Compounds > hydroxysafflor-yellow-a

hydroxysafflor-yellow-a and Diabetes-Mellitus--Type-2

hydroxysafflor-yellow-a has been researched along with Diabetes-Mellitus--Type-2* in 1 studies

Other Studies

1 other study(ies) available for hydroxysafflor-yellow-a and Diabetes-Mellitus--Type-2

ArticleYear
Molecular dynamics simulation integrating the inhibition kinetics of hydroxysafflor yellow A on α-glucosidase.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:4

    Inhibition of α-glucosidase has attracted the attention of researchers due to its connection to type-2 diabetes. Hydroxysafflor yellow A (HSYA) extracted from Carthamus tinctorius L. is a natural antioxidant used in traditional Chinese medicine. In this study, the effect of HSYA on α-glucosidase was evaluated using inhibitory kinetics based on the antioxidant properties of HSYA and by performing computational simulation integration methods. HSYA reversibly inhibited α-glucosidase in a competitive inhibition manner and the evaluated kinetic parameters were IC

    Topics: alpha-Glucosidases; Antioxidants; Carthamus; Chalcone; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Humans; Kinetics; Medicine, Chinese Traditional; Molecular Dynamics Simulation; Quinones

2018