hydroxyurea has been researched along with Canine Diseases in 20 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The direct cytotoxicity of piroxicam indomethacin, and aspirin against 4 canine tumor cell lines (transitional cell carcinoma, squamous cell carcinoma, melanoma, and soft tissue sarcoma) was determined in short-term growth rate assays and in clonogenic assays." | 3.69 | Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. ( Chan, TC; Knapp, DW; Kuczek, T; Park, B; Reagan, WJ, 1995) |
| "Zileuton was well tolerated and no adverse clinical signs were noted." | 2.70 | Double-blinded, placebo-controlled, cross-over pilot study on the efficacy of zileuton for canine atopic dermatitis. ( Crow, DW; Marsella, R; Nicklin, CF, 2001) |
| "Treatment with hydroxyurea at a dosage of 18 mg/kg twice daily was not effective in controlling the high count of white blood cells." | 1.48 | Hydroxyurea-induced onychomadesis in a dog with chronic myeloid leukemia: A case report. ( Anjos, DSD; Calazans, SG; Costa, PB; Fonseca-Alves, CE; Magalhães, LF; Sierra, OR, 2018) |
| "Hydroxyurea is a cytotoxic chemotherapeutic agent used in a variety of conditions in human and veterinary medicine, and megaloblastic changes associated with its use have been described in multiple species." | 1.46 | Macrocytosis secondary to hydroxyurea therapy. ( Conrado, FO; Leissinger, MK; Speas, AL; Weeden, AL, 2017) |
| " We observed that long-term maintenance with hydroxyurea at a dosage of 15 mg/kg every 48 hours was adequate for managing polycythemia vera, with a survival time of 18 months in the present case." | 1.42 | Diagnosis and Treatment of Primary Erythrocytosis in a Dog: A Case Report. ( Arias, MV; Bonelli, Mde A; Camassa, JA; Diogo, CC; Fabretti, AK; Pereira, PM, 2015) |
| "Hydroxyurea is a chemotherapeutic agent used to treat hypereosinophilic syndrome, mast cell tumours and many myeloproliferative disorders." | 1.34 | Unusual dermatological toxicity of hydroxyurea in two dogs with spontaneously occurring tumours. ( Bonfanti, U; Fileccia, I; Marconato, L, 2007) |
| " Because of insufficient response to treatment after 3 weeks, the dosage of hydroxyurea was increased in both dogs to 2000 mg/m2 p." | 1.32 | Essential thrombocythaemia in two dogs. ( Favier, RP; Teske, E; van Leeuwen, M, 2004) |
| "Hypereosinophilic syndrome was diagnosed." | 1.31 | Successful treatment of hypereosinophilic syndrome in a dog. ( Perkins, M; Watson, A, 2001) |
| "Treatment with hydroxyurea returned the WBC count to reference range within 2 months." | 1.30 | Chronic granulocytic leukemia in a dog. ( Fine, DM; Tvedten, HW, 1999) |
| "Chronic myelogenous leukemia was diagnosed in 7 dogs." | 1.27 | Chronic myelogenous leukemia in the dog. ( Leifer, CE; MacEwen, EG; Matus, RE; Patnaik, AK, 1983) |
| "Severe polycythemia was found in 3 dogs with PCV 68% to 70%." | 1.26 | Diagnosis of canine primary polycythemia and management with hydroxyurea. ( Peterson, ME; Randolph, JF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conrado, FO | 1 |
| Weeden, AL | 1 |
| Speas, AL | 1 |
| Leissinger, MK | 1 |
| Anjos, DSD | 1 |
| Costa, PB | 1 |
| Magalhães, LF | 1 |
| Sierra, OR | 1 |
| Calazans, SG | 1 |
| Fonseca-Alves, CE | 1 |
| Jung, HW | 1 |
| Lee, HC | 1 |
| Kim, JH | 1 |
| Jang, HM | 1 |
| Moon, JH | 1 |
| Sur, JH | 1 |
| Ha, J | 1 |
| Jung, DI | 1 |
| Diogo, CC | 1 |
| Fabretti, AK | 1 |
| Camassa, JA | 1 |
| Bonelli, Mde A | 1 |
| Arias, MV | 1 |
| Pereira, PM | 1 |
| Rassnick, KM | 1 |
| Al-Sarraf, R | 1 |
| Bailey, DB | 1 |
| Chretin, JD | 1 |
| Phillips, B | 1 |
| Zwhalen, CH | 1 |
| Favier, RP | 1 |
| van Leeuwen, M | 1 |
| Teske, E | 2 |
| Marconato, L | 1 |
| Bonfanti, U | 1 |
| Fileccia, I | 1 |
| Wray, JD | 1 |
| Tamura, S | 1 |
| Tamura, Y | 1 |
| Ohoka, A | 1 |
| Hasegawa, T | 1 |
| Uchida, K | 1 |
| Bates, N | 1 |
| Leifer, CE | 1 |
| Matus, RE | 1 |
| Patnaik, AK | 1 |
| MacEwen, EG | 2 |
| Peterson, ME | 1 |
| Randolph, JF | 1 |
| Knapp, DW | 1 |
| Chan, TC | 1 |
| Kuczek, T | 1 |
| Reagan, WJ | 1 |
| Park, B | 1 |
| Gerritsen, RJ | 1 |
| Kraus, JS | 1 |
| Rutteman, GR | 1 |
| Fine, DM | 1 |
| Tvedten, HW | 1 |
| Crow, DW | 1 |
| Marsella, R | 1 |
| Nicklin, CF | 1 |
| Perkins, M | 1 |
| Watson, A | 1 |
| Drazner, FH | 1 |
| McClelland, AJ | 1 |
| Wilkins, RJ | 1 |
| Page, RL | 1 |
| Stiff, ME | 1 |
| McEntee, MC | 1 |
| Walter, LG | 1 |
| Degen, MA | 1 |
| Feldman, BF | 1 |
| Turrel, JM | 1 |
| Goding, B | 1 |
| Kitchell, B | 1 |
| Mandell, CP | 1 |
2 trials available for hydroxyurea and Canine Diseases
| Article | Year |
|---|---|
Phase II open-label study of single-agent hydroxyurea for treatment of mast cell tumours in dogs.
Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Drug Administration Schedule; Female; Hydroxyure | 2010 |
Double-blinded, placebo-controlled, cross-over pilot study on the efficacy of zileuton for canine atopic dermatitis.
Topics: Administration, Oral; Animals; Cross-Over Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Double-Bl | 2001 |
18 other studies available for hydroxyurea and Canine Diseases
| Article | Year |
|---|---|
Macrocytosis secondary to hydroxyurea therapy.
Topics: Anemia, Macrocytic; Animals; Dog Diseases; Dogs; Hematocrit; Hydroxyurea; Male; Mastocytosis, Cutane | 2017 |
Hydroxyurea-induced onychomadesis in a dog with chronic myeloid leukemia: A case report.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Diagnosis, Differential; Disease-Free Survival; Do | 2018 |
Imatinib mesylate plus hydroxyurea chemotherapy for cerebellar meningioma in a Belgian Malinois dog.
Topics: Animals; Benzamides; Cerebellar Neoplasms; Dog Diseases; Dogs; Fatal Outcome; Hydroxyurea; Imatinib | 2014 |
Diagnosis and Treatment of Primary Erythrocytosis in a Dog: A Case Report.
Topics: Animals; Antineoplastic Agents; Diagnosis, Differential; Dog Diseases; Dogs; Euthanasia, Animal; Fat | 2015 |
Essential thrombocythaemia in two dogs.
Topics: Animals; Antisickling Agents; Bone Marrow Cells; Dog Diseases; Dogs; Dose-Response Relationship, Dru | 2004 |
Unusual dermatological toxicity of hydroxyurea in two dogs with spontaneously occurring tumours.
Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Foot Diseases; Hoof and Claw; Hydroxyure | 2007 |
Methaemoglobinaemia caused by hydroxycarbamide (hydroxyurea) ingestion in a dog.
Topics: Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Granulocyte Colony-Stimulating Factor; Hemat | 2008 |
A canine case of skull base meningioma treated with hydroxyurea.
Topics: Animals; Antineoplastic Agents; Brain; Dog Diseases; Dogs; Female; Hydroxyurea; Meningioma; Skull Ba | 2007 |
Hydroxycarbamide (hydroxyurea) toxicity in dogs.
Topics: Animals; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyurea; Hypox | 2008 |
Chronic myelogenous leukemia in the dog.
Topics: Animals; Biopsy, Needle; Blood Cell Count; Bone Marrow; Cytodiagnosis; Dog Diseases; Dogs; Drug Ther | 1983 |
Diagnosis of canine primary polycythemia and management with hydroxyurea.
Topics: Animals; Dog Diseases; Dogs; Female; Hydroxyurea; Male; Polycythemia | 1982 |
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamou | 1995 |
Multi-agent chemotherapy for mast cell tumours in the dog.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dog Diseases; Dogs; Doxor | 1998 |
Chronic granulocytic leukemia in a dog.
Topics: Alopecia; Animals; Antineoplastic Agents; Biopsy; Bone Marrow; Dog Diseases; Dogs; Female; Hydroxyur | 1999 |
Successful treatment of hypereosinophilic syndrome in a dog.
Topics: Animals; Anti-Inflammatory Agents; Dog Diseases; Dogs; Enzyme Inhibitors; Eosinophilia; Female; Hydr | 2001 |
Treatment of basophilic leukemia in a dog.
Topics: Animals; Basophils; Bone Marrow; Bone Marrow Cells; Busulfan; Dog Diseases; Dogs; Erythrocyte Count; | 1975 |
Transient glomerulonephropathy associated with primary erythrocytosis in a dog.
Topics: Animals; Bloodletting; Combined Modality Therapy; Dog Diseases; Dogs; Doxorubicin; Female; Hydroxyur | 1990 |
Thrombocytosis associated with a myeloproliferative disorder in a dog.
Topics: Animals; Blood Platelets; Combined Modality Therapy; Dog Diseases; Dogs; Hydroxyurea; Male; Microsco | 1989 |