hydroxyurea has been researched along with Aggressive Systemic Mastocytosis in 9 studies
Aggressive Systemic Mastocytosis: A form of systemic mastocytosis in which patients have impaired organ functions due to multifocal infiltrates of pathological MAST CELLS in bone marrow, liver, spleen, gastrointestinal tract, or skeletal system. The cytomorphology shows a low to high grade.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combination of IFN-alpha and hydroxyurea is very useful and allows dosage reduction of IFN-alpha and better control of hypereosinophilia than with either agent alone." | 2.43 | Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis. ( Butterfield, JH, 2005) |
| "Indolent systemic mastocytosis is a group of rare diseases for which reliable predictors of progression and outcome are still lacking." | 1.35 | Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients. ( Almeida, J; Alvarez-Twose, I; Bellas, C; Escribano, L; García-Cosío, M; Garcia-Montero, A; Jara-Acevedo, M; Núñez, R; Orfao, A; Sánchez-Muñoz, L; Teodósio, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Pardanani, A | 4 |
| Escribano, L | 1 |
| Alvarez-Twose, I | 1 |
| Sánchez-Muñoz, L | 1 |
| Garcia-Montero, A | 1 |
| Núñez, R | 1 |
| Almeida, J | 1 |
| Jara-Acevedo, M | 1 |
| Teodósio, C | 1 |
| García-Cosío, M | 1 |
| Bellas, C | 1 |
| Orfao, A | 1 |
| Lim, KH | 1 |
| Butterfield, JH | 2 |
| Li, CY | 1 |
| Tefferi, A | 1 |
| Gotlib, J | 1 |
| Liu, AY | 1 |
| Lowe, RC | 1 |
| Levy, BD | 1 |
| Katz, JT | 1 |
| Loscalzo, J | 1 |
| Florian, S | 1 |
| Esterbauer, H | 1 |
| Binder, T | 1 |
| Müllauer, L | 1 |
| Haas, OA | 1 |
| Sperr, WR | 1 |
| Sillaber, C | 1 |
| Valent, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Quality of Life and Disease-related Symptoms in Individuals With Systemic Mastocytosis[NCT06065007] | 400 participants (Anticipated) | Observational | 2023-10-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydroxyurea and Aggressive Systemic Mastocytosis
| Article | Year |
|---|---|
Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management.
Topics: Adult; Algorithms; Animals; Bone Marrow; Disease Management; Disease Models, Animal; Drugs, Investig | 2021 |
Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management.
Topics: Adrenal Cortex Hormones; Adult; Bone Marrow Examination; Cell Lineage; Cladribine; Clinical Trials a | 2012 |
Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Movement; Cell Prolifera | 2005 |
6 other studies available for hydroxyurea and Aggressive Systemic Mastocytosis
| Article | Year |
|---|---|
Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients.
Topics: Adolescent; Adult; Aged; Antiviral Agents; beta 2-Microglobulin; Disease Progression; Enzyme Inhibit | 2009 |
Cytoreductive therapy in 108 adults with systemic mastocytosis: Outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Bone Marrow; Cladribine; Dioxygenases; DNA Mutational An | 2009 |
On being metachromatic: mystique and misunderstanding in mastocytosis.
Topics: Benzamides; Cell Shape; Cladribine; Cytoplasmic Granules; Humans; Hydroxyurea; Imatinib Mesylate; In | 2009 |
Clinical problem-solving. A rash hypothesis.
Topics: Adult; Biopsy; Blood Cell Count; Bone Marrow; Colon; Diagnosis, Differential; Diarrhea; Drug Therapy | 2010 |
Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management.
Topics: Adult; Antineoplastic Agents; Benzamides; Bone Marrow; Cladribine; Dasatinib; Disease-Free Survival; | 2011 |
Systemic mastocytosis (SM) associated with chronic eosinophilic leukemia (SM-CEL): detection of FIP1L1/PDGFRalpha, classification by WHO criteria, and response to therapy with imatinib.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benz | 2006 |