hydroxyurea has been researched along with Autosomal Chromosome Disorders in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with sickle cell anemia were treated with daily doses of hydroxyurea, to assess pharmacokinetics, toxicity, and increase in fetal hemoglobin (Hb) production in response to the drug." | 2.67 | Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia. ( Ballas, SK; Charache, S; Dover, GJ; Eckert, S; Koshy, M; Milner, PF; Moore, RD; Orringer, EP; Phillips, G; Platt, OS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, H | 1 |
| Hara, T | 1 |
| Tsurumi, H | 1 |
| Tanabashi, S | 1 |
| Moriwaki, H | 1 |
| Maloisel, F | 1 |
| Uettwiller, F | 1 |
| Laplace, A | 1 |
| Lioure, B | 1 |
| Herbrecht, R | 1 |
| Mark, M | 1 |
| Dufour, P | 1 |
| Charache, S | 1 |
| Dover, GJ | 1 |
| Moore, RD | 1 |
| Eckert, S | 1 |
| Ballas, SK | 1 |
| Koshy, M | 1 |
| Milner, PF | 1 |
| Orringer, EP | 1 |
| Phillips, G | 1 |
| Platt, OS | 1 |
| Von Hoff, DD | 1 |
| McGill, JR | 1 |
| Forseth, BJ | 1 |
| Davidson, KK | 1 |
| Bradley, TP | 1 |
| Van Devanter, DR | 1 |
| Wahl, GM | 1 |
| Landaw, SA | 1 |
| Ottolenghi, F | 1 |
| Andreassi, L | 1 |
| Fahmy, OG | 1 |
| Fahmy, MJ | 1 |
| Long, DL | 1 |
| Pierre, RV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)[NCT00000586] | Phase 3 | 0 participants | Interventional | 1992-01-31 | Completed | ||
| Evaluation of Potential Synergy of Combining Hydroxyurea With Nitric Oxide Donors on Fetal Hemoglobin Synthesis in Patients With Sickle Cell Anemia[NCT00056433] | Phase 1 | 39 participants (Actual) | Interventional | 2003-03-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxyurea and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia.
Topics: Adult; Alanine Transaminase; Anemia, Sickle Cell; Chromosome Aberrations; Chromosome Disorders; Dose | 1992 |
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia.
Topics: Adult; Alanine Transaminase; Anemia, Sickle Cell; Chromosome Aberrations; Chromosome Disorders; Dose | 1992 |
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia.
Topics: Adult; Alanine Transaminase; Anemia, Sickle Cell; Chromosome Aberrations; Chromosome Disorders; Dose | 1992 |
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia.
Topics: Adult; Alanine Transaminase; Anemia, Sickle Cell; Chromosome Aberrations; Chromosome Disorders; Dose | 1992 |
7 other studies available for hydroxyurea and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Chronic neutrophilic leukemia with congenital Robertsonian translocation successfully treated with allogeneic bone marrow transplantation in a young man.
Topics: Bone Marrow Transplantation; Cell Transformation, Neoplastic; Chromosome Disorders; Chromosomes, Hum | 2009 |
Emergence of unusual cytogenetic abnormalities under interferon-alpha therapy in patients with chronic myelogenous leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Busulfan; Chromosome Aberrations; Chromo | 1999 |
Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity.
Topics: Animals; Cell Nucleus; Chromosome Aberrations; Chromosome Disorders; Extrachromosomal Inheritance; G | 1992 |
Acute leukemia in polycythemia vera.
Topics: Acute Disease; Antigens, Neoplasm; Bloodletting; Chlorambucil; Chromosome Aberrations; Chromosome Di | 1986 |
[Limitations and risks of therapy of psoriasis with amethopterin and hydroxyurea].
Topics: Adult; Aged; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrat | 1971 |
Hydroxylamine and derivatives: cytotoxicity without mutagenicity in cellular genetic systems.
Topics: Animals; Antineoplastic Agents; Chromosome Aberrations; Chromosome Disorders; Drosophila melanogaste | 1970 |
Autosomal monosomy mosaicism in human bone marrow aspirate. Report of a case.
Topics: Aged; Aneuploidy; Bone Marrow; Bone Marrow Cells; Carcinoma; Chromosome Aberrations; Chromosome Diso | 1968 |