hydroxyurea has been researched along with Adrenoleukodystrophy in 1 studies
Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brose, RD | 1 |
| Shin, G | 1 |
| McGuinness, MC | 1 |
| Schneidereith, T | 1 |
| Purvis, S | 1 |
| Dong, GX | 1 |
| Keefer, J | 1 |
| Spencer, F | 1 |
| Smith, KD | 1 |
1 other study available for hydroxyurea and Adrenoleukodystrophy
| Article | Year |
|---|---|
Activation of the stress proteome as a mechanism for small molecule therapeutics.
Topics: Adrenoleukodystrophy; Cell Line; Drug Therapy; Humans; Hydroxamic Acids; Hydroxyurea; Isothiocyanate | 2012 |