Page last updated: 2024-10-28

hydroxyurea and Acute Lymphoid Leukemia

hydroxyurea has been researched along with Acute Lymphoid Leukemia in 16 studies

Research Excerpts

ExcerptRelevanceReference
"To analyze the results of idarubicin (IDA)- versus etoposide (VP16)-intensified myeloablative conditioning regimen in allogeneic hematopoietic stem cell transplantation (allo-SCT) for high-risk acute leukemia."7.75A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia. ( Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P, 2009)
" Although he was treated with prednisolone and hydroxyurea, marked eosinophilia persisted and lymphoblasts gradually increased in the bone marrow."4.78Hypereosinophilic syndrome evolving to acute lymphoblastic leukemia. ( Sanada, M; Takai, K, 1991)
"To analyze the results of idarubicin (IDA)- versus etoposide (VP16)-intensified myeloablative conditioning regimen in allogeneic hematopoietic stem cell transplantation (allo-SCT) for high-risk acute leukemia."3.75A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia. ( Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P, 2009)
"Hydroxyurea was implicated in 51% of cases."2.44Dermatomyositis induced by drug therapy: a review of case reports. ( Gottlieb, AB; Seidler, AM, 2008)
"The hydroxyurea-induced increase in transferrin receptor was abrogated by transferrin-iron."1.29Effect of hydroxyurea on cellular iron metabolism in human leukemic CCRF-CEM cells: changes in iron uptake and the regulation of transferrin receptor and ferritin gene expression following inhibition of DNA synthesis. ( Chitambar, CR; Wereley, JP, 1995)
"Essential thrombocythemia is a myeloproliferative disorder that infrequently evolves into acute leukemia."1.29Acute lymphoblastic leukemia in a case of essential thrombocythemia. ( Litz, CE; Woronzoff-Dashkoff, KK, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (56.25)18.2507
2000's5 (31.25)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Easmon, J1
Pürstinger, G1
Heinisch, G1
Roth, T1
Fiebig, HH1
Holzer, W1
Jäger, W1
Jenny, M1
Hofmann, J1
Aygun, B1
Seidler, AM1
Gottlieb, AB1
Li, QB1
Li, L1
You, Y1
Chen, ZC1
Xia, LH1
Zou, P1
Mathews, CK1
Efferth, T1
Sauerbrey, A1
Steinbach, D1
Gebhart, E1
Drexler, HG1
Miyachi, H1
Chitambar, CR3
Becker, CM1
Zintl, F1
Humeny, A1
Inhorn, RC1
Aster, JC1
Roach, SA1
Slapak, CA1
Soiffer, R1
Tantravahi, R1
Stone, RM1
Wereley, JP1
Chamberlain, MC1
Xu, YZ1
Plunkett, W1
Woronzoff-Dashkoff, KK1
Litz, CE1
Higashigawa, M1
Hori, H1
Hirayama, M1
Kawasaki, H1
Ido, M1
Azuma, E1
Sakurai, M1
Myette, MS1
Elford, HL1
Savage, DG1
Antman, KH1
Takai, K1
Sanada, M1
Karlsson, A1
Reichard, P1
Eckstein, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised Multicentre Phase IV Study to Compare Glivec® (Imatinib Mesylate, STI571) in Monotherapy Versus Glivec® in Combination With Interferon Alpha at Low Doses in the Treatment of Newly-Diagnosed Chronic-Phase Chronic Myeloid Leukaemia[NCT00390897]Phase 4360 participants Interventional2003-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for hydroxyurea and Acute Lymphoid Leukemia

ArticleYear
Dermatomyositis induced by drug therapy: a review of case reports.
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:5

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoimmune Diseases; Cyclophosphamide; Dermatomyositis; Etopos

2008
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
    Blood, 1995, Apr-01, Volume: 85, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Prot

1995
Imatinib mesylate--a new oral targeted therapy.
    The New England journal of medicine, 2002, Feb-28, Volume: 346, Issue:9

    Topics: Administration, Oral; Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Drug Resistance;

2002
Hypereosinophilic syndrome evolving to acute lymphoblastic leukemia.
    International journal of hematology, 1991, Volume: 54, Issue:3

    Topics: Adult; Blood Proteins; Endocardium; Endomyocardial Fibrosis; Eosinophil Granule Proteins; Eosinophil

1991

Other Studies

12 other studies available for hydroxyurea and Acute Lymphoid Leukemia

ArticleYear
Synthesis, cytotoxicity, and antitumor activity of copper(II) and iron(II) complexes of (4)N-azabicyclo[3.2.2]nonane thiosemicarbazones derived from acyl diazines.
    Journal of medicinal chemistry, 2001, Jun-21, Volume: 44, Issue:13

    Topics: Antineoplastic Agents; Apoptosis; Body Weight; Burkitt Lymphoma; Carcinoma, Large Cell; Cell Cycle;

2001
Hydroxyurea for ALL children with sickle cell anemia: What can we learn from Africa?
    Pediatric blood & cancer, 2020, Volume: 67, Issue:4

    Topics: Africa; Anemia, Sickle Cell; Antisickling Agents; Child; Humans; Hydroxyurea; Precursor Cell Lymphob

2020
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combine

2009
DNA synthesis as a therapeutic target: the first 65 years.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:6

    Topics: Aminopterin; Antimetabolites, Antineoplastic; DNA Replication; Fluorouracil; Folic Acid; Folic Acid

2012
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control St

2003
Effect of hydroxyurea on cellular iron metabolism in human leukemic CCRF-CEM cells: changes in iron uptake and the regulation of transferrin receptor and ferritin gene expression following inhibition of DNA synthesis.
    Cancer research, 1995, Oct-01, Volume: 55, Issue:19

    Topics: Antineoplastic Agents; DNA; Ferritins; Gene Expression Regulation; Humans; Hydroxyurea; Iron; Iron-R

1995
Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.
    Cancer, 1994, Mar-15, Volume: 73, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; C

1994
Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells.
    The Journal of biological chemistry, 1993, Oct-25, Volume: 268, Issue:30

    Topics: Aphidicolin; Carbon Radioisotopes; Cell Cycle; Cytarabine; Deoxycytidine; Deoxyuridine; DNA Replicat

1993
Acute lymphoblastic leukemia in a case of essential thrombocythemia.
    American journal of clinical pathology, 1996, Volume: 106, Issue:2

    Topics: Aged; Antigens, CD; Blast Crisis; Bone Marrow; Female; Humans; Hydroxyurea; Lymphocyte Activation; P

1996
Salvage therapy for relapsed or refractory childhood acute lymphocytic leukemia by alternative administration a lymphoid- and myeloid-directed chemotherapeutic regimen consisting of dual modulation of ara-C, hydroxyurea, and etoposide.
    Leukemia research, 1997, Volume: 21, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Co

1997
Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells.
    Cancer letters, 1998, Jul-17, Volume: 129, Issue:2

    Topics: Antineoplastic Agents; Benzamidines; Cell Division; Deoxycytidine; Drug Synergism; Enzyme Inhibitors

1998
The metabolism of 3'-azido-2',3'-dideoxyguanosine in CEM cells.
    Biochemical and biophysical research communications, 1990, Jan-15, Volume: 166, Issue:1

    Topics: Antiviral Agents; Cell Line; Deoxyribonucleotides; Dideoxynucleosides; DNA, Neoplasm; Humans; Hydrox

1990