, Volume: 42

    Topics: Alkylating Agents; Aminopterin; Animals; Bleomycin; Cell Line; Cell Nucleolus; Cells, Cultured; Chro

1975
Chronic myelogenous leukemia: recent advances.
    Blood, 1985, Volume: 65, Issue:5

    Topics: Bone Marrow Transplantation; Busulfan; Cell Transformation, Neoplastic; Chromosomes, Human, 21-22 an

1985
Management of chronic myelogenous leukemia.
    Seminars in hematology, 1986, Volume: 23, Issue:3 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Hematopoiesis

1986

Trials

1 trial available for hydroxyurea and Chromosomal Translocation

ArticleYear
Management of hypereosinophilic syndrome: a prospective study in the era of molecular genetics.
    Medicine, 2007, Volume: 86, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyto

2007

Other Studies

32 other studies available for hydroxyurea and Chromosomal Translocation

ArticleYear
Two cases of myeloproliferative neoplasm with a concurrent JAK2 (V617F) mutation and BCR/ABL translocation without chronic myelogenous leukemia phenotype acquisition during hydroxyurea treatment.
    Annals of laboratory medicine, 2013, Volume: 33, Issue:3

    Topics: Adult; Alleles; Fusion Proteins, bcr-abl; Heterozygote; Humans; Hydroxyurea; Janus Kinase 2; Leukemi

2013
Complex subclone structure that responds differentially to therapy in a patient with essential thrombocythemia and chronic myeloid leukemia.
    Blood, 2013, Nov-21, Volume: 122, Issue:22

    Topics: Clone Cells; Dasatinib; Female; Genes, abl; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myelogeno

2013
Complex karyotype in a polycythemia vera patient with a novel SETD1B/GTF2H3 fusion gene.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Chromosome Deletion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 6; Combined Modality Ther

2014
Unbalanced jumping translocation involving 3q in myeloproliferative disease.
    Medical oncology (Northwood, London, England), 2009, Volume: 26, Issue:2

    Topics: Aged, 80 and over; Bronchopneumonia; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 3; Chromo

2009
Chronic neutrophilic leukemia with congenital Robertsonian translocation successfully treated with allogeneic bone marrow transplantation in a young man.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:7

    Topics: Bone Marrow Transplantation; Cell Transformation, Neoplastic; Chromosome Disorders; Chromosomes, Hum

2009
Teratogen-induced oxidative stress targets glyceraldehyde-3-phosphate dehydrogenase in the organogenesis stage mouse embryo.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Abnormalities, Drug-Induced; Aldehydes; Animals; Aspartate Aminotransferase, Mitochondrial; Cell Nuc

2010
Novel variant Ph translocation t(9;22;11)(q34;q11.2;p15)inv(9)(p13q34) in chronic myeloid leukemia involving a one-step mechanism.
    Cytogenetic and genome research, 2011, Volume: 132, Issue:4

    Topics: Aged; Antineoplastic Agents; Benzamides; Chromosome Banding; Chromosome Inversion; Chromosomes, Huma

2011
Molecular cytogenetic study of derivative chromosome 9 deletion in chronic myeloid leukemia patients.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosome Deletion; Chromosomes,

2012
Chronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) with PCM1-JAK2 fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target?
    Leukemia & lymphoma, 2012, Volume: 53, Issue:9

    Topics: Antineoplastic Agents; Cell Proliferation; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; C

2012
Fatal acute monocytic leukaemia with t(6;11) (q27;q23) translocation and KRAS mutation.
    Journal of clinical pathology, 2013, Volume: 66, Issue:1

    Topics: Antineoplastic Agents; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 6; Fatal Outcome; Human

2013
Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene.
    Haematologica, 2004, Volume: 89, Issue:10

    Topics: Benzamides; Biomarkers; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 5; Disease Progression

2004
The Philadelphia translocation and pre-existing myeloproliferative disorders.
    British journal of haematology, 2005, Volume: 128, Issue:5

    Topics: Antineoplastic Agents; Benzamides; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myelogenous, Ch

2005
Chronic myelogenous leukemia in accelerated phase.
    Archives of pathology & laboratory medicine, 2005, Volume: 129, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzamides; Chromosome

2005
The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene.
    Oncogene, 2005, Nov-03, Volume: 24, Issue:48

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Autoantigens; C

2005
Der(8)t(1;8) in myeloblastic transformation of ET with hydroxyurea as the sole prior treatment.
    Hematological oncology, 2005, Volume: 23, Issue:2

    Topics: Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Hu

2005
Visual loss as a first sign of adult-type chronic myeloid leukemia in a child.
    American journal of ophthalmology, 2005, Volume: 140, Issue:4

    Topics: Blindness; Blood Cell Count; Child; Fluorescein Angiography; Hematopoietic Stem Cell Transplantation

2005
t(3;21)(q26;q22) in myeloid leukemia: an aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy.
    Cancer, 2006, Apr-15, Volume: 106, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bone Marrow; Chromosomes, Human

2006
Emergence of chronic myelogenous leukemia in a patient with primary thrombocythemia and absence of BCR/ABL rearrangement.
    Cancer genetics and cytogenetics, 2006, Volume: 167, Issue:1

    Topics: Aged; Antineoplastic Agents; Benzamides; Blood Platelets; Bone Marrow Cells; Cells, Cultured; Chromo

2006
A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.
    Experimental hematology, 2007, Volume: 35, Issue:11

    Topics: Adult; Bone Marrow Transplantation; Female; fms-Like Tyrosine Kinase 3; Humans; Hydroxyurea; Immunot

2007
The induction of chromosomal damage and cell killing in mouse spermatogonial stem cells following combined treatments with hydroxyurea, 3-aminobenzamide and X-rays.
    Mutation research, 1994, Dec-01, Volume: 311, Issue:2

    Topics: Animals; Benzamides; Cell Death; DNA Repair; G1 Phase; Hydroxyurea; Male; Mice; Radiation Tolerance;

1994
t(8;21) prior to acute leukemia.
    Cancer genetics and cytogenetics, 1993, Oct-15, Volume: 70, Issue:2

    Topics: Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Female; Humans; Hydroxyurea; Leukemia, Myel

1993
Remission of Philadelphia positive chronic myelogenous leukemia associated with t(3;21) after bone marrow transplantation.
    Cancer genetics and cytogenetics, 1993, Jul-15, Volume: 68, Issue:2

    Topics: Adult; Blotting, Southern; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Chromosomes, Human,

1993
Biological characteristics of chronic eosinophilic leukemia cells with a t(2;5)(p23;q35) translocation.
    Leukemia & lymphoma, 1995, Volume: 19, Issue:5-6

    Topics: Adult; Antigens, Neoplasm; Antigens, Surface; Chemotactic Factors; Chemotaxis, Leukocyte; Chromosome

1995
t(3;21) following peripheral blood stem cell transplantation in chronic phase chronic myeloid leukaemia.
    Bone marrow transplantation, 1997, Volume: 19, Issue:12

    Topics: Adult; Antineoplastic Agents; Chromosome Banding; Chromosomes, Human, Pair 21; Chromosomes, Human, P

1997
Achievement of a complete cytogenetic response with hydroxyurea in a patient with chronic myelogenous leukemia.
    Leukemia research, 1997, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow; Chromosome Mapping; Chromosomes, Human, Pair 22; Chromosomes, Hu

1997
A unique, complex variant philadelphia chromosome translocation in a patient with typical chronic myelogenous leukemia.
    Archives of pathology & laboratory medicine, 2001, Volume: 125, Issue:3

    Topics: Adult; Antineoplastic Agents; Chromosome Painting; Humans; Hydroxyurea; Karyotyping; Leukemia, Myelo

2001
Translocation t(4; 6)(q21; q27) in a case of primary thrombocythaemia in transformation.
    Clinical and laboratory haematology, 2001, Volume: 23, Issue:4

    Topics: Aged; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 6; Fatal

2001
Human ribonucleotide reductase M2 subunit gene amplification and transcriptional regulation in a homogeneous staining chromosome region responsible for the mechanism of drug resistance.
    Cytogenetics and cell genetics, 2001, Volume: 95, Issue:1-2

    Topics: Chromosome Banding; Chromosomes, Human, Pair 2; Deoxycytidine; DNA; Drug Resistance; Electrophoretic

2001
Unusual clonal evolution in a case of chronic myelogenous leukemia.
    Acta haematologica, 1976, Volume: 56, Issue:6

    Topics: Adult; Chromosome Aberrations; Clone Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Translocat

1976
The relation between induced reciprocal translocations and cell killing of mouse spermatogonial stem cells after combined treatments with hydroxyurea and X-rays.
    Mutation research, 1990, Volume: 243, Issue:4

    Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Hydroxyurea; Male; Mice; Organ Size;

1990
The Philadelphia (Ph) chromosome in leukemia. I. A new mechanism due to interstitial deletion and insertion in chronic myelocytic leukemia.
    Cancer genetics and cytogenetics, 1985, Jan-01, Volume: 14, Issue:1-2

    Topics: Bone Marrow; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, 21-22 and Y; Chromosomes,

1985
Spermatogenic delay and increased chiasma frequency in T70H/+ male mice with hydroxyurea-Trenimon limited spermatocyte populations.
    Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie, 1985, Volume: 27, Issue:2

    Topics: Animals; Autoradiography; Hydroxyurea; Karyotyping; Male; Metaphase; Mice; Recombination, Genetic; S

1985