Page last updated: 2024-10-28

hydroxyurea and Cancer of Mouth

hydroxyurea has been researched along with Cancer of Mouth in 30 studies

Research Excerpts

ExcerptRelevanceReference
"A consecutive sample of 29 patients with advanced oropharyngeal or hypopharyngeal cancer who were treated with intravenous hydroxyurea and concomitant hyperfractionated, accelerated radiotherapy."5.11Decreased short- and long-term swallowing problems with altered radiotherapy dosing used in an organ-sparing protocol for advanced pharyngeal carcinoma. ( Beitler, JJ; Goldman, SY; Smith, RV; Wadler, SS, 2004)
"Oral squamous cell carcinomas induced in rats by 4-nitroquinoline-1-oxide (NQO) show substantial overexpression of cyclooxygenase-2 (COX-2) when compared with adjacent phenotypically normal oral tissues."1.36Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors. ( Horn, TL; Johnson, WD; Lubet, RA; McCormick, DL; Phillips, JM; Steele, VE, 2010)
"Hydroxyurea was stopped at this time, and the patient underwent treatment with pipobroman."1.31[Multiple skin and mouth squamous cell carcinomas related to long-term treatment with hydroxyurea]. ( Estève, E; Georgescu, V; Heitzmann, P; Martin, L, 2001)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199021 (70.00)18.7374
1990's1 (3.33)18.2507
2000's4 (13.33)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, AN1
Jiang, SS1
Fan, CC1
Lo, YK1
Kuo, CY1
Chen, CH1
Liu, YL1
Lee, CC1
Chen, WS1
Huang, TS1
Wang, TY1
Lee, AY1
McCormick, DL1
Phillips, JM1
Horn, TL1
Johnson, WD1
Steele, VE1
Lubet, RA1
Pederson, AW1
Salama, JK1
Witt, ME1
Stenson, KM1
Blair, EA1
Vokes, EE1
Haraf, DJ1
Budrukkar, A1
Muttagi, S1
Shahid, T1
Chatturvedi, P1
Banavali, S1
Laskar, SG1
Murthy, V1
D'Cruz, A1
Agarwal, JP1
Shirlaw, PJ1
Chikte, U1
MacPhail, L1
Schmidt-Westhausen, A1
Croser, D1
Reichart, P1
Smith, RV1
Goldman, SY1
Beitler, JJ1
Wadler, SS1
Li, N1
Sood, S1
Wang, S1
Fang, M1
Wang, P1
Sun, Z1
Yang, CS1
Chen, X1
Lerner, HJ3
Beckloff, GL2
Estève, E1
Georgescu, V1
Heitzmann, P1
Martin, L1
Price, LA1
Hill, BT1
Calvert, AH1
Shaw, HJ1
Hughes, KB1
Goldsmith, MA1
Carter, SK1
Bitter, K1
Bitter, BS1
Perlin, E1
Vlak, JM1
Rozijn, TH1
Sussenbach, JS3
Fountzilas, G1
Daniilidis, J1
Kosmidis, P1
Sridhar, KS1
Kalogera-Fountzila, A1
Banis, K1
Avramidis, V1
Tsavdaridis, D1
Themelis, C1
Zaramboukas, T1
Noble, TA1
Carr, DS1
Gonzalez, MF1
Oberfield, RA1
Bertino, JR1
Mosher, MB1
DeConti, RC1
Marchetta, FC1
Stephens, FO1
Ellens, DJ1
Jansz, HS1
Bello, LJ1
Patel, D1
van der Vliet, PC1
Richards, GJ1
Chambers, RG1
Lipshutz, H2
Stefani, S1
Eells, RW1
Abbate, J1
Lerner, H1
Sheiman, RA1
Wayne, KS1
Godwin, MC1

Reviews

3 reviews available for hydroxyurea and Cancer of Mouth

ArticleYear
Oral and dental care and treatment protocols for the management of HIV-infected patients.
    Oral diseases, 2002, Volume: 8 Suppl 2

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotic Prophylaxis; Antiretroviral Thera

2002
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
    Cancer treatment reviews, 1975, Volume: 2, Issue:2

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluoro

1975
Use of a trypsin, Peru balsam, and castor oil spray on the oral mucosa: case report and review of the literature.
    Pharmacotherapy, 1989, Volume: 9, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Balsams; Carcinoma, Squamous Cell; Castor Oil

1989

Trials

2 trials available for hydroxyurea and Cancer of Mouth

ArticleYear
Decreased short- and long-term swallowing problems with altered radiotherapy dosing used in an organ-sparing protocol for advanced pharyngeal carcinoma.
    Archives of otolaryngology--head & neck surgery, 2004, Volume: 130, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Deglutition Disorders; Dose Fractiona

2004
Hydroxyurea and radiotherapy in head and neck cancer. Results of a prospective controlled study in 126 patients.
    Radiology, 1971, Volume: 101, Issue:2

    Topics: Adult; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle

1971

Other Studies

25 other studies available for hydroxyurea and Cancer of Mouth

ArticleYear
Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents.
    Cancer letters, 2013, Sep-01, Volume: 337, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Camptothecin; Carcinoma, Squamous Cell; Cell Cy

2013
Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Gene Expr

2010
Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer.
    American journal of clinical oncology, 2011, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc

2011
Second primary head and neck squamous cell cancers with aggressive behavior in patients with chronic myeloid leukaemia.
    The British journal of oral & maxillofacial surgery, 2012, Volume: 50, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Carcinoma, Squamous Cell; Cause of Death; Disease-Fr

2012
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Mar-01, Volume: 11, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carcinogen

2005
Combined chemotherapy and radiotherapy. Preliminary results of clinical trial of hydroxyurea and x-irradiation in the treatment of epidermoid cancers of the head and neck.
    The American surgeon, 1967, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Humans; Hydroxyurea; Male; Middle Ag

1967
[Multiple skin and mouth squamous cell carcinomas related to long-term treatment with hydroxyurea].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:8-9

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Humans; Hydroxyurea; Mouth Neoplasms; Neo

2001
Kinetically-based multiple drug treatment for advanced head and neck cancer.
    British medical journal, 1975, Jul-05, Volume: 3, Issue:5974

    Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neopla

1975
[The cell-cycle phase-specific effect of bleomycin on squamous-cell carcinomas following synchronization with hydroxyurea].
    Fortschritte der Kiefer- und Gesichts-Chirurgie, 1976, Volume: 21

    Topics: Bleomycin; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cytological Techniques; Dose-Resp

1976
Chemotherapy for oral malignant disease.
    Otolaryngologic clinics of North America, 1979, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Inje

1979
Studies on the mechanism of replication of adenovirus DNA. IV. Discontinuous DNA Chain propagation.
    Virology, 1975, Volume: 63, Issue:1

    Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Zonal; DNA Replication; Hydroxyurea; Mouth Neopl

1975
Platinum-based induction chemotherapy followed by radiation as definitive treatment for patients with locally advanced cancer of the oral cavity, oropharynx and hypopharynx. A retrospective analysis of 32 cases.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell;

1991
The role of chemotherapy in the treatment of carcinoma of the oral cavity.
    Otolaryngologic clinics of North America, 1972, Volume: 5, Issue:2

    Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous

1972
Chemotherapy of cancer of the head and neck.
    Cancer, 1973, Volume: 31, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheteriza

1973
Proceedings: Carcinoma of the oral cavity--general principles of therapy.
    Journal of surgical oncology, 1974, Volume: 6, Issue:4

    Topics: Azirines; Bleomycin; Carcinoma, Squamous Cell; Cryosurgery; Dactinomycin; Doxorubicin; Head and Neck

1974
Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours.
    The Australian and New Zealand journal of surgery, 1974, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cystadenocarcinoma; Drug Th

1974
Studies on the mechanism of replication of adenovirus DNA. III. Electron microscopy of replicating DNA.
    Virology, 1974, Volume: 61, Issue:2

    Topics: Adenoviridae; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Deoxycytidi

1974
Regulation of thymidine kinase synthesis in human cells.
    Experimental cell research, 1974, Volume: 89, Issue:2

    Topics: Carbon Radioisotopes; Carcinoma; Cell Division; Cell Line; Cell-Free System; Cycloheximide; Dactinom

1974
Hydroxyurea its value in 50 cases of advanced cancers.
    Indian journal of cancer, 1973, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Humans; Hydroxyurea; Leukemia, Myeloid; Lymphoma; Male; Middle Aged; Mouth Neopla

1973
Studies on the mechanism of replication of adenovirus DNA. I. The effect of hydroxyurea.
    Virology, 1973, Volume: 54, Issue:1

    Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chromatography; DNA Replicatio

1973
Hydroxyurea in the treatment of neoplasms of the head and neck. A resurvey.
    American journal of surgery, 1973, Volume: 126, Issue:4

    Topics: Administration, Oral; Ear Neoplasms; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea

1973
Six year survival in the combined treatment of far advanced head and neck cancer under a combined therapy program.
    American journal of surgery, 1973, Volume: 126, Issue:4

    Topics: Carcinoma, Squamous Cell; Evaluation Studies as Topic; Head and Neck Neoplasms; Humans; Hydroxyurea;

1973
Three-year observation of combined treatment for far advanced cancer of the head and neck.
    American journal of surgery, 1969, Volume: 118, Issue:5

    Topics: Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Mouth Neoplasms

1969
Oral carcinoma and hypercalcemia.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1970, Volume: 92, Issue:2

    Topics: Adult; Autopsy; Blood Chemical Analysis; Carcinoma, Squamous Cell; Cobalt Isotopes; Humans; Hydrocor

1970
Concomitant hydroxyurea and radiotherapy in the management of 60 patients with head and neck cancer.
    The American surgeon, 1969, Volume: 35, Issue:7

    Topics: Adult; Aged; Female; Gingival Diseases; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Maxillar

1969