hydroxyurea has been researched along with Brain Edema in 2 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral treatment of zileuton at 10 or 50 mg/kg significantly reduced cerebral water content and infarct volume." | 1.35 | 5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9. ( Chen, CM; Shi, SS; Tu, XK; Wang, CH; Yang, WZ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Sherchan, P | 1 |
| Huang, L | 1 |
| Akyol, O | 1 |
| McBride, DW | 1 |
| Zhang, JH | 1 |
| Tu, XK | 1 |
| Yang, WZ | 1 |
| Shi, SS | 1 |
| Chen, CM | 1 |
| Wang, CH | 1 |
2 other studies available for hydroxyurea and Brain Edema
| Article | Year |
|---|---|
Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5-LOX/LTB4 Cascade Activation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Biomarkers; Brain; Brain Edema; Brain Injuries; Elapid Venoms; | 2017 |
5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9.
Topics: Animals; Arachidonate 5-Lipoxygenase; Body Water; Brain; Brain Edema; Brain Ischemia; Dose-Response | 2009 |