Page last updated: 2024-10-28

hydroxyurea and Carcinoma, Anaplastic

hydroxyurea has been researched along with Carcinoma, Anaplastic in 49 studies

Research Excerpts

ExcerptRelevanceReference
" levofolinic acid and oral hydroxyurea on a weekly schedule is well tolerated by the vast majority of patients with locally advanced and/or metastatic carcinoma of the pancreas or the gallbladder."9.08Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.). ( Colucci, G; Fortunato, S; Gebbia, N; Gebbia, V; Giotta, F; Giuseppe, S; Majello, E; Pezzella, G; Riccardi, F; Testa, A, 1996)
"Long-term follow-up data of a randomized trial that compared hydroxyurea and the hypoxic-cell radiosensitizer to misonidazole as adjuncts to standard radiation therapy in locally advanced carcinoma of the cervix are reported."9.07Hydroxyurea versus misonidazole with radiation in cervical carcinoma: long-term follow-up of a Gynecologic Oncology Group trial. ( Bundy, BN; Creasman, WT; d'Ablaing, G; Fowler, WC; Keys, HM; Mortel, R; Stehman, FB; Thomas, G, 1993)
"Since 1968, hydroxyurea has been used as a radiosensitizer in combination modality treatments for carcinoma of the cervix."8.78Experience with hydroxyurea as a radiosensitizer in carcinoma of the cervix. ( Stehman, FB, 1992)
"The cytotoxicity of 1-beta-D-arabinofuranosylcytosine (ara-C) in combination with hydroxyurea (HU) or 2'-deoxyguanosine (GdR) on human gastric carcinoma MK-1 cells and colon carcinoma HT-15 cells was studied."7.68Synergistic inhibition of human gastric carcinoma cell growth by 1-beta-D-arabinofuranosylcytosine and hydroxyurea or 2'-deoxyguanosine in vitro. ( Kamiguchi, H; Kawahara, T; Matsumoto, M; Ohkubo, T; Tsuda, M; Yamamura, M, 1992)
"An analysis of the risk of progression towards leukemia, carcinoma and myelofibrosis was performed in 93 patients treated by 32P alone (PVSG protocols) since 1970-1979, 395 patients over the age of 65 years treated by 32P with or without maintenance therapy using hydroxyurea (French protocol) since 1980-1994, and 202 patients under the age of 65 treated by either hydroxyurea or pipobroman since 1980."6.18Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias". ( Dresch, C; Echard, M; Goguel, A; Grange, MJ; Lejeune, F; Najean, Y; Rain, JD, 1996)
" levofolinic acid and oral hydroxyurea on a weekly schedule is well tolerated by the vast majority of patients with locally advanced and/or metastatic carcinoma of the pancreas or the gallbladder."5.08Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.). ( Colucci, G; Fortunato, S; Gebbia, N; Gebbia, V; Giotta, F; Giuseppe, S; Majello, E; Pezzella, G; Riccardi, F; Testa, A, 1996)
"Long-term follow-up data of a randomized trial that compared hydroxyurea and the hypoxic-cell radiosensitizer to misonidazole as adjuncts to standard radiation therapy in locally advanced carcinoma of the cervix are reported."5.07Hydroxyurea versus misonidazole with radiation in cervical carcinoma: long-term follow-up of a Gynecologic Oncology Group trial. ( Bundy, BN; Creasman, WT; d'Ablaing, G; Fowler, WC; Keys, HM; Mortel, R; Stehman, FB; Thomas, G, 1993)
"Forty-five evaluable patients with stage IIIB carcinoma of the uterine cervix were entered into a prospective, double-blind, randomized study to evaluate the possible radiation-potentiating properties of hydroxyurea."5.06Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer. ( Emrich, LJ; Piver, MS; Vongtama, V, 1987)
"Since 1968, hydroxyurea has been used as a radiosensitizer in combination modality treatments for carcinoma of the cervix."4.78Experience with hydroxyurea as a radiosensitizer in carcinoma of the cervix. ( Stehman, FB, 1992)
"The cytotoxicity of 1-beta-D-arabinofuranosylcytosine (ara-C) in combination with hydroxyurea (HU) or 2'-deoxyguanosine (GdR) on human gastric carcinoma MK-1 cells and colon carcinoma HT-15 cells was studied."3.68Synergistic inhibition of human gastric carcinoma cell growth by 1-beta-D-arabinofuranosylcytosine and hydroxyurea or 2'-deoxyguanosine in vitro. ( Kamiguchi, H; Kawahara, T; Matsumoto, M; Ohkubo, T; Tsuda, M; Yamamura, M, 1992)
"Treatment of locoregionally advanced nasopharyngeal cancer with induction chemotherapy followed by concomitant chemoradiotherapy resulted in excellent overall survival with acceptable toxicity."2.71Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer. ( Haraf, DJ; Kies, MS; Mittal, BB; Oh, JL; Vokes, EE; Weichselbaum, RR; Witt, ME, 2003)
" Pharmacodynamic studies were performed to assess drug effects on levels of deoxyuridine triphosphate (dUTP) and thymidine triphosphate (TTP) pools in peripheral-blood mononuclear cells (PBMCs) before and 6 hours after treatment using a highly sensitive DNA polymerase assay."2.69Phase II/pharmacodynamic trial of dose-intensive, weekly parenteral hydroxyurea and fluorouracil administered with interferon alfa-2a in patients with refractory malignancies of the gastrointestinal tract. ( Berkenblit, R; Damle, S; Haynes, H; Kaleya, R; Ladner, RD; Murgo, A; Schechner, R; Wadler, S, 1999)
"The majority of patients with head and neck cancer die of locoregional recurrence of disease following surgery and/or radiotherapy."2.67Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer. ( Haraf, DJ; McEvilly, JM; Mick, R; Panje, WR; Vokes, EE; Weichselbaum, RR, 1992)
"Thirty-nine patients with head and neck cancer were entered into Phase I-II study of simultaneous radiation therapy with continuous infusion fluorouracil at 800 mg/m2/day and escalating doses of hydroxyurea."2.67Survival and analysis of failure following hydroxyurea, 5-fluorouracil and concomitant radiation therapy in poor prognosis head and neck cancer. ( Haraf, DJ; Panje, WR; Vokes, EE; Weichselbaum, RR, 1991)
"Previously, we reported that a gastric cancer cell line, SNU-719, that is naturally infected with EBV closely resembles EBVaGC."1.35Maintenance of the viral episome is essential for the cell survival of an Epstein-Barr virus positive gastric carcinoma cell line. ( Kim, M; Lee, SK; Oh, ST, 2009)
"Sixty-six patients with advanced head and neck cancer 57 of whom had failed to respond to prior irradiation, were treated according to two protocols."1.26[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)]. ( Asselin, B; Bataini, JP; Brugère, J; Garcia-Giralt, E; Jaulerry, M; Jouve, M; Palangie, T; Pouillart, P, 1980)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199026 (53.06)18.7374
1990's16 (32.65)18.2507
2000's5 (10.20)29.6817
2010's2 (4.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Song, MJ1
Oh, ST1
Kim, M1
Lee, SK1
Lambertz, N1
Koehler, J1
Schulte, DM1
Kuehl, H1
Wohlschlaeger, J1
Hense, J1
Schuler, M1
Mueller, OM1
Golden, DW1
Rudra, S1
Witt, ME2
Nwizu, T1
Cohen, EE1
Blair, E1
Stenson, KM1
Vokes, EE5
Haraf, DJ4
Wang, L1
Chen, L1
Zhu, L1
Rawle, M1
Nie, S1
Zhang, J1
Ping, Z1
Kangrong, C1
Jacob, TJ1
Oh, JL1
Kies, MS1
Mittal, BB1
Weichselbaum, RR4
BICKERS, JN1
GALE, GR1
Wakisaka, N1
Yoshizaki, T1
Raab-Traub, N1
Pagano, JS1
Pouillart, P1
Palangie, T1
Garcia-Giralt, E1
Jouve, M1
Bataini, JP1
Jaulerry, M1
Brugère, J1
Asselin, B1
Shields, TW1
Higgins, GA1
Humphrey, EW1
Matthews, MJ1
Keehn, RJ1
Kujawska, J1
Krawczyk, K1
Najean, Y2
Rain, JD2
Toubert, ME1
Rose, PG2
Stehman, FB3
Bundy, BN3
Thomas, G1
Keys, HM1
d'Ablaing, G1
Fowler, WC1
Mortel, R1
Creasman, WT1
Sarraf, CE1
Ansari, TW1
Conway, P1
Notay, M1
Hill, S1
Alison, MR1
Haaz, MC1
Fischel, JL1
Formento, P1
Renée, N1
Etienne, MC1
Milano, G1
Gebbia, V1
Majello, E1
Testa, A1
Pezzella, G1
Giuseppe, S1
Giotta, F1
Riccardi, F1
Fortunato, S1
Colucci, G1
Gebbia, N1
Dresch, C1
Goguel, A1
Lejeune, F1
Echard, M1
Grange, MJ1
Kucera, PR1
Deppe, G2
Reddy, S1
O'Connor, DM1
Watkins, EB1
Thigpen, JT1
Maiman, MA1
Clarke-Pearson, DL1
Insalaco, S1
Wadler, S1
Damle, S1
Haynes, H1
Kaleya, R1
Schechner, R1
Berkenblit, R1
Ladner, RD1
Murgo, A1
Vlak, JM1
Rozijn, TH1
Sussenbach, JS3
Mick, R2
McEvilly, JM1
Panje, WR3
Balducci, L1
Hardy, CL1
Matsumoto, M1
Kawahara, T1
Tsuda, M1
Ohkubo, T1
Kamiguchi, H1
Yamamura, M1
Albain, KS1
Swinnen, LJ1
Erickson, LC1
Stiff, PJ1
Fisher, SG1
Fisher, RI1
Schilsky, RL1
Awan, AM1
Moran, WJ1
Goldman, MD1
Tybor, AG1
Piver, M1
Khalil, M1
Emrich, LJ2
Piver, MS1
Vongtama, V1
Seidel, HJ1
Coyle, M2
McMahon, M2
Strauss, B3
Kato, K1
Dolyniuk, M1
Wheeler, GP1
Bowdon, BJ1
Adamson, DJ1
Vail, MH1
Hampar, B1
Derge, JG1
Martos, LM1
Tagamets, MA1
Burroughs, MA1
van der Merwe, AM1
Falkson, G1
Sandison, AG1
van Dyk, JJ1
Falkson, HC1
Ellens, DJ1
Jansz, HS1
Jabara, AG1
Wilson, FC1
Fisher, RJ1
Bello, LJ1
Goldin, A1
Carter, SK1
van der Vliet, PC1
Ariel, IM1
LePar, E1
Faust, DS1
Brady, LW1
Beckloff, GL1
Rajewsky, MF1
Coyle, MB1
Long, DL1
Pierre, RV1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on Adaptive Radiotherapy and Multimodal Information of Cervical Cancer Assisted by Artificial Intelligence[NCT04022018]122 participants (Anticipated)Interventional2019-12-18Recruiting
AVF3963s Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin and Radiotherapy in the Primary Treatment of Cervix Cancer[NCT00600210]Phase 20 participants (Actual)Interventional2008-01-31Withdrawn (stopped due to low patient accrual)
A Prospective Phase II Study of Prophylactic TPO Combined With Bone Marrow-Sparing Intensity-Modulated Radiotherapy to Reduce Platelet Inhibition in Patients With Esophageal Cancer Undergoing Concurrent Chemoradiotherapy[NCT05944809]Phase 227 participants (Anticipated)Interventional2023-07-15Not yet recruiting
A Phase III Randomized Clinical Trial to Study the Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Uterine Cervix.[NCT03256916]Phase 3348 participants (Anticipated)Interventional2018-01-16Recruiting
Phase II Trial To Evaluate The Efficiency And Safety Of Neoadjuvant Chemotherapy In Locally Advanced Cancer Cervix[NCT04789941]Phase 250 participants (Anticipated)Interventional2021-04-01Not yet recruiting
Safety and Efficacy of Gemcitabine Based Neoadjuvant Chemotherapy Followed by Chemoradiation in Locally Advanced Cervical Cancer Patients and Association With Human Equilibrative Nucleoside Transporter 1 (hENT1) Expression[NCT02309658]Phase 250 participants (Actual)Interventional2013-09-30Completed
Randomized Phase III Clinical Trial of Weekly Versus Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer[NCT01561586]Phase 3374 participants (Anticipated)Interventional2012-03-31Recruiting
Radiosensitization With a COX-2 Inhibitor (Celecoxib), With Chemoradiation for Cancer of the Head and Neck[NCT00581971]Phase 1/Phase 230 participants (Actual)Interventional2002-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Response as Evaluated by Recurrence of Diseases

Evaluate the response to concurrent celecoxib, carboplatin, paclitaxel, and radiotherapy in the treatment of locally advanced SSC of the head and neck. Response is determined by local control only, local and distant metastasis, distant metastasis only, second primary, and surgical salvage. (NCT00581971)
Timeframe: 2 years from end of treatment (Radiation therapy)

InterventionParticipants (Number)
Local Control OnlyLocal Control and Distant MetastasisDistant Metastatsis OnlySecondary Primary - Site UnknownSurgical Salvage
Recurrence62123

Toxicity of Celecoxib With Concurrent Weekly Chemotherapy and Radiotherapy in the Treatment of Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck.

Particpants experiencing Acute Toxicities > Grade 3 (NCT00581971)
Timeframe: 2 years from radiation therapy

Interventionparticipants (Number)
HematologicDermatitisMucositis/Dysphagia
Acute Toxicity12716

Reviews

5 reviews available for hydroxyurea and Carcinoma, Anaplastic

ArticleYear
Locally advanced cervical carcinoma: the role of chemoradiation.
    Seminars in oncology, 1994, Volume: 21, Issue:1

    Topics: Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Human

1994
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Experience with hydroxyurea as a radiosensitizer in carcinoma of the cervix.
    Seminars in oncology, 1992, Volume: 19, Issue:3 Suppl 9

    Topics: Animals; Carcinoma; Chemotherapy, Adjuvant; Female; Humans; Hydroxyurea; Radiation-Sensitizing Agent

1992
Rationale of combination chemotherapy based on preclinical experiments.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma; Cytarabine; Drug Synergism; Humans; Hydroxyur

1973
An overview of the status of the nitrosoureas in other tumors.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Carcinoma, Br

1973

Trials

15 trials available for hydroxyurea and Carcinoma, Anaplastic

ArticleYear
Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Ci

2003
Prolonged intermittent adjuvant chemotherapy with CCNU and hydroxyurea after resection of carcinoma of the lung.
    Cancer, 1982, Nov-01, Volume: 50, Issue:9

    Topics: Carcinoma; Clinical Trials as Topic; Humans; Hydroxyurea; Lomustine; Lung Neoplasms; Male; Neoplasm

1982
[Radioisotope teletherapy with or without hydroxyurea in the treatment of inoperable lung cancer].
    Nowotwory, 1981, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Clinical Trials as Topic; Follow-Up Studies; Humans; Hydroxy

1981
[Treatment of polycythemia with 32P with or without hydroxyurea maintenance therapy. Preliminary results in 237 elderly and high vascular risk subjects studied since 1980].
    Presse medicale (Paris, France : 1983), 1993, Dec-11, Volume: 22, Issue:39

    Topics: Age Factors; Aged; Carcinoma; Cardiovascular Diseases; Female; Humans; Hydroxyurea; Injections, Intr

1993
Hydroxyurea versus misonidazole with radiation in cervical carcinoma: long-term follow-up of a Gynecologic Oncology Group trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Cause of Death; Chemotherapy, Adjuvant; Female; Follow-Up

1993
Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Results of a multicenter study of the Southern Italy Oncology Group (G.O.I.M.).
    Cancer, 1996, Sep-15, Volume: 78, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplast

1996
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
Hydroxyurea, 5-fluorouracil infusion, and cisplatin adjunct to radiation therapy in cervical carcinoma: a phase I-II trial of the Gynecologic Oncology Group.
    Gynecologic oncology, 1997, Volume: 66, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcin

1997
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.
    The New England journal of medicine, 1999, Apr-15, Volume: 340, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

1999
Phase II/pharmacodynamic trial of dose-intensive, weekly parenteral hydroxyurea and fluorouracil administered with interferon alfa-2a in patients with refractory malignancies of the gastrointestinal tract.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Deoxyurac

1999
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
    Journal of the National Cancer Institute, 1992, Jun-03, Volume: 84, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisp

1992
Survival and analysis of failure following hydroxyurea, 5-fluorouracil and concomitant radiation therapy in poor prognosis head and neck cancer.
    American journal of clinical oncology, 1991, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carc

1991
Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer.
    Journal of surgical oncology, 1989, Volume: 42, Issue:2

    Topics: Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Fe

1989
Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer.
    Journal of surgical oncology, 1987, Volume: 35, Issue:2

    Topics: Adult; Aged; Carcinoma; Combined Modality Therapy; Female; Humans; Hydroxyurea; Lymphatic Metastasis

1987
Advanced lung cancer: A clinical trial of radiotherapy plus two drug combination regimens.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Nov-24, Volume: 47, Issue:46

    Topics: Adenocarcinoma; Amides; Antineoplastic Agents; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous

1973

Other Studies

30 other studies available for hydroxyurea and Carcinoma, Anaplastic

ArticleYear
Maintenance of the viral genome may be the Achilles' tendon for virus-associated cancer.
    Archives of pharmacal research, 2009, Volume: 32, Issue:5

    Topics: Carcinoma; Cell Proliferation; Cell Survival; Cell Transformation, Viral; Epstein-Barr Virus Nuclear

2009
Maintenance of the viral episome is essential for the cell survival of an Epstein-Barr virus positive gastric carcinoma cell line.
    Archives of pharmacal research, 2009, Volume: 32, Issue:5

    Topics: Blotting, Southern; Carcinoma; Cell Proliferation; Cell Survival; Cell Transformation, Viral; Dose-R

2009
Multivisceral systemic metastases from an intracranial anaplastic meningioma: a case report and review of literature.
    Clinical neurology and neurosurgery, 2011, Volume: 113, Issue:7

    Topics: Aged; Antineoplastic Agents; Biopsy; Brain Neoplasms; Carcinoma; Fatal Outcome; Female; Humans; Hydr

2011
Outcomes of induction chemotherapy followed by concurrent chemoradiation for nasopharyngeal carcinoma.
    Oral oncology, 2013, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinom

2013
Regulatory volume decrease is actively modulated during the cell cycle.
    Journal of cellular physiology, 2002, Volume: 193, Issue:1

    Topics: Adenosine Triphosphate; Carcinoma; Cell Cycle; Cell Size; Chloride Channels; Flow Cytometry; G1 Phas

2002
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: CARCINOMA OF THE LUNG.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Adult; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Drug Therapy; Humans; Hydroxyurea

1964
EFFECT OF HYDROXYUREA ON THE INCORPORATION OF THYMIDINE INTO EHRLICH ASCITES TUMOR CELLS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Hydroxyurea

1964
Ribonucleotide reductase inhibitors enhance cidofovir-induced apoptosis in EBV-positive nasopharyngeal carcinoma xenografts.
    International journal of cancer, 2005, Sep-10, Volume: 116, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Interactions; Enzyme

2005
[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
    Bulletin du cancer, 1980, Volume: 67, Issue:3

    Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck

1980
Bromodeoxyuridine-labelled apoptosis after treatment with antimetabolites in two murine tumours and in small intestinal crypts.
    British journal of cancer, 1993, Volume: 68, Issue:4

    Topics: Animals; Apoptosis; Bromodeoxyuridine; Carcinoma; Cytarabine; Hydroxyurea; Intestine, Small; Male; M

1993
Impact of different fluorouracil biochemical modulators on cellular dihydropyrimidine dehydrogenase.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:1

    Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Ce

1996
Studies on the mechanism of replication of adenovirus DNA. IV. Discontinuous DNA Chain propagation.
    Virology, 1975, Volume: 63, Issue:1

    Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Zonal; DNA Replication; Hydroxyurea; Mouth Neopl

1975
High proliferation of early hemopoietic progenitors in tumor-bearing mice.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1992, Volume: 60, Issue:2

    Topics: Anemia; Animals; Bone Marrow; Carcinoma; Cell Division; Hematopoiesis; Hematopoietic Cell Growth Fac

1992
Synergistic inhibition of human gastric carcinoma cell growth by 1-beta-D-arabinofuranosylcytosine and hydroxyurea or 2'-deoxyguanosine in vitro.
    Cancer letters, 1992, Apr-30, Volume: 63, Issue:3

    Topics: Carcinoma; Cell Death; Cell Division; Colonic Neoplasms; Cytarabine; Deoxyguanosine; Deoxyribonucleo

1992
Cytotoxic synergy of cisplatin with concurrent hydroxyurea and cytarabine: summary of an in vitro model and initial clinical pilot experience.
    Seminars in oncology, 1992, Volume: 19, Issue:3 Suppl 9

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Survival; Cisp

1992
Hydroxyurea, fluorouracil, and concomitant radiotherapy in poor-prognosis head and neck cancer: a phase I-II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcino

1989
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic

1970
Failure of alkylated HEp.2 cells to replicate newly synthesized DNA.
    Mutation research, 1971, Volume: 12, Issue:4

    Topics: Alkanes; Alkylating Agents; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient;

1971
DNA synthesis, repair and chromosome breaks in eucaryotic cells.
    The Johns Hopkins medical journal, 1972, Volume: 1

    Topics: Alkylating Agents; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chroma

1972
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
    Cancer research, 1972, Volume: 32, Issue:12

    Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Rep

1972
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:9

    Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line;

1972
Studies on the mechanism of replication of adenovirus DNA. III. Electron microscopy of replicating DNA.
    Virology, 1974, Volume: 61, Issue:2

    Topics: Adenoviridae; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Deoxycytidi

1974
Effect of early inhibition of DNA synthesis by hydroxyurea on 7,12-dimethylbenz(a)anthracene mammary carcinogenesis in the rat.
    The Journal of pathology, 1974, Volume: 113, Issue:4

    Topics: Adenoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma; Depression, Chemical; DNA; Epithel

1974
Regulation of thymidine kinase synthesis in human cells.
    Experimental cell research, 1974, Volume: 89, Issue:2

    Topics: Carbon Radioisotopes; Carcinoma; Cell Division; Cell Line; Cell-Free System; Cycloheximide; Dactinom

1974
Studies on the mechanism of replication of adenovirus DNA. I. The effect of hydroxyurea.
    Virology, 1973, Volume: 54, Issue:1

    Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chromatography; DNA Replicatio

1973
Anticancer therapy with hydrea: comparative study of daily vs. intermittent oral dosage.
    Journal of surgical oncology, 1974, Volume: 6, Issue:1

    Topics: Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Dr

1974
Clinical evaluation of the adjunctive use of hydroxyurea (NSC-32065) in radiation therapy of carcinoma of the lung. A comparative study.
    Radiologia clinica et biologica, 1967, Volume: 36, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Hydroxyurea

1967
Synchronisation in vivo: kinetics of a malignant cell system following temporary inhibition of DNA synthesis with hydroxyurea.
    Experimental cell research, 1970, Volume: 60, Issue:2

    Topics: Animals; Autoradiography; Carcinoma; Culture Techniques; DNA, Neoplasm; Hydroxyurea; Kinetics; Mamma

1970
Cell killing and the accumulation of breaks in the DNA of HEp-2 cells incubated in the presence of hydroxyurea.
    Cancer research, 1970, Volume: 30, Issue:9

    Topics: Antimetabolites; Carcinoma; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cyclohe

1970
Autosomal monosomy mosaicism in human bone marrow aspirate. Report of a case.
    American journal of clinical pathology, 1968, Volume: 50, Issue:4

    Topics: Aged; Aneuploidy; Bone Marrow; Bone Marrow Cells; Carcinoma; Chromosome Aberrations; Chromosome Diso

1968