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hydroxyurea and Cancer of the Uterus

hydroxyurea has been researched along with Cancer of the Uterus in 17 studies

Research Excerpts

ExcerptRelevanceReference
"Treatment of choriocarcinoma cells (JAr line) for 24 hr with methotrexate, fluorodeoxyuridine, 1-beta-D-arabinofuranosylcytosine, or hydroxyurea, in doses that inhibit DNA synthesis, results in a 2."3.66Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis. ( Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K, 1979)
"Oral hydroxyurea (HU) is a potent radiation sensitizer, but in vitro studies have suggested that prolonged exposure to HU by way of continuous parenteral infusion would enhance clinical efficacy."2.70Phase I clinical trial of parenteral hydroxyurea in combination with pelvic and para-aortic external radiation and brachytherapy for patients with advanced squamous cell cancer of the uterine cervix. ( Anderson, P; Beitler, JJ; Fields, A; Goldberg, G; Haynes, H; Runowicz, CD; Sood, B; Vikram, B; Wadler, S, 2002)
"Significant blood eosinophilia is uncommon in leiomyomas and should raise suspicion of malignant etiology for a pelvic mass."1.37Metastatic uterine leiomyosarcoma and eosinophilia. ( Cheung, WY; Ksienski, D, 2011)
"Surgery combined with chemotherapy was applied in 34 out of 178 patients (19."1.29Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD). ( Kietlińska, Z; Sablińska, B; Zieliński, J, 1993)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertolini, F1
Cassisa, A1
Miggiano, MC1
Gasparin, P1
Ksienski, D1
Cheung, WY1
HOWE, CD1
SAMUELS, ML1
Bagshawe, KD3
Weed, JC1
Barnard, DE1
Currie, JL2
Clayton, LA1
Hammond, CB2
Sablińska, B1
Kietlińska, Z1
Zieliński, J1
Currie, J1
Blessing, JA3
Muss, HB1
Fowler, J1
Berman, M2
Burke, TW1
McGehee, R1
Soper, JT2
Beitler, JJ1
Anderson, P1
Haynes, H1
Sood, B1
Fields, A1
Goldberg, G1
Vikram, B1
Runowicz, CD1
Wadler, S1
Azizkhan, JC1
Speeg, KV1
Stromberg, K1
Goode, D1
Surwit, EA1
Suciu, TN1
Schmidt, HJ1
Brady, LW1
Sharma, K1
Southall, PJ1
Boden, JA1
Boxer, GM2
Patridge, TA1
Antoniw, P1
Pedley, RB1
Curry, SL1
DiSaia, PJ1
Twiggs, LB1
Bolis, G1
Bonazzi, C1
Landoni, F1
Mangili, G1
Vergadoro, F1
Zanaboni, F1
Mangioni, C1
Wong, LC1
Choo, YC1
Ma, HK1
Boden, J1
Britton, DW1
Green, A1
Partridge, T1
Pedley, B1
Sharma, S1
Southall, P1

Reviews

2 reviews available for hydroxyurea and Cancer of the Uterus

ArticleYear
Treatment of high-risk choriocarcinoma.
    The Journal of reproductive medicine, 1984, Volume: 29, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Cycl

1984
Combined modality therapy of gynecologic cancer.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Evaluation Studies as Topic; Female; Genit

1975

Trials

4 trials available for hydroxyurea and Cancer of the Uterus

ArticleYear
Combination chemotherapy with hydroxyurea, dacarbazine (DTIC), and etoposide in the treatment of uterine leiomyosarcoma: a Gynecologic Oncology Group study.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Etoposide; Female; Humans;

1996
Phase II trial of hydroxyurea, dacarbazine (DTIC), and etoposide (VP-16) in mixed mesodermal tumors of the uterus: a Gynecologic Oncology Group study.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease Progression; Etopo

1996
Phase I clinical trial of parenteral hydroxyurea in combination with pelvic and para-aortic external radiation and brachytherapy for patients with advanced squamous cell cancer of the uterine cervix.
    International journal of radiation oncology, biology, physics, 2002, Mar-01, Volume: 52, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy;

2002
A prospective randomized comparison of methotrexate, dactinomycin, and chlorambucil versus methotrexate, dactinomycin, cyclophosphamide, doxorubicin, melphalan, hydroxyurea, and vincristine in "poor prognosis" metastatic gestational trophoblastic disease:
    Obstetrics and gynecology, 1989, Volume: 73, Issue:3 Pt 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin;

1989

Other Studies

11 other studies available for hydroxyurea and Cancer of the Uterus

ArticleYear
Skin nodules in onset of acute myeloid leukemia, a myelomonocytic variant case.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2017, Volume: 152, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cytarabine; Daunorubicin; Delayed Diagnosis;

2017
Metastatic uterine leiomyosarcoma and eosinophilia.
    Obstetrics and gynecology, 2011, Volume: 117, Issue:2 Pt 2

    Topics: Antineoplastic Agents; Benzamides; Dyspnea; Eosinophilia; Fatal Outcome; Female; Humans; Hydroxyurea

2011
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: UROLOGIC AND GYNECOLOGIC NEOPLASMS.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Adenocarcinoma; Anemia; Anemia, Aplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Ther

1964
Chemotherapy with the modified Bagshawe protocol for poor prognosis metastatic trophoblastic disease.
    Obstetrics and gynecology, 1982, Volume: 59, Issue:3

    Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Dr

1982
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
    European journal of gynaecological oncology, 1993, Volume: 14 Suppl

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Chorioca

1993
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-R

1979
A new combination chemotherapy for resistant trophoblastic disease.
    Gynecologic oncology, 1979, Volume: 8, Issue:1

    Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Resistance; Drug Therapy, Combina

1979
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resi

1991
EMA/CO regimen in high-risk gestational trophoblastic tumor (GTT).
    Gynecologic oncology, 1988, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin;

1988
Modified Bagshawe's regimen in high-risk gestational trophoblastic disease.
    Gynecologic oncology, 1986, Volume: 23, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide;

1986
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.
    British journal of cancer, 1987, Volume: 55, Issue:3

    Topics: Animals; Choriocarcinoma; Colon; DNA; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Methot

1987