hydroxyurea has been researched along with Bone Loss, Osteoclastic in 16 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyurea treatment, as well as and long- and short-acting narcotics were given, with little improvement in symptoms." | 1.33 | Primary hyperparathyroidism mimicking vaso-occlusive crises in sickle cell disease. ( Abish, S; Albuquerque, P; Alyaarubi, S; Gale, M; Jabado, N; Krishnamoorthy, P, 2006) |
| "In mouse calvariae, the effect on bone resorption of the thyroid hormones is dependent on increased cellular replication, perhaps of osteoclast precursors, or other bone cells involved in the resorptive process." | 1.30 | Prostaglandin-independent stimulation of bone resorption in mouse calvariae and in isolated rat osteoclasts by thyroid hormones (T4, and T3). ( Conaway, HH; Lerner, UH; Ransjö, M, 1998) |
| "This increase in bone resorption was additive to the resorptive effect resulting from the addition of 10(-9)-10(-7) M parathyroid hormone (PTH), but was not additive to similar effects produced by the addition of 10(-9)-10(-7) M prostaglandin E2 (PGE2)." | 1.30 | In vitro bone resorption is dependent on physiological concentrations of zinc. ( Chen, D; Pierce, WM; Waite, LC, 1998) |
| "When hydroxyurea was added to the culture in order to suppress the proliferation and the subsequent differentiation of osteoblastic cells on rough surfaces, the increase in resorption on the rough surfaces was effaced; however, this agent had little affect on resorption of the smooth surfaces." | 1.30 | Disaggregated osteoclasts increase in resorption activity in response to roughness of bone surface. ( Hatano, K; Inoue, H; Kojo, T; Matsunaga, T; Tsujisawa, T; Uchida, Y; Uchiyama, C, 1999) |
| "In vitro stimulation of bone resorption was observed with the glucocorticoids hydrocortisone and dexamethasone." | 1.29 | Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone. ( Conaway, HH; Grigorie, D; Lerner, UH, 1996) |
| "1,25(OH)2D3 potently stimulated bone resorption after 3 and 6 days of culture in fetal mouse long bones and calvaria." | 1.28 | Evidence for the functional involvement of protein kinase C in the action of 1,25-dihydroxyvitamin D3 in bone. ( Birkenhäger, JC; Bos, MP; Buurman, CJ; Pols, HA; Staal, A; van den Bemd, GJ; van Leeuwen, JP, 1992) |
| "Bone resorption was assessed by the release of 45Ca from prelabeled mouse calvarial bone fragments." | 1.28 | On the role of cyclic AMP as a mediator of bone resorption: gamma-interferon completely inhibits cholera toxin- and forskolin-induced but only partially inhibits parathyroid hormone-stimulated 45Ca release from mouse calvarial bones. ( Hoffmann, O; Klaushofer, K; Lerner, UH; Ljunggren, O; Peterlik, M; Ransjö, M, 1991) |
| "With bFGF, increased bone resorption was observed at 10(-9) M but not at 10(-8) M." | 1.28 | Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones. ( Raisz, LG; Simmons, HA, 1991) |
| "We have shown that LIF stimulates bone resorption and DNA synthesis in bone organ culture and, in vivo, LIF has been shown to have marked effects on bone remodeling." | 1.28 | Effects of leukemia inhibitory factor on bone resorption and DNA synthesis in neonatal mouse calvaria. ( Cornish, J; Lowe, C; Martin, TJ; Reid, IR, 1991) |
| "The participation of collagenase in bone resorption has been investigated by assaying the procollagenase extracted from fetal mouse calvaria cultured under a variety of conditions, and by evaluating its ability to degrade bone collagen." | 1.27 | Bone-resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue. ( Delaisse, JM; Eeckhout, Y; Vaes, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motiur Rahman, M | 1 |
| Takeshita, S | 1 |
| Matsuoka, K | 1 |
| Kaneko, K | 1 |
| Naoe, Y | 1 |
| Sakaue-Sawano, A | 1 |
| Miyawaki, A | 1 |
| Ikeda, K | 1 |
| O'Brien, W | 1 |
| Fissel, BM | 1 |
| Maeda, Y | 1 |
| Yan, J | 1 |
| Ge, X | 1 |
| Gravallese, EM | 1 |
| Aliprantis, AO | 1 |
| Charles, JF | 1 |
| Krishnamoorthy, P | 1 |
| Alyaarubi, S | 1 |
| Abish, S | 1 |
| Gale, M | 1 |
| Albuquerque, P | 1 |
| Jabado, N | 1 |
| Lorenzo, JA | 2 |
| Raisz, LG | 3 |
| Hock, JM | 1 |
| Hill, PA | 1 |
| Buttle, DJ | 1 |
| Jones, SJ | 1 |
| Boyde, A | 1 |
| Murata, M | 1 |
| Reynolds, JJ | 1 |
| Meikle, MC | 1 |
| Conaway, HH | 2 |
| Grigorie, D | 1 |
| Lerner, UH | 3 |
| Ransjö, M | 2 |
| Chen, D | 1 |
| Waite, LC | 1 |
| Pierce, WM | 1 |
| Matsunaga, T | 1 |
| Inoue, H | 1 |
| Kojo, T | 1 |
| Hatano, K | 1 |
| Tsujisawa, T | 1 |
| Uchiyama, C | 1 |
| Uchida, Y | 1 |
| van Leeuwen, JP | 1 |
| Birkenhäger, JC | 1 |
| van den Bemd, GJ | 1 |
| Buurman, CJ | 1 |
| Staal, A | 1 |
| Bos, MP | 1 |
| Pols, HA | 1 |
| Ljunggren, O | 1 |
| Klaushofer, K | 1 |
| Hoffmann, O | 1 |
| Peterlik, M | 1 |
| Simmons, HA | 1 |
| Lowe, C | 1 |
| Cornish, J | 1 |
| Martin, TJ | 1 |
| Reid, IR | 1 |
| Delaisse, JM | 1 |
| Eeckhout, Y | 1 |
| Vaes, G | 1 |
| Quinton, J | 1 |
| Sousa, S | 1 |
| Krieger, NS | 1 |
| Stathopoulos, VM | 1 |
| Stern, PH | 1 |
16 other studies available for hydroxyurea and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Proliferation-coupled osteoclast differentiation by RANKL: Cell density as a determinant of osteoclast formation.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Cell Cycle; Cell Differentiation; Cell Proliferation; C | 2015 |
RANK-Independent Osteoclast Formation and Bone Erosion in Inflammatory Arthritis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Arthritis, Experimental; Bone Resorption; Cell Prolif | 2016 |
Primary hyperparathyroidism mimicking vaso-occlusive crises in sickle cell disease.
Topics: Adenoma; Adolescent; Analgesics, Opioid; Anemia, Sickle Cell; Arthralgia; Back Pain; Bone Resorption | 2006 |
DNA synthesis is not necessary for osteoclastic responses to parathyroid hormone in cultured fetal rat long bones.
Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Cell Division; Cells, Cultured; DNA; Fetus; Hydro | 1983 |
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
Topics: Animals; Bone Resorption; Calcitriol; Cells, Cultured; Cysteine Proteinase Inhibitors; Dactinomycin; | 1994 |
Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone.
Topics: Acetazolamide; Acetylglucosaminidase; Animals; Animals, Newborn; Anti-Inflammatory Agents; Bone Reso | 1996 |
Prostaglandin-independent stimulation of bone resorption in mouse calvariae and in isolated rat osteoclasts by thyroid hormones (T4, and T3).
Topics: 6-Ketoprostaglandin F1 alpha; Acetylglucosaminidase; Animals; Bone Matrix; Bone Resorption; Calciton | 1998 |
In vitro bone resorption is dependent on physiological concentrations of zinc.
Topics: Acid Phosphatase; Animals; Bone Resorption; Calcium; Chelating Agents; Chick Embryo; Cyclooxygenase | 1998 |
Disaggregated osteoclasts increase in resorption activity in response to roughness of bone surface.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Bone Matrix; Bone Resorption; Cell Differentiation; | 1999 |
Evidence for the functional involvement of protein kinase C in the action of 1,25-dihydroxyvitamin D3 in bone.
Topics: Alkaloids; Animals; Bone Resorption; Calcitriol; Calcium; Cells, Cultured; Diglycerides; Hydroxyurea | 1992 |
On the role of cyclic AMP as a mediator of bone resorption: gamma-interferon completely inhibits cholera toxin- and forskolin-induced but only partially inhibits parathyroid hormone-stimulated 45Ca release from mouse calvarial bones.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Cholera Toxin; Colforsin; Culture Tec | 1991 |
Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones.
Topics: Animals; Aphidicolin; Bone and Bones; Bone Resorption; Culture Techniques; Female; Fibroblast Growth | 1991 |
Effects of leukemia inhibitory factor on bone resorption and DNA synthesis in neonatal mouse calvaria.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitriol; Calcium; Cell Differentiation; Cell Division; | 1991 |
Bone-resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue.
Topics: Acetazolamide; Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcitriol; Cells, Cultured; Co | 1988 |
Effects of DNA and prostaglandin synthesis inhibitors on the stimulation of bone resorption by epidermal growth factor in fetal rat long-bone cultures.
Topics: Animals; Aphidicolin; Bone Resorption; Diterpenes; DNA Replication; Epidermal Growth Factor; Female; | 1986 |
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dact | 1986 |