hydroxyurea has been researched along with Aging in 33 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An attempt was made in 10 patients to reduce marrow hyperplasia by using hydroxyurea." | 3.70 | Bone pain in thalassaemia: assessment of DEXA and MRI findings. ( Angastiniotis, M; Aristidou, K; Eracleous, E; Kanakas, A; Pavlides, N; Posporis, T; Yerakaris, M, 1998) |
| "Hydroxyurea (HU) was started at diagnosis in 32 "symptomatic" patients and in 33 patients aged >70 years." | 2.74 | Decisional flow with a scoring system to start platelet-lowering treatment in patients with essential thrombocythemia: long-term results. ( Alimena, G; Biondo, F; Breccia, M; Carmosino, I; Fama, A; Latagliata, R; Mazzucconi, MG; Napoleone, L; Petti, MC; Rago, A; Santoro, C; Spadea, A; Stefanizzi, C; Volpicelli, P; Vozella, F, 2009) |
| " From the results of the present study, it is concluded that there is no pharmacokinetic basis for alteration of zileuton dosage schedules in elderly patients." | 2.68 | The pharmacokinetics of zileuton in healthy young and elderly volunteers. ( Awni, WM; Braeckman, RA; Cavannaugh, JH; Granneman, GR; Locke, CS; Machinist, JM, 1995) |
| "Hydroxyurea was given to patients with ET with a positive history for major vascular complications or with an extreme thrombocytosis." | 1.30 | Acute coronary disease in essential thrombocythemia and polycythemia vera. ( Girolami, A; Randi, ML; Rinaldi, V; Rossi, C; Zerbinati, P, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (51.52) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daniele, S | 1 |
| Da Pozzo, E | 1 |
| Iofrida, C | 1 |
| Martini, C | 1 |
| Zhai, Y | 1 |
| Wei, R | 1 |
| Liu, J | 1 |
| Wang, H | 1 |
| Cai, W | 1 |
| Zhao, M | 1 |
| Hu, Y | 1 |
| Wang, S | 1 |
| Yang, T | 1 |
| Liu, X | 1 |
| Yang, J | 1 |
| Liu, S | 1 |
| Latagliata, R | 1 |
| Rago, A | 1 |
| Spadea, A | 1 |
| Santoro, C | 1 |
| Carmosino, I | 1 |
| Breccia, M | 1 |
| Napoleone, L | 1 |
| Fama, A | 1 |
| Biondo, F | 1 |
| Volpicelli, P | 1 |
| Vozella, F | 1 |
| Stefanizzi, C | 1 |
| Petti, MC | 1 |
| Alimena, G | 1 |
| Mazzucconi, MG | 1 |
| Orsburn, B | 1 |
| Escudero, B | 1 |
| Prakash, M | 1 |
| Gesheva, S | 1 |
| Liu, G | 1 |
| Huso, DL | 1 |
| Franco, S | 1 |
| Burhans, WC | 1 |
| Weinberger, M | 1 |
| Losada, R | 1 |
| Bravo, I | 1 |
| Capildeo, K | 1 |
| Charles, K | 1 |
| Yogev, O | 1 |
| Anzi, S | 1 |
| Inoue, K | 1 |
| Shaulian, E | 1 |
| Eggleston, B | 1 |
| Patience, M | 1 |
| Edwards, S | 1 |
| Adamkiewicz, T | 1 |
| Buchanan, GR | 1 |
| Davies, SC | 1 |
| Dickerhoff, R | 1 |
| Donfield, S | 1 |
| Feig, SA | 1 |
| Giller, RH | 1 |
| Haight, A | 1 |
| Horan, J | 1 |
| Hsu, LL | 1 |
| Kamani, N | 1 |
| Lane, P | 1 |
| Levine, JE | 1 |
| Margolis, D | 1 |
| Moore, TB | 1 |
| Ohene-Frempong, K | 1 |
| Redding-Lallinger, R | 1 |
| Roberts, IA | 1 |
| Rogers, ZR | 1 |
| Sanders, JE | 1 |
| Scott, JP | 1 |
| Sleight, B | 1 |
| Thompson, AA | 1 |
| Sullivan, KM | 1 |
| Walters, MC | 1 |
| Prabhakar, V | 1 |
| Kaplay, M | 1 |
| Rao, KS | 1 |
| Sidorenko, AV | 2 |
| Andrianova, LF | 2 |
| Gjedde, SB | 1 |
| Dorsky, RI | 1 |
| Rapaport, DH | 1 |
| Harris, WA | 1 |
| Braeckman, RA | 2 |
| Granneman, GR | 2 |
| Locke, CS | 1 |
| Machinist, JM | 2 |
| Cavannaugh, JH | 1 |
| Awni, WM | 2 |
| Cavanaugh, JH | 1 |
| Chu, SY | 1 |
| Patterson, KJ | 1 |
| Korver, DR | 1 |
| Wakenell, P | 1 |
| Klasing, KC | 1 |
| Rossi, C | 1 |
| Randi, ML | 1 |
| Zerbinati, P | 1 |
| Rinaldi, V | 1 |
| Girolami, A | 1 |
| Angastiniotis, M | 1 |
| Pavlides, N | 1 |
| Aristidou, K | 1 |
| Kanakas, A | 1 |
| Yerakaris, M | 1 |
| Eracleous, E | 1 |
| Posporis, T | 1 |
| Frasca, D | 1 |
| Barattini, P | 1 |
| Tirindelli, D | 1 |
| Guidi, L | 1 |
| Bartoloni, C | 1 |
| Errani, A | 1 |
| Costanzo, M | 1 |
| Tricerri, A | 1 |
| Pierelli, L | 1 |
| Doria, G | 1 |
| Griffiths, TD | 1 |
| Tolmach, LJ | 1 |
| Nariuchi, H | 1 |
| Adler, WH | 1 |
| Tret'iak, TM | 1 |
| Vilenchik, MM | 1 |
| Terpilovskaia, ON | 1 |
| Tiras, NF | 1 |
| Raju, MR | 1 |
| Tobey, RA | 1 |
| Jett, JH | 1 |
| Walters, RA | 1 |
| Lampidis, TJ | 1 |
| Schaiberger, GE | 1 |
| Macsyuk, TV | 1 |
| Butenko, GM | 1 |
| Datta, MC | 1 |
| Dowla, HA | 1 |
| Spears, HJ | 1 |
| Licastro, F | 1 |
| Walford, RL | 1 |
| Smith, TA | 1 |
| Neary, D | 1 |
| Itzhaki, RF | 1 |
| Fong, S | 1 |
| Gilbertson, TA | 1 |
| Hueniken, RJ | 1 |
| Singhal, SK | 1 |
| Vaughan, JH | 1 |
| Carson, DA | 1 |
| Lévy, M | 1 |
| Vieira, P | 1 |
| Coutinho, A | 1 |
| Freitas, A | 1 |
| Lipman, JM | 1 |
| Sokoloff, L | 1 |
| Reitz, MS | 1 |
| Sanadi, DR | 1 |
| Mauro, F | 1 |
| Madoc-Jones, H | 1 |
| Sung, SC | 1 |
3 trials available for hydroxyurea and Aging
| Article | Year |
|---|---|
Decisional flow with a scoring system to start platelet-lowering treatment in patients with essential thrombocythemia: long-term results.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Platelets; Cardiovascular Diseases; Clinical Protocols; | 2009 |
Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia.
Topics: Age Factors; Aging; Anemia, Sickle Cell; Antisickling Agents; Body Height; Bone Marrow Transplantati | 2007 |
The pharmacokinetics of zileuton in healthy young and elderly volunteers.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Chromatography, H | 1995 |
30 other studies available for hydroxyurea and Aging
| Article | Year |
|---|---|
Human Neural Stem Cell Aging Is Counteracted by α-Glycerylphosphorylethanolamine.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Aging; Annexin A5; Apoptosis; Cell Pro | 2016 |
Drug-induced premature senescence model in human dental follicle stem cells.
Topics: Age Factors; Aging; Apoptosis; beta-Galactosidase; Cell Cycle Checkpoints; Cell Differentiation; Cel | 2017 |
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Topics: Aging; Animals; B-Lymphocytes; Chromosomal Proteins, Non-Histone; DNA; DNA Breaks, Double-Stranded; | 2010 |
Histone genes, DNA replication, apoptosis and aging: what are the connections?
Topics: Aging; Apoptosis; DNA Replication; Fungal Proteins; Histones; Hydroxyurea; Nucleic Acid Synthesis In | 2010 |
Is the group of older sickle cell disease patients from Trinidad and Tobago different?
Topics: Adult; Aged; Aging; Anemia, Sickle Cell; Antisickling Agents; Blood Transfusion; Female; Foot Ulcer; | 2006 |
Induction of transcriptionally active Jun proteins regulates drug-induced senescence.
Topics: Aging; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cells, Cultured; Cy | 2006 |
Hydroxyurea inhibition of thymidine kinase is dependent on the developmental stage of the brain region.
Topics: Aging; Animals; Brain; DNA; Hydroxyurea; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Thymidin | 1984 |
[Effect of hydroxyurea on the number of hematopoietic stem cells, stromal cell precursors and cell precursors of thymus lymphoid tissue in the bone marrow of mice during aging].
Topics: Aging; Animals; Bone Marrow; Bone Marrow Cells; Cell Count; Colony-Forming Units Assay; Female; Guin | 1984 |
B-lymphocyte colony forming cells in the thymus of AKR mice.
Topics: Aging; Animals; B-Lymphocytes; Cell Separation; Cells, Cultured; Clone Cells; Complement System Prot | 1980 |
Xotch inhibits cell differentiation in the Xenopus retina.
Topics: Aging; Animals; Aphidicolin; Cell Differentiation; Cell Division; Embryo, Nonmammalian; Gastrula; Ge | 1995 |
The effect of mild or moderate hepatic impairment (cirrhosis) on the pharmacokinetics of zileuton.
Topics: Administration, Oral; Adult; Aging; Blood Proteins; Chromatography, High Pressure Liquid; Dose-Respo | 1995 |
Dietary fish oil or lofrin, a 5-lipoxygenase inhibitor, decrease the growth-suppressing effects of coccidiosis in broiler chicks.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Cecum; Chickens; Coccidiosis; Corn Oil; Dietary F | 1997 |
Acute coronary disease in essential thrombocythemia and polycythemia vera.
Topics: Adult; Aged; Aging; Antisickling Agents; Aspirin; Female; Follow-Up Studies; Humans; Hydroxyurea; Ma | 1998 |
Bone pain in thalassaemia: assessment of DEXA and MRI findings.
Topics: Absorptiometry, Photon; Adult; Aging; beta-Thalassemia; Blood Transfusion; Bone and Bones; Bone Dens | 1998 |
Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC).
Topics: Adult; Aged; Aged, 80 and over; Aging; Antigens, Nuclear; Cells, Cultured; Cytokines; DNA; DNA Helic | 1999 |
Age-dependence of the x-ray-induced deficiency in DNA synthesis in HeLa S3 cells during Generation 1.
Topics: Aging; Cell Division; DNA; DNA, Neoplasm; Dose-Response Relationship, Radiation; Floxuridine; HeLa C | 1975 |
Dissociation between proliferation and antibody formation by old mouse spleen cells in response to LPS stimulation.
Topics: Aging; Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Dinitrobenzenes; Hydroxyurea; Immune | 1979 |
[DNA synthesis in rat brain nerve cells].
Topics: Aging; Animals; Brain; DNA; Hydroxyurea; Liver; Neurons; Rats | 1976 |
Age response for line CHO Chinese hamster cells exposed to x-irradiation and alpha particles from plutonium.
Topics: Aging; Alpha Particles; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Hydroxyurea; M | 1975 |
Age-related loss of DNA repair synthesis in isolated rat myocardial cells.
Topics: Aging; Animals; DNA; DNA Repair; Female; Hydroxyurea; Myocardium; Radiation Effects; Rats; Ultraviol | 1975 |
Stromal hemopoietic microenvironment in aging.
Topics: Aging; Animals; Bone Marrow; Colony-Forming Units Assay; Female; Fibroblasts; Hematopoiesis; Hematop | 1990 |
Hydroxyurea-induced switching of hemoglobin proportions toward newborn values in normal adult rats is blocked by acetylsalicylic acid.
Topics: Aging; Anemia; Animals; Animals, Newborn; Aspirin; Fetal Hemoglobin; Hemoglobins; Hydroxyurea; Rats; | 1989 |
Modulatory effect of nicotinamide on unscheduled DNA synthesis in lymphocytes from young and old mice.
Topics: Aging; Animals; Cell Survival; Cells, Cultured; Concanavalin A; DNA Replication; Hydroxyurea; Lympho | 1986 |
DNA repair in lymphocytes from young and old individuals and from patients with Alzheimer's disease.
Topics: Adult; Aged; Aging; Alzheimer Disease; Cell Survival; DNA; DNA Repair; Female; Gamma Rays; Humans; H | 1987 |
IgM rheumatoid factor autoantibody and immunoglobulin-producing precursor cells in the bone marrow of humans.
Topics: Aging; Antibodies, Monoclonal; Antibody-Producing Cells; Antigens, Differentiation, B-Lymphocyte; An | 1985 |
The majority of "natural" immunoglobulin-secreting cells are short-lived and the progeny of cycling lymphocytes.
Topics: Aging; Animals; Antibody-Producing Cells; B-Lymphocytes; Bone Marrow Cells; Cell Cycle; Cell Surviva | 1987 |
DNA repair by articular chondrocytes. III. Unscheduled DNA synthesis following ultraviolet light irradiation of resting cartilage.
Topics: Aging; Animals; Aphidicolin; Autoradiography; Body Water; Cartilage, Articular; Cells, Cultured; Dit | 1985 |
An aspect of translational control of protein synthesis in aging: changes in the isoaccepting forms of tRNA in Turbatrix aceti.
Topics: Aging; Animals; Chromatography; Hydroxyurea; Mitochondria; Nematoda; Protein Biosynthesis; RNA, Tran | 1972 |
Age response to x-radiation of murine lymphoma cells synchronized in vivo.
Topics: Aging; Animals; Biological Assay; Cell Division; Cell Line; Clone Cells; HeLa Cells; Hydroxyurea; Ly | 1969 |
DNA synthesis in the developing rat brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System | 1969 |