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hydroxyurea and Carcinogenesis

hydroxyurea has been researched along with Carcinogenesis in 5 studies

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
"This study showed that skin carcinogenesis did not occur in our series of SCD patients exposed to transforming events such as long term HU treatment or prolonged leg ulcers."1.56Sickle cell disease induces resistance to cutaneous carcinogenesis. ( Aractingi, S; Habibi, A; Lionnet, F; Senet, P; Soutou, B, 2020)
"Hydroxyurea (HU) has been widely used in sickle cell disease."1.51Occurrence of acute myeloid leukemia in hydroxyurea-treated sickle cell disease patient. ( El-Deiry, WS; Finnberg, NK; Pu, JJ; Regan, S; Yang, X, 2019)
"In this study, using HNSCC cell lines, we examined the anti-cancer effects and the mechanisms of action of docosahexaenoyl ethanolamide (DHEA) and N-arachidonoyl-L-alanine (NALA), which are polyunsaturated fatty acid (PUFA)-based ethanolamides like AEA."1.435-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells. ( Hah, JH; Jeong, WJ; Oh, SM; Park, SW; Sung, MW, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Regan, S1
Yang, X1
Finnberg, NK1
El-Deiry, WS1
Pu, JJ1
Soutou, B1
Senet, P1
Lionnet, F1
Habibi, A1
Aractingi, S1
Suchánková, T1
Ovesná, P1
Samadder, P1
Souček, K1
Stuckey, R1
García-Rodríguez, N1
Aguilera, A1
Wellinger, RE1
Park, SW1
Hah, JH1
Oh, SM1
Jeong, WJ1
Sung, MW1

Other Studies

5 other studies available for hydroxyurea and Carcinogenesis

ArticleYear
Occurrence of acute myeloid leukemia in hydroxyurea-treated sickle cell disease patient.
    Cancer biology & therapy, 2019, Volume: 20, Issue:11

    Topics: Adult; Anemia, Sickle Cell; Carcinogenesis; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromo

2019
Sickle cell disease induces resistance to cutaneous carcinogenesis.
    Orphanet journal of rare diseases, 2020, 03-06, Volume: 15, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Carcinogenesis; Cross-Sectional Studies; Humans; Hydroxyurea; Leg Ulcer;

2020
Utilization of an automated pipetting system in the cell line-based screening of the activity of a DNA-damaging anti-tumour drug.
    Folia biologica, 2014, Volume: 60 Suppl 1

    Topics: Antineoplastic Agents; Automation; Carcinogenesis; Cell Culture Techniques; Cell Line, Tumor; DNA Da

2014
Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, May-05, Volume: 112, Issue:18

    Topics: Bacterial Proteins; Camptothecin; Carcinogenesis; Cell Cycle; Cell Separation; Chromosomes; DNA; DNA

2015
5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells.
    BMC cancer, 2016, 07-13, Volume: 16

    Topics: Alanine; Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Azoles; B

2016