hydroxyurea has been researched along with Arthritis, Rheumatoid in 18 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable side effect, we investigated whether dietary GLA would suppress biosynthesis of PMN-LTB4 isolated from asthma patients and attenuate asthma." | 9.11 | Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. ( Gershwin, ME; Morrissey, BM; Naguwa, S; Vang, K; Watnik, M; Wineinger, J; Ziboh, VA, 2004) |
| "To obtain preliminary evidence on the safety and efficacy of low dose hydroxyurea as a treatment for rheumatoid arthritis (RA)." | 9.08 | A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis. ( Albert, DA; Ehrlich, LS; Thalji, K; Whitman, K, 1995) |
| "The effects of zileuton, a new 5-lipoxygenase inhibitor, on leukotriene generation and clinical response in rheumatoid arthritis (RA) was studied in a 4-week randomized double blind placebo controlled study at 2 academic rheumatology centers." | 9.07 | Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Henson, B; Kremer, JM; Maier, AL; Petrillo, G; Rubin, P; Sperling, R; Weinblatt, ME, 1992) |
| " Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable side effect, we investigated whether dietary GLA would suppress biosynthesis of PMN-LTB4 isolated from asthma patients and attenuate asthma." | 5.11 | Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. ( Gershwin, ME; Morrissey, BM; Naguwa, S; Vang, K; Watnik, M; Wineinger, J; Ziboh, VA, 2004) |
| "The pharmacokinetics of zileuton, a novel selective 5-lipoxygenase inhibitor, were studied in 37 patients with rheumatoid arthritis after administration of 200 mg, 400 mg, and 600 mg, zileuton for 4 weeks." | 5.08 | Population pharmacokinetics of zileution, a selective 5-lipoxygenase inhibitor, in patients with rheumatoid arthritis. ( Awni, WM; Brandwein, SR; Dube, LM; Granneman, GR; Locke, CS, 1995) |
| "To obtain preliminary evidence on the safety and efficacy of low dose hydroxyurea as a treatment for rheumatoid arthritis (RA)." | 5.08 | A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis. ( Albert, DA; Ehrlich, LS; Thalji, K; Whitman, K, 1995) |
| "The effects of zileuton, a new 5-lipoxygenase inhibitor, on leukotriene generation and clinical response in rheumatoid arthritis (RA) was studied in a 4-week randomized double blind placebo controlled study at 2 academic rheumatology centers." | 5.07 | Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Henson, B; Kremer, JM; Maier, AL; Petrillo, G; Rubin, P; Sperling, R; Weinblatt, ME, 1992) |
| "An electronic search encompassing MEDLINE, PubMed, Cochrane Library, and Scopus was completed using the following search terms: rheumatoid arthritis; systemic sclerosis; systemic lupus erythematosus; antineutrophil cytoplasmic antibody-associated vasculitis; mixed connective tissue disease; antiphospholipid syndrome; pyoderma gangrenosum; thromboangiitis obliterans; cryoglobulinemia; hydroxyurea; sickle cell; atrophie blanche; livedoid vasculitis; cholesterol emboli; calciphylaxis; antiphospholipid antibodies; prothrombotic; combined with the terms: chronic wound and leg ulcer." | 4.95 | Vasculitic and autoimmune wounds. ( Angra, D; McNish, S; Rahimi, H; Shanmugam, VK, 2017) |
| " Eosinophilic esophagitis and pharyngitis were diagnosed, and the patient was administered corticosteroids and hydroxyurea, following which her symptoms resolved." | 3.78 | Eosinophilic esophagitis and pharyngitis presenting as mass lesion in a patient with inactive rheumatoid arthritis. ( Danda, D; Kurian, S; Mathew, J; Ramakrishna, BS; Sandhya, P, 2012) |
| " After their base-line blood levels had been assessed, 3 patients with classical rheumatoid arthritis (according to ARA criteria; American Rheumatism Association) received 500 mg of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen) daily (in capsules)." | 3.65 | [Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments]. ( Tausch, G, 1975) |
| "Rheumatoid arthritis was considered for centuries to be a nuisance condition, limiting in its effects on an individual's range of motion and the source of considerable distress, but not a life-threatening disease." | 2.40 | Emerging treatments for rheumatoid arthritis. ( Schiff, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shallis, RM | 1 |
| Xu, ML | 1 |
| Curtis, SA | 1 |
| Medoff, E | 1 |
| Mixon, R | 1 |
| Folkers, A | 1 |
| Zeidan, AM | 1 |
| Shanmugam, VK | 1 |
| Angra, D | 1 |
| Rahimi, H | 1 |
| McNish, S | 1 |
| Anderson, GD | 1 |
| Keys, KL | 1 |
| De Ciechi, PA | 1 |
| Masferrer, JL | 1 |
| Ayvaz, OC | 1 |
| Yavasoglu, I | 1 |
| Kadikoylu, G | 1 |
| Bozkurt, G | 1 |
| Bolaman, Z | 1 |
| Sandhya, P | 1 |
| Danda, D | 1 |
| Mathew, J | 1 |
| Kurian, S | 1 |
| Ramakrishna, BS | 1 |
| Ziboh, VA | 1 |
| Naguwa, S | 1 |
| Vang, K | 1 |
| Wineinger, J | 1 |
| Morrissey, BM | 1 |
| Watnik, M | 1 |
| Gershwin, ME | 1 |
| Michel, M | 1 |
| Habibi, A | 1 |
| Godeau, B | 1 |
| Bachir, D | 1 |
| Lahary, A | 1 |
| Galacteros, F | 1 |
| Fifi-Mah, A | 1 |
| Arfi, S | 1 |
| Awni, WM | 1 |
| Granneman, GR | 1 |
| Locke, CS | 1 |
| Brandwein, SR | 1 |
| Dube, LM | 1 |
| Ehrlich, LS | 1 |
| Thalji, K | 1 |
| Whitman, K | 1 |
| Albert, DA | 1 |
| McGill, KA | 1 |
| Busse, WW | 1 |
| Morris, AJ | 1 |
| Russell, AS | 1 |
| Ramos-Remus, C | 1 |
| Schiff, M | 1 |
| Santais, MC | 1 |
| Callens, E | 1 |
| Djebbar, R | 1 |
| Ruff, F | 1 |
| Navarra, P | 1 |
| Preziosi, P | 1 |
| Brzezińska, B | 1 |
| Graff-Wróblewska, T | 1 |
| Juszczyk, T | 1 |
| Tausch, G | 1 |
| Weinblatt, ME | 1 |
| Kremer, JM | 1 |
| Coblyn, JS | 1 |
| Helfgott, S | 1 |
| Maier, AL | 1 |
| Petrillo, G | 1 |
| Henson, B | 1 |
| Rubin, P | 1 |
| Sperling, R | 1 |
6 reviews available for hydroxyurea and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Conviction in the face of affliction: a case series of Jehovah's Witnesses with myeloid malignancies.
Topics: Aged; Anemia, Macrocytic; Antimetabolites, Antineoplastic; Arthritis, Rheumatoid; Azacitidine; Blood | 2018 |
Vasculitic and autoimmune wounds.
Topics: Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antiphospholipid Sy | 2017 |
Zileuton.
Topics: Arthritis, Rheumatoid; Asthma; Humans; Hydroxyurea; Lipoxygenase Inhibitors | 1996 |
Emerging treatments for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; | 1997 |
[Potential importance of antileukotrienes in the treatment of asthma and other inflammatory diseases: apropos of a new pharmacological class].
Topics: Acetophenones; Adult; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthr | 1998 |
Hydroxyurea: new insights on an old drug.
Topics: Arthritis, Rheumatoid; Hematologic Diseases; Humans; Hydroxyurea; Neoplasms; Ribonucleotide Reductas | 1999 |
4 trials available for hydroxyurea and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Asthma; Dietary Supplements; Double-Blind Method; Fatty Acids; F | 2004 |
Population pharmacokinetics of zileution, a selective 5-lipoxygenase inhibitor, in patients with rheumatoid arthritis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Hydroxyurea; K | 1995 |
A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Hydroxyurea; Middle Aged; Pilot Pr | 1995 |
Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blind Method; Fe | 1992 |
8 other studies available for hydroxyurea and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Combination therapies that inhibit cyclooxygenase-2 and leukotriene synthesis prevent disease in murine collagen induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arthritis, Experiment | 2009 |
Thrombocytosis in rheumatoid arthritis: JAK2V617F-positive essential thrombocythemia.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Comorbidity; Humans; Hydroxyurea; Janus Kinase | 2012 |
Eosinophilic esophagitis and pharyngitis presenting as mass lesion in a patient with inactive rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Deglutition Disorders; Drug Therapy, Combination; Eosinophilic Esophag | 2012 |
Characteristics and outcome of connective tissue diseases in patients with sickle-cell disease: report of 30 cases.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Arthritis, Rheumatoid; Blood Transfusion; Drug Ther | 2008 |
Combination drug therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Hydroxyurea | 1996 |
Combination drug therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chelation Therapy; Drug Therapy, Combination; Humans; Hydroxyurea | 1997 |
[Evaluation of therapeutic value of hydroxycarbamid "Polfa" (hydroxyurea) in rheumatoid arthritis].
Topics: Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Industry; Female; Humans; Hydroxyurea; Male; Midd | 1978 |
[Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cobalt Radioisotopes; DNA; DNA Repair; Humans; Hydroxyurea; | 1975 |