hydroxyurea has been researched along with Chromosomal Breakage in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has long been believed that chromosomal breaks are always associated with double-strand breaks (DSBs)." | 1.39 | Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks. ( Adachi, N; Fujita, M; Harada, H; Hiraoka, M; Hirota, K; Kurosawa, A; Omura, M; Sasanuma, H; Takeda, S; Yamamoto, KN, 2013) |
| "Bloom Syndrome is an autosomal recessive cancer-prone disorder caused by mutations in the BLM gene." | 1.35 | BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome. ( Ali, AM; Andreassen, PR; Busygina, V; Du, CH; Fan, Q; Meetei, AR; Raynard, S; Singh, TR; Sung, P, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, X | 1 |
| Xu, Y | 1 |
| Guo, R | 2 |
| Xu, R | 1 |
| Fu, C | 1 |
| Xing, M | 1 |
| Sasanuma, H | 2 |
| Li, Q | 1 |
| Takata, M | 1 |
| Takeda, S | 2 |
| Xu, D | 1 |
| Fujita, M | 1 |
| Yamamoto, KN | 1 |
| Harada, H | 1 |
| Kurosawa, A | 1 |
| Adachi, N | 1 |
| Omura, M | 1 |
| Hiraoka, M | 1 |
| Hirota, K | 1 |
| Hu, L | 1 |
| Kim, TM | 1 |
| Son, MY | 1 |
| Kim, SA | 1 |
| Holland, CL | 1 |
| Tateishi, S | 1 |
| Kim, DH | 1 |
| Yew, PR | 1 |
| Montagna, C | 1 |
| Dumitrache, LC | 1 |
| Hasty, P | 1 |
| Cauwood, JD | 1 |
| Johnson, AL | 1 |
| Widger, A | 1 |
| Cha, RS | 2 |
| Hoffman, EA | 1 |
| McCulley, A | 1 |
| Haarer, B | 1 |
| Arnak, R | 1 |
| Feng, W | 2 |
| Singh, TR | 1 |
| Ali, AM | 1 |
| Busygina, V | 1 |
| Raynard, S | 1 |
| Fan, Q | 1 |
| Du, CH | 1 |
| Andreassen, PR | 1 |
| Sung, P | 1 |
| Meetei, AR | 1 |
| Bachant, J | 1 |
| Collingwood, D | 1 |
| Raghuraman, MK | 1 |
| Brewer, BJ | 1 |
| Kleckner, N | 1 |
| de Lahondès, R | 1 |
| Ribes, V | 1 |
| Arcangioli, B | 1 |
| Han, J | 1 |
| Zhou, H | 1 |
| Horazdovsky, B | 1 |
| Zhang, K | 1 |
| Xu, RM | 1 |
| Zhang, Z | 1 |
| Freudenreich, CH | 1 |
| Kantrow, SM | 1 |
| Zakian, VA | 1 |
| Johnstone, P | 1 |
| Reifsteck, C | 1 |
| Kohler, S | 1 |
| Worland, P | 1 |
| Olson, S | 1 |
| Moses, RE | 1 |
| Filatov, MV | 1 |
| Pantina, RA | 1 |
| Noskin, LA | 1 |
13 other studies available for hydroxyurea and Chromosomal Breakage
| Article | Year |
|---|---|
Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.
Topics: Aneuploidy; Animals; Bone Marrow Failure Disorders; Cell Line, Transformed; Chickens; Chromosome Bre | 2021 |
Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks.
Topics: Animals; Antigens, Nuclear; Aphidicolin; Apoptosis; Cell Line, Tumor; Chickens; Chromosome Breakage; | 2013 |
Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.
Topics: Animals; Base Sequence; Chromosomal Instability; Chromosome Breakage; Chromosomes, Mammalian; DNA Br | 2013 |
Recombinogenic conditions influence partner choice in spontaneous mitotic recombination.
Topics: Chromosome Breakage; Chromosome Fragile Sites; DNA Replication; Hydroxyurea; Mitosis; Mutation; Reco | 2013 |
Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription.
Topics: Cell Cycle; Chromosome Breakage; Chromosome Fragility; DNA Breaks, Double-Stranded; DNA Replication; | 2015 |
BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome.
Topics: Amino Acid Sequence; Animals; Bloom Syndrome; Bone Neoplasms; Carrier Proteins; Cell Nucleus; Cells, | 2008 |
Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress.
Topics: Alleles; Cell Cycle Proteins; Cell Survival; Centromere; Checkpoint Kinase 2; Chromosome Breakage; C | 2009 |
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.
Topics: Chromosome Breakage; Chromosomes, Fungal; DNA Replication; DNA, Fungal; Fungal Proteins; G1 Phase; G | 2002 |
Fission yeast Sap1 protein is essential for chromosome stability.
Topics: Anaphase; Benzimidazoles; Blotting, Southern; Blotting, Western; Cell Division; Centromere; Chromati | 2003 |
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.
Topics: Acetylation; Amino Acid Sequence; Camptothecin; Catalytic Domain; Chromosome Breakage; DNA Damage; D | 2007 |
Expansion and length-dependent fragility of CTG repeats in yeast.
Topics: Chromosome Breakage; Chromosome Fragility; Chromosomes, Fungal; DNA Damage; DNA Repair; DNA Replicat | 1998 |
Fanconi anemia group A and D cell lines respond normally to inhibitors of cell cycle regulation.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Cell Cycle; Cells, Culture | 1997 |
Methods for registration of spontaneous DNA instability in mammalian cells.
Topics: Benzimidazoles; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Chromosome Breakage; Cytarabine; DNA | 1998 |