hydroxyurea has been researched along with Aneuploid in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyurea induces mitotic gene conversion, mitotic crossing-over, reverse mutation, respiration-deficient petite mutants and aneuploidy in growing cultures of Saccharomyces cerevisiae." | 7.67 | Aneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae. ( Goin, CJ; Mayer, VW; Zimmermann, FK, 1986) |
| "It remains elusive whether aneuploidy affects the drug sensitivity of hydroxyurea." | 5.51 | p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer. ( Fang, X; Fu, Y; Liu, Y; Wu, F; Yin, H; Yu, D; Zhang, H; Zong, L, 2019) |
| "Hydroxyurea induces mitotic gene conversion, mitotic crossing-over, reverse mutation, respiration-deficient petite mutants and aneuploidy in growing cultures of Saccharomyces cerevisiae." | 3.67 | Aneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae. ( Goin, CJ; Mayer, VW; Zimmermann, FK, 1986) |
| "Median survival of patients with myelofibrosis with myeloid metaplasia (MMM) ranges from 3." | 2.41 | Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000. ( Cervantes, F, 2001) |
| "It remains elusive whether aneuploidy affects the drug sensitivity of hydroxyurea." | 1.51 | p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer. ( Fang, X; Fu, Y; Liu, Y; Wu, F; Yin, H; Yu, D; Zhang, H; Zong, L, 2019) |
| "Because aneuploidy simultaneously affects many genes, it has the potential to confer multiple phenotypes to the same cells." | 1.51 | Aneuploidy Enables Cross-Adaptation to Unrelated Drugs. ( Berman, J; Cao, Y; Pavelka, N; Tan, ASM; Teoh, F; Yang, F, 2019) |
| "Gadd45a deletion allows another form of genomic instability, gene amplification, when p21 (Cdkn1a gene product) is deleted also." | 1.33 | Genomic instability in Gadd45a-/- cells is coupled with S-phase checkpoint defects. ( Fornace, AJ; Hollander, MC; Patterson, AD; Philburn, RT; Wyatt, MA, 2005) |
| "The effect of interferon-alpha (IFN) for chronic myeloid leukemia (CML) in the chronic phase (CP) was retrospectively evaluated in comparison with that of busulfan (BU) or hydroxyurea (HU) given alone." | 1.30 | A cytogenetic and fluorescence in situ hybridization evaluation of interferon-alpha in the treatment of chronic myeloid leukemia. ( Itoh, T; Kakishita, E; Takemoto, Y; Tamura, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, X | 1 |
| Xu, Y | 1 |
| Guo, R | 2 |
| Xu, R | 1 |
| Fu, C | 1 |
| Xing, M | 1 |
| Sasanuma, H | 1 |
| Li, Q | 1 |
| Takata, M | 1 |
| Takeda, S | 1 |
| Xu, D | 1 |
| Fang, X | 1 |
| Yin, H | 1 |
| Zhang, H | 1 |
| Wu, F | 1 |
| Liu, Y | 1 |
| Fu, Y | 1 |
| Yu, D | 1 |
| Zong, L | 1 |
| Yang, F | 1 |
| Teoh, F | 1 |
| Tan, ASM | 1 |
| Cao, Y | 1 |
| Pavelka, N | 1 |
| Berman, J | 1 |
| Morel, F | 1 |
| Bris, MJ | 1 |
| Herry, A | 1 |
| Calvez, GL | 1 |
| Marion, V | 1 |
| Abgrall, JF | 1 |
| Berthou, C | 1 |
| Braekeleer, MD | 1 |
| Hollander, MC | 1 |
| Philburn, RT | 1 |
| Patterson, AD | 1 |
| Wyatt, MA | 1 |
| Fornace, AJ | 1 |
| Lentini, L | 1 |
| Iovino, F | 1 |
| Amato, A | 1 |
| Di Leonardo, A | 1 |
| Abdu, U | 1 |
| Klovstad, M | 1 |
| Butin-Israeli, V | 1 |
| Bakhrat, A | 1 |
| Schüpbach, T | 1 |
| Itoh, T | 1 |
| Tamura, S | 1 |
| Takemoto, Y | 1 |
| Kakishita, E | 1 |
| Cervantes, F | 1 |
| Shen, Y | 1 |
| Xue, Y | 1 |
| Li, J | 1 |
| Guo, Y | 1 |
| Wu, Y | 1 |
| Pan, J | 1 |
| Mayer, VW | 1 |
| Goin, CJ | 1 |
| Zimmermann, FK | 1 |
| Long, DL | 1 |
| Pierre, RV | 1 |
1 review available for hydroxyurea and Aneuploid
| Article | Year |
|---|---|
Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000.
Topics: Aged; Anemia; Aneuploidy; Angiogenesis Inhibitors; Bone Marrow Transplantation; Case Management; Com | 2001 |
11 other studies available for hydroxyurea and Aneuploid
| Article | Year |
|---|---|
Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.
Topics: Aneuploidy; Animals; Bone Marrow Failure Disorders; Cell Line, Transformed; Chickens; Chromosome Bre | 2021 |
p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer.
Topics: Aneuploidy; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Drug Resistance | 2019 |
Aneuploidy Enables Cross-Adaptation to Unrelated Drugs.
Topics: Adaptation, Biological; Aneuploidy; Animals; Antifungal Agents; Antineoplastic Agents; Calcineurin; | 2019 |
Double minutes containing amplified bcr-abl fusion gene in a case of chronic myeloid leukemia treated by imatinib.
Topics: Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast | 2003 |
Genomic instability in Gadd45a-/- cells is coupled with S-phase checkpoint defects.
Topics: Aneuploidy; Animals; Aspartic Acid; Cell Cycle Proteins; Cell Line; Centrosome; Chromosome Segregati | 2005 |
Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts.
Topics: Aneuploidy; Animals; Cell Line; Cells, Cultured; Centrosome; Chromosomal Instability; Fibroblasts; H | 2006 |
An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses.
Topics: Aneuploidy; Animals; Apoptosis; Body Patterning; Cell Cycle; Cell Cycle Proteins; DNA Damage; Drosop | 2007 |
A cytogenetic and fluorescence in situ hybridization evaluation of interferon-alpha in the treatment of chronic myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aneuploidy; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Bone Marr | 1999 |
Pentasomy 8q resulting from duplication of isochromosome 8q in chronic myelomonocytic leukemia.
Topics: Aneuploidy; Chromosomes, Human, Pair 8; Cytogenetic Analysis; Fatal Outcome; Gene Duplication; Human | 2002 |
Aneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae.
Topics: Aneuploidy; Cell Survival; Cycloheximide; Drug Resistance, Microbial; Gene Conversion; Hydroxyurea; | 1986 |
Autosomal monosomy mosaicism in human bone marrow aspirate. Report of a case.
Topics: Aged; Aneuploidy; Bone Marrow; Bone Marrow Cells; Carcinoma; Chromosome Aberrations; Chromosome Diso | 1968 |