hydroxyurea has been researched along with Acute Confusional Senile Dementia in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Lipoxygenase (5LO) is upregulated in Alzheimer's disease (AD) and in vivo modulates the amyloidotic phenotype of amyloid precursor protein transgenic mice." | 1.40 | Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease. ( Chu, J; Giannopoulos, PF; Joshi, YB; Kirby, LG; Li, JG; Praticò, D; Sperow, M, 2014) |
| "Zileuton treatment did not induce any change in the steady state levels of amyloid-β precursor protein (APP), BACE1 or ADAM10." | 1.37 | Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase. ( Chu, J; Praticò, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, JG | 3 |
| Barrero, C | 1 |
| Merali, S | 1 |
| Praticò, D | 5 |
| Brose, RD | 1 |
| Lehrmann, E | 1 |
| Zhang, Y | 1 |
| Reeves, RH | 1 |
| Smith, KD | 1 |
| Mattson, MP | 1 |
| Giannopoulos, PF | 1 |
| Chu, J | 3 |
| Joshi, YB | 1 |
| Sperow, M | 1 |
| Kirby, LG | 1 |
| Di Meco, A | 1 |
| Lauretti, E | 1 |
| Vagnozzi, AN | 1 |
| Smith, TA | 1 |
| Neary, D | 1 |
| Itzhaki, RF | 1 |
7 other studies available for hydroxyurea and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Diet; DNA Methylation; Female; | 2017 |
Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Cells, Cultured; Disease Models | 2018 |
Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Arachidonate 5-Lipoxygenase | 2014 |
Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2013 |
Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Amyloidogenic Proteins; Animals; Arachidona | 2014 |
Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Fe | 2011 |
DNA repair in lymphocytes from young and old individuals and from patients with Alzheimer's disease.
Topics: Adult; Aged; Aging; Alzheimer Disease; Cell Survival; DNA; DNA Repair; Female; Gamma Rays; Humans; H | 1987 |