hydroxysafflor-yellow-a has been researched along with Pneumonia* in 1 studies
1 other study(ies) available for hydroxysafflor-yellow-a and Pneumonia
| Article | Year |
|---|---|
Protective effect of hydroxysafflor yellow A on bleomycin- induced pulmonary inflammation and fibrosis in rats.
To observe the effect of hydroxysafflor yellow A (HSYA), an active ingredient of a traditional Chinese herbal medicine Carthamus tinctorius L., on lung inflflammation and pulmonary fibrosis induced by bleomycin (BLM) in rats.. Animals were divided into 6 groups including normal group, model group, three HSYA groups and dexamethasone (DXM) group. Three doses of HSYA (35.6, 53.3, and 80.0 mg•kg. On the 7th day after BLM administration, lung tissue showed serious inflammation. Treatment with HSYA or DXM ameliorated lung inflammation. After treatment with HSYA or DXM, oxygen partial pressure (PaO. HSYA could alleviate acute lung inflflammation and chronic pulmonary fibrosis induced by BLM in rats. Topics: Actins; Animals; Bleomycin; Chalcone; Collagen Type I; Interleukin-1beta; Interleukin-6; Lung; Lung Injury; Oxygen; Pneumonia; Pulmonary Fibrosis; Quinones; Rats, Wistar; RNA, Messenger; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2018 |