hydroxyurea has been researched along with Anoxemia in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic stroke is characterized by high morbidity, disability, and mortality." | 5.91 | Enhanced brain delivery of hypoxia-sensitive liposomes by hydroxyurea for rescue therapy of hyperacute ischemic stroke. ( Hong, Y; Hu, F; Jin, X; Ke, J; Li, S; Shang, X; Wang, K; Wen, L; Wu, X; Xu, Y; Yuan, H; Zhou, W, 2023) |
| "The root cause of sickle cell disease is a single beta-globin gene mutation coding for the sickle beta-hemoglobin chain." | 2.44 | Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches. ( Steinberg, MH, 2008) |
| "Ischemic stroke is characterized by high morbidity, disability, and mortality." | 1.91 | Enhanced brain delivery of hypoxia-sensitive liposomes by hydroxyurea for rescue therapy of hyperacute ischemic stroke. ( Hong, Y; Hu, F; Jin, X; Ke, J; Li, S; Shang, X; Wang, K; Wen, L; Wu, X; Xu, Y; Yuan, H; Zhou, W, 2023) |
| "Sickle cell anemia is a type of hemoglobinopathy characterized by a specific mutation in the beta globin gene with the consequent generation of an unstable hemoglobin that crystallizes in a state of hypoxia." | 1.62 | [Disease genotype, haplotypes, diagnosis and associated studies in sickle cell anemia]. ( Benavides-Benítez, E; Bernal, JE; Briceño-Balcázar, I; Díaz-Matallana, M; Márquez-Benítez, Y; Martínez-Lozano, JC, 2021) |
| " Our results showed, for the first time, a significantly increased expression of HIF-1α and VEGF genes in patients with SCA and an inverse dose-response relationship with hydroxyurea therapy." | 1.56 | Gene expression of HIF-1α and VEGF in response to hypoxia in sickle cell anaemia: Influence of hydroxycarbamide. ( Lemes, RPG; Pedrosa, AM, 2020) |
| "In cultured ovarian cancer cells, 5-LOX metabolites were increased under hypoxic conditons." | 1.42 | Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration. ( Fan, B; Gao, W; Li, B; Li, M; Liu, H; Qu, X; Shao, Q; Wang, Q; Wen, Z; Xie, Q; Yang, Y; Yu, J; Zhao, F, 2015) |
| "Chronic hypoxemia is a common manifestation among patients with sickle cell anemia (SCA) who develop chronic lung disease." | 1.35 | Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyurea. ( Aygun, B; Koumbourlis, AC; Singh, SA, 2008) |
| "The EMH-related pleural effusion is rarely referred to in the literature of thalassemia." | 1.33 | Extramedullary hematopoiesis-related pleural effusion: the case of beta-thalassemia. ( Aessopos, A; Farmakis, D; Kati, M; Moyssakis, I; Polonifi, K; Tassiopoulos, S; Tsironi, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Díaz-Matallana, M | 1 |
| Márquez-Benítez, Y | 1 |
| Martínez-Lozano, JC | 1 |
| Briceño-Balcázar, I | 1 |
| Benavides-Benítez, E | 1 |
| Bernal, JE | 1 |
| Wang, K | 1 |
| Zhou, W | 1 |
| Jin, X | 1 |
| Shang, X | 1 |
| Wu, X | 1 |
| Wen, L | 1 |
| Li, S | 1 |
| Hong, Y | 1 |
| Ke, J | 1 |
| Xu, Y | 1 |
| Yuan, H | 1 |
| Hu, F | 1 |
| Pedrosa, AM | 1 |
| Lemes, RPG | 1 |
| Liguoro, I | 1 |
| Arigliani, M | 1 |
| Singh, B | 1 |
| Rees, D | 1 |
| Inusa, BPD | 1 |
| Gupta, A | 1 |
| Ip, H | 1 |
| Kesse-Adu, R | 1 |
| Howard, J | 1 |
| Hart, N | 1 |
| Wen, Z | 1 |
| Liu, H | 1 |
| Li, M | 1 |
| Li, B | 1 |
| Gao, W | 1 |
| Shao, Q | 1 |
| Fan, B | 1 |
| Zhao, F | 1 |
| Wang, Q | 1 |
| Xie, Q | 1 |
| Yang, Y | 1 |
| Yu, J | 1 |
| Qu, X | 1 |
| Lopes, FC | 1 |
| Ferreira, R | 1 |
| Albuquerque, DM | 1 |
| Silveira, AA | 1 |
| Costa, R | 1 |
| Soares, R | 1 |
| Costa, FF | 1 |
| Conran, N | 1 |
| Steinberg, MH | 1 |
| Economopoulou, M | 1 |
| Langer, HF | 1 |
| Celeste, A | 1 |
| Orlova, VV | 1 |
| Choi, EY | 1 |
| Ma, M | 1 |
| Vassilopoulos, A | 1 |
| Callen, E | 1 |
| Deng, C | 1 |
| Bassing, CH | 1 |
| Boehm, M | 1 |
| Nussenzweig, A | 1 |
| Chavakis, T | 1 |
| Chernoff, N | 1 |
| Rogers, JM | 1 |
| Aessopos, A | 1 |
| Tassiopoulos, S | 1 |
| Farmakis, D | 1 |
| Moyssakis, I | 1 |
| Kati, M | 1 |
| Polonifi, K | 1 |
| Tsironi, M | 1 |
| Singh, SA | 1 |
| Koumbourlis, AC | 1 |
| Aygun, B | 1 |
| Bates, N | 1 |
| Chimploy, K | 1 |
| Tassotto, ML | 1 |
| Mathews, CK | 1 |
| Vacek, A | 1 |
| Tacev, T | 1 |
| Hofer, M | 1 |
| Wetter, TJ | 1 |
| Xiang, Z | 1 |
| Sonetti, DA | 1 |
| Haverkamp, HC | 1 |
| Rice, AJ | 1 |
| Abbasi, AA | 1 |
| Meyer, KC | 1 |
| Dempsey, JA | 1 |
| Yamada, S | 1 |
| Perot, PL | 1 |
| Ducker, TB | 1 |
| Gale, GR | 1 |
| Dawson, KB | 1 |
| Madoc-Jones, H | 1 |
| Mauro, F | 1 |
| Peacock, JH | 1 |
2 reviews available for hydroxyurea and Anoxemia
| Article | Year |
|---|---|
Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches.
Topics: alpha-Thalassemia; Anemia, Sickle Cell; Erythrocyte Membrane; Female; Hemoglobin, Sickle; Humans; Hy | 2008 |
Hypoxia and the Edema Syndrome: elucidation of a mechanism of teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Blister; Chick Embryo; Cocaine; Edema; Epinephrine; Hematoma; | 2010 |
16 other studies available for hydroxyurea and Anoxemia
| Article | Year |
|---|---|
[Disease genotype, haplotypes, diagnosis and associated studies in sickle cell anemia].
Topics: Anemia, Sickle Cell; Haplotypes; Humans; Hydroxyurea; Hypoxia | 2021 |
Enhanced brain delivery of hypoxia-sensitive liposomes by hydroxyurea for rescue therapy of hyperacute ischemic stroke.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Endothelial Cells; Hydroxyurea; Hypoxia; Ischem | 2023 |
Gene expression of HIF-1α and VEGF in response to hypoxia in sickle cell anaemia: Influence of hydroxycarbamide.
Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Antisickling Agents; Case-Control Studies; Female; Gen | 2020 |
Long-term oxygen therapy in children with sickle cell disease and hypoxaemia.
Topics: Adolescent; Anemia, Sickle Cell; Antisickling Agents; Case-Control Studies; Child; Chronic Disease; | 2021 |
Low flow nocturnal oxygen therapy does not suppress haemoglobin levels or increase painful crises in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Erythropoiesis; Erythropoietin; Female; Hemoglobins | 2013 |
Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Line; Cell Line, Tumor; Chemotaxis, Leukocyte; Disease Mo | 2015 |
In vitro and in vivo anti-angiogenic effects of hydroxyurea.
Topics: Anemia, Sickle Cell; Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Human Umbi | 2014 |
Histone H2AX is integral to hypoxia-driven neovascularization.
Topics: Animals; DNA Damage; Endothelium, Vascular; Gene Deletion; Hindlimb; Histones; Humans; Hydroxyurea; | 2009 |
Extramedullary hematopoiesis-related pleural effusion: the case of beta-thalassemia.
Topics: Adult; Atrial Fibrillation; beta-Thalassemia; Blood Transfusion; Chest Tubes; Combined Modality Ther | 2006 |
Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyurea.
Topics: Anemia, Sickle Cell; Antisickling Agents; Child; Chronic Disease; Female; Humans; Hydroxyurea; Hypox | 2008 |
Hydroxycarbamide (hydroxyurea) toxicity in dogs.
Topics: Animals; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyurea; Hypox | 2008 |
Ribonucleotide reductase, a possible agent in deoxyribonucleotide pool asymmetries induced by hypoxia.
Topics: Animals; Cells, Cultured; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguan | 2000 |
Modulation of radioprotective effects of respiratory hypoxia by changing the duration of hypoxia before irradiation and by combining hypoxia and administration of hemopoiesis-stimulating agents.
Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Cobalt Radioisotopes; Dextran Sulfate; Fe | 2001 |
Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.
Topics: Adult; Cell Count; Exercise; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypoxia; Inflamm | 2002 |
Effect of prolonged continuous intracarotid arterial perfusion of hydroxyurea on the normal monkey brain.
Topics: Animals; Brain; Carotid Arteries; Glioblastoma; Haplorhini; Hydroxyurea; Hypoxia; Macaca; Methods; P | 1974 |
Studies on the radiobiology of a rat sarcoma treated in situ and assayed in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Clone Cells; Hydroxyurea; Hypoxia; Neoplasm Transplantation | 1973 |