hydroxyurea has been researched along with Bacterial Infections in 9 studies
Bacterial Infections: Infections by bacteria, general or unspecified.
| Excerpt | Relevance | Reference |
|---|---|---|
| " prevention of overwhelming bacterial infection, present indications and controversies regarding blood transfusion, prevention of stroke, acute chest syndrome, hydroxyurea therapy--probably the best disease modifying agent at the moment, stem cell transplantation--a cure and certain promising experimental therapies including gene therapy have been discussed in this review." | 4.82 | Advances in management of sickle cell disease. ( Agarwal, MB, 2003) |
| "Primary thrombocytosis is extremely rare in childhood, mostly diagnosed at the beginning of the second decade of life." | 2.43 | Primary and secondary thrombocytosis in childhood. ( Dame, C; Sutor, AH, 2005) |
| "Sickle cell disease is a recessively inherited condition in which synthesis of haemoglobin is abnormal." | 2.41 | Acute complications of sickle cell disease in children. ( , 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jordan, LC | 1 |
| Casella, JF | 1 |
| DeBaun, MR | 1 |
| Agarwal, MB | 1 |
| Dame, C | 1 |
| Sutor, AH | 1 |
| Bégué, P | 1 |
| Castello-Herbreteau, B | 1 |
| Griffith, DP | 1 |
| Burr, RG | 1 |
| Gunz, FW | 2 |
| Levi, JA | 2 |
| Vincent, PC | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial[NCT00072761] | Phase 3 | 196 participants (Actual) | Interventional | 2004-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary end point was the recurrence of infarct or hemorrhage as determined by neuroimaging, clinical evidence of permanent neurologic injury, or both. A new infarct had to meet the criteria for a silent cerebral infarction; an enlarged silent cerebral infarct was defined as a previously identified silent cerebral infarct that increased by at least 3 mm along any linear dimension in any plane on MRI. (NCT00072761)
Timeframe: From study entry to study exit
| Intervention | infarct recurrence per 100 person years (Number) |
|---|---|
| Transfusion Group | 2.0 |
| Observation Group | 4.8 |
6 reviews available for hydroxyurea and Bacterial Infections
| Article | Year |
|---|---|
Prospects for primary stroke prevention in children with sickle cell anaemia.
Topics: Adolescent; Anemia, Sickle Cell; Antisickling Agents; Bacterial Infections; Blood Transfusion; Brain | 2012 |
Advances in management of sickle cell disease.
Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Antisickling Agents; Bacterial Infections; Blood Tra | 2003 |
Primary and secondary thrombocytosis in childhood.
Topics: Adolescent; Bacterial Infections; Blood Platelets; Child; Child, Preschool; Humans; Hydroxyurea; Inf | 2005 |
Acute complications of sickle cell disease in children.
Topics: Abdominal Pain; Acute Disease; Adolescent; Analgesics; Anemia, Aplastic; Anemia, Sickle Cell; Animal | 2001 |
[Sickle cell disease: from childhood to adolescence. Management in 2001].
Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Bacterial Infections; Child; Humans; Hydroxyurea; In | 2001 |
Urease stones.
Topics: Adult; Aged; Bacterial Infections; Female; Humans; Hydroxamic Acids; Hydroxyurea; Male; Proteus Infe | 1979 |
3 other studies available for hydroxyurea and Bacterial Infections
| Article | Year |
|---|---|
Inhibition of urease by miscellaneous ions and compounds. Implications for the therapy of infection-induced urolithiasis.
Topics: Bacterial Infections; Humans; Hydroxamic Acids; Hydroxyurea; In Vitro Techniques; Ions; Kanamycin; S | 1977 |
The outlook for the adult with acute leukaemia, 1972.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Cytarabine; Drug Combinations; Female; | 1972 |
Proceedings: Treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Allopurinol; Anti-Bacterial Agents; Bacterial Infections; Child; Cytarabine; D | 1974 |