hydroxyurea has been researched along with Chagas Disease in 4 studies
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trypanosoma cruzi, etiological agent of Chagas' disease, has a complex life cycle which involves the invasion of mammalian host cells, differentiation and intracellular replication." | 1.39 | Host cell poly(ADP-ribose) glycohydrolase is crucial for Trypanosoma cruzi infection cycle. ( Alonso, GD; Fernández Villamil, SH; Flawiá, MM; Kevorkian, ML; Schlesinger, M; Vilchez Larrea, SC, 2013) |
| "Thymidine incorporation was somewhat inhibited when the diterpene was added at 12 h after removal of hydroxyurea, possibly on the transition S/G2." | 1.38 | The effect of the diterpene 5-epi-icetexone on the cell cycle of Trypanosoma cruzi. ( Barrera, P; Lozano, E; Nieto, M; Sartor, T; Sosa, MA; Tonn, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vilchez Larrea, SC | 1 |
| Schlesinger, M | 1 |
| Kevorkian, ML | 1 |
| Flawiá, MM | 1 |
| Alonso, GD | 1 |
| Fernández Villamil, SH | 1 |
| Lozano, E | 1 |
| Barrera, P | 1 |
| Tonn, C | 1 |
| Nieto, M | 1 |
| Sartor, T | 1 |
| Sosa, MA | 1 |
| Lopes, LM | 1 |
| Pereira, MA | 1 |
| Gerken, SE | 1 |
| Vaz, N | 1 |
| Fucs, R | 1 |
| Barcinski, MA | 1 |
4 other studies available for hydroxyurea and Chagas Disease
| Article | Year |
|---|---|
Host cell poly(ADP-ribose) glycohydrolase is crucial for Trypanosoma cruzi infection cycle.
Topics: Adenosine Diphosphate; Animals; Blotting, Northern; Blotting, Southern; Blotting, Western; Catalysis | 2013 |
The effect of the diterpene 5-epi-icetexone on the cell cycle of Trypanosoma cruzi.
Topics: Cell Cycle; Chagas Disease; Diterpenes; Humans; Hydroxyurea; Thymidine; Time Factors; Trypanosoma cr | 2012 |
Polyclonal activation of B lymphocytes during experimental infection with Schistosoma mansoni.
Topics: Animals; Antigens, Helminth; B-Lymphocytes; Chagas Disease; Hydroxyurea; Immunity, Cellular; Immuniz | 1990 |
Effect of hydroxyurea on the concanavalin-A proliferative response of Trypanosoma cruzi infected mice.
Topics: Animals; Chagas Disease; Concanavalin A; Female; Hydroxyurea; Interleukin-2; Lymphocyte Activation; | 1987 |