Page last updated: 2024-10-28

hydroxyurea and Anemia

hydroxyurea has been researched along with Anemia in 42 studies

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"We present a case of oral ulceration in a patient with essential thrombocythaemia, that proved to be secondary to treatment with hydroxyurea."8.80Oral ulcers caused by hydroxyurea. ( Lindsey, L; Paleri, V, 2000)
"Eighty-five patients with extensive chronic plaque psoriasis, unresponsive to conventional topical therapy, were treated with long-term hydroxyurea in a dose of 0."7.67Hydroxyurea in the management of therapy resistant psoriasis. ( Cotterill, JA; Goodfield, MJ; Layton, AM; Sheehan-Dare, RA, 1989)
" Black pigment gallstones caused by elevated bilirubin excretion are common."4.86Gastrointestinal and hepatic complications of sickle cell disease. ( Ebert, EC; Hagspiel, KD; Nagar, M, 2010)
"We present a case of oral ulceration in a patient with essential thrombocythaemia, that proved to be secondary to treatment with hydroxyurea."4.80Oral ulcers caused by hydroxyurea. ( Lindsey, L; Paleri, V, 2000)
"Eighty-five patients with extensive chronic plaque psoriasis, unresponsive to conventional topical therapy, were treated with long-term hydroxyurea in a dose of 0."3.67Hydroxyurea in the management of therapy resistant psoriasis. ( Cotterill, JA; Goodfield, MJ; Layton, AM; Sheehan-Dare, RA, 1989)
"Median survival of patients with myelofibrosis with myeloid metaplasia (MMM) ranges from 3."2.41Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000. ( Cervantes, F, 2001)
"Idiopathic myelofibrosis is the least common and carries the worst prognosis of the chronic myeloproliferative disorders."2.40Pathogenesis and management of idiopathic myelofibrosis. ( Reilly, JT, 1998)
"Idiopathic myelofibrosis is reviewed from several aspects."2.38Idiopathic myelofibrosis: historical review, diagnosis and management. ( Weinstein, IM, 1991)
"The slower appearance of CFU-E in polycythemia was corrected by the injection of erythropoietin (Ep) 8 h prior to sacrifice, but an absolute increase in colony number only occurred when Ep was injected 24 h previously."1.27Studies on the kinetics of the erythroid colony-forming cell. ( Lipschitz, DA; Udupa, KB, 1986)
"mm."1.25Hydroxyurea in stage D carcinoma of the prostate: a pilot study. ( Cromie, W; Lerner, H; Longo, S; Malloy, T, 1975)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199021 (50.00)18.7374
1990's7 (16.67)18.2507
2000's6 (14.29)29.6817
2010's7 (16.67)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Pan, DQ1
Zhao, WS1
Yin, CX1
He, H1
Lin, R1
Zhao, K1
Ye, JY1
Liu, QF1
Dai, M1
Chang, L1
Duan, MH1
Park, S1
Hamel, JF1
Toma, A1
Kelaidi, C1
Thépot, S1
Campelo, MD1
Santini, V1
Sekeres, MA1
Balleari, E1
Kaivers, J1
Sapena, R1
Götze, K1
Müller-Thomas, C1
Beyne-Rauzy, O1
Stamatoullas, A1
Kotsianidis, I1
Komrokji, R1
Steensma, DP1
Fensterl, J1
Roboz, GJ1
Bernal, T1
Ramos, F1
Calabuig, M1
Guerci-Bresler, A1
Bordessoule, D1
Cony-Makhoul, P1
Cheze, S1
Wattel, E1
Rose, C1
Vey, N1
Gioia, D1
Ferrero, D1
Gaidano, G1
Cametti, G1
Pane, F1
Sanna, A1
Germing, U1
Sanz, GF1
Dreyfus, F1
Fenaux, P1
Kundu, MC1
Gore, LR1
Maguire, S1
Gilmartin, AG1
Verstovsek, S1
Passamonti, F1
Rambaldi, A1
Barosi, G1
Rosen, PJ1
Rumi, E1
Gattoni, E1
Pieri, L1
Guglielmelli, P1
Elena, C1
He, S1
Contel, N1
Mookerjee, B1
Sandor, V1
Cazzola, M1
Kantarjian, HM1
Barbui, T3
Vannucchi, AM1
Oberoi, S1
Das, R1
Trehan, A1
Ahluwalia, J1
Bansal, D1
Malhotra, P1
Marwaha, RK1
Bandyopadhyay, D1
Manna, S1
Hajra, A1
Bhattacharya, TD1
Ebert, EC1
Nagar, M1
Hagspiel, KD1
Martínez-Trillos, A1
Gaya, A1
Maffioli, M1
Arellano-Rodrigo, E1
Calvo, X1
Díaz-Beyá, M1
Cervantes, F2
Finazzi, G2
Ruggeri, M1
Rodeghiero, F1
DE BERGSAGEL, DE1
FRENKEL, EP2
ALFREY, CP1
THURMAN, WG2
SKINNER, WN1
SMILEY, JD1
WATKINS, WL1
GRIFFITH, KM1
SEARS, ME1
HOWE, CD1
SAMUELS, ML1
La Spina, M1
Russo, G1
Letvin, NL1
Linch, DC1
Beardsley, GP1
McIntyre, KW1
Nathan, DG2
Lee, EW1
Kocsis, JJ1
Snyder, R1
Mayhew, CN1
Phillips, JD1
Greenberg, RN1
Birch, NJ1
Elford, HL1
Gallicchio, VS1
Reilly, JT1
Hirri, HM1
Green, PJ1
Paleri, V1
Lindsey, L1
Bowers, M1
Lerner, H1
Malloy, T1
Cromie, W1
Longo, S1
McDonagh, KT1
Dover, GJ1
Donahue, RE1
Agricola, B1
Byrne, E1
Nienhuis, AW1
Balducci, L1
Hardy, CL1
Weinstein, IM1
Ebbe, S1
Stamatoyannopoulos, G1
Veith, R1
Galanello, R1
Papayannopoulou, T1
Datta, MC1
Dowla, HA1
Spears, HJ1
Layton, AM1
Sheehan-Dare, RA1
Goodfield, MJ1
Cotterill, JA1
Alter, BP2
Wagner, CK2
Susser, LS1
Weinberg, RS1
Udupa, KB1
Lipschitz, DA1
Mason, JE1
DeVita, VT1
Canellos, GP1
Hodgson, GS1
Moschella, SL1
Greenwald, MA1
Slack, NM1
Jones, R1
Yamamoto, RS1
Weisburger, EK1
Korzis, J1
Card, RT1
Lee, JD1
McGrath, M1
Valberg, LS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Integrated European Platform to Conduct Translational Studies in Myelodysplastic Syndromes Based on the EuroBloodNet Infrastructure[NCT04174547]8,670 participants (Anticipated)Observational2019-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for hydroxyurea and Anemia

ArticleYear
Gastrointestinal and hepatic complications of sickle cell disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:6

    Topics: Anemia; Anemia, Sickle Cell; Antisickling Agents; Bilirubin; Blood Transfusion; Gallstones; Humans;

2010
New drugs for childhood anemia.
    Minerva pediatrica, 2003, Volume: 55, Issue:5

    Topics: Adult; Age Factors; Anemia; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Antibodies, Monoclon

2003
The use of ferrokinetics in the study of experimental anemia.
    Environmental health perspectives, 1981, Volume: 39

    Topics: Anemia; Animals; Benzene; Cytarabine; Erythropoiesis; Hematopoietic Stem Cells; Humans; Hydroxyurea;

1981
Pathogenesis and management of idiopathic myelofibrosis.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cladribine; Combined Modality Therapy; Di

1998
Oral ulcers caused by hydroxyurea.
    The Journal of laryngology and otology, 2000, Volume: 114, Issue:12

    Topics: Aged; Anemia; Humans; Hydroxyurea; Male; Mouth Mucosa; Nucleic Acid Synthesis Inhibitors; Oral Ulcer

2000
Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aged; Anemia; Aneuploidy; Angiogenesis Inhibitors; Bone Marrow Transplantation; Case Management; Com

2001
Efficacy and safety of hydroxyurea in patients with essential thrombocythemia.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Cell Transformation, Neoplastic; Cohort Studies; Female; Fol

2001
Idiopathic myelofibrosis: historical review, diagnosis and management.
    Blood reviews, 1991, Volume: 5, Issue:2

    Topics: Anemia; Bone Marrow; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Diagnosis, Di

1991

Trials

2 trials available for hydroxyurea and Anemia

ArticleYear
A phase 2 study of ruxolitinib, an oral JAK1 and JAK2 Inhibitor, in patients with advanced polycythemia vera who are refractory or intolerant to hydroxyurea.
    Cancer, 2014, Feb-15, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Contraindications; Drug-Related Side Effects and Adverse Rea

2014
Single reversal trial of hydroxyurea (NSC-32065) in 91 patients with advanced cancer.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:1

    Topics: Anemia; Asparaginase; Azaserine; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Drug

1970

Other Studies

32 other studies available for hydroxyurea and Anemia

ArticleYear
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:5

    Topics: Adult; Aged; Anemia; Bone Marrow; Female; Hemoglobins; Humans; Hydroxyurea; Male; Middle Aged; Myelo

2022
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine;

2017
Development and Characterization of a Model for Inducing Fetal Hemoglobin Production in Cynomolgus Macaques (
    Comparative medicine, 2018, 10-01, Volume: 68, Issue:5

    Topics: Anemia; Animals; Disease Models, Animal; Fetal Hemoglobin; Hydroxyurea; Macaca fascicularis; Male; P

2018
HbSD-Punjab: clinical and hematological profile of a rare hemoglobinopathy.
    Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:3

    Topics: Acute Chest Syndrome; Anemia; Antisickling Agents; Child; Child, Preschool; Chromatography, High Pre

2014
Atypical CML with massive splenic infarct: an extremely rare presentation.
    BMJ case reports, 2015, Nov-12, Volume: 2015

    Topics: Abdominal Pain; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Fatal Outcom

2015
Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: results in 40 patients.
    Annals of hematology, 2010, Volume: 89, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antisickling Agents; Bone and Bones; Female; Humans; Hydroxy

2010
Efficacy and safety of long-term use of hydroxyurea in young patients with essential thrombocythemia and a high risk of thrombosis.
    Blood, 2003, May-01, Volume: 101, Issue:9

    Topics: Adolescent; Adult; Anemia; Cohort Studies; Follow-Up Studies; Hemorrhage; Humans; Hydroxyurea; Incid

2003
MEGALOBLASTIC ERYTHROPOIESIS INDUCED BY HYDROXYUREA (NSC-32065).
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Pernicious; Animals; Antineoplastic Agents; Bone Marrow Cells; Bone Marrow Diseases;

1964
STUDIES ON A METABOLIC DEFECT INDUCED BY HYDROXYUREA (NSC-32065).
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Macrocytic; Animals; Antineoplastic Agents; Bone Marrow Cells; Cattle; Cytosine Nucl

1964
STUDY OF SERUM B12 AND FOLATE IN PATIENTS TREATED WITH HYDROXYUREA (NSC-32065).
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Macrocytic; Antineoplastic Agents; Blood Chemical Analysis; Child; Folic Acid; Human

1964
HYDROXYUREA (NSC-32065): RESULTS OF A PHASE I STUDY.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Aplastic; Antineoplastic Agents; Drug Therapy; Hydroxyurea; Leukopenia; Statistics a

1964
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: CANCER OF THE BREAST.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Myelophthisic; Antineoplastic Agents; Breast Neoplasms; Drug Therapy; Erythema; Estr

1964
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: UROLOGIC AND GYNECOLOGIC NEOPLASMS.
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Adenocarcinoma; Anemia; Anemia, Aplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Ther

1964
Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia; Animals; Azacitidine; Bloodletting; DNA; Erythrocyte Count; Fetal Hemoglobin; Globins; Hydro

1984
In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity.
    Stem cells (Dayton, Ohio), 1999, Volume: 17, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Anti-HIV Agents; Benzamidines; Cells, Cultured;

1999
Pure red cell aplasia in a patient with chronic granulocytic leukaemia treated with interferon-alpha.
    Clinical and laboratory haematology, 2000, Volume: 22, Issue:1

    Topics: Aged; Anemia; Blood Transfusion; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 22; Huma

2000
Hydroxyurea.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1997

    Topics: Alopecia; Anemia; Bone Marrow; DNA Replication; Enzyme Inhibitors; HIV Infections; Humans; Hydroxyur

1997
Hydroxyurea in stage D carcinoma of the prostate: a pilot study.
    The Journal of urology, 1975, Volume: 114, Issue:3

    Topics: Adenocarcinoma; Aged; Anemia; Bone Neoplasms; Chlorotrianisene; Estrogens; Humans; Hydroxyurea; Leuk

1975
Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.
    Experimental hematology, 1992, Volume: 20, Issue:10

    Topics: Administration, Oral; Anemia; Animals; Bloodletting; Butyrates; Butyric Acid; Cell Division; Chromat

1992
High proliferation of early hemopoietic progenitors in tumor-bearing mice.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1992, Volume: 60, Issue:2

    Topics: Anemia; Animals; Bone Marrow; Carcinoma; Cell Division; Hematopoiesis; Hematopoietic Cell Growth Fac

1992
Megakaryocyte size and ploidy in thrombocytopenic or megakaryocytopenic mice.
    Progress in clinical and biological research, 1990, Volume: 352

    Topics: Anemia; Animals; Blood Platelets; Hydroxyurea; Immune Sera; Megakaryocytes; Mice; Mice, Mutant Strai

1990
Hb F production in stressed erythropoiesis: observations and kinetic models.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Anemia; Animals; Azacitidine; Cell Cycle; Cell Differentiation; Cytarabine; Erythropoiesis; Fetal He

1985
Hydroxyurea-induced switching of hemoglobin proportions toward newborn values in normal adult rats is blocked by acetylsalicylic acid.
    Progress in clinical and biological research, 1989, Volume: 319

    Topics: Aging; Anemia; Animals; Animals, Newborn; Aspirin; Fetal Hemoglobin; Hemoglobins; Hydroxyurea; Rats;

1989
Hydroxyurea in the management of therapy resistant psoriasis.
    The British journal of dermatology, 1989, Volume: 121, Issue:5

    Topics: Adult; Aged; Anemia; Female; Hemorrhagic Disorders; Humans; Hydroxyurea; Male; Middle Aged; Psoriasi

1989
Modulation of mouse hemoglobin expression by hydroxyurea and erythropoietin in vivo.
    Progress in clinical and biological research, 1989, Volume: 316B

    Topics: Anemia; Animals; Erythrocyte Count; Erythropoietin; Female; Hemoglobins; Hydroxyurea; Mice; Mice, In

1989
A murine model for hemoglobin regulation: hydroxyurea increases mouse minor hemoglobin in vivo.
    Progress in clinical and biological research, 1987, Volume: 251

    Topics: Anemia; Animals; Erythrocyte Count; Gene Expression Regulation; Genes; Globins; Hemoglobin A; Hydrox

1987
Studies on the kinetics of the erythroid colony-forming cell.
    Experimental hematology, 1986, Volume: 14, Issue:5

    Topics: Anemia; Animals; Blood Sedimentation; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay

1986
Thrombocytosis in chronic granulocytic leukemia: incidence and clinical significance.
    Blood, 1974, Volume: 44, Issue:4

    Topics: Anemia; Azauridine; Blood Cell Count; Blood Platelets; Bone Marrow Examination; Busulfan; Cell Trans

1974
Properties of haemopoietic stem cells in phenylhydrazine treated mice.
    Cell and tissue kinetics, 1973, Volume: 6, Issue:2

    Topics: Anemia; Animals; Cell Count; Clone Cells; Dose-Response Relationship, Radiation; Erythrocyte Count;

1973
Psoriasis with hydroxyurea. An 18-month study of 60 patients.
    Archives of dermatology, 1973, Volume: 107, Issue:3

    Topics: Adult; Aged; Anemia; Chemical and Drug Induced Liver Injury; Drug Resistance; Female; Humans; Hydrox

1973
Chronic administration of hydroxylamine and derivatives in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:4

    Topics: Anemia; Animals; Hydroxylamines; Hydroxyurea; Mammary Neoplasms, Experimental; Mice; Ossification, H

1967
The effect of hydroxyurea on erythropoiesis, erythrocyte survival, and erythrokinetics in the rabbit.
    Cancer research, 1968, Volume: 28, Issue:10

    Topics: Anemia; Anemia, Hemolytic; Animals; Biological Transport; Blood Volume; Chromium Isotopes; Erythrocy

1968